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IMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003847

Arc-Vir

IMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003847

Quality

81.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-94
PDB
Domain cluster: representative
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.87 81.0 7.39e-01 100.0% 85.6%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.84 77.0 6.79e-01 100.0% 87.8%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.83 76.0 6.66e-01 100.0% 85.7%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.82 74.0 5.82e-01 96.7% 67.4%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.81 73.0 6.32e-01 97.8% 83.2%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.81 64.0 6.26e-01 96.7% 77.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.80 73.0 6.75e-01 97.8% 85.0%
7ru9C01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 52.0 3.61e-01 74.7% 22.5%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.79 70.0 6.19e-01 97.8% 80.9%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 55.0 6.00e-01 72.5% 93.3%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.77 61.0 6.37e-01 96.7% 94.0%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.76 67.0 5.24e-01 96.7% 61.3%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.76 66.0 6.18e-01 96.7% 86.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 52.0 5.71e-01 70.3% 94.6%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.76 68.0 6.05e-01 96.7% 93.6%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.75 65.0 5.96e-01 96.7% 84.9%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.75 65.0 5.18e-01 96.7% 67.4%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.74 51.0 5.82e-01 79.1% 98.5%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.74 52.0 4.85e-01 73.6% 61.9%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 65.0 5.91e-01 95.6% 79.7%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.73 64.0 5.71e-01 96.7% 76.6%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 50.0 4.41e-01 70.3% 58.7%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 50.0 5.04e-01 71.4% 76.3%
2wmoA01 1.25.40.410 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A 0.72 51.0 4.49e-01 73.6% 64.2%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.72 60.0 5.53e-01 91.2% 82.9%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 50.0 4.97e-01 73.6% 77.3%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 53.0 5.27e-01 76.9% 92.5%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.71 50.0 5.41e-01 72.5% 90.9%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.71 60.0 5.45e-01 95.6% 92.1%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.70 50.0 4.89e-01 74.7% 73.0%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.70 60.0 4.96e-01 94.5% 90.2%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.69 62.0 5.64e-01 97.8% 75.6%
4ebjA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 61.0 5.39e-01 96.7% 78.5%
1i5nB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.69 58.0 5.33e-01 96.7% 78.2%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 58.0 5.39e-01 96.7% 95.8%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 59.0 5.44e-01 98.9% 97.5%
3b4qA00 1.10.1200.100 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae 0.68 51.0 5.26e-01 100.0% 82.8%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.67 51.0 5.32e-01 80.2% 96.5%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 57.0 5.26e-01 96.7% 95.9%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 47.0 4.31e-01 75.8% 77.1%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 46.0 4.48e-01 74.7% 89.8%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.64 46.0 4.50e-01 75.8% 90.2%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 41.0 4.94e-01 80.2% 96.8%
3fmsA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.63 55.0 4.79e-01 98.9% 90.8%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 46.0 4.42e-01 75.8% 90.3%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.62 51.0 4.49e-01 86.8% 92.2%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 45.0 4.40e-01 76.9% 87.3%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 42.0 4.59e-01 70.3% 97.3%
2o5vA02 1.20.1050.90 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › RecF/RecN/SMC, N-terminal domain 0.62 55.0 4.47e-01 100.0% 71.6%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.62 44.0 4.51e-01 73.6% 89.7%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.61 54.0 4.57e-01 100.0% 84.6%
4fx5A03 1.20.120.1690 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 52.0 5.07e-01 96.7% 86.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 44.0 4.22e-01 76.9% 87.7%
