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IMGVR_UViG_3300017962_005066-3300017962-Ga0181581_100175979
Arc-VirIMGVR_UViG_3300017962_005066-3300017962-Ga0181581_100175979
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-70
Domain cluster:
representative
CATH (61)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5kolD00 | 3.90.950.20 | Alpha Beta › Alpha-Beta Complex › Maf protein › CinA-like | 0.78 | 69.0 | 4.99e-01 | 96.9% | 77.3% |
| 4uuwA03 | 3.90.950.20 | Alpha Beta › Alpha-Beta Complex › Maf protein › CinA-like | 0.72 | 59.0 | 4.49e-01 | 89.1% | 87.1% |
| 2aehA03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.70 | 49.0 | 4.14e-01 | 76.6% | 43.2% |
| 1imuA00 | 3.30.160.100 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like | 0.69 | 61.0 | 5.15e-01 | 100.0% | 78.5% |
| 6jb7A01 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.68 | 60.0 | 4.51e-01 | 100.0% | 80.9% |
| 4bs9A05 | 3.30.160.660 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.68 | 58.0 | 4.88e-01 | 98.4% | 72.8% |
| 2ywqA00 | 3.30.160.100 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like | 0.68 | 58.0 | 5.31e-01 | 98.4% | 94.3% |
| 1e8cA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.67 | 56.0 | 3.79e-01 | 93.8% | 27.3% |
| 2rqlA00 | 3.30.160.100 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like | 0.67 | 58.0 | 5.13e-01 | 100.0% | 89.5% |
| 1w96C04 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.67 | 58.0 | 3.87e-01 | 98.4% | 85.5% |
| 1oxxK02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.67 | 43.0 | 4.88e-01 | 82.8% | 93.3% |
| 4qdiA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.66 | 52.0 | 3.60e-01 | 93.8% | 24.9% |
| 3ulbA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.66 | 45.0 | 4.12e-01 | 70.3% | 79.5% |
| 5umsA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.65 | 46.0 | 3.99e-01 | 76.6% | 47.1% |
| 2rs7A01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.65 | 52.0 | 5.04e-01 | 90.6% | 91.9% |
| 3u12A00 | 2.30.29.180 | Mainly Beta › Roll › PH-domain like › Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain | 0.65 | 44.0 | 3.81e-01 | 81.2% | 44.2% |
| 1ah5A03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.64 | 55.0 | 5.06e-01 | 100.0% | 87.2% |
| 7oufB01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.64 | 50.0 | 3.95e-01 | 90.6% | 100.0% |
| 2awnC03 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.64 | 43.0 | 4.51e-01 | 78.1% | 77.6% |
| 2dixA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.64 | 54.0 | 5.08e-01 | 95.3% | 87.2% |
| 1whqA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.64 | 52.0 | 5.11e-01 | 93.8% | 93.0% |
| 8a7dC01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.63 | 54.0 | 3.80e-01 | 100.0% | 43.1% |
| 3k44B00 | 3.30.2450.30 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › | 0.62 | 50.0 | 3.92e-01 | 89.1% | 82.9% |
| 3dcxA00 | 2.30.29.50 | Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain | 0.62 | 44.0 | 3.67e-01 | 76.6% | 41.9% |
| 5xogK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.62 | 44.0 | 3.68e-01 | 75.0% | 68.1% |
| 1z87A01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.62 | 45.0 | 3.93e-01 | 82.8% | 50.0% |
| 6gmhK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.62 | 44.0 | 3.65e-01 | 75.0% | 67.0% |
| 3zl8A02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.62 | 53.0 | 3.60e-01 | 95.3% | 33.6% |
| 1dz1A00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.61 | 38.0 | 3.70e-01 | 75.0% | 55.7% |
| 2nugB02 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.61 | 49.0 | 4.81e-01 | 92.2% | 95.8% |
| 1g29102 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.61 | 39.0 | 4.41e-01 | 76.6% | 93.3% |
| 7t8tA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 48.0 | 3.80e-01 | 87.5% | 51.9% |
| 5j3tA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 47.0 | 3.83e-01 | 87.5% | 65.9% |
| 3kyeA00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.59 | 49.0 | 4.12e-01 | 96.9% | 54.6% |
| 1h10A00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 41.0 | 3.50e-01 | 78.1% | 41.9% |
| 6aikB00 | 3.40.50.10300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like | 0.59 | 52.0 | 3.34e-01 | 100.0% | 87.0% |
| 7yh1A01 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.59 | 47.0 | 3.94e-01 | 90.6% | 55.3% |
| 3o2zP00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.58 | 43.0 | 3.63e-01 | 81.2% | 67.2% |
| 1khiA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.58 | 45.0 | 4.33e-01 | 85.9% | 81.3% |
| 2giaA00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.58 | 47.0 | 3.65e-01 | 93.8% | 70.8% |
| 3htyA00 | 2.40.128.280 | Mainly Beta › Beta Barrel › Lipocalin › | 0.57 | 42.0 | 3.81e-01 | 82.8% | 61.7% |
| 2rovA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.56 | 42.0 | 3.58e-01 | 84.4% | 51.3% |
| 2r15A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 44.0 | 3.78e-01 | 90.6% | 66.7% |
| 2nykA01 | 3.30.500.30 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.55 | 39.0 | 3.04e-01 | 76.6% | 75.0% |
| 4cy8A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.54 | 45.0 | 3.13e-01 | 98.4% | 83.4% |
| 5lddC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 45.0 | 3.41e-01 | 96.9% | 94.0% |
| 1j0wB00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.54 | 40.0 | 3.45e-01 | 79.7% | 91.3% |
| 2lg1A02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.54 | 42.0 | 3.56e-01 | 89.1% | 52.2% |
