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IMGVR_UViG_3300017482_000059-3300017482-Ga0186907_1311911

Arc-Vir

IMGVR_UViG_3300017482_000059-3300017482-Ga0186907_1311911

Quality

89.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-71
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.89 64.0 6.22e-01 74.6% 75.6%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.89 65.0 6.94e-01 76.1% 93.5%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.89 66.0 5.48e-01 77.5% 50.0%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 62.0 6.10e-01 73.2% 73.7%
1vjxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.88 69.0 5.28e-01 83.1% 77.9%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.87 67.0 5.27e-01 80.3% 76.3%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.86 64.0 4.51e-01 77.5% 48.2%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 67.0 6.67e-01 81.7% 82.2%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.85 64.0 5.11e-01 80.3% 60.4%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.84 62.0 5.69e-01 77.5% 62.6%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.84 61.0 5.50e-01 76.1% 58.9%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.84 69.0 4.94e-01 87.3% 72.2%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.84 64.0 4.87e-01 80.3% 70.2%
2gw1A02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 56.0 3.45e-01 73.2% 13.6%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.83 61.0 5.97e-01 76.1% 72.0%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.83 60.0 5.66e-01 76.1% 69.4%
2y4tA02 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.83 57.0 6.58e-01 77.5% 98.1%
6z01B03 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.82 64.0 4.85e-01 81.7% 39.0%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 65.0 5.76e-01 83.1% 62.9%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.82 60.0 5.93e-01 77.5% 88.2%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.81 63.0 5.85e-01 81.7% 77.3%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.81 63.0 4.90e-01 81.7% 41.8%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 67.0 4.41e-01 88.7% 99.3%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 62.0 5.50e-01 81.7% 66.3%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.80 59.0 5.08e-01 77.5% 52.8%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.79 62.0 5.05e-01 81.7% 47.9%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 63.0 4.44e-01 85.9% 31.1%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.78 58.0 4.70e-01 77.5% 46.8%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 60.0 4.34e-01 81.7% 53.4%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 61.0 5.55e-01 83.1% 63.4%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 60.0 4.23e-01 81.7% 71.9%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 56.0 5.66e-01 76.1% 84.7%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 68.0 5.76e-01 95.8% 72.6%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 68.0 4.87e-01 95.8% 45.8%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 56.0 4.91e-01 77.5% 69.3%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 65.0 5.06e-01 95.8% 45.8%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 63.0 4.87e-01 91.5% 42.9%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 67.0 5.15e-01 95.8% 47.9%
7zm7601 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.74 60.0 4.38e-01 84.5% 70.1%
7k3zG01 3.50.7.10 Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL 0.74 55.0 3.85e-01 78.9% 82.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.73 57.0 5.21e-01 81.7% 66.7%
2f2gA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.73 64.0 4.48e-01 95.8% 34.4%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.73 62.0 5.16e-01 91.5% 90.6%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 63.0 4.72e-01 95.8% 40.9%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 52.0 5.11e-01 77.5% 97.3%
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.71 59.0 4.13e-01 90.1% 65.3%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 62.0 4.86e-01 98.6% 46.4%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 62.0 6.03e-01 97.2% 94.9%
4o92A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 59.0 5.14e-01 93.0% 61.9%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.69 62.0 4.36e-01 100.0% 37.5%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 47.0 3.90e-01 71.8% 72.4%
2c0gA02 1.20.1150.12 Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain 0.67 54.0 4.71e-01 87.3% 86.8%
2rd3D00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.66 57.0 4.06e-01 95.8% 33.9%
3no6A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.62 54.0 3.74e-01 95.8% 31.5%
1vw4L01 3.90.1030.10 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 0.62 57.0 4.52e-01 100.0% 85.2%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.61 47.0 4.46e-01 83.1% 96.5%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.60 50.0 3.61e-01 95.8% 33.5%
2yb5F01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 44.0 4.22e-01 84.5% 96.5%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3498914 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.94 67.0 5.93e-01 73.2% 54.7%
3716015 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.92 63.0 6.80e-01 70.4% 83.3%
5003155 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.91 68.0 4.83e-01 77.5% 31.4%
