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IMGVR_UViG_3300017938_000066-3300017938-Ga0187854_100036655

Arc-Vir

IMGVR_UViG_3300017938_000066-3300017938-Ga0187854_100036655

Quality

86.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 15-39_107-254_269-278
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1i74A02 3.10.310.20 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain 0.75 33.0 4.05e-01 72.7% 63.9%
7mi4A01 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.67 60.0 5.93e-01 95.6% 98.5%
8d3mI01 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.66 59.0 5.71e-01 95.6% 94.7%
3l0aA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.66 60.0 5.26e-01 97.3% 94.0%
3h4rA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.65 57.0 5.37e-01 92.3% 95.4%
3syyA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.63 54.0 5.31e-01 89.1% 91.8%
5zyuA01 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.62 52.0 5.08e-01 88.0% 100.0%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.52 21.0 3.17e-01 82.5% 90.1%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4599083 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.74 69.0 5.25e-01 97.8% 90.6%
4635416 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.74 69.0 5.18e-01 97.8% 93.1%
4072060 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.74 69.0 5.21e-01 98.9% 91.6%
4960194 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.72 68.0 5.89e-01 98.9% 98.1%
3959510 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.71 67.0 4.86e-01 99.5% 55.0%
3954713 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.71 67.0 5.90e-01 99.5% 99.6%
4958436 2008.1.1.217 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UvrD-helicase 0.70 66.0 4.00e-01 100.0% 23.7%
4536530 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.70 51.0 4.54e-01 74.3% 97.1%
4943727 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.69 63.0 5.25e-01 96.2% 88.3%
None 0.68 62.0 5.21e-01 98.4% 90.5%
None 0.68 49.0 2.89e-01 73.2% 17.1%
4403808 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.68 62.0 4.72e-01 98.4% 89.4%
5021430 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.68 64.0 6.25e-01 99.5% 97.9%
4031223 2008.1.1.204 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF2800 0.68 63.0 5.59e-01 98.4% 96.4%
4324379 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.67 62.0 4.94e-01 98.4% 88.3%
4389411 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.67 48.0 4.21e-01 73.2% 82.5%
None 0.67 61.0 4.81e-01 98.4% 87.9%
4252932 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.67 61.0 4.91e-01 98.4% 85.6%
4060254 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.66 48.0 4.28e-01 73.8% 84.0%
4928680 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.66 58.0 5.73e-01 97.8% 87.9%
4931776 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.66 53.0 5.55e-01 83.1% 100.0%
4028354 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.66 62.0 5.31e-01 100.0% 100.0%
1311130 2008.1.1.58 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3799 0.66 60.0 5.26e-01 97.3% 94.0%
5000157 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.65 61.0 5.97e-01 98.9% 91.5%
4954341 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.65 62.0 5.82e-01 100.0% 92.1%
4387318 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.65 47.0 4.26e-01 73.2% 90.6%
4346470 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.65 51.0 4.38e-01 81.4% 87.1%
3976411 2008.1.1.58 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3799 0.64 55.0 4.93e-01 91.8% 92.5%
4010258 2008.1.1.58 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3799 0.64 58.0 5.06e-01 96.7% 92.8%
3480310 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 54.0 5.05e-01 90.2% 95.1%
148043 2008.1.1.50 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ 0.63 54.0 5.35e-01 89.1% 93.2%
4497527 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.63 46.0 4.09e-01 73.2% 83.5%
5005553 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.63 58.0 5.09e-01 100.0% 98.5%
3945442 2008.1.1.50 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ 0.61 52.0 5.02e-01 89.6% 90.7%
4365754 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.61 57.0 5.54e-01 100.0% 95.1%
4927134 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.52 35.0 3.76e-01 80.9% 78.7%
3725765 2008.1.1.147 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF29557 0.51 44.0 4.29e-01 94.5% 98.5%
3693544 2008.1.1.147 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF29557 0.50 44.0 3.63e-01 95.6% 62.1%
D2 medium residues 40-106_255-268
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5kdiA00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.66 50.0 3.76e-01 82.7% 47.4%
2chrA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.66 45.0 3.91e-01 71.6% 48.0%
2lvfA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.62 42.0 3.80e-01 71.6% 64.9%