| 1yqfB00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.53 | 42.0 | 3.13e-01 | 87.5% | 55.4% |
| 2k50A01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.53 | 41.0 | 3.62e-01 | 89.1% | 79.8% |
| 2z0qA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.53 | 41.0 | 3.33e-01 | 85.9% | 47.7% |
| 1e2tA03 | 2.40.128.150 | Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases | 0.53 | 45.0 | 3.74e-01 | 96.9% | 72.6% |
| 2hjjA00 | 3.30.160.130 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › ykff protein like domains | 0.53 | 39.0 | 3.96e-01 | 92.2% | 83.3% |
| 2cqaA01 | 2.40.50.360 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RuvBL1 DNA/RNA binding domain | 0.53 | 41.0 | 4.01e-01 | 89.1% | 90.5% |
| 1ko2A00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.53 | 43.0 | 3.03e-01 | 95.3% | 50.4% |
| 1ywuA00 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.52 | 42.0 | 3.45e-01 | 90.6% | 70.4% |
| 1azpA00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.52 | 31.0 | 3.15e-01 | 70.3% | 56.1% |
| 1i99I02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.51 | 41.0 | 3.47e-01 | 92.2% | 69.2% |
| 3gueB01 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.51 | 36.0 | 2.29e-01 | 75.0% | 84.5% |
| 4dy0B02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.51 | 41.0 | 3.40e-01 | 93.8% | 65.6% |
| 1uebA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.50 | 39.0 | 3.97e-01 | 87.5% | 90.5% |
ECOD (88)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3928306 | 223.2.1.1 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Profilin | 0.72 | 56.0 | 4.47e-01 | 100.0% | 40.3% |
| 3702442 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.71 | 61.0 | 5.25e-01 | 95.3% | 84.0% |
| 3934739 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.70 | 57.0 | 4.90e-01 | 89.1% | 59.0% |
| 3846404 | 220.1.1.61 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C_FAK1 | 0.70 | 49.0 | 3.78e-01 | 78.1% | 32.0% |
| 4932637 | 330.2.1.0 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) | 0.70 | 58.0 | 5.20e-01 | 92.2% | 93.3% |
| 4056032 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.69 | 55.0 | 3.87e-01 | 95.3% | 26.4% |
| 4937410 | 330.2.1.0 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) | 0.69 | 60.0 | 5.28e-01 | 98.4% | 95.8% |
| 3497120 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.69 | 58.0 | 5.14e-01 | 95.3% | 75.8% |
| 4157358 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.68 | 59.0 | 5.60e-01 | 100.0% | 94.9% |
| 5024203 | 330.10.1.0 ↗ | a+b two layers › dsRBD-like › Heterocyclase TruD C-terminal domain › Heterocyclase TruD C-terminal domain | 0.67 | 57.0 | 5.11e-01 | 95.3% | 72.2% |
| 5024241 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.67 | 57.0 | 5.02e-01 | 95.3% | 94.7% |
| 4968392 | 330.2.1.0 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) | 0.67 | 59.0 | 5.10e-01 | 100.0% | 92.0% |
| 4034138 | 7520.1.1.0 ↗ | a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like | 0.67 | 58.0 | 4.59e-01 | 98.4% | 82.0% |
| 3584575 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.67 | 51.0 | 3.72e-01 | 87.5% | 30.6% |
| 4040973 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.66 | 56.0 | 5.50e-01 | 96.9% | 98.6% |
| 3655368 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.66 | 56.0 | 5.33e-01 | 95.3% | 92.0% |
| 3574563 | 220.1.1.61 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C_FAK1 | 0.66 | 50.0 | 4.07e-01 | 82.8% | 43.3% |
| 3436093 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.66 | 55.0 | 5.29e-01 | 95.3% | 92.0% |
| 4638787 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.66 | 57.0 | 5.34e-01 | 100.0% | 93.8% |
| 4027723 | 252.2.1.0 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like | 0.65 | 53.0 | 5.17e-01 | 90.6% | 91.4% |
| 4026643 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.65 | 53.0 | 4.86e-01 | 90.6% | 77.6% |
| 4028464 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 44.0 | 2.83e-01 | 70.3% | 15.6% |
| 135359 | 220.1.1.17 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_1 | 0.65 | 47.0 | 3.77e-01 | 76.6% | 39.2% |
| 3961321 | 223.3.1.2 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Peptidase_S11 | 0.65 | 56.0 | 4.75e-01 | 100.0% | 63.6% |
| 5023443 | 330.4.1.0 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0.65 | 53.0 | 5.29e-01 | 90.6% | 100.0% |
| 3677438 | 4099.1.1.0 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like | 0.65 | 55.0 | 4.13e-01 | 100.0% | 60.6% |
| 5066760 | 330.6.1.1 ↗ | a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer | 0.65 | 56.0 | 4.56e-01 | 98.4% | 63.7% |
| 4054729 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.64 | 54.0 | 5.18e-01 | 96.9% | 97.3% |
| 4018116 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.64 | 56.0 | 4.64e-01 | 100.0% | 54.2% |
| 4138663 | 4099.1.1.3 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Spc24 | 0.64 | 52.0 | 5.27e-01 | 90.6% | 92.3% |
| 3626302 | 10.1.1.35 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_3 | 0.64 | 55.0 | 3.80e-01 | 98.4% | 41.8% |
| 3660311 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.63 | 50.0 | 4.74e-01 | 90.6% | 86.3% |
| 4090939 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.63 | 53.0 | 5.02e-01 | 98.4% | 88.7% |
| 4216680 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.63 | 54.0 | 4.86e-01 | 98.4% | 79.6% |
