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IMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003883
Arc-VirIMGVR_UViG_3300014913_001316-3300014913-Ga0164310_1000003883
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 95-206
Domain cluster:
representative
CATH (69)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.87 | 56.0 | 6.83e-01 | 78.6% | 98.7% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.86 | 67.0 | 5.36e-01 | 80.4% | 62.6% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.86 | 54.0 | 6.53e-01 | 73.2% | 95.9% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.83 | 64.0 | 5.16e-01 | 80.4% | 60.5% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 73.0 | 5.99e-01 | 97.3% | 96.0% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.81 | 60.0 | 6.78e-01 | 76.8% | 100.0% |
| 4lctB00 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.81 | 48.0 | 3.30e-01 | 79.5% | 19.0% |
| 4jhrB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.81 | 49.0 | 3.53e-01 | 73.2% | 23.2% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 61.0 | 6.56e-01 | 81.2% | 100.0% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.78 | 71.0 | 5.91e-01 | 100.0% | 67.5% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.77 | 68.0 | 6.84e-01 | 100.0% | 94.7% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.75 | 68.0 | 5.85e-01 | 100.0% | 76.4% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 55.0 | 4.10e-01 | 75.9% | 82.0% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 54.0 | 4.06e-01 | 74.1% | 83.6% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.75 | 68.0 | 5.81e-01 | 100.0% | 73.6% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.75 | 68.0 | 6.47e-01 | 100.0% | 85.2% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 53.0 | 4.00e-01 | 74.1% | 81.4% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 66.0 | 6.39e-01 | 98.2% | 97.6% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.73 | 54.0 | 4.13e-01 | 75.9% | 81.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.73 | 66.0 | 6.25e-01 | 97.3% | 82.7% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.73 | 54.0 | 5.36e-01 | 75.9% | 76.3% |
| 1cgnA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.73 | 66.0 | 6.42e-01 | 100.0% | 97.6% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 65.0 | 6.42e-01 | 98.2% | 98.3% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 52.0 | 3.99e-01 | 74.1% | 81.2% |
| 2a0bA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.73 | 57.0 | 5.59e-01 | 100.0% | 78.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 51.0 | 4.99e-01 | 73.2% | 76.2% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 54.0 | 4.50e-01 | 79.5% | 73.6% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 52.0 | 3.98e-01 | 75.9% | 82.3% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 63.0 | 6.06e-01 | 100.0% | 90.8% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.71 | 61.0 | 6.26e-01 | 94.6% | 99.1% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 51.0 | 4.29e-01 | 75.9% | 91.6% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.70 | 57.0 | 5.38e-01 | 87.5% | 91.9% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.70 | 50.0 | 4.91e-01 | 73.2% | 79.8% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 63.0 | 6.02e-01 | 98.2% | 84.7% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.70 | 53.0 | 3.91e-01 | 79.5% | 54.4% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.69 | 61.0 | 5.56e-01 | 99.1% | 77.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 5.85e-01 | 96.4% | 97.4% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.68 | 61.0 | 5.20e-01 | 96.4% | 87.9% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 58.0 | 5.78e-01 | 95.5% | 95.0% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 49.0 | 3.72e-01 | 75.9% | 78.9% |
| 4akvA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 49.0 | 4.08e-01 | 75.0% | 91.1% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.67 | 61.0 | 5.93e-01 | 100.0% | 91.7% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 60.0 | 5.81e-01 | 100.0% | 91.9% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 48.0 | 3.96e-01 | 75.0% | 86.1% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 59.0 | 5.77e-01 | 100.0% | 91.7% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 45.0 | 4.46e-01 | 85.7% | 67.2% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 57.0 | 5.61e-01 | 100.0% | 90.7% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 54.0 | 4.36e-01 | 92.9% | 72.4% |