2lpnA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.61 42.0 3.90e-01 71.6% 66.7%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.61 44.0 3.59e-01 76.5% 61.7%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.60 43.0 3.69e-01 75.3% 83.7%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.60 48.0 3.66e-01 88.9% 70.4%
2dt5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 4.31e-01 76.5% 90.4%
5ab0C04 1.25.50.20 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › 0.57 43.0 2.89e-01 80.2% 66.3%
3gwqA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.57 38.0 2.79e-01 70.4% 24.0%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 40.0 3.08e-01 79.0% 77.2%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.55 38.0 3.87e-01 71.6% 85.7%
4dtdA02 1.10.3680.20 Mainly Alpha › Orthogonal Bundle › TerB-like › Actin cross-linking domain 0.54 44.0 3.72e-01 90.1% 59.9%
1rz4A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 38.0 3.67e-01 75.3% 68.5%
1wjtA00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.52 37.0 3.41e-01 74.1% 58.3%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5005257 2.21.1.0 beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.71 54.0 4.20e-01 80.2% 86.5%
5056974 2008.1.1.159 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Csa1 0.69 60.0 4.02e-01 100.0% 77.6%
3943035 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.68 46.0 5.04e-01 70.4% 100.0%
3727621 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.67 50.0 5.11e-01 80.2% 87.5%
3222767 109.12.1.2 alpha superhelices › Repetitive alpha hairpins › C-terminal domain of Ku80 › C-terminal domain of Ku80 › Ku_PK_bind 0.67 47.0 3.92e-01 72.8% 51.9%
5026427 7000.1.1.0 alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.66 48.0 4.57e-01 76.5% 98.9%
4023609 101.1.1.28 alpha arrays › HTH › HTH › Three-helical HTH › SWIRM 0.66 48.0 4.60e-01 77.8% 87.4%
5026919 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.65 46.0 4.80e-01 76.5% 100.0%
4252854 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.65 44.0 4.60e-01 71.6% 84.0%
4033104 604.15.1.0 alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.63 43.0 4.76e-01 76.5% 87.7%
4565831 3228.1.1.2 a+b two layers › Baseplate structural protein gp6 C-terminal domain III › Baseplate structural protein gp6 C-terminal domain III › Baseplate structural protein gp6 C-terminal domain III › Baseplate_J_C 0.63 44.0 4.34e-01 75.3% 74.4%
3616203 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 43.0 4.15e-01 74.1% 78.9%
2766590 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.61 42.0 4.02e-01 71.6% 73.5%
4680947 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.58 41.0 3.93e-01 74.1% 86.3%
4413129 2004.1.1.342 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_10 0.58 41.0 2.64e-01 74.1% 16.3%
3740842 604.12.1.9 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 0.58 40.0 3.73e-01 70.4% 77.0%
4617287 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.57 39.0 3.84e-01 72.8% 88.9%
None 0.55 37.0 3.81e-01 70.4% 91.3%
4974535 6102.1.1.1 alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA 0.55 39.0 3.38e-01 77.8% 80.0%
3597482 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 40.0 3.68e-01 77.8% 93.3%
3966784 4033.1.1.1 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.53 38.0 3.44e-01 75.3% 73.9%
1873797 109.4.1.41 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Lipoprotein_11 0.53 34.0 3.40e-01 71.6% 62.1%
3462217 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 38.0 3.69e-01 76.5% 93.3%
3481034 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.52 36.0 3.67e-01 71.6% 92.5%
D3 medium residues 279-325
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xa3A01 3.40.50.10540 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Crotonobetainyl-coa:carnitine coa-transferase; domain 1 0.74 54.0 3.30e-01 78.7% 18.5%
1uyjA01 3.30.360.60 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › 0.72 46.0 3.86e-01 72.3% 37.8%
3u6uC00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.70 57.0 3.56e-01 93.6% 31.6%
1hbxA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.69 58.0 4.99e-01 91.5% 64.8%
4jz8B00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.69 59.0 3.57e-01 95.7% 36.7%
4ad9A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 48.0 3.97e-01 72.3% 81.0%
2uvaG11 6.10.60.10 Special › Helix non-globular › Hydrophobic Seed Protein › 0.68 40.0 3.82e-01 74.5% 49.1%
1xttB00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.68 50.0 3.29e-01 80.9% 48.1%
1c7uA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.68 49.0 4.56e-01 80.9% 96.8%
1bd3A00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.68 48.0 3.10e-01 76.6% 32.6%
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.65 46.0 3.46e-01 74.5% 79.6%
1h2iA01 3.30.390.80 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › DNA repair protein Rad52/59/22 0.65 52.0 3.66e-01 89.4% 30.4%