3kbtA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 42.0 3.02e-01 73.6% 33.8%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 48.0 4.36e-01 86.8% 69.7%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 41.0 3.99e-01 90.1% 67.3%
3sz7A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 44.0 3.68e-01 89.0% 50.3%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 50.0 3.56e-01 95.6% 71.2%
4wnfA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 49.0 3.48e-01 98.9% 50.6%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.53 46.0 3.64e-01 100.0% 55.0%
4u72A01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 46.0 3.44e-01 100.0% 78.4%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3791448 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.83 74.0 6.93e-01 96.7% 95.5%
4338603 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.82 75.0 6.72e-01 100.0% 93.6%
3801658 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.82 74.0 6.44e-01 97.8% 78.5%
3990091 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.82 63.0 6.65e-01 95.6% 91.3%
3971908 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.81 72.0 6.41e-01 94.5% 80.8%
5060248 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.81 58.0 6.44e-01 74.7% 95.7%
3806738 192.29.1.104 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 0.80 71.0 6.35e-01 95.6% 94.4%
4018701 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.79 72.0 4.88e-01 100.0% 45.6%
5005401 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.79 68.0 5.60e-01 95.6% 76.4%
5082191 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.78 70.0 6.78e-01 96.7% 92.0%
5041256 601.4.1.91 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF30769 0.78 69.0 6.62e-01 96.7% 99.0%
4024396 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.77 53.0 4.66e-01 71.4% 91.9%
5040635 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.77 69.0 6.33e-01 96.7% 85.2%
4987361 601.2.1.0 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.76 67.0 6.09e-01 96.7% 77.5%
5077945 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.75 65.0 5.98e-01 95.6% 93.3%
3603138 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 60.0 5.32e-01 85.7% 99.2%
3615115 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.74 52.0 3.89e-01 72.5% 32.7%
4032961 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.74 64.0 6.61e-01 94.5% 100.0%
4056285 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.73 51.0 5.09e-01 72.5% 72.6%
3354926 9001.1.1.1 alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TRAM_LAG1_CLN8 0.72 51.0 4.61e-01 72.5% 89.2%
4436309 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.71 53.0 5.23e-01 78.0% 75.8%
3548125 3930.1.1.2 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RIG-I_C 0.71 48.0 4.28e-01 70.3% 50.8%
3735976 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 65.0 4.80e-01 100.0% 59.1%
4290271 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.71 50.0 5.11e-01 74.7% 77.8%
4038171 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.70 52.0 5.22e-01 78.0% 78.9%
4270503 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.70 48.0 4.97e-01 78.0% 75.3%
3430437 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.70 61.0 4.47e-01 96.7% 59.6%
4073605 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.69 53.0 3.82e-01 81.3% 68.9%
4063100 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.69 47.0 4.96e-01 72.5% 80.0%
3502219 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 60.0 5.76e-01 94.5% 86.7%
4474310 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.69 47.0 4.95e-01 71.4% 80.0%
3442159 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 50.0 5.01e-01 96.7% 73.7%
3781234 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.68 48.0 3.68e-01 72.5% 62.4%
3255143 630.1.1.0 a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.68 47.0 3.69e-01 71.4% 64.9%
3652677 601.18.1.13 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint 0.68 59.0 5.44e-01 95.6% 87.0%
3628716 109.4.1.898 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_leprecan 0.67 47.0 3.13e-01 72.5% 38.9%
3711125 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 58.0 4.57e-01 98.9% 97.1%
5031714 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.67 55.0 5.35e-01 91.2% 100.0%
3785563 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 59.0 5.46e-01 97.8% 86.1%
3713312 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 57.0 4.50e-01 98.9% 97.1%
3269578 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 47.0 3.62e-01 75.8% 36.2%