| 3935486 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.63 | 46.0 | 3.73e-01 | 87.5% | 40.0% |
| 3479661 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.63 | 53.0 | 4.45e-01 | 93.8% | 60.9% |
| 3413648 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.63 | 49.0 | 3.76e-01 | 87.5% | 37.2% |
| 160497 | 2.4.1.1 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE | 0.63 | 41.0 | 4.01e-01 | 78.1% | 60.6% |
| 3506540 | 220.1.1.20 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH | 0.62 | 48.0 | 3.97e-01 | 89.1% | 46.1% |
| 3925738 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.62 | 52.0 | 4.41e-01 | 93.8% | 60.9% |
| 3390004 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.62 | 48.0 | 4.10e-01 | 85.9% | 50.0% |
| 4608418 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.62 | 49.0 | 4.55e-01 | 90.6% | 81.2% |
| 4967370 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.61 | 51.0 | 4.69e-01 | 98.4% | 83.3% |
| 3788003 | 220.1.1.112 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_10 | 0.61 | 43.0 | 3.31e-01 | 76.6% | 32.4% |
| 3371229 | 241.1.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone | 0.61 | 51.0 | 3.61e-01 | 100.0% | 44.1% |
| 3283795 | 220.1.1.17 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_1 | 0.61 | 44.0 | 3.67e-01 | 76.6% | 42.6% |
| 3935131 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.61 | 47.0 | 3.59e-01 | 87.5% | 86.7% |
| 3801624 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.61 | 50.0 | 4.41e-01 | 95.3% | 72.0% |
| 3939670 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.60 | 46.0 | 3.47e-01 | 87.5% | 81.7% |
| 3216768 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.60 | 49.0 | 4.25e-01 | 93.8% | 65.7% |
| 3798262 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.60 | 45.0 | 3.39e-01 | 85.9% | 34.0% |
| 3885625 | 220.1.1.66 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH | 0.60 | 48.0 | 3.55e-01 | 85.9% | 44.5% |
| 3937948 | 220.1.1.47 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 | 0.59 | 45.0 | 3.33e-01 | 85.9% | 32.9% |
| 4025081 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 40.0 | 3.12e-01 | 70.3% | 34.0% |
| 3887822 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 44.0 | 3.47e-01 | 85.9% | 40.0% |
| 3723171 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 48.0 | 3.61e-01 | 87.5% | 37.3% |
| 4950038 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 48.0 | 4.60e-01 | 98.4% | 82.5% |
| 3648118 | 3270.1.1.0 ↗ | a+b two layers › a+b domain in heme oxygenase › a+b domain in heme oxygenase › a+b domain in heme oxygenase | 0.58 | 51.0 | 4.55e-01 | 98.4% | 90.0% |
| 4030625 | 219.1.1.97 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › CEPT76_peptidase | 0.58 | 49.0 | 3.33e-01 | 93.8% | 31.7% |
| 3201410 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 47.0 | 3.58e-01 | 87.5% | 38.6% |
| 3918879 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 43.0 | 3.26e-01 | 87.5% | 34.0% |
| 3255028 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.58 | 41.0 | 3.10e-01 | 76.6% | 30.6% |
| 3493061 | 883.1.1.7 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › MMM1 | 0.58 | 39.0 | 2.83e-01 | 70.3% | 39.5% |
| 4975949 | 2003.1.2.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 | 0.58 | 51.0 | 3.45e-01 | 100.0% | 71.6% |
| 3337228 | 109.3.1.186 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_5 | 0.57 | 40.0 | 2.73e-01 | 76.6% | 19.2% |
| 3582821 | 220.1.1.5 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PID | 0.57 | 43.0 | 3.88e-01 | 87.5% | 57.8% |
| 3929548 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.57 | 42.0 | 3.36e-01 | 81.2% | 65.5% |
| 3583959 | 220.1.1.23 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ICAP-1_inte_bdg | 0.57 | 45.0 | 3.49e-01 | 87.5% | 72.9% |
| 3386971 | 3675.1.1.0 ↗ | a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain | 0.57 | 33.0 | 2.67e-01 | 84.4% | 28.5% |
| 3796176 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.57 | 44.0 | 3.43e-01 | 87.5% | 61.3% |
| 1758788 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.56 | 45.0 | 3.67e-01 | 89.1% | 61.8% |
| 3591998 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.56 | 44.0 | 3.73e-01 | 87.5% | 77.3% |
| 3414887 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.56 | 47.0 | 3.19e-01 | 100.0% | 64.7% |
| 3742045 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.56 | 40.0 | 3.32e-01 | 81.2% | 39.2% |
| 3571833 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 44.0 | 3.64e-01 | 89.1% | 64.2% |
| 3398400 | 220.1.1.7 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › IRS | 0.55 | 42.0 | 3.39e-01 | 81.2% | 82.5% |
| 3919705 | 220.1.1.47 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 | 0.55 | 43.0 | 2.60e-01 | 87.5% | 11.7% |
| 4618633 | 4.26.1.1 ↗ | beta barrels › SH3 › Chromatin protein Cren7 › Chromatin protein Cren7 › Cren7 | 0.55 | 37.0 | 3.86e-01 | 70.3% | 94.9% |
| 3623096 | 883.1.1.18 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › PF26545 | 0.55 | 41.0 | 2.99e-01 | 85.9% | 70.2% |
| 3911245 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 36.0 | 3.16e-01 | 70.3% | 41.8% |
| 3269121 | 220.1.1.20 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH | 0.54 | 42.0 | 3.55e-01 | 87.5% | 49.1% |
| 4145919 | 101.1.8.4 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Flp_C | 0.53 | 40.0 | 3.07e-01 | 81.2% | 51.6% |