5002349 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.91 68.0 7.12e-01 77.5% 87.7%
2810773 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.91 62.0 7.24e-01 73.2% 98.0%
4568335 3812.1.1.8 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › DUF5398 0.91 71.0 7.23e-01 81.7% 97.1%
3788919 2004.1.1.505 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 0.91 65.0 4.02e-01 74.6% 15.4%
4944568 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.90 65.0 6.80e-01 74.6% 84.6%
3595966 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.90 63.0 6.49e-01 73.2% 76.5%
4986977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 68.0 7.10e-01 78.9% 89.2%
3266812 3291.1.1.211 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › EMC3_TMCO1 0.89 66.0 4.91e-01 77.5% 35.6%
4165448 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.88 66.0 5.65e-01 77.5% 54.3%
5041261 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 66.0 5.16e-01 77.5% 42.2%
4570960 605.1.1.137 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › RRP36 0.88 69.0 5.12e-01 81.7% 39.4%
5048061 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.88 63.0 7.12e-01 74.6% 100.0%
4531598 4970.1.1.14 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › RRP36 0.88 69.0 5.16e-01 81.7% 40.0%
3253331 6132.1.1.0 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain 0.88 65.0 6.60e-01 77.5% 91.4%
3247204 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.88 65.0 7.04e-01 77.5% 95.0%
3685099 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.88 65.0 6.80e-01 77.5% 87.7%
4363487 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.88 66.0 5.79e-01 78.9% 57.0%
4930292 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.87 65.0 6.58e-01 77.5% 82.9%
3718848 1132.1.1.0 extended segments › Mitochondrial complex I, B16.6 subunit › Mitochondrial complex I, B16.6 subunit › Mitochondrial complex I, B16.6 subunit 0.87 63.0 5.41e-01 77.5% 50.5%
3417096 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.87 65.0 5.48e-01 77.5% 51.8%
3820373 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.87 66.0 6.02e-01 78.9% 62.2%
3962847 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.87 66.0 6.00e-01 78.9% 64.4%
5016885 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.87 59.0 6.22e-01 76.1% 76.9%
3884438 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.87 65.0 6.25e-01 78.9% 71.2%
2161989 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.86 56.0 6.75e-01 76.1% 100.0%
3385229 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.86 59.0 3.62e-01 74.6% 13.7%
3987389 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.86 68.0 3.94e-01 81.7% 11.7%
3593590 5086.1.1.20 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › NYD-SP28 0.86 61.0 4.60e-01 74.6% 34.4%
3302917 2004.1.1.505 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 0.86 62.0 3.91e-01 76.1% 16.4%
3591988 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.86 66.0 4.17e-01 81.7% 43.6%
3570403 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.85 67.0 5.39e-01 81.7% 48.0%
3956906 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.85 63.0 6.22e-01 77.5% 77.3%
4470423 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.85 64.0 5.37e-01 78.9% 50.4%
3619577 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.85 70.0 6.36e-01 85.9% 91.1%
4297392 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.85 58.0 6.78e-01 74.6% 100.0%
3922888 109.4.1.889 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M 0.85 68.0 4.70e-01 83.1% 35.6%
3766400 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.85 68.0 5.70e-01 83.1% 83.6%
3504474 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.85 69.0 6.08e-01 85.9% 90.0%
3290879 3922.1.1.155 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 0.85 66.0 6.72e-01 81.7% 85.7%
4979981 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.85 66.0 5.60e-01 81.7% 54.5%
3884649 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.84 69.0 6.17e-01 85.9% 86.3%
4345287 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.84 65.0 5.67e-01 81.7% 57.0%
3785919 109.4.1.72 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps16_C 0.84 56.0 3.93e-01 73.2% 23.9%
3976663 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.84 65.0 6.76e-01 81.7% 100.0%
3219646 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.84 61.0 6.79e-01 77.5% 98.2%
5053066 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.84 62.0 4.20e-01 77.5% 24.3%
3256857 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.84 65.0 4.12e-01 81.7% 33.7%
4060910 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.84 64.0 5.55e-01 80.3% 56.2%
3273491 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.84 64.0 4.01e-01 80.3% 16.8%
3484694 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 65.0 4.08e-01 81.7% 18.2%
4272021 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.84 65.0 5.71e-01 81.7% 58.0%
4221982 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.83 65.0 5.70e-01 81.7% 58.0%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.83 64.0 5.47e-01 81.7% 54.5%
3418094 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.83 65.0 6.26e-01 83.1% 73.8%
3690329 2004.1.1.473 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11 0.83 62.0 3.84e-01 78.9% 15.3%
1171038 3755.3.1.148 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC 0.82 64.0 4.54e-01 81.7% 31.4%
