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IMGVR_UViG_3300017922_000118-3300017922-Ga0182238_10007966
Arc-VirIMGVR_UViG_3300017922_000118-3300017922-Ga0182238_10007966
Identity
- Kingdom:
- archaea
Quality
62.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 191-307_335-340
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 24.0 | 3.79e-01 | 78.0% | 85.7% |
| 3qxlA00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.59 | 46.0 | 3.69e-01 | 83.7% | 59.2% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.58 | 39.0 | 3.61e-01 | 95.1% | 53.5% |
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 36.0 | 3.32e-01 | 76.4% | 50.0% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.55 | 43.0 | 4.05e-01 | 82.1% | 82.9% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.55 | 36.0 | 3.45e-01 | 95.1% | 55.8% |
| 2k19A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.54 | 30.0 | 3.34e-01 | 88.6% | 66.3% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 36.0 | 3.50e-01 | 82.9% | 58.3% |
| 3flkA00 | 3.40.718.10 | Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase | 0.53 | 40.0 | 2.93e-01 | 80.5% | 88.6% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 46.0 | 3.93e-01 | 94.3% | 94.3% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.52 | 39.0 | 3.63e-01 | 78.9% | 83.5% |
| 2w3cA02 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.50 | 37.0 | 2.88e-01 | 77.2% | 57.0% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5049373 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.62 | 49.0 | 4.34e-01 | 84.6% | 86.7% |
| 4882899 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.59 | 39.0 | 3.68e-01 | 95.1% | 55.0% |
| 3873670 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.58 | 50.0 | 4.54e-01 | 94.3% | 92.9% |
| 3689578 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.57 | 39.0 | 3.47e-01 | 70.7% | 60.6% |
| 3697097 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 37.0 | 3.16e-01 | 84.6% | 42.1% |
| 3667064 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.55 | 43.0 | 4.24e-01 | 82.9% | 88.9% |
| 3407685 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.55 | 43.0 | 4.23e-01 | 82.9% | 76.3% |
| 3698208 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.55 | 43.0 | 4.17e-01 | 82.9% | 82.9% |
| 3313420 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.54 | 42.0 | 4.04e-01 | 82.1% | 82.1% |
| 3770770 | 601.1.2.92 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › TMEM107 | 0.53 | 41.0 | 4.15e-01 | 82.9% | 91.2% |
| 5047572 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.53 | 37.0 | 3.00e-01 | 71.5% | 39.5% |
| 4216571 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.52 | 41.0 | 4.08e-01 | 84.6% | 91.2% |
| 3211335 | 3755.4.1.30 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › TMEM107 | 0.52 | 40.0 | 4.06e-01 | 82.9% | 85.6% |
| 3436128 | 601.1.2.74 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N | 0.52 | 40.0 | 3.88e-01 | 82.9% | 90.0% |
| 3181183 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 37.0 | 3.11e-01 | 95.1% | 42.7% |
| 5047089 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 36.0 | 3.82e-01 | 95.1% | 83.6% |
| 3780807 | 174.1.1.52 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 | 0.50 | 40.0 | 3.94e-01 | 85.4% | 90.8% |
| 4342846 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.50 | 37.0 | 3.36e-01 | 77.2% | 67.9% |
D2
high
residues 358-413
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3t6pA02 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.72 | 57.0 | 5.45e-01 | 94.6% | 74.2% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.72 | 61.0 | 5.46e-01 | 98.2% | 75.3% |
| 6ygiB01 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.70 | 57.0 | 4.06e-01 | 94.6% | 32.9% |
| 1nv8B01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.69 | 55.0 | 5.14e-01 | 89.3% | 88.7% |
| 4cc9B00 | 1.20.5.4730 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 54.0 | 4.59e-01 | 91.1% | 58.2% |
