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IMGVR_UViG_3300018024_000012-3300018024-Ga0187881_1000077858

Arc-Vir

IMGVR_UViG_3300018024_000012-3300018024-Ga0187881_1000077858

Quality

74.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 14-70
PDB
Domain cluster: representative
CATH (82)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qjvA03 3.30.70.3110 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 45.0 4.40e-01 82.5% 59.7%
1ef0B02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.70 58.0 4.06e-01 100.0% 28.7%
3ou2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 47.0 3.24e-01 78.9% 80.4%
2dchX02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.65 53.0 4.47e-01 100.0% 58.6%
7n0eB02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.64 56.0 4.39e-01 98.2% 95.9%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.64 51.0 4.00e-01 89.5% 44.4%
1r62A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.64 56.0 4.27e-01 100.0% 93.4%
4hh2B03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.64 47.0 3.92e-01 78.9% 94.0%
8dy9I01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.64 52.0 3.70e-01 100.0% 27.7%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.64 52.0 4.36e-01 100.0% 53.5%
2o0bA01 3.65.10.10 Alpha Beta › Alpha-beta prism › UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain › Enolpyruvate transferase domain 0.63 52.0 3.50e-01 98.2% 24.4%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.63 52.0 4.45e-01 100.0% 65.0%
1id0A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.63 54.0 4.06e-01 98.2% 94.5%
2lrrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.62 54.0 5.07e-01 100.0% 78.6%
1lfpA03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.62 43.0 4.01e-01 75.4% 56.2%
3hnrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 45.0 3.21e-01 80.7% 89.1%
3ajdA01 3.30.70.1170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 0.62 41.0 4.04e-01 78.9% 65.0%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.61 51.0 4.69e-01 98.2% 70.7%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.61 48.0 3.75e-01 89.5% 75.4%
1b3qB02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.61 53.0 3.72e-01 98.2% 96.8%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.61 49.0 3.77e-01 94.7% 81.5%
1s2oA02 3.90.1070.10 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.60 52.0 4.92e-01 100.0% 90.1%
3ehgA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.60 52.0 4.10e-01 100.0% 68.8%
2pt7G02 3.30.1370.180 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.59 50.0 4.76e-01 98.2% 80.6%
4gt8A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.59 51.0 3.95e-01 100.0% 66.2%
4yhxA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.59 48.0 3.79e-01 100.0% 47.5%
5gt8D02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.59 45.0 3.65e-01 87.7% 91.0%
2y8yA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.59 39.0 3.50e-01 70.2% 70.9%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 42.0 3.73e-01 82.5% 51.8%
4qpkB02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.59 51.0 3.92e-01 100.0% 73.1%
2ex5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.59 48.0 3.42e-01 100.0% 32.9%
4r3aA02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.58 50.0 3.80e-01 98.2% 90.8%
1zvpD00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.58 49.0 3.80e-01 96.5% 78.6%
4z1xA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.58 48.0 3.75e-01 100.0% 44.1%
2ctfA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.58 39.0 3.37e-01 71.9% 46.1%
8c9vA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 47.0 3.39e-01 93.0% 76.8%
2pq0A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.58 49.0 4.18e-01 100.0% 92.0%
6vudA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.58 47.0 4.48e-01 100.0% 81.3%
1af5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.58 47.0 3.84e-01 100.0% 52.4%
2pmbA01 3.30.1850.10 Alpha Beta › 2-Layer Sandwich › MCP/YpsA-like › MoCo carrier protein-like 0.57 39.0 3.22e-01 70.2% 68.2%
5hvqC01 3.90.1150.220 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.57 48.0 4.38e-01 100.0% 88.7%
3qfhA01 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.57 41.0 4.03e-01 87.7% 70.8%
1rzmA01 3.30.70.1140 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 0.56 46.0 4.24e-01 96.5% 75.0%
4iw7A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 45.0 3.76e-01 98.2% 47.8%
3lcvB02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 3.24e-01 100.0% 26.7%
3cx5A01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 43.0 3.02e-01 86.0% 35.6%
2lfvA00 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.56 42.0 3.58e-01 86.0% 54.7%
2ebbA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.56 44.0 3.84e-01 93.0% 58.3%
2f1fA02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.56 43.0 4.00e-01 93.0% 65.4%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.56 44.0 4.07e-01 91.2% 67.5%
2pjdA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 3.36e-01 93.0% 76.3%
7xinA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 46.0 3.87e-01 100.0% 63.3%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 37.0 3.58e-01 70.2% 59.1%
1s67L00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 41.0 3.28e-01 80.7% 88.2%
1whvA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.56 40.0 3.49e-01 82.5% 50.0%
3zieD00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.55 48.0 4.30e-01 98.2% 68.3%
3mczA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 44.0 2.96e-01 93.0% 66.3%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.55 41.0 3.77e-01 89.5% 63.2%
1ka8A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 47.0 3.97e-01 100.0% 79.0%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 43.0 3.55e-01 98.2% 47.7%
3hz7A00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.55 48.0 4.43e-01 100.0% 78.1%
4js8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 43.0 3.83e-01 93.0% 82.0%
1x60A01 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.54 41.0 3.91e-01 87.7% 69.4%
2pcrA02 3.40.190.80 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.54 48.0 3.81e-01 100.0% 92.2%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.54 41.0 3.90e-01 89.5% 71.6%
1lfwA03 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 41.0 3.62e-01 87.7% 65.9%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 41.0 3.22e-01 91.2% 77.8%
3hr6A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 42.0 3.18e-01 93.0% 56.7%