4223425 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.82 64.0 5.50e-01 81.7% 56.2%
4156333 109.4.1.206 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.82 64.0 4.93e-01 83.1% 78.0%
3744696 603.1.1.2 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Not3 0.82 68.0 5.84e-01 87.3% 63.8%
3692897 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.82 63.0 6.24e-01 81.7% 80.0%
3940815 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.81 61.0 5.14e-01 80.3% 70.4%
3497934 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.80 63.0 4.23e-01 83.1% 24.4%
3799526 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.80 62.0 3.95e-01 81.7% 58.7%
5081365 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.80 63.0 4.88e-01 83.1% 41.4%
3282043 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.80 59.0 5.52e-01 77.5% 76.5%
4042986 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.80 62.0 5.43e-01 81.7% 58.0%
3988791 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.79 57.0 5.80e-01 76.1% 78.6%
3478399 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.79 70.0 4.80e-01 95.8% 47.0%
4628639 150.1.1.59 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.79 66.0 5.96e-01 90.1% 82.1%
3369775 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.79 71.0 4.57e-01 95.8% 67.7%
4429835 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.79 60.0 5.29e-01 83.1% 57.0%
3635782 3291.1.1.53 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CENPU 0.78 60.0 4.33e-01 81.7% 31.6%
3918098 604.6.1.57 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › Not3 0.78 68.0 5.83e-01 91.5% 66.7%
5002533 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 53.0 4.59e-01 71.8% 47.6%
4446039 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.77 63.0 6.43e-01 93.0% 90.0%
5077689 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.77 68.0 5.61e-01 95.8% 68.3%
4254477 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.76 56.0 5.00e-01 77.5% 95.0%
3627942 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.73 66.0 4.82e-01 97.2% 89.1%
4999868 604.1.1.264 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Oxidored_q2 0.72 52.0 4.86e-01 76.1% 61.1%
3862608 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 54.0 4.71e-01 80.3% 60.9%
4848262 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.71 51.0 4.47e-01 76.1% 53.3%
D2 medium residues 72-155
PDB
Domain cluster: representative
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.82 71.0 6.78e-01 91.7% 89.5%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 57.0 5.98e-01 71.4% 86.8%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.81 70.0 4.99e-01 92.9% 94.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.81 70.0 6.19e-01 92.9% 82.2%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.80 69.0 6.87e-01 92.9% 93.1%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 55.0 4.82e-01 70.2% 51.7%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.80 69.0 4.88e-01 94.0% 80.4%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 71.0 6.06e-01 97.6% 88.8%
3ug9A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.80 70.0 5.04e-01 95.2% 68.4%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.79 72.0 5.26e-01 100.0% 57.5%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.79 65.0 6.43e-01 86.9% 87.4%
1u8vB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.79 67.0 4.94e-01 92.9% 46.9%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.78 66.0 5.60e-01 92.9% 83.8%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 61.0 5.22e-01 84.5% 73.5%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.76 63.0 5.13e-01 88.1% 67.5%
1yjgA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.76 67.0 5.39e-01 95.2% 65.6%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 66.0 5.88e-01 96.4% 70.8%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 62.0 5.52e-01 88.1% 72.6%
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.76 67.0 5.60e-01 98.8% 91.1%
8d3mA02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.75 63.0 4.50e-01 94.0% 31.7%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 66.0 5.46e-01 95.2% 94.4%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.75 63.0 4.72e-01 94.0% 97.2%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.75 62.0 5.82e-01 90.5% 75.0%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.75 63.0 5.08e-01 94.0% 59.4%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.74 66.0 5.85e-01 98.8% 90.8%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 60.0 5.23e-01 89.3% 66.9%
4akgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.74 65.0 5.22e-01 98.8% 79.8%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.74 61.0 5.59e-01 90.5% 70.9%
1st6A03 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.73 65.0 4.75e-01 98.8% 47.6%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.73 61.0 5.01e-01 89.3% 69.6%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.73 50.0 5.12e-01 71.4% 100.0%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.73 63.0 5.88e-01 95.2% 90.3%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 64.0 5.60e-01 94.0% 93.4%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 64.0 5.69e-01 95.2% 87.9%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.73 57.0 5.78e-01 84.5% 95.2%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.72 60.0 5.43e-01 90.5% 69.6%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.72 55.0 5.24e-01 79.8% 95.8%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 62.0 5.41e-01 95.2% 82.8%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.72 61.0 5.04e-01 91.7% 59.2%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 59.0 5.26e-01 91.7% 73.8%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 60.0 4.98e-01 92.9% 92.7%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.71 60.0 5.02e-01 94.0% 93.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.71 62.0 5.59e-01 95.2% 87.6%