3uoxB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.63 50.0 3.13e-01 93.6% 81.4%
3cuqA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 40.0 3.37e-01 70.2% 38.7%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.63 52.0 3.37e-01 95.7% 23.6%
1t6aA02 3.30.310.120 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein 0.62 43.0 3.62e-01 83.0% 42.3%
3tm4A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.61 43.0 2.89e-01 76.6% 37.0%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 43.0 3.14e-01 76.6% 57.3%
1oyiA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 38.0 3.45e-01 76.6% 48.4%
1qlmA01 3.10.340.11 Alpha Beta › Roll › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 1 › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 1 0.58 42.0 3.24e-01 78.7% 96.6%
6ketA01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.58 48.0 2.89e-01 93.6% 18.8%
3eyyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 37.0 3.12e-01 70.2% 36.6%
3l50A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.58 42.0 3.09e-01 80.9% 31.6%
2xubA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 38.0 3.30e-01 72.3% 98.7%
3icyA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 39.0 2.96e-01 74.5% 36.4%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 3.71e-01 89.4% 61.4%
4e80C01 1.10.1410.10 Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › 0.56 48.0 3.08e-01 95.7% 77.2%
4ha8A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 36.0 3.31e-01 74.5% 50.8%
5xc5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 38.0 2.70e-01 76.6% 47.3%
2mzwA01 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.54 38.0 3.32e-01 76.6% 48.7%
1yx1A00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.54 37.0 2.39e-01 74.5% 31.2%
6ui4A01 1.20.120.720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain 0.52 45.0 3.72e-01 100.0% 79.5%
2jkgA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.50 34.0 2.47e-01 74.5% 46.1%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3974474 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 60.0 4.68e-01 70.2% 38.9%
3304324 101.1.2.106 alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 0.82 56.0 3.89e-01 70.2% 31.9%
4965179 5040.1.1.0 extended segments › Cytochrome c oxidase subunit II-like, transmembrane region › Cytochrome c oxidase subunit II-like, transmembrane region › Cytochrome c oxidase subunit II-like, transmembrane region 0.82 55.0 4.63e-01 70.2% 44.0%
4002132 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.80 64.0 3.83e-01 87.2% 70.5%
3923920 148.1.1.8 alpha arrays › Histone-like › Histone-related › Histone › TFIID_30kDa 0.77 57.0 4.37e-01 78.7% 61.0%
4936900 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.77 65.0 3.59e-01 91.5% 20.0%
3474795 223.2.1.34 a+b three layers › Profilin-like › profilin-like › profilin-like › NPR2 0.73 56.0 3.68e-01 83.0% 36.8%
3620102 5067.1.1.3 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched 0.71 63.0 3.40e-01 97.9% 17.5%
4033997 4070.1.1.3 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › DUF3267 0.69 59.0 4.12e-01 97.9% 76.1%
3735991 109.4.1.526 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Atx10homo_assoc 0.68 61.0 3.37e-01 100.0% 17.6%
4022855 304.117.1.5 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › PF28298 0.68 53.0 4.41e-01 91.5% 48.2%
3273185 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.68 58.0 3.32e-01 100.0% 39.5%
5073398 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.67 45.0 3.17e-01 70.2% 82.7%
3783794 192.15.1.77 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › OST3_OST6 0.67 59.0 4.32e-01 100.0% 39.2%
4620061 4043.1.1.1 a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 0.67 54.0 4.09e-01 91.5% 55.7%
3429600 101.21.1.1 alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › TP6A_N 0.66 53.0 4.07e-01 100.0% 35.4%
3740646 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.66 46.0 3.93e-01 95.7% 43.8%
3519143 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.65 57.0 3.47e-01 100.0% 27.2%
3213954 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.65 51.0 3.49e-01 91.5% 98.4%
3879800 601.3.1.8 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › IQUB 0.65 45.0 3.21e-01 80.9% 25.0%
5056085 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.65 54.0 3.63e-01 100.0% 44.4%
4033043 616.1.1.41 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Terminase_4 0.64 55.0 4.45e-01 95.7% 57.8%
4029394 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.64 49.0 3.39e-01 91.5% 98.5%
3593943 314.1.1.0 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.64 53.0 3.02e-01 93.6% 38.4%
5001357 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 49.0 3.92e-01 100.0% 41.0%
3687407 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.63 39.0 3.39e-01 76.6% 40.0%
3721713 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 39.0 3.39e-01 100.0% 41.4%