| 3271779 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.53 | 37.0 | 3.01e-01 | 76.6% | 35.2% |
| 3565552 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.53 | 43.0 | 3.54e-01 | 90.6% | 52.0% |
| 3741657 | 220.1.1.11 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rpn13_ADRM1_Pru | 0.53 | 41.0 | 3.48e-01 | 87.5% | 78.3% |
| 3725186 | 883.1.1.7 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › MMM1 | 0.51 | 40.0 | 2.89e-01 | 89.1% | 61.4% |
| 3173631 | 883.1.1.22 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › PF26547 | 0.51 | 41.0 | 2.92e-01 | 90.6% | 57.7% |
| 5076734 | 2004.1.1.164 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Roc | 0.51 | 42.0 | 3.15e-01 | 96.9% | 76.1% |
D2
high
residues 79-165
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 34.0 | 3.17e-01 | 100.0% | 41.9% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 36.0 | 4.27e-01 | 93.1% | 82.8% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 41.0 | 3.88e-01 | 70.1% | 86.2% |
| 1b06A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.59 | 33.0 | 3.68e-01 | 94.3% | 70.1% |
| 4bzaA03 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.58 | 40.0 | 4.18e-01 | 100.0% | 78.5% |
| 1vclA03 | 3.30.1750.10 | Alpha Beta › 2-Layer Sandwich › hemolytic lectin cel-iii, domain 3 › Hemolytic lectin CEL-III, C-terminal domain | 0.58 | 37.0 | 3.18e-01 | 77.0% | 38.5% |
| 1gwiA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.57 | 48.0 | 3.20e-01 | 97.7% | 54.0% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.55 | 40.0 | 4.25e-01 | 100.0% | 89.2% |
| 6cgvM01 | 1.20.120.1500 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pre-hexon-linking protein IIIa | 0.53 | 37.0 | 3.27e-01 | 72.4% | 75.4% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 35.0 | 3.62e-01 | 95.4% | 71.6% |
| 7odyC01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.52 | 36.0 | 3.57e-01 | 83.9% | 67.4% |
| 3fggA00 | 1.10.3950.10 | Mainly Alpha › Orthogonal Bundle › putative ecf-type sigma factor negative effector from bacillus cereus › putative ecf-type sigma factor negative effector from bacillus cereus | 0.52 | 41.0 | 3.56e-01 | 98.9% | 52.4% |
| 6k4yI00 | 1.10.1810.10 | Mainly Alpha › Orthogonal Bundle › Anti-sigma factor AsiA › Anti-Sigma Factor A | 0.52 | 36.0 | 3.59e-01 | 71.3% | 73.9% |
| 3ce9A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.51 | 43.0 | 3.40e-01 | 95.4% | 96.9% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.51 | 35.0 | 3.60e-01 | 95.4% | 76.2% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 39.0 | 3.41e-01 | 86.2% | 93.6% |
| 6t4hA03 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.50 | 42.0 | 3.33e-01 | 89.7% | 75.0% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4655797 | 186.1.1.1 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 | 0.79 | 70.0 | 6.78e-01 | 97.7% | 87.4% |
| 4999471 | 186.1.1.1 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 | 0.70 | 62.0 | 5.57e-01 | 98.9% | 71.7% |
| 4588041 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.64 | 46.0 | 4.63e-01 | 75.9% | 85.6% |
| 3518321 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 37.0 | 3.37e-01 | 94.3% | 43.5% |
| 3592841 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.59 | 38.0 | 4.12e-01 | 100.0% | 81.4% |
| 4003669 | 5.1.4.37 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 | 0.57 | 41.0 | 2.57e-01 | 100.0% | 13.5% |
| 3173112 | 1203.1.2.4 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Vps55 | 0.57 | 46.0 | 4.02e-01 | 89.7% | 81.5% |
| 3484930 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 31.0 | 2.96e-01 | 93.1% | 43.8% |
| 4947816 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.56 | 38.0 | 3.68e-01 | 90.8% | 61.0% |
| 4029967 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.55 | 48.0 | 4.41e-01 | 100.0% | 74.8% |
| 3522858 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 32.0 | 3.06e-01 | 100.0% | 48.6% |
| 3248730 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 32.0 | 2.98e-01 | 73.6% | 46.1% |
D3
medium
residues 188-226_291-337
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hx0K01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.56 | 41.0 | 4.22e-01 | 86.0% | 80.7% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.56 | 34.0 | 2.68e-01 | 97.7% | 29.5% |
| 6h5hA00 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.55 | 41.0 | 4.41e-01 | 88.4% | 94.4% |
| 1w98B01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 37.0 | 3.15e-01 | 80.2% | 40.8% |
| 2xv4S03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 38.0 | 3.76e-01 | 77.9% | 98.9% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3655597 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.57 | 33.0 | 3.72e-01 | 97.7% | 75.4% |
| 3222543 | 3652.1.1.0 ↗ | alpha duplicates or obligate multimers › Qua1 › Qua1 › Qua1 | 0.55 | 37.0 | 4.28e-01 | 91.9% | 100.0% |
| 3344162 | 102.1.1.30 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 | 0.55 | 40.0 | 4.20e-01 | 86.0% | 83.7% |
| 5049807 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.54 | 35.0 | 3.89e-01 | 86.0% | 86.2% |
| 3989722 | 632.24.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor C-terminal domain › GBS CAMP factor C-terminal domain | 0.54 | 37.0 | 4.17e-01 | 86.0% | 95.4% |
| 3328714 | 101.1.21.2 ↗ | alpha arrays › HTH › HTH › HTH in T7 RNA polymerase › PF29140 | 0.52 | 43.0 | 3.06e-01 | 93.0% | 92.5% |