2innB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.70 61.0 3.75e-01 95.2% 30.4%
1ni3A03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.70 52.0 5.12e-01 78.6% 74.7%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 63.0 5.26e-01 100.0% 81.1%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 63.0 5.76e-01 100.0% 90.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 61.0 5.34e-01 97.6% 94.4%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.68 60.0 4.65e-01 100.0% 65.4%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.68 59.0 4.67e-01 100.0% 68.5%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.68 60.0 4.87e-01 100.0% 79.6%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 57.0 4.62e-01 92.9% 88.1%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 57.0 4.67e-01 92.9% 91.3%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.67 60.0 4.92e-01 100.0% 81.0%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 56.0 4.06e-01 94.0% 57.4%
2f2gA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.66 57.0 4.23e-01 95.2% 68.8%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.66 52.0 5.29e-01 84.5% 91.5%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 54.0 4.51e-01 94.0% 93.7%
1cm5A00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.65 53.0 3.10e-01 90.5% 68.4%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.64 49.0 4.61e-01 81.0% 68.9%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 56.0 5.00e-01 100.0% 89.3%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 52.0 4.00e-01 90.5% 54.4%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.60 46.0 4.84e-01 94.0% 94.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.58 48.0 4.25e-01 89.3% 62.0%
1ng6A01 1.10.1510.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Protein Yqey; Chain: A; domain1 › Uncharacterised protein YqeY/AIM41, N-terminal domain 0.54 42.0 4.13e-01 85.7% 97.8%
ECOD (87)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3215515 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.84 69.0 6.72e-01 86.9% 86.7%
3411201 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.84 74.0 5.66e-01 95.2% 62.2%
4014519 3567.1.1.51 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin 0.83 73.0 5.51e-01 95.2% 54.2%
3510392 6157.1.1.1 alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP 0.82 73.0 6.60e-01 95.2% 92.7%
4982662 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.82 71.0 5.91e-01 92.9% 57.9%
3599922 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.82 55.0 3.54e-01 71.4% 16.6%
5018554 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 70.0 6.61e-01 92.9% 100.0%
4935575 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.81 70.0 5.76e-01 94.0% 63.3%
2549628 5001.1.1.6 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin 0.81 70.0 5.13e-01 92.9% 95.8%
3435434 632.1.1.13 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N 0.81 70.0 6.50e-01 94.0% 87.6%
3762437 601.1.2.138 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CAS_C 0.80 73.0 5.44e-01 98.8% 81.3%
3881919 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.80 71.0 5.31e-01 96.4% 80.0%
3622690 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.80 64.0 6.30e-01 84.5% 83.3%
3741398 632.1.1.8 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 0.80 69.0 5.96e-01 94.0% 69.2%
3893417 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.80 71.0 6.02e-01 96.4% 87.4%
5047177 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.80 72.0 5.14e-01 100.0% 46.1%
4393454 632.15.1.6 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 0.80 68.0 6.45e-01 92.9% 86.0%
5018556 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.80 68.0 6.16e-01 94.0% 89.6%
3940161 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.80 71.0 5.46e-01 95.2% 54.3%
4965834 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.80 64.0 6.43e-01 85.7% 95.3%
4952876 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 62.0 6.12e-01 84.5% 93.3%
4000723 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.79 70.0 5.43e-01 95.2% 54.3%
3595966 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 56.0 6.13e-01 75.0% 89.7%
3895470 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.79 62.0 5.96e-01 83.3% 77.9%
3225374 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.79 68.0 6.00e-01 94.0% 73.3%
3343869 5001.1.1.122 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 0.79 69.0 4.59e-01 95.2% 91.3%
3395441 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.78 68.0 5.43e-01 94.0% 73.8%
3804987 5001.1.1.122 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 0.78 67.0 4.47e-01 94.0% 89.4%
5026394 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.77 67.0 6.08e-01 96.4% 89.6%
2396196 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.77 67.0 5.71e-01 94.0% 68.9%
3224747 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.77 64.0 5.11e-01 91.7% 94.1%