| 3thxB03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.64 | 54.0 | 4.63e-01 | 100.0% | 56.5% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 55.0 | 5.23e-01 | 93.8% | 90.8% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.63 | 55.0 | 5.48e-01 | 100.0% | 92.4% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.63 | 54.0 | 5.39e-01 | 100.0% | 93.0% |
| 5tpmB00 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.63 | 51.0 | 4.74e-01 | 96.4% | 68.8% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.63 | 49.0 | 4.10e-01 | 81.2% | 94.6% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 44.0 | 3.62e-01 | 73.2% | 83.8% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 56.0 | 4.31e-01 | 100.0% | 74.3% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.62 | 54.0 | 4.02e-01 | 95.5% | 95.9% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.62 | 54.0 | 5.25e-01 | 96.4% | 87.4% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.60 | 46.0 | 4.88e-01 | 81.2% | 91.8% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.60 | 52.0 | 4.42e-01 | 100.0% | 92.6% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.59 | 52.0 | 4.70e-01 | 95.5% | 83.4% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.59 | 50.0 | 4.03e-01 | 91.1% | 51.7% |
| 3ro3A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 44.0 | 3.86e-01 | 94.6% | 55.3% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 51.0 | 3.98e-01 | 100.0% | 81.8% |
| 4u72A01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 51.0 | 4.08e-01 | 96.4% | 84.2% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 48.0 | 4.21e-01 | 90.2% | 87.5% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 50.0 | 4.87e-01 | 98.2% | 100.0% |
| 8a3tD01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 49.0 | 3.41e-01 | 98.2% | 37.6% |
| 7ep1B01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 40.0 | 3.09e-01 | 92.0% | 37.2% |
ECOD (61)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4935725 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.99 | 95.0 | 8.80e-01 | 100.0% | 82.2% |
| 4952530 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.89 | 83.0 | 7.73e-01 | 99.1% | 91.1% |
| 5082279 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.88 | 81.0 | 7.91e-01 | 100.0% | 90.8% |
| 4927629 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.87 | 82.0 | 8.02e-01 | 100.0% | 95.0% |
| 5058790 | 133.2.1.1 ↗ | alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C | 0.85 | 66.0 | 5.47e-01 | 80.4% | 62.2% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.84 | 60.0 | 5.74e-01 | 81.2% | 63.8% |
| 3290392 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.84 | 78.0 | 6.50e-01 | 100.0% | 88.6% |
| 3488077 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.83 | 62.0 | 6.73e-01 | 78.6% | 100.0% |
| 4930881 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.82 | 75.0 | 6.06e-01 | 99.1% | 96.6% |
| 3440791 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.82 | 63.0 | 6.07e-01 | 80.4% | 88.8% |
| 3534658 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.82 | 64.0 | 5.56e-01 | 81.2% | 68.8% |
| 4663621 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.81 | 63.0 | 5.95e-01 | 81.2% | 92.3% |
| 3282142 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.81 | 74.0 | 6.79e-01 | 100.0% | 82.1% |
| 3360270 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.80 | 60.0 | 5.06e-01 | 77.7% | 52.8% |
| 3613499 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.80 | 74.0 | 6.44e-01 | 100.0% | 69.7% |
| 3613749 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 62.0 | 5.23e-01 | 80.4% | 56.6% |
| 5021299 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.79 | 72.0 | 5.94e-01 | 100.0% | 72.3% |
| 4028709 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.79 | 72.0 | 5.47e-01 | 100.0% | 55.9% |
| 4987070 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.78 | 67.0 | 6.65e-01 | 92.9% | 98.3% |
| 3582458 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.78 | 56.0 | 4.06e-01 | 74.1% | 66.4% |