| 1wj7A01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.66 | 48.0 | 4.77e-01 | 94.6% | 75.0% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.65 | 45.0 | 3.72e-01 | 76.8% | 38.9% |
| 3b0cW00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.64 | 44.0 | 4.14e-01 | 73.2% | 58.9% |
| 1gvfB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.64 | 49.0 | 3.19e-01 | 85.7% | 87.3% |
| 2jhjA02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.62 | 49.0 | 3.97e-01 | 92.9% | 55.0% |
| 1bh9B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.60 | 42.0 | 3.69e-01 | 75.0% | 47.2% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.60 | 53.0 | 5.07e-01 | 100.0% | 97.0% |
| 4ywoA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.59 | 48.0 | 3.28e-01 | 92.9% | 90.1% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 38.0 | 3.71e-01 | 73.2% | 80.0% |
| 2qyuA02 | 1.25.40.300 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein | 0.54 | 37.0 | 2.58e-01 | 71.4% | 21.0% |
| 3f4lA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.54 | 44.0 | 2.99e-01 | 92.9% | 95.5% |
| 6b8hO01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.53 | 43.0 | 3.63e-01 | 91.1% | 67.7% |
| 2zm5A02 | 1.10.20.140 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › | 0.53 | 42.0 | 3.97e-01 | 100.0% | 70.8% |
| 3hrdC02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.53 | 44.0 | 3.61e-01 | 98.2% | 71.7% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.52 | 41.0 | 3.55e-01 | 96.4% | 68.9% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 41.0 | 3.10e-01 | 87.5% | 82.7% |
| 2x65A00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.51 | 42.0 | 2.70e-01 | 96.4% | 75.7% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3638090 | 524.1.1.3 ↗ | alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGap-TBC_2 | 0.78 | 70.0 | 4.97e-01 | 100.0% | 50.6% |
| 3366426 | 4120.1.1.0 ↗ | few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP | 0.71 | 51.0 | 5.18e-01 | 76.8% | 78.2% |
| 3897972 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 58.0 | 5.18e-01 | 98.2% | 66.7% |
| 4201640 | 142.1.1.8 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › PhyR_sigma2 | 0.68 | 57.0 | 5.29e-01 | 100.0% | 86.7% |
| 1906980 | 3009.1.1.0 ↗ | alpha arrays › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like | 0.68 | 54.0 | 4.55e-01 | 92.9% | 50.5% |
| 4990528 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.67 | 56.0 | 5.02e-01 | 100.0% | 65.9% |
| 3528233 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 57.0 | 5.16e-01 | 100.0% | 69.3% |
| 3574087 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.64 | 52.0 | 4.45e-01 | 96.4% | 58.6% |
| 4927326 | 2004.1.1.196 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 | 0.63 | 43.0 | 2.97e-01 | 96.4% | 19.5% |
| 4100017 | 210.1.3.3 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 | 0.63 | 54.0 | 3.48e-01 | 100.0% | 49.5% |
| 1900588 | 144.1.1.0 ↗ | alpha arrays › PGBD-like › PGBD-like › PGBD-like | 0.61 | 48.0 | 4.27e-01 | 87.5% | 76.5% |
| 3375525 | 148.1.1.10 ↗ | alpha arrays › Histone-like › Histone-related › Histone › TAFII28 | 0.60 | 42.0 | 3.50e-01 | 76.8% | 39.1% |
| 3472797 | 277.1.1.0 ↗ | a+b two layers › PX domain › PX domain › PX domain | 0.59 | 43.0 | 3.32e-01 | 80.4% | 77.9% |
| 3473423 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.57 | 50.0 | 3.71e-01 | 100.0% | 70.3% |
| 4455041 | 3949.1.1.1 ↗ | alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT | 0.54 | 42.0 | 4.06e-01 | 100.0% | 75.4% |
| 5059837 | 2003.2.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 | 0.53 | 42.0 | 3.01e-01 | 98.2% | 93.5% |
| 3601214 | 5048.1.1.0 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like | 0.52 | 41.0 | 2.81e-01 | 94.6% | 51.5% |
| 3295850 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.50 | 37.0 | 3.87e-01 | 94.6% | 90.0% |
D3
medium
residues 1-65