3703991 109.4.1.1317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C 0.65 45.0 2.65e-01 71.4% 9.7%
3256134 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 51.0 4.60e-01 83.5% 72.5%
3931278 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 53.0 5.11e-01 96.7% 80.6%
4663621 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.61 44.0 3.91e-01 74.7% 86.9%
5054427 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.60 49.0 4.32e-01 97.8% 58.6%
3413075 109.4.1.1317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C 0.59 46.0 2.80e-01 85.7% 35.4%
3710252 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 48.0 3.25e-01 85.7% 28.1%
3240465 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 41.0 3.80e-01 72.5% 81.7%
3606475 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 50.0 4.49e-01 89.0% 70.0%
5053943 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.58 50.0 4.20e-01 95.6% 56.0%
3875102 109.4.1.1317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C 0.57 48.0 2.81e-01 91.2% 52.7%
4881789 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.55 47.0 4.80e-01 96.7% 94.3%
3253050 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.53 47.0 3.65e-01 95.6% 90.3%
3587541 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.52 36.0 3.71e-01 74.7% 78.9%
4996368 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.51 44.0 2.96e-01 100.0% 53.6%
3736616 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.50 43.0 3.02e-01 100.0% 31.5%
D2 high residues 97-193
PDB
Domain cluster: representative
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.86 79.0 7.16e-01 100.0% 85.2%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.85 79.0 6.45e-01 100.0% 66.1%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.84 78.0 7.17e-01 99.0% 87.5%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.84 77.0 6.50e-01 100.0% 69.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.83 77.0 7.22e-01 100.0% 97.4%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.83 76.0 6.78e-01 100.0% 83.6%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.83 76.0 5.93e-01 100.0% 64.3%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.82 65.0 5.67e-01 82.5% 65.9%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.82 75.0 6.78e-01 100.0% 86.2%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.80 73.0 5.94e-01 100.0% 71.3%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.80 73.0 5.58e-01 100.0% 57.1%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.80 58.0 5.54e-01 75.3% 70.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.80 73.0 6.93e-01 100.0% 93.8%
2mgxA00 1.20.940.10 Mainly Alpha › Up-down Bundle › RNA Binding Protein, Prp18; Chain A › Functional domain of the splicing factor Prp18 0.79 48.0 4.26e-01 76.3% 44.3%
6klvB00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.79 72.0 4.72e-01 100.0% 47.8%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.78 71.0 6.61e-01 100.0% 88.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 60.0 4.79e-01 81.4% 86.7%
1st6A03 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.78 71.0 5.32e-01 100.0% 51.1%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.77 63.0 5.63e-01 88.7% 76.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.76 59.0 5.54e-01 81.4% 75.9%
3a7kB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.76 68.0 5.00e-01 100.0% 76.7%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 54.0 5.99e-01 74.2% 98.6%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.75 51.0 4.82e-01 75.3% 58.6%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 67.0 5.25e-01 100.0% 56.1%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.75 57.0 4.55e-01 80.4% 78.5%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.73 57.0 4.97e-01 81.4% 78.2%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.73 64.0 4.95e-01 97.9% 64.3%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 56.0 5.47e-01 81.4% 83.7%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.73 65.0 5.61e-01 100.0% 84.3%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 65.0 5.87e-01 97.9% 88.5%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.72 58.0 4.55e-01 86.6% 50.3%
7oq4Z01 1.20.120.950 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 0.71 59.0 5.91e-01 99.0% 87.8%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 54.0 4.68e-01 81.4% 64.7%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.70 51.0 4.96e-01 76.3% 95.5%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.69 54.0 5.66e-01 83.5% 98.8%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 53.0 4.06e-01 82.5% 73.8%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.68 52.0 4.50e-01 82.5% 65.6%