4240628 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.63 52.0 3.44e-01 100.0% 72.7%
2966548 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.63 48.0 3.38e-01 93.6% 78.7%
3587282 142.1.1.10 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › HTH_16 0.62 42.0 3.70e-01 70.2% 48.6%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.62 47.0 3.56e-01 85.1% 94.2%
4934155 101.21.1.1 alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › TP6A_N 0.62 48.0 3.72e-01 93.6% 46.7%
4328184 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.61 51.0 3.41e-01 97.9% 69.8%
3292448 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.61 49.0 3.35e-01 100.0% 69.8%
4045825 1166.1.1.1 alpha arrays › Potassium-transporting ATPase KdpC subunit › Potassium-transporting ATPase KdpC subunit › Potassium-transporting ATPase KdpC subunit › KdpC 0.61 49.0 3.35e-01 91.5% 65.6%
3277822 4018.1.1.2 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P 0.61 50.0 3.68e-01 100.0% 63.4%
3441807 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.61 42.0 3.51e-01 87.2% 38.8%
1688953 6154.1.1.1 a+b complex topology › C-terminal domain of Ebola nucleoprotein › C-terminal domain of Ebola nucleoprotein › C-terminal domain of Ebola nucleoprotein › Ebola_NP 0.61 43.0 3.36e-01 74.5% 51.5%
4182876 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.60 50.0 3.34e-01 100.0% 82.4%
3624164 331.23.1.8 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › Gemin6_C 0.60 45.0 3.89e-01 78.7% 77.1%
3608575 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.60 45.0 3.35e-01 80.9% 67.5%
5054414 101.21.1.1 alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › TP6A_N 0.60 47.0 3.68e-01 97.9% 44.0%
4441223 4018.1.1.2 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P 0.60 53.0 3.73e-01 100.0% 61.3%
4013126 2485.1.1.1 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin 0.60 45.0 3.71e-01 83.0% 72.2%
3931057 558.1.1.0 alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain 0.60 42.0 3.90e-01 74.5% 93.3%
4977640 7592.1.1.0 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains 0.59 36.0 2.66e-01 74.5% 21.7%
3699192 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.58 48.0 3.03e-01 97.9% 42.3%
5042330 4203.1.1.0 few secondary structure elements › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 redox switch-like 0.58 43.0 3.81e-01 80.9% 75.7%
3827882 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.58 49.0 2.90e-01 91.5% 30.4%
4057677 3001.1.1.1 alpha arrays › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › THDPS_N_2 0.58 43.0 3.56e-01 80.9% 48.2%
5064344 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.57 50.0 3.53e-01 100.0% 63.2%
3574741 3006.1.1.2 a+b two layers › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › Gemin6_C 0.57 38.0 3.43e-01 70.2% 80.0%
4493573 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.57 47.0 3.18e-01 95.7% 55.0%
3261151 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 45.0 2.75e-01 85.1% 21.7%
3952539 7581.1.1.1 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N 0.56 47.0 2.89e-01 93.6% 29.8%
7688 808.1.1.2 a+b duplicates or obligate multimers › Arterivirus nucleocapsid protein › Arterivirus nucleocapsid protein › Arterivirus nucleocapsid protein › Arteri_nucleo 0.56 39.0 3.71e-01 89.4% 61.4%
4179803 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.56 45.0 3.12e-01 100.0% 79.5%
4945161 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.56 45.0 3.09e-01 97.9% 58.4%
3981752 829.1.1.1 a+b duplicates or obligate multimers › NinB › NinB › NinB › NinB 0.55 43.0 3.18e-01 85.1% 44.6%
3197266 164.1.1.0 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II 0.54 42.0 3.72e-01 85.1% 100.0%
3686916 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.53 43.0 2.75e-01 85.1% 24.7%
3487912 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 41.0 3.13e-01 87.2% 74.5%
3440366 101.1.2.106 alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 0.51 34.0 2.97e-01 83.0% 40.0%
D4 medium residues 340-415
PDB
Domain cluster: representative
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4379241 375.1.1.8 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › HypA 0.61 33.0 4.18e-01 86.8% 100.0%
5056549 375.1.1.204 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › PolC_DP2_central 0.57 38.0 3.37e-01 80.3% 47.3%
4194349 375.1.1.8 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › HypA 0.57 31.0 3.89e-01 84.2% 100.0%
4116298 375.10.1.0 few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha 0.54 46.0 3.82e-01 93.4% 56.9%
4274063 375.10.1.2 few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha › zf-DPOE 0.53 48.0 4.11e-01 100.0% 67.5%
4221969 375.10.1.1 few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha › zf-DNA_Pol 0.53 43.0 3.77e-01 86.8% 89.1%
4071570 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.52 45.0 3.72e-01 93.4% 56.9%