| 4943756 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.52 | 36.0 | 3.24e-01 | 100.0% | 51.7% |
| 3247974 | 601.2.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr | 0.50 | 35.0 | 3.04e-01 | 97.7% | 45.9% |
D4
medium
residues 227-290
Domain cluster:
representative
CATH (66)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4exrA02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.72 | 48.0 | 4.69e-01 | 75.0% | 63.4% |
| 2cqaA01 | 2.40.50.360 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RuvBL1 DNA/RNA binding domain | 0.70 | 52.0 | 4.99e-01 | 82.8% | 68.9% |
| 3hi2B00 | 3.30.2310.40 | Alpha Beta › 2-Layer Sandwich › YaeB-like fold › | 0.65 | 48.0 | 4.22e-01 | 79.7% | 71.1% |
| 1d5aA01 | 3.30.342.10 | Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 | 0.64 | 49.0 | 3.75e-01 | 82.8% | 100.0% |
| 3cm1A00 | 2.30.31.20 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB | 0.63 | 54.0 | 4.33e-01 | 100.0% | 83.1% |
| 3k59A01 | 2.40.50.590 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › DNA polymerase B, N domain, beta-barrel | 0.61 | 47.0 | 4.34e-01 | 87.5% | 63.5% |
| 2kieA00 | 2.30.29.110 | Mainly Beta › Roll › PH-domain like › | 0.61 | 48.0 | 3.87e-01 | 85.9% | 50.8% |
| 2bs6A01 | 2.40.128.190 | Mainly Beta › Beta Barrel › Lipocalin › | 0.60 | 38.0 | 3.48e-01 | 71.9% | 47.6% |
| 3tfiA00 | 3.30.1360.120 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 | 0.60 | 43.0 | 2.69e-01 | 75.0% | 53.1% |
| 1ms9A01 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.60 | 43.0 | 2.70e-01 | 76.6% | 15.7% |
| 2fjlA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 47.0 | 3.65e-01 | 89.1% | 82.7% |
| 2eyqA05 | 2.40.10.170 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.60 | 43.0 | 4.44e-01 | 90.6% | 83.1% |
| 2pmaA01 | 2.40.70.10 | Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases | 0.59 | 47.0 | 3.89e-01 | 89.1% | 52.1% |
| 3fehA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 51.0 | 4.20e-01 | 100.0% | 75.0% |
| 3voqA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 48.0 | 4.08e-01 | 93.8% | 70.7% |
| 1p5tA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 51.0 | 4.36e-01 | 98.4% | 97.2% |
| 2va0A00 | 3.30.450.160 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.59 | 41.0 | 3.63e-01 | 73.4% | 96.0% |
| 4jn7A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.59 | 42.0 | 3.44e-01 | 76.6% | 39.5% |
| 2v14A00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.59 | 42.0 | 3.34e-01 | 76.6% | 63.4% |
| 4wj7D00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.58 | 47.0 | 3.92e-01 | 93.8% | 60.2% |
| 1v5vA01 | 3.30.1360.120 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 | 0.58 | 40.0 | 3.01e-01 | 73.4% | 39.6% |
| 2nvnA00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.58 | 48.0 | 4.02e-01 | 98.4% | 93.3% |
| 3p0cA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.58 | 43.0 | 3.63e-01 | 81.2% | 73.9% |
| 3nhqA02 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.58 | 40.0 | 3.22e-01 | 71.9% | 74.8% |
| 2lkoA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.57 | 47.0 | 3.80e-01 | 96.9% | 76.8% |
| 7t8tA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.57 | 45.0 | 3.73e-01 | 92.2% | 70.2% |
| 3pvlA04 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.57 | 48.0 | 4.24e-01 | 98.4% | 96.0% |
| 2d9wA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.57 | 44.0 | 3.77e-01 | 85.9% | 90.9% |
| 1xteA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.57 | 43.0 | 3.55e-01 | 81.2% | 72.4% |
| 1dz1A00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.57 | 44.0 | 4.34e-01 | 89.1% | 87.1% |
| 2lqkA00 | 2.40.10.170 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.57 | 38.0 | 3.74e-01 | 76.6% | 64.3% |
| 1j0wB00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.56 | 48.0 | 4.17e-01 | 100.0% | 95.1% |
| 3c8cB01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.56 | 42.0 | 3.36e-01 | 81.2% | 86.6% |
| 4oxwA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.55 | 39.0 | 3.39e-01 | 76.6% | 54.7% |
| 1srqA01 | 3.30.1120.160 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.55 | 44.0 | 3.63e-01 | 96.9% | 97.8% |
| 4dm5A00 | 3.30.1450.10 | Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › | 0.55 | 38.0 | 3.55e-01 | 75.0% | 75.9% |
| 4harA00 | 3.10.50.50 | Alpha Beta › Roll › Chitinase A; domain 3 › Rubella virus capsid protein | 0.55 | 40.0 | 3.60e-01 | 82.8% | 96.9% |
| 1epaA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.55 | 43.0 | 3.34e-01 | 90.6% | 68.1% |
| 2dmyA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.54 | 40.0 | 3.54e-01 | 81.2% | 52.6% |
| 2p4bB02 | 3.30.200.100 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain | 0.54 | 41.0 | 3.64e-01 | 82.8% | 95.9% |
| 2czoA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.54 | 42.0 | 3.48e-01 | 90.6% | 44.6% |
| 2vrwB02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.54 | 47.0 | 3.86e-01 | 100.0% | 80.2% |
| 3kksB00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.54 | 42.0 | 3.24e-01 | 85.9% | 49.3% |
| 1mpgA01 | 3.30.310.20 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain | 0.54 | 36.0 | 3.05e-01 | 70.3% | 59.8% |
| 4tyzA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.53 | 42.0 | 3.74e-01 | 96.9% | 67.9% |
| 3k44B00 | 3.30.2450.30 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › | 0.53 | 44.0 | 3.60e-01 | 100.0% | 76.4% |
| 2bolA03 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 40.0 | 3.61e-01 | 82.8% | 71.0% |