4ib4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 60.0 4.35e-01 100.0% 76.5%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 47.0 3.87e-01 73.2% 39.8%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.66 51.0 4.44e-01 81.4% 74.7%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.66 48.0 5.01e-01 76.3% 90.6%
2j0wA02 1.20.120.1320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain 0.66 54.0 5.55e-01 90.7% 94.6%
3dxpA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.66 48.0 3.65e-01 77.3% 70.8%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.65 44.0 4.78e-01 71.1% 92.4%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 58.0 4.61e-01 100.0% 83.3%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.64 45.0 4.83e-01 84.5% 88.9%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.64 56.0 5.15e-01 100.0% 87.5%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.63 42.0 4.53e-01 81.4% 81.5%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 45.0 5.05e-01 75.3% 98.6%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.63 55.0 4.78e-01 99.0% 75.2%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.63 46.0 4.03e-01 79.4% 82.8%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.62 50.0 4.94e-01 86.6% 84.5%
1n1bB02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 53.0 3.86e-01 99.0% 43.5%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.61 56.0 4.78e-01 100.0% 98.0%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 54.0 4.76e-01 100.0% 90.3%
5tgzA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 52.0 3.85e-01 100.0% 73.6%
1qgtB00 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.60 47.0 4.19e-01 91.8% 58.0%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 55.0 4.71e-01 100.0% 98.0%
1or4B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 41.0 3.50e-01 70.1% 76.6%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.60 53.0 5.11e-01 95.9% 96.3%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 41.0 3.62e-01 71.1% 83.9%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 49.0 2.97e-01 87.6% 15.1%
7d5qA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.59 53.0 4.30e-01 100.0% 62.6%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 40.0 3.56e-01 74.2% 84.9%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.55 47.0 4.30e-01 94.8% 86.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 48.0 4.67e-01 100.0% 94.4%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.54 49.0 4.80e-01 100.0% 91.6%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.52 42.0 3.91e-01 88.7% 75.8%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 42.0 3.90e-01 95.9% 81.1%
ECOD (80)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4928655 5069.1.1.6 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › COX15-CtaA 0.88 82.0 6.98e-01 100.0% 86.7%
3253938 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.88 82.0 7.71e-01 100.0% 94.8%
5009683 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.88 82.0 7.15e-01 100.0% 80.0%
3488339 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.88 65.0 6.97e-01 77.3% 96.5%
3529790 601.1.1.57 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 0.87 81.0 7.28e-01 100.0% 84.6%
4220561 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.87 81.0 7.26e-01 100.0% 83.7%
4102845 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.87 81.0 7.50e-01 100.0% 87.5%
3931312 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.86 80.0 7.40e-01 100.0% 93.3%
3251844 601.1.3.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B 0.85 79.0 6.47e-01 100.0% 67.1%
3249527 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.85 79.0 6.99e-01 100.0% 91.1%
3253935 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.85 79.0 7.30e-01 100.0% 92.5%
3498944 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.85 79.0 6.66e-01 100.0% 73.5%
3746892 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.85 67.0 5.92e-01 82.5% 63.0%
3272925 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.85 79.0 7.19e-01 100.0% 85.6%
3797268 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.85 79.0 6.70e-01 100.0% 76.0%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.85 78.0 7.25e-01 100.0% 92.5%
3255240 601.1.1.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS 0.85 79.0 6.47e-01 100.0% 66.7%
3862607 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.84 78.0 7.25e-01 100.0% 83.3%
3471903 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.84 78.0 6.38e-01 100.0% 67.6%
3798573 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.84 78.0 6.56e-01 100.0% 72.3%