3588296 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.76 68.0 5.84e-01 97.6% 86.9%
3862606 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.76 67.0 5.76e-01 95.2% 97.7%
3586382 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.76 66.0 6.20e-01 94.0% 93.0%
3221571 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 64.0 5.62e-01 92.9% 69.6%
3498944 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.76 67.0 5.39e-01 95.2% 58.7%
3625874 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.76 66.0 5.54e-01 92.9% 71.9%
1225266 605.4.1.1 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › Rop 0.76 66.0 6.57e-01 96.4% 96.6%
3780078 7579.1.1.66 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › HSL_N 0.75 66.0 5.54e-01 97.6% 86.2%
3833042 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.75 68.0 5.38e-01 100.0% 66.5%
3419702 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.75 64.0 5.15e-01 91.7% 52.9%
4283593 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.75 61.0 5.24e-01 89.3% 88.9%
3275693 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.74 63.0 4.73e-01 95.2% 50.2%
5077080 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.74 64.0 6.25e-01 94.0% 94.4%
4463061 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 64.0 5.76e-01 94.0% 88.7%
3741788 633.21.1.10 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.74 65.0 5.26e-01 95.2% 65.8%
3377582 632.21.1.4 alpha bundles › immunoglobulin/albumin-binding domain-like › Helical bundle domain in endo-beta-N-acetylglucosaminidase F2 › Helical bundle domain in endo-beta-N-acetylglucosaminidase F2 › GAUT_1 0.74 61.0 5.90e-01 92.9% 78.9%
3312398 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.74 63.0 5.12e-01 96.4% 67.3%
3824606 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.74 67.0 5.24e-01 100.0% 63.4%
3969699 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.73 62.0 5.19e-01 94.0% 63.4%
3728487 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 64.0 4.86e-01 95.2% 47.9%
4525096 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 62.0 4.92e-01 91.7% 66.1%
3253936 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.73 63.0 5.41e-01 96.4% 68.1%
1710694 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.72 60.0 5.43e-01 90.5% 69.6%
3239453 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.72 62.0 5.29e-01 94.0% 81.5%
3301502 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 61.0 5.05e-01 94.0% 68.7%
3429223 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.71 61.0 4.97e-01 91.7% 57.3%
3810521 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.71 59.0 5.02e-01 91.7% 75.7%
3831865 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.71 59.0 5.05e-01 89.3% 72.3%
5044422 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 63.0 5.18e-01 95.2% 96.5%
3296913 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.70 61.0 4.96e-01 97.6% 70.0%
3508614 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.70 60.0 4.99e-01 94.0% 76.6%
4945321 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.70 61.0 4.78e-01 100.0% 64.7%
3815546 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.70 62.0 5.08e-01 100.0% 72.3%
3802170 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 60.0 4.98e-01 97.6% 70.7%
3284088 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.69 61.0 5.32e-01 100.0% 82.3%
3332512 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 62.0 4.75e-01 100.0% 70.0%
3823040 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 58.0 4.62e-01 92.9% 74.1%
3611470 6004.1.1.0 extended segments › FATC domain › FATC domain › FATC domain 0.69 58.0 5.25e-01 94.0% 74.8%
4383079 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 62.0 5.07e-01 100.0% 67.1%
3408432 3636.1.1.0 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.68 57.0 4.69e-01 89.3% 62.8%
3255558 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.68 55.0 4.96e-01 88.1% 72.2%
3411948 601.1.1.43 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A 0.68 60.0 5.33e-01 97.6% 98.3%
3826910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 59.0 4.85e-01 100.0% 68.1%
3766950 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.67 59.0 4.96e-01 98.8% 75.9%
3294587 1134.1.2.2 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Archaeal C-Ala helical domain › DUF641 0.67 57.0 4.90e-01 91.7% 66.9%
4571655 150.1.1.10 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF3231 0.67 57.0 4.57e-01 92.9% 85.0%
3422917 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 59.0 4.83e-01 100.0% 67.5%
3819179 632.7.1.62 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF641 0.66 56.0 4.65e-01 90.5% 60.0%
3851394 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.66 56.0 4.90e-01 95.2% 84.6%
3253929 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 55.0 4.93e-01 92.9% 92.5%
3362472 605.1.1.132 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 0.65 55.0 5.01e-01 90.5% 76.4%
4937811 150.1.1.7 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF892 0.65 55.0 4.55e-01 96.4% 93.1%
3500075 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.65 56.0 4.99e-01 97.6% 95.0%
4014341 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.60 52.0 3.55e-01 100.0% 92.1%
3930417 7004.1.1.0 0.59 49.0 4.95e-01 94.0% 88.2%
3948847 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 41.0 3.90e-01 79.8% 74.0%