| 3374049 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.77 | 71.0 | 5.61e-01 | 99.1% | 89.8% |
| 3395652 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 67.0 | 6.67e-01 | 95.5% | 95.7% |
| 4320014 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.76 | 54.0 | 4.04e-01 | 74.1% | 88.5% |
| 4370662 | 601.2.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_B562 | 0.76 | 63.0 | 6.63e-01 | 92.9% | 100.0% |
| 5010536 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.75 | 68.0 | 5.68e-01 | 98.2% | 95.1% |
| 3614412 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 61.0 | 5.62e-01 | 86.6% | 88.6% |
| 3887929 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.74 | 54.0 | 5.35e-01 | 75.9% | 77.5% |
| 1251943 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.74 | 66.0 | 6.37e-01 | 98.2% | 92.0% |
| 3616476 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.74 | 54.0 | 4.31e-01 | 75.9% | 82.8% |
| 3619004 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.71 | 63.0 | 6.20e-01 | 98.2% | 95.0% |
| 4958325 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.71 | 63.0 | 5.55e-01 | 98.2% | 81.2% |
| 3251434 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 52.0 | 4.36e-01 | 75.0% | 98.9% |
| 3370265 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.71 | 61.0 | 5.86e-01 | 100.0% | 82.3% |
| 3714307 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 60.0 | 5.31e-01 | 92.0% | 79.4% |
| 4328868 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.70 | 50.0 | 3.78e-01 | 75.0% | 82.5% |
| 3880738 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.70 | 62.0 | 5.78e-01 | 100.0% | 85.0% |
| 3477880 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.70 | 50.0 | 3.66e-01 | 74.1% | 80.3% |
| 3851394 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.68 | 61.0 | 5.85e-01 | 100.0% | 88.5% |
| 4593081 | 601.1.2.139 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30710 | 0.68 | 61.0 | 5.61e-01 | 100.0% | 86.9% |
| 3508475 | 109.4.1.145 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Paf67 | 0.68 | 60.0 | 4.11e-01 | 95.5% | 88.7% |
| 4997415 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.68 | 59.0 | 5.47e-01 | 94.6% | 74.3% |
| 3711619 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.68 | 59.0 | 5.44e-01 | 98.2% | 80.0% |
| 3240810 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.68 | 58.0 | 5.44e-01 | 95.5% | 78.6% |
| 3306960 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 43.0 | 3.93e-01 | 73.2% | 49.0% |
| 3273611 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.67 | 49.0 | 3.69e-01 | 75.9% | 80.0% |
| 3701224 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.67 | 59.0 | 5.68e-01 | 95.5% | 91.2% |
| 3532355 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.66 | 47.0 | 3.49e-01 | 75.0% | 76.7% |
| 4879693 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.66 | 59.0 | 5.51e-01 | 100.0% | 91.2% |
| 3615115 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.65 | 52.0 | 4.07e-01 | 83.0% | 44.4% |
| 4146789 | 109.4.1.777 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 55.0 | 3.99e-01 | 90.2% | 36.3% |
| 3270728 | 5001.1.1.81 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom | 0.65 | 58.0 | 4.34e-01 | 99.1% | 79.3% |
| 4226243 | 109.4.1.1320 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_10, TPR_12 | 0.65 | 54.0 | 3.95e-01 | 90.2% | 36.0% |
| 3663533 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.64 | 49.0 | 4.10e-01 | 80.4% | 48.9% |
| 3207391 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.62 | 52.0 | 4.84e-01 | 92.9% | 79.3% |
| None | — | 0.61 | 49.0 | 4.00e-01 | 86.6% | 46.5% | |
| 3725616 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.61 | 55.0 | 4.89e-01 | 100.0% | 91.3% |
| 3354908 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 44.0 | 4.10e-01 | 93.8% | 58.6% |
| 5047771 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 51.0 | 5.11e-01 | 92.9% | 91.3% |
| 3735275 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 52.0 | 4.53e-01 | 100.0% | 91.7% |
| 3837424 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 53.0 | 3.83e-01 | 99.1% | 59.1% |
| 5032566 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.51 | 45.0 | 3.02e-01 | 97.3% | 45.8% |