1251943 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.84 78.0 7.11e-01 100.0% 91.2%
3514291 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.83 77.0 6.23e-01 100.0% 64.0%
3549920 601.1.2.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › TLN1-like_RS 0.83 77.0 6.42e-01 100.0% 73.1%
3901971 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.83 77.0 6.35e-01 100.0% 74.5%
3893417 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.83 76.0 6.79e-01 100.0% 83.0%
3762437 601.1.2.138 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CAS_C 0.83 76.0 5.96e-01 100.0% 56.6%
3520750 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.83 76.0 6.20e-01 100.0% 76.0%
3881919 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.83 76.0 5.92e-01 100.0% 56.0%
3871038 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.82 76.0 6.09e-01 100.0% 76.1%
3411201 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.82 75.0 6.07e-01 100.0% 63.9%
3931311 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.82 75.0 6.52e-01 100.0% 75.2%
3768053 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.82 76.0 6.38e-01 100.0% 82.6%
3471904 601.1.1.57 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 0.82 74.0 6.95e-01 97.9% 98.3%
3249523 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.81 75.0 6.94e-01 100.0% 95.8%
3858331 601.1.1.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS 0.81 75.0 6.33e-01 100.0% 71.0%
4959549 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.81 74.0 5.92e-01 100.0% 60.5%
3729011 601.1.1.90 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3433 0.81 74.0 6.03e-01 100.0% 90.9%
3582053 601.1.2.64 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_VBS2 0.81 73.0 7.18e-01 100.0% 100.0%
5065764 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.80 69.0 6.76e-01 100.0% 85.7%
3191897 601.1.1.150 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF7783 0.80 73.0 6.58e-01 100.0% 89.2%
3393033 5054.1.1.63 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, YVC1_C 0.80 73.0 4.88e-01 100.0% 31.0%
3253934 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.80 72.0 6.75e-01 100.0% 98.3%
3619001 601.1.1.57 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 0.80 73.0 6.78e-01 100.0% 90.0%
3910532 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.80 73.0 6.67e-01 100.0% 92.8%
3978380 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.79 61.0 5.32e-01 81.4% 62.1%
3729299 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 72.0 6.15e-01 100.0% 88.4%
3404169 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.79 72.0 5.49e-01 100.0% 57.7%
5052771 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 73.0 6.90e-01 100.0% 86.1%
3730903 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.79 72.0 6.18e-01 100.0% 72.7%
3927442 601.1.1.95 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › F_actin_bind 0.79 71.0 6.37e-01 100.0% 97.8%
3598986 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.79 72.0 5.85e-01 97.9% 57.6%
3249529 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.75 67.0 6.04e-01 100.0% 88.9%
4017447 3567.1.1.51 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin 0.75 69.0 5.57e-01 100.0% 86.7%
2035448 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.75 67.0 5.25e-01 100.0% 56.1%
5080472 3834.1.1.0 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.75 55.0 3.46e-01 77.3% 88.0%
3275929 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.75 58.0 5.26e-01 82.5% 81.5%
3583786 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.74 67.0 6.15e-01 100.0% 84.8%
4028957 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.74 53.0 4.46e-01 75.3% 80.0%
3647788 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.73 58.0 5.87e-01 84.5% 86.3%
3959787 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.73 65.0 6.16e-01 100.0% 82.6%
3276862 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.72 59.0 4.59e-01 89.7% 82.3%
3692530 5054.1.1.58 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › YVC1_C 0.72 65.0 4.39e-01 100.0% 35.1%
3934139 109.59.1.11 alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › TPR_IFT80_172 0.71 43.0 3.54e-01 88.7% 33.0%
3440913 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.70 54.0 4.87e-01 82.5% 80.7%
4473674 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.70 54.0 5.24e-01 83.5% 90.9%
3980912 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 62.0 5.87e-01 100.0% 91.3%
4026281 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.69 53.0 4.16e-01 80.4% 65.3%
3960905 604.10.1.4 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › CstA 0.69 48.0 4.40e-01 73.2% 93.8%
