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IMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003853

Arc-Vir

IMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003853

Quality

83.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-71
PDB
Domain cluster: representative
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.86 73.0 5.61e-01 94.4% 44.1%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 62.0 6.51e-01 88.7% 88.9%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.81 64.0 6.58e-01 94.4% 88.2%
4nx9A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.81 71.0 5.41e-01 95.8% 93.5%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.80 65.0 4.94e-01 88.7% 39.7%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 67.0 5.77e-01 90.1% 66.4%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.78 72.0 6.11e-01 100.0% 88.4%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 67.0 6.53e-01 93.0% 92.2%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.78 68.0 4.73e-01 94.4% 99.5%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 66.0 5.97e-01 93.0% 68.8%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 65.0 6.78e-01 88.7% 100.0%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 60.0 6.56e-01 81.7% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.77 68.0 5.84e-01 97.2% 64.5%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.77 64.0 5.38e-01 91.5% 55.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.76 66.0 4.25e-01 94.4% 64.1%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 66.0 4.41e-01 94.4% 35.5%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.76 65.0 5.45e-01 93.0% 56.4%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 52.0 5.63e-01 94.4% 85.0%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.76 60.0 4.68e-01 90.1% 40.7%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.76 67.0 5.66e-01 95.8% 98.2%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.75 68.0 5.25e-01 100.0% 88.9%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 52.0 5.62e-01 94.4% 86.4%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.75 63.0 5.61e-01 90.1% 69.4%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.74 56.0 4.77e-01 85.9% 50.0%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 68.0 5.89e-01 100.0% 91.5%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 64.0 5.51e-01 94.4% 67.0%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.74 58.0 4.56e-01 85.9% 43.1%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 60.0 5.03e-01 94.4% 53.4%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 58.0 5.31e-01 84.5% 68.1%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 61.0 5.22e-01 94.4% 59.1%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 59.0 6.07e-01 88.7% 100.0%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 62.0 4.41e-01 95.8% 34.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 59.0 5.16e-01 91.5% 70.4%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 64.0 4.94e-01 98.6% 47.7%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.72 59.0 5.02e-01 88.7% 56.6%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.72 61.0 6.13e-01 93.0% 98.6%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.72 62.0 5.09e-01 97.2% 55.0%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 64.0 5.35e-01 100.0% 94.2%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 58.0 5.17e-01 94.4% 63.4%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 58.0 5.22e-01 94.4% 63.7%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.71 58.0 6.04e-01 93.0% 98.4%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 60.0 5.32e-01 94.4% 70.6%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.71 52.0 5.48e-01 91.5% 91.8%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.70 57.0 5.72e-01 93.0% 89.0%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.70 57.0 5.47e-01 93.0% 79.0%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.70 57.0 4.40e-01 90.1% 89.4%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 58.0 4.71e-01 94.4% 48.5%
7y9hB01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.69 62.0 3.93e-01 95.8% 23.3%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.69 58.0 5.48e-01 94.4% 81.4%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 61.0 5.31e-01 100.0% 67.3%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 59.0 4.97e-01 100.0% 57.3%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.67 55.0 5.23e-01 93.0% 83.7%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 58.0 4.74e-01 95.8% 61.8%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 56.0 5.38e-01 95.8% 85.2%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.66 54.0 4.71e-01 88.7% 59.8%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 57.0 4.62e-01 100.0% 51.1%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.64 53.0 5.21e-01 93.0% 88.2%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.64 47.0 4.56e-01 95.8% 70.9%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.63 53.0 4.60e-01 93.0% 72.1%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.63 53.0 4.64e-01 95.8% 60.7%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 51.0 4.69e-01 93.0% 67.0%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 55.0 4.68e-01 100.0% 61.0%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 55.0 3.60e-01 100.0% 29.3%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3680914 3291.1.1.116 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › GIDE 0.81 67.0 6.62e-01 87.3% 84.0%
4649114 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.81 65.0 5.75e-01 90.1% 61.0%
3957632 150.5.1.53 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE 0.81 65.0 5.54e-01 94.4% 55.5%
3250955 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.80 70.0 4.54e-01 94.4% 23.9%
2075297 3559.1.1.0 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 0.80 68.0 5.68e-01 94.4% 55.5%
4947622 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.80 68.0 5.41e-01 91.5% 50.4%
3631429 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 64.0 4.91e-01 88.7% 91.3%
1291200 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.79 70.0 4.54e-01 95.8% 24.1%
3962961 150.5.1.53 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE 0.79 64.0 6.14e-01 85.9% 100.0%