| 1pj5A03 | 3.30.1360.120 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 | 0.53 | 36.0 | 2.69e-01 | 73.4% | 46.5% |
| 1e2tA03 | 2.40.128.150 | Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases | 0.53 | 37.0 | 3.14e-01 | 75.0% | 69.2% |
| 2l2nA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.53 | 36.0 | 3.46e-01 | 70.3% | 69.0% |
| 2aehA03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.53 | 43.0 | 3.77e-01 | 100.0% | 88.3% |
| 7oufB01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 38.0 | 2.96e-01 | 78.1% | 47.0% |
| 5fgoA00 | 3.10.450.700 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 37.0 | 3.76e-01 | 76.6% | 80.6% |
| 1ywuA00 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.52 | 42.0 | 3.47e-01 | 92.2% | 70.4% |
| 2gfgA00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.52 | 42.0 | 3.09e-01 | 92.2% | 59.7% |
| 1whqA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.51 | 38.0 | 3.72e-01 | 81.2% | 77.5% |
| 1x49A01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.51 | 37.0 | 3.69e-01 | 79.7% | 77.1% |
| 4rzkA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 39.0 | 3.65e-01 | 87.5% | 71.3% |
| 2jheA02 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.51 | 39.0 | 3.34e-01 | 84.4% | 88.9% |
| 2v3aA03 | 3.30.390.120 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.51 | 35.0 | 3.55e-01 | 73.4% | 78.1% |
| 2hc5A01 | 3.30.160.170 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › FlaG-like | 0.51 | 42.0 | 3.77e-01 | 98.4% | 90.8% |
| 4hasA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.51 | 38.0 | 3.32e-01 | 82.8% | 68.3% |
| 4ydzA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 40.0 | 3.21e-01 | 89.1% | 85.2% |
| 4q63A00 | 2.40.10.430 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.50 | 40.0 | 3.70e-01 | 95.3% | 86.0% |
| 1pbyA02 | 2.40.128.120 | Mainly Beta › Beta Barrel › Lipocalin › Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 | 0.50 | 38.0 | 3.31e-01 | 84.4% | 65.1% |
| 2lt1A00 | 2.40.10.170 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.50 | 37.0 | 3.63e-01 | 87.5% | 70.7% |
ECOD (84)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3782562 | 101.1.8.7 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › NDC10_II | 0.87 | 80.0 | 5.83e-01 | 100.0% | 48.8% |
| 5007182 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.77 | 61.0 | 4.60e-01 | 92.2% | 36.1% |
| 3615163 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.70 | 59.0 | 5.06e-01 | 96.9% | 82.2% |
| 5039400 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.68 | 50.0 | 3.23e-01 | 79.7% | 93.7% |
| 4069753 | 295.1.1.2 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA | 0.66 | 56.0 | 4.50e-01 | 98.4% | 83.0% |
| 4492006 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.65 | 52.0 | 3.39e-01 | 85.9% | 99.6% |
| 185116 | 295.1.1.2 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA | 0.64 | 56.0 | 4.44e-01 | 100.0% | 78.8% |
| 3544514 | 2003.1.3.13 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › Prenylcys_lyase+NAD_binding_8 | 0.64 | 57.0 | 3.37e-01 | 100.0% | 82.3% |
| 5056780 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.64 | 53.0 | 4.30e-01 | 92.2% | 67.2% |
| 3591633 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.64 | 48.0 | 4.07e-01 | 81.2% | 73.6% |
| 5056578 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.64 | 52.0 | 3.36e-01 | 89.1% | 98.0% |
| 4941649 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.64 | 52.0 | 4.61e-01 | 92.2% | 77.9% |
| 5007104 | 220.1.1.219 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch | 0.63 | 52.0 | 4.48e-01 | 92.2% | 70.5% |
| 3707085 | 5.1.2.33 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › BNR_3 | 0.63 | 43.0 | 2.96e-01 | 76.6% | 20.5% |
| 3714703 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.63 | 48.0 | 4.25e-01 | 85.9% | 76.0% |
| 3241979 | 220.1.1.7 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › IRS | 0.62 | 51.0 | 4.41e-01 | 93.8% | 71.4% |
| 5013239 | 220.1.1.219 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch | 0.62 | 52.0 | 4.44e-01 | 96.9% | 97.3% |
| 3925891 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.61 | 52.0 | 4.70e-01 | 96.9% | 81.1% |
| 3473908 | 220.1.1.157 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PF29715 | 0.61 | 49.0 | 3.74e-01 | 92.2% | 46.7% |
| 3880204 | 220.1.1.199 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_NISCH_C | 0.61 | 49.0 | 3.67e-01 | 92.2% | 51.1% |
| 4931302 | 802.1.1.0 ↗ | a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 | 0.61 | 44.0 | 4.72e-01 | 90.6% | 100.0% |
| 4030120 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.61 | 52.0 | 3.13e-01 | 100.0% | 22.6% |
| 2426538 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.61 | 44.0 | 3.67e-01 | 79.7% | 47.1% |
| 3402542 | 4.8.1.2 ↗ | beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo_shadow | 0.60 | 44.0 | 4.20e-01 | 87.5% | 68.0% |
| 3906073 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.60 | 48.0 | 4.21e-01 | 92.2% | 72.4% |
| 4458952 | 220.1.1.4 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Ran_BP1 | 0.60 | 49.0 | 4.02e-01 | 98.4% | 66.7% |
| 4420094 | 304.107.1.1 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › GCV_T | 0.59 | 42.0 | 2.80e-01 | 75.0% | 68.8% |
| 3787501 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.59 | 46.0 | 3.60e-01 | 84.4% | 81.4% |