3214019 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.67 60.0 4.16e-01 100.0% 76.4%
3298709 605.1.1.141 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N 0.67 54.0 4.97e-01 87.6% 85.6%
3969776 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.66 58.0 4.98e-01 99.0% 96.9%
3177832 174.1.1.62 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27705 0.66 49.0 4.19e-01 79.4% 61.3%
3598262 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 56.0 4.58e-01 97.9% 76.4%
3262259 5050.1.1.4 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran 0.65 59.0 4.46e-01 100.0% 52.6%
3473142 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 47.0 4.14e-01 75.3% 79.3%
3377749 3843.1.1.15 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › ETR1_N 0.64 49.0 4.87e-01 78.4% 85.0%
5064940 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.56 47.0 4.01e-01 90.7% 92.5%
3417771 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.55 45.0 3.47e-01 89.7% 62.2%
3611163 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.54 46.0 3.06e-01 95.9% 49.9%
3180975 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.51 40.0 3.27e-01 84.5% 74.2%
D3 high residues 203-249
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3c57B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.87 72.0 7.18e-01 95.7% 87.8%
5fgmA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.87 77.0 6.90e-01 100.0% 73.8%
3hugA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.84 72.0 6.12e-01 100.0% 61.3%
1gdtB03 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.84 60.0 6.14e-01 78.7% 80.0%
1ku3A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.82 70.0 6.42e-01 95.7% 80.3%
4nqwA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 69.0 6.25e-01 95.7% 70.3%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.81 68.0 5.49e-01 93.6% 53.3%
6uglB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 63.0 5.94e-01 87.2% 70.7%
3t0yA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 64.0 5.94e-01 89.4% 71.7%
1a04A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 66.0 5.53e-01 91.5% 62.5%
5f64A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 63.0 5.47e-01 91.5% 66.7%
4rocA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.78 61.0 4.74e-01 87.2% 65.0%
4go1A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 65.0 6.22e-01 93.6% 83.3%
1o57A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 64.0 5.60e-01 93.6% 66.7%
2w7nA00 1.10.10.2690 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.77 65.0 5.21e-01 95.7% 47.9%
7u37A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 57.0 5.15e-01 80.9% 63.5%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.76 62.0 4.95e-01 91.5% 72.3%
3ulqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 65.0 6.09e-01 97.9% 91.4%
3dteA02 1.10.10.1030 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › IrrE, HTH domain 0.76 53.0 5.54e-01 76.6% 97.6%
1wi9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 58.0 5.45e-01 85.1% 74.1%
2a6cA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.75 53.0 4.51e-01 74.5% 47.4%
3p7nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 60.0 5.29e-01 91.5% 63.9%
4ijaA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 60.0 5.40e-01 87.2% 66.7%
2z99A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 67.0 5.42e-01 100.0% 74.7%
2isyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 58.0 4.15e-01 85.1% 33.3%
4pcqA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 62.0 6.09e-01 91.5% 88.0%
2x4hA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 62.0 4.44e-01 91.5% 45.0%
5xsoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 59.0 5.10e-01 91.5% 65.8%
2lvsA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.74 60.0 5.71e-01 91.5% 76.8%
2hr3D02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 59.0 5.34e-01 87.2% 69.4%
2o38A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.73 51.0 4.62e-01 74.5% 55.4%
4ha8A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 59.0 5.42e-01 91.5% 95.2%
3tgnB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 57.0 5.22e-01 87.2% 65.1%
1biaA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 55.0 5.09e-01 87.2% 65.6%
5f7qC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 57.0 5.02e-01 87.2% 60.0%
1c0wA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 60.0 5.14e-01 91.5% 80.8%
3onqA03 1.10.10.2840 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain 0.72 56.0 4.10e-01 87.2% 31.3%
6cc0A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 60.0 5.36e-01 97.9% 77.1%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.71 58.0 4.14e-01 93.6% 44.4%