3400366 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.79 69.0 5.40e-01 94.4% 49.3%
3952598 150.7.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE 0.78 69.0 6.27e-01 93.0% 73.3%
3719904 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.78 66.0 4.10e-01 94.4% 17.6%
3477880 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.78 69.0 4.48e-01 95.8% 24.5%
3788609 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 68.0 5.86e-01 95.8% 62.7%
5049284 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.78 68.0 5.68e-01 95.8% 93.3%
4946854 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.78 66.0 5.32e-01 97.2% 50.0%
4555586 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.78 72.0 6.23e-01 100.0% 92.4%
3979729 3755.3.1.500 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › IpaC_SipC 0.77 64.0 5.30e-01 97.2% 52.5%
4263341 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.77 69.0 5.76e-01 95.8% 60.9%
4147453 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.77 72.0 6.09e-01 100.0% 86.4%
3769852 7515.1.1.4 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase,Sulfatase_C 0.77 70.0 4.04e-01 100.0% 12.1%
4359654 605.2.1.3 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N 0.76 70.0 6.00e-01 100.0% 86.4%
3341646 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 67.0 4.37e-01 95.8% 94.8%
3737161 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.76 66.0 5.65e-01 95.8% 60.9%
4013672 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.76 68.0 6.01e-01 98.6% 82.0%
4175087 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.76 70.0 5.94e-01 100.0% 86.4%
3411108 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.76 67.0 5.39e-01 97.2% 51.9%
3969814 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.76 63.0 6.23e-01 95.8% 86.7%
3641422 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.75 65.0 5.57e-01 94.4% 71.8%
3405706 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.75 64.0 5.23e-01 94.4% 52.3%
5060491 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 66.0 5.46e-01 95.8% 72.5%
3691039 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.75 66.0 6.33e-01 97.2% 87.5%
3631949 309.1.2.5 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › Seryl_tRNA_N 0.74 67.0 5.53e-01 100.0% 88.8%
3577907 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.74 63.0 4.27e-01 94.4% 27.5%
3974231 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.73 61.0 6.17e-01 91.5% 98.6%
3626951 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.73 62.0 4.88e-01 94.4% 54.0%
5045310 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.73 61.0 6.13e-01 93.0% 91.4%
3489884 150.1.1.80 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Myelin_PLP 0.72 63.0 5.04e-01 97.2% 49.3%
5055564 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.72 63.0 5.20e-01 94.4% 55.8%
3938995 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.72 58.0 5.39e-01 97.2% 70.0%
3974573 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.72 62.0 5.10e-01 97.2% 56.2%
3984493 325.1.7.28 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_YBHG 0.72 61.0 4.98e-01 94.4% 98.5%
3266175 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.71 59.0 5.09e-01 94.4% 57.4%
3719886 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.71 59.0 4.83e-01 94.4% 51.1%
None 0.71 60.0 4.94e-01 94.4% 98.5%
3287601 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.70 59.0 5.44e-01 95.8% 73.4%
3694833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 61.0 4.99e-01 97.2% 56.2%
3482265 601.19.1.36 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF4455 0.70 62.0 4.55e-01 100.0% 58.9%
3950415 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.69 58.0 4.37e-01 95.8% 37.3%
4203104 3560.1.1.7 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med10 0.69 59.0 4.69e-01 95.8% 50.3%
3229593 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.69 61.0 4.58e-01 100.0% 82.3%
3953644 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.68 58.0 4.35e-01 95.8% 38.3%
3927605 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 57.0 3.80e-01 94.4% 23.0%
3885007 3922.1.1.67 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Val_tRNA-synt_C 0.68 55.0 5.58e-01 94.4% 92.9%
4013585 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.68 56.0 5.67e-01 93.0% 97.1%
3456370 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.68 57.0 4.49e-01 95.8% 44.5%
3821609 2004.1.1.442 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 0.67 56.0 3.33e-01 93.0% 15.2%
3880637 3755.3.1.465 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.66 57.0 4.60e-01 97.2% 50.0%
4046042 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.66 55.0 4.63e-01 93.0% 60.0%
3197870 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 54.0 4.50e-01 94.4% 52.6%
4180833 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.65 56.0 3.77e-01 94.4% 30.4%
4299170 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.65 53.0 5.38e-01 93.0% 95.7%
3782155 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 50.0 2.93e-01 85.9% 9.9%
3410365 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.59 50.0 3.20e-01 100.0% 18.2%
D2 medium residues 72-134
PDB
Domain cluster: representative
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 67.0 6.75e-01 87.3% 95.2%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.81 59.0 6.56e-01 85.7% 98.0%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.81 64.0 5.81e-01 88.9% 63.9%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.81 61.0 5.39e-01 85.7% 57.5%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.80 61.0 6.01e-01 81.0% 100.0%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 61.0 6.14e-01 82.5% 96.8%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.79 64.0 5.69e-01 87.3% 67.8%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 61.0 6.24e-01 88.9% 88.3%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 61.0 6.30e-01 92.1% 91.5%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.76 63.0 6.21e-01 95.2% 84.8%
2x9xA04 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 57.0 6.09e-01 93.7% 92.6%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 67.0 6.43e-01 96.8% 94.4%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.75 55.0 4.61e-01 92.1% 46.3%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.73 61.0 6.27e-01 95.2% 96.7%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.71 60.0 5.24e-01 93.7% 63.5%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 61.0 4.64e-01 100.0% 87.8%
4ikhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.71 62.0 4.88e-01 96.8% 77.2%
7zmgL01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 53.0 5.01e-01 84.1% 67.5%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 60.0 4.84e-01 100.0% 58.6%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.69 63.0 3.69e-01 100.0% 40.3%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 53.0 5.42e-01 85.7% 94.8%
4b7yD00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.69 58.0 5.02e-01 93.7% 83.5%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.69 58.0 5.90e-01 96.8% 95.1%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.67 56.0 4.99e-01 93.7% 71.4%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.67 51.0 4.22e-01 87.3% 44.2%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.67 58.0 4.42e-01 100.0% 62.8%
4cb8A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.67 58.0 3.47e-01 100.0% 19.3%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 56.0 4.60e-01 93.7% 75.2%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 57.0 5.58e-01 100.0% 89.6%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.67 55.0 4.26e-01 95.2% 45.3%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.66 51.0 4.13e-01 85.7% 71.4%
1qu3A04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.66 56.0 4.36e-01 100.0% 95.3%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 56.0 4.57e-01 96.8% 74.2%
3am6A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 55.0 3.81e-01 98.4% 61.2%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.64 49.0 4.60e-01 88.9% 66.7%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.64 49.0 4.91e-01 85.7% 86.2%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 54.0 3.94e-01 100.0% 65.7%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.63 44.0 4.32e-01 81.0% 67.6%
1kf6C00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.61 51.0 4.06e-01 93.7% 69.2%
2xvtC00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.59 46.0 4.32e-01 96.8% 69.6%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 50.0 3.88e-01 98.4% 71.8%
2l3oA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 42.0 3.43e-01 79.4% 69.4%
3nkuA00 1.10.357.170 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.57 47.0 3.57e-01 98.4% 81.2%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 48.0 3.74e-01 100.0% 73.9%
2fiyA00 3.90.1670.10 Alpha Beta › Alpha-Beta Complex › FdhE-like fold › FdhE-like domain 0.54 46.0 3.08e-01 98.4% 49.1%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 43.0 3.43e-01 100.0% 80.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5008465 174.1.1.95 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7144 0.93 74.0 5.54e-01 84.1% 37.9%
3598167 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.84 66.0 4.87e-01 84.1% 66.7%
3210486 3932.1.1.5 alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › GATA_AreA 0.82 56.0 5.23e-01 77.8% 58.7%
3593736 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.80 66.0 5.55e-01 87.3% 55.0%
3969893 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 63.0 6.26e-01 87.3% 81.5%
3837404 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 62.0 4.83e-01 84.1% 55.4%
3718969 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.78 59.0 4.27e-01 82.5% 30.3%
3318195 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.77 59.0 5.43e-01 100.0% 63.7%
2503462 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.77 68.0 5.94e-01 100.0% 64.9%
3917098 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.75 61.0 3.49e-01 85.7% 10.5%
3839889 601.51.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin 0.75 67.0 5.08e-01 98.4% 44.8%
3215014 632.22.1.184 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › SMC_N 0.75 61.0 3.57e-01 88.9% 23.4%
4646549 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.74 56.0 4.86e-01 81.0% 55.8%
5035704 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.73 58.0 4.69e-01 95.2% 45.8%
5081683 2002.3.1.3 a/b barrels › TIM beta/alpha-barrel › Glycoside hydrolase/deacetylase › Glycoside hydrolase/deacetylase › Glyco_hydro_57 0.73 55.0 3.36e-01 84.1% 14.2%
3179301 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.72 62.0 3.64e-01 95.2% 13.1%
4030051 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.71 60.0 3.62e-01 92.1% 23.3%
3683804 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.71 58.0 4.48e-01 88.9% 42.3%
5048605 5069.1.3.60 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › OST3_OST6 0.70 63.0 5.19e-01 98.4% 66.4%
3913307 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.70 63.0 5.56e-01 98.4% 70.0%
3717587 193.1.1.0 alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like 0.70 55.0 3.83e-01 85.7% 28.5%
5000147 3960.1.1.0 alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain 0.70 58.0 4.98e-01 95.2% 100.0%
4975787 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.69 63.0 4.62e-01 100.0% 91.9%
3743177 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.68 61.0 4.65e-01 100.0% 51.0%
3378189 5076.2.1.9 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › Choline_transpo 0.68 56.0 3.76e-01 95.2% 71.9%
4080245 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.67 50.0 4.61e-01 93.7% 61.2%
3645559 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.67 49.0 4.42e-01 82.5% 55.6%
3482907 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 55.0 4.52e-01 93.7% 74.8%
3595526 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 56.0 4.36e-01 98.4% 64.3%
3230168 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.63 54.0 3.52e-01 100.0% 54.2%
3963040 5069.1.1.14 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Virul_fac_BrkB 0.63 52.0 3.76e-01 96.8% 94.0%
4506363 5058.1.1.73 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF27423 0.62 56.0 5.06e-01 100.0% 90.6%
3350174 3226.1.1.2 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Sulfate_transp 0.60 49.0 3.07e-01 96.8% 41.4%
3941043 605.1.1.211 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › ATG9 0.58 43.0 2.62e-01 88.9% 10.7%
3280625 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.58 47.0 3.14e-01 98.4% 56.5%