| 3572707 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.59 | 46.0 | 3.75e-01 | 85.9% | 80.8% |
| 4674129 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 48.0 | 4.14e-01 | 92.2% | 68.6% |
| 3192402 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 49.0 | 3.74e-01 | 93.8% | 56.6% |
| 4027440 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.59 | 45.0 | 3.75e-01 | 81.2% | 73.6% |
| 3764969 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 50.0 | 4.34e-01 | 98.4% | 77.9% |
| 3914585 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.59 | 46.0 | 3.98e-01 | 87.5% | 81.9% |
| 2068913 | 304.107.1.1 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › GCV_T | 0.59 | 42.0 | 3.24e-01 | 75.0% | 44.2% |
| 3996686 | 220.1.1.47 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 | 0.59 | 49.0 | 3.82e-01 | 96.9% | 58.0% |
| 4956582 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 47.0 | 3.89e-01 | 92.2% | 85.6% |
| 3742185 | 2003.1.5.26 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 | 0.58 | 47.0 | 2.97e-01 | 93.8% | 65.5% |
| 3589823 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.58 | 41.0 | 4.15e-01 | 76.6% | 90.8% |
| 3705153 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 49.0 | 3.97e-01 | 100.0% | 84.4% |
| 4979510 | 304.107.1.1 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › GCV_T | 0.58 | 40.0 | 2.70e-01 | 75.0% | 69.5% |
| 3468562 | 331.1.1.5 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › OGG_N | 0.58 | 40.0 | 3.62e-01 | 73.4% | 72.2% |
| 3176053 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 47.0 | 3.92e-01 | 98.4% | 83.1% |
| 4537304 | 11.1.1.279 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › TarS_C1 | 0.58 | 42.0 | 3.30e-01 | 79.7% | 71.7% |
| 3544563 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 44.0 | 3.85e-01 | 85.9% | 82.9% |
| 5008603 | 223.1.1.2 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS | 0.58 | 41.0 | 2.94e-01 | 75.0% | 33.7% |
| 3304391 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.58 | 44.0 | 3.51e-01 | 87.5% | 72.4% |
| 3241305 | 295.1.1.3 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA | 0.58 | 47.0 | 3.83e-01 | 98.4% | 90.7% |
| 3706713 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.57 | 42.0 | 2.55e-01 | 79.7% | 14.3% |
| 3680900 | 220.1.1.78 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_2 | 0.57 | 44.0 | 3.68e-01 | 87.5% | 79.2% |
| 3783181 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.57 | 43.0 | 3.62e-01 | 81.2% | 75.5% |
| 4115593 | 2002.1.1.30 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 | 0.56 | 42.0 | 2.68e-01 | 79.7% | 22.5% |
| 3584249 | 220.1.1.132 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › KRIT1_FRMD8_FERM_C | 0.56 | 48.0 | 4.11e-01 | 98.4% | 81.8% |
| 3820521 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.56 | 39.0 | 2.51e-01 | 73.4% | 20.3% |
| 4927363 | 802.1.1.0 ↗ | a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 | 0.56 | 45.0 | 4.32e-01 | 92.2% | 78.7% |
| 3496244 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.56 | 45.0 | 3.62e-01 | 93.8% | 54.3% |
| 3924148 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.56 | 42.0 | 3.21e-01 | 82.8% | 44.2% |
| 3864474 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.56 | 41.0 | 3.09e-01 | 79.7% | 47.9% |
| 3907293 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.56 | 44.0 | 3.88e-01 | 92.2% | 85.7% |
| 3627778 | 220.1.1.64 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C1_MyoVII | 0.55 | 46.0 | 4.10e-01 | 100.0% | 92.0% |
| 4988427 | 2003.1.5.26 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 | 0.55 | 45.0 | 2.85e-01 | 92.2% | 58.9% |
| 4966080 | 300.1.1.18 ↗ | a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › FilR1_middle | 0.55 | 47.0 | 3.64e-01 | 100.0% | 96.1% |
| 5053495 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.55 | 40.0 | 3.02e-01 | 96.9% | 31.2% |
| 5077064 | 2002.1.1.30 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 | 0.55 | 41.0 | 2.72e-01 | 84.4% | 28.9% |
| 4962132 | 300.1.1.18 ↗ | a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › FilR1_middle | 0.54 | 46.0 | 3.54e-01 | 100.0% | 93.8% |
| 3959051 | 304.107.1.0 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain | 0.54 | 38.0 | 2.75e-01 | 73.4% | 36.2% |
| 3601320 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.54 | 42.0 | 3.63e-01 | 84.4% | 92.0% |
| 3387865 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.54 | 40.0 | 3.49e-01 | 78.1% | 71.6% |
| 4184401 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.54 | 39.0 | 2.97e-01 | 78.1% | 53.1% |
| 4033840 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.53 | 44.0 | 3.22e-01 | 93.8% | 59.5% |
| 3956757 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.53 | 39.0 | 3.46e-01 | 78.1% | 93.7% |
| 3627817 | 220.1.1.47 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 | 0.53 | 45.0 | 2.99e-01 | 98.4% | 33.9% |
| 3810543 | 220.1.1.20 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH | 0.53 | 43.0 | 3.80e-01 | 100.0% | 88.2% |
| 4945424 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.53 | 41.0 | 3.33e-01 | 85.9% | 71.5% |
| 3714622 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.53 | 42.0 | 3.50e-01 | 90.6% | 79.2% |
| 5052577 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.52 | 41.0 | 3.31e-01 | 85.9% | 80.0% |
| 4295277 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.52 | 38.0 | 2.96e-01 | 78.1% | 59.3% |