1fi2A00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.71 51.0 3.41e-01 89.4% 18.9%
1on2A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 58.0 5.03e-01 91.5% 83.3%
5douA01 1.10.1030.10 Mainly Alpha › Orthogonal Bundle › Carbamoyl Phosphate Synthetase; Chain A, domain 4 › Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 0.70 61.0 4.17e-01 100.0% 42.1%
1u8bA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.70 51.0 4.76e-01 80.9% 65.6%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 62.0 4.74e-01 95.7% 68.3%
1l3lA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 58.0 5.34e-01 97.9% 85.7%
5z4zC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 55.0 4.58e-01 91.5% 64.8%
3pfiA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 55.0 4.83e-01 91.5% 79.5%
3cuqB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 59.0 5.21e-01 97.9% 88.4%
2d1hB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 58.0 4.64e-01 97.9% 66.3%
2da7A00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.68 57.0 4.99e-01 95.7% 69.0%
6uvuA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 56.0 4.29e-01 91.5% 55.8%
5fo5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 54.0 4.44e-01 91.5% 63.6%
8dtqA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.65 58.0 4.82e-01 100.0% 86.6%
1lliA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.64 48.0 3.93e-01 83.0% 70.8%
3bs3A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.63 52.0 4.77e-01 89.4% 98.3%
4tv7D01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 52.0 4.38e-01 100.0% 72.9%
5wxuD01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.56 45.0 2.92e-01 91.5% 60.3%
4qozB02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 48.0 3.07e-01 100.0% 79.3%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3314861 101.1.1.267 alpha arrays › HTH › HTH › Three-helical HTH › PF26138 0.90 81.0 5.90e-01 100.0% 40.0%
3972713 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.87 75.0 5.90e-01 95.7% 48.4%
3922450 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.87 63.0 6.68e-01 76.6% 90.0%
3452676 101.1.1.267 alpha arrays › HTH › HTH › Three-helical HTH › PF26138 0.87 76.0 6.05e-01 100.0% 50.5%
4510105 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.87 64.0 6.80e-01 78.7% 92.5%
5024511 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.87 64.0 6.28e-01 80.9% 74.0%
4987653 101.1.2.139 alpha arrays › HTH › HTH › winged helix domain › HTH_23 0.87 67.0 6.82e-01 89.4% 86.7%
2464007 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.86 71.0 6.39e-01 93.6% 68.2%
3943462 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.86 73.0 6.97e-01 95.7% 81.8%
4008322 101.1.1.17 alpha arrays › HTH › HTH › Three-helical HTH › HTH_7 0.85 64.0 6.08e-01 87.2% 69.1%
4683276 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.85 76.0 5.99e-01 100.0% 49.5%
3460321 101.1.1.267 alpha arrays › HTH › HTH › Three-helical HTH › PF26138 0.85 76.0 5.14e-01 100.0% 29.4%
3959252 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.85 75.0 6.95e-01 100.0% 78.3%
3640035 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.85 63.0 5.17e-01 87.2% 44.7%
5064314 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.84 66.0 6.08e-01 85.1% 66.7%
5064701 101.1.2.879 alpha arrays › HTH › HTH › winged helix domain › DUF134 0.84 73.0 6.12e-01 97.9% 58.7%
3409145 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.84 62.0 6.10e-01 83.0% 74.0%
4944862 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.84 72.0 6.08e-01 97.9% 60.0%
4978135 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.84 74.0 5.19e-01 100.0% 53.1%
3340619 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 69.0 4.30e-01 93.6% 17.3%
3988724 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 65.0 6.02e-01 85.1% 66.7%
2448404 101.1.1.31 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 0.83 72.0 6.69e-01 100.0% 81.7%
4944726 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 71.0 6.56e-01 97.9% 80.0%
4334910 101.1.1.107 alpha arrays › HTH › HTH › Three-helical HTH › DUF134 0.82 70.0 5.15e-01 97.9% 38.4%
3944309 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.82 64.0 6.37e-01 87.2% 82.0%
4979402 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.82 63.0 5.84e-01 85.1% 68.3%
4934485 101.1.1.107 alpha arrays › HTH › HTH › Three-helical HTH › DUF134 0.82 69.0 5.99e-01 97.9% 63.5%
4347676 101.1.6.4 alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C 0.82 66.0 5.38e-01 91.5% 48.9%
3913655 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.81 70.0 5.96e-01 100.0% 60.0%