| 1780023 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.52 | 40.0 | 3.55e-01 | 84.4% | 86.0% |
| 4633844 | 223.1.1.72 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › GAPES2 | 0.51 | 42.0 | 2.94e-01 | 93.8% | 68.5% |
| 4932472 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.51 | 40.0 | 3.60e-01 | 87.5% | 72.6% |
| 3851316 | 223.2.1.19 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_1 | 0.51 | 40.0 | 2.97e-01 | 84.4% | 55.9% |
| None | — | 0.51 | 40.0 | 2.70e-01 | 84.4% | 40.9% | |
| 3957881 | 213.1.1.60 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_5 | 0.51 | 35.0 | 2.97e-01 | 71.9% | 57.3% |
| 3715519 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.50 | 43.0 | 3.11e-01 | 100.0% | 51.7% |
D5
medium
residues 338-406
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3nkhA00 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.72 | 54.0 | 3.74e-01 | 82.6% | 24.9% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 53.0 | 3.94e-01 | 81.2% | 48.9% |
| 3w6vA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.70 | 50.0 | 4.34e-01 | 76.8% | 58.6% |
| 3nxcA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.69 | 52.0 | 3.87e-01 | 81.2% | 49.2% |
| 2w7nA00 | 1.10.10.2690 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.63 | 46.0 | 4.12e-01 | 97.1% | 56.4% |
| 3bcgA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 53.0 | 3.90e-01 | 100.0% | 93.2% |
| 2gfnA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 53.0 | 3.97e-01 | 100.0% | 97.4% |
| 3ljlA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 45.0 | 3.57e-01 | 79.7% | 96.6% |
| 3oioA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.61 | 49.0 | 4.27e-01 | 92.8% | 95.5% |
| 5dukB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 43.0 | 4.41e-01 | 76.8% | 82.1% |
| 4x0qA04 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.60 | 44.0 | 3.57e-01 | 79.7% | 53.5% |
| 5fglA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 42.0 | 3.02e-01 | 72.5% | 56.0% |
| 3py8A04 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.59 | 44.0 | 3.59e-01 | 82.6% | 44.4% |
| 5dajD00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 47.0 | 3.61e-01 | 95.7% | 94.3% |
| 3nnrA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 49.0 | 3.62e-01 | 100.0% | 91.6% |
| 3npiB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 47.0 | 3.52e-01 | 100.0% | 92.9% |
| 3htaC00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 39.0 | 2.87e-01 | 71.0% | 65.6% |
| 3d0sA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 39.0 | 3.73e-01 | 71.0% | 80.0% |
| 3on4D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 44.0 | 3.29e-01 | 87.0% | 65.9% |
| 3s5rB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 45.0 | 3.36e-01 | 92.8% | 78.1% |
| 3c07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 45.0 | 3.38e-01 | 98.6% | 89.3% |
| 3bhqA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 46.0 | 3.46e-01 | 100.0% | 94.6% |
| 1q48A00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.53 | 41.0 | 3.42e-01 | 87.0% | 51.5% |
| 2qtqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 45.0 | 3.36e-01 | 100.0% | 98.0% |
| 4nvsA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.51 | 40.0 | 3.27e-01 | 94.2% | 85.8% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4034069 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.91 | 66.0 | 7.36e-01 | 75.4% | 94.5% |
| 4947464 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.84 | 62.0 | 6.92e-01 | 76.8% | 96.4% |
| 3935816 | 4156.1.1.5 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › POLQ_helical | 0.82 | 56.0 | 4.13e-01 | 71.0% | 48.1% |
| 4993585 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.80 | 57.0 | 6.10e-01 | 75.4% | 93.3% |
| 3290277 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.78 | 55.0 | 6.34e-01 | 72.5% | 100.0% |
| 4608916 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.73 | 56.0 | 6.18e-01 | 79.7% | 100.0% |
| 3476699 | 101.1.1.60 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_23 | 0.71 | 55.0 | 5.08e-01 | 81.2% | 95.3% |
| 4010691 | 101.1.3.1 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE | 0.69 | 47.0 | 5.23e-01 | 71.0% | 92.7% |
| 3707219 | 4964.1.1.0 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I | 0.66 | 51.0 | 4.29e-01 | 85.5% | 70.8% |
| 3998880 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.64 | 47.0 | 4.26e-01 | 92.8% | 56.8% |
| 4973961 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.64 | 56.0 | 5.07e-01 | 98.6% | 97.9% |
| 4968115 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 44.0 | 4.42e-01 | 73.9% | 75.7% |
| 5017723 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.61 | 48.0 | 4.71e-01 | 84.1% | 96.0% |
| 3652032 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.60 | 46.0 | 4.55e-01 | 94.2% | 77.3% |
| 4996547 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 53.0 | 4.03e-01 | 98.6% | 59.4% |
| 3603081 | 101.1.2.40 ↗ | alpha arrays › HTH › HTH › winged helix domain › CPSase_L_D3 | 0.59 | 47.0 | 4.60e-01 | 87.0% | 93.3% |
| 3977377 | 101.1.2.836 ↗ | alpha arrays › HTH › HTH › winged helix domain › Terminase_5 | 0.59 | 48.0 | 4.13e-01 | 87.0% | 86.7% |
| 3957236 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.57 | 40.0 | 3.56e-01 | 75.4% | 100.0% |
| 4997858 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.56 | 41.0 | 3.21e-01 | 81.2% | 79.4% |