4947436 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.81 69.0 6.59e-01 97.9% 85.5%
3741290 101.1.1.201 alpha arrays › HTH › HTH › Three-helical HTH › Bot1p 0.81 69.0 5.56e-01 97.9% 50.0%
3590732 101.1.1.364 alpha arrays › HTH › HTH › Three-helical HTH › HTH_49 0.81 61.0 6.28e-01 89.4% 84.4%
3971860 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.81 64.0 6.30e-01 87.2% 84.0%
3090474 4020.1.1.0 a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes 0.81 71.0 5.06e-01 100.0% 36.2%
4010691 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.81 66.0 6.30e-01 91.5% 83.6%
4993585 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.81 63.0 5.82e-01 85.1% 66.7%
4244028 101.1.1.107 alpha arrays › HTH › HTH › Three-helical HTH › DUF134 0.80 68.0 6.34e-01 97.9% 80.0%
4031535 101.1.1.275 alpha arrays › HTH › HTH › Three-helical HTH › GerE 0.80 67.0 6.19e-01 95.7% 73.3%
5023952 101.1.2.888 alpha arrays › HTH › HTH › winged helix domain › Sigma70_r4_2 0.80 65.0 5.74e-01 91.5% 62.9%
4197050 101.1.6.4 alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C 0.80 64.0 5.01e-01 91.5% 41.9%
4606780 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.80 65.0 6.02e-01 91.5% 83.3%
4943227 101.1.1.63 alpha arrays › HTH › HTH › Three-helical HTH › HTH_28 0.79 60.0 6.12e-01 91.5% 86.7%
3879118 101.1.1.60 alpha arrays › HTH › HTH › Three-helical HTH › HTH_23 0.79 61.0 5.83e-01 85.1% 72.7%
3753093 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.79 62.0 5.54e-01 89.4% 61.5%
3904156 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.79 56.0 5.77e-01 80.9% 80.0%
3544647 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.79 62.0 5.60e-01 89.4% 63.1%
5022417 101.1.3.8 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › Sigma70_r4_2 0.79 64.0 5.30e-01 91.5% 58.8%
3987867 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.79 66.0 6.53e-01 93.6% 90.0%
3967748 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.79 66.0 5.48e-01 95.7% 52.9%
3793383 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.79 64.0 5.71e-01 89.4% 92.3%
4002185 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.78 64.0 5.43e-01 89.4% 57.3%
4997129 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.78 65.0 6.46e-01 95.7% 94.0%
3509159 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.78 59.0 5.55e-01 89.4% 66.7%
4010015 101.1.6.23 alpha arrays › HTH › HTH › TrpR › PF30445 0.78 55.0 5.84e-01 83.0% 90.0%
3410877 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.78 59.0 5.23e-01 89.4% 57.1%
3284469 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.77 66.0 5.76e-01 100.0% 64.0%
4974140 101.1.2.141 alpha arrays › HTH › HTH › winged helix domain › HTH_24 0.77 58.0 4.49e-01 80.9% 40.0%
4973961 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 61.0 4.96e-01 100.0% 45.3%
4863786 101.1.1.60 alpha arrays › HTH › HTH › Three-helical HTH › HTH_23 0.77 64.0 6.12e-01 93.6% 80.0%
3590885 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.76 61.0 5.39e-01 89.4% 61.4%
3391053 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.76 56.0 5.69e-01 80.9% 84.4%
4969697 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.76 59.0 6.01e-01 87.2% 88.9%
4974224 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.75 58.0 5.44e-01 91.5% 68.3%
3404418 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.75 59.0 5.25e-01 89.4% 60.0%
3981688 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.75 61.0 5.51e-01 91.5% 76.9%
3857628 101.1.3.29 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › CENP-B_N 0.75 57.0 5.21e-01 89.4% 61.5%
3502245 101.1.6.13 alpha arrays › HTH › HTH › TrpR › HTH_28 0.75 58.0 5.93e-01 87.2% 91.1%
4194508 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.75 56.0 5.40e-01 85.1% 70.9%
3693312 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.75 61.0 5.68e-01 93.6% 80.0%
3281819 101.1.1.13 alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1 0.74 64.0 5.32e-01 95.7% 57.5%
3565285 101.1.1.24 alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N 0.73 56.0 5.14e-01 89.4% 63.1%
3947091 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.73 59.0 5.47e-01 91.5% 83.3%
4008147 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.73 58.0 5.34e-01 93.6% 78.5%
3985633 101.1.1.13 alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1 0.72 64.0 6.06e-01 100.0% 85.5%
3949663 101.1.1.307 alpha arrays › HTH › HTH › Three-helical HTH › DUF3071 0.71 53.0 5.57e-01 85.1% 95.0%
4659976 101.1.1.25 alpha arrays › HTH › HTH › Three-helical HTH › DUF433 0.71 55.0 4.03e-01 91.5% 30.1%
3374351 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.68 54.0 5.37e-01 93.6% 94.0%