1bccA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.53 41.0 2.84e-01 87.7% 36.4%
2avdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 40.0 2.84e-01 91.2% 47.0%
2fgcA03 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.52 40.0 3.72e-01 89.5% 68.4%
4erdA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 39.0 3.33e-01 89.5% 61.1%
6w72A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 40.0 3.18e-01 89.5% 79.4%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 42.0 3.61e-01 100.0% 59.0%
4lr4A01 2.60.120.1420 Mainly Beta › Sandwich › Jelly Rolls › 0.51 42.0 3.12e-01 100.0% 72.7%
8k1fC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.03e-01 100.0% 34.7%
3c3pA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 41.0 3.00e-01 100.0% 68.7%
3ntvA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 42.0 2.95e-01 100.0% 35.2%
2fl4A02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 40.0 3.46e-01 96.5% 89.4%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 38.0 3.33e-01 91.2% 53.4%
4avaA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 39.0 2.84e-01 91.2% 69.4%
2nq2D00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 43.0 2.85e-01 100.0% 83.9%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3706630 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.72 48.0 4.01e-01 70.2% 49.0%
4963769 328.5.1.6 a+b two layers › IF3-like › SirA-like › SirA-like › DUF2249 0.71 53.0 4.66e-01 80.7% 97.6%
4416593 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.70 47.0 4.07e-01 70.2% 61.1%
4806761 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.69 51.0 4.17e-01 78.9% 65.7%
5023543 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.68 55.0 4.76e-01 100.0% 55.0%
4971000 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.68 57.0 4.90e-01 100.0% 57.0%
5028300 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.68 55.0 4.90e-01 100.0% 62.4%
3602223 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.68 57.0 4.93e-01 100.0% 60.0%
3604140 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.67 55.0 3.96e-01 100.0% 29.7%
4988179 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.67 47.0 4.60e-01 75.4% 67.2%
4978366 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.67 53.0 5.10e-01 100.0% 77.1%
4934415 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.67 57.0 5.55e-01 100.0% 92.3%
4945934 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.67 55.0 4.51e-01 100.0% 48.7%
4250326 328.5.1.5 a+b two layers › IF3-like › SirA-like › SirA-like › AnfO_nitrog 0.66 53.0 4.74e-01 87.7% 98.8%
5049729 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 58.0 5.28e-01 96.5% 80.0%
4978474 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.66 53.0 4.19e-01 100.0% 40.7%
4997606 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.66 53.0 4.05e-01 100.0% 35.5%
3950275 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.66 55.0 4.98e-01 100.0% 76.5%
4678773 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.66 45.0 4.16e-01 73.7% 54.7%
4025594 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.66 44.0 4.17e-01 70.2% 64.3%
4943246 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.65 54.0 4.64e-01 100.0% 56.0%
5029252 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.65 55.0 4.46e-01 100.0% 53.3%
4992653 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.65 57.0 5.33e-01 98.2% 81.4%
4889884 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.65 49.0 3.48e-01 80.7% 39.8%
4960260 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.65 56.0 5.30e-01 100.0% 95.7%
5080958 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.65 56.0 5.16e-01 100.0% 90.7%
4938255 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.65 52.0 4.77e-01 100.0% 67.5%
4496753 241.1.1.8 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF2170 0.65 53.0 4.12e-01 93.0% 50.8%
5013819 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.65 54.0 5.30e-01 100.0% 93.8%
1159602 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.65 53.0 4.46e-01 100.0% 58.0%
4988628 328.5.1.6 a+b two layers › IF3-like › SirA-like › SirA-like › DUF2249 0.64 51.0 4.95e-01 100.0% 76.9%
4953268 327.11.2.83 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_DUF2096_C 0.64 47.0 4.59e-01 80.7% 73.8%
3604362 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.64 50.0 4.68e-01 100.0% 69.3%
5066702 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.64 55.0 5.05e-01 100.0% 85.3%
5020125 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.63 54.0 5.12e-01 100.0% 94.3%
4962130 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.63 55.0 4.78e-01 100.0% 96.7%
3282307 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.63 51.0 4.51e-01 100.0% 58.9%
3521725 327.11.2.55 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF26774 0.63 47.0 4.13e-01 80.7% 61.2%
4937054 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.63 52.0 4.44e-01 100.0% 59.0%
4993483 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.63 52.0 4.41e-01 100.0% 55.2%
5008116 304.24.1.39 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › DUF790 0.63 43.0 3.71e-01 84.2% 43.2%
4654074 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.62 49.0 4.28e-01 89.5% 61.1%
5028488 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.62 52.0 4.39e-01 100.0% 59.0%
4041570 327.19.1.1 a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.62 42.0 3.62e-01 71.9% 43.2%
4997133 306.3.1.1 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.62 49.0 4.21e-01 89.5% 57.9%
3407611 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.61 52.0 4.77e-01 100.0% 73.3%
3639719 304.8.1.10 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_7 0.61 43.0 3.88e-01 75.4% 62.5%
4519248 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.61 41.0 4.32e-01 71.9% 94.0%
4200948 242.1.1.2 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.61 50.0 4.34e-01 100.0% 61.0%
4987785 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.60 51.0 4.96e-01 100.0% 95.4%
3972097 304.14.1.0 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) 0.60 42.0 3.92e-01 75.4% 60.0%
4377946 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.60 52.0 4.04e-01 100.0% 46.2%
4033306 2011.1.1.23 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › M20_dimer 0.60 48.0 3.38e-01 91.2% 40.5%
3738415 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.60 45.0 3.99e-01 87.7% 55.3%
4603561 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.59 46.0 4.24e-01 89.5% 66.3%
3898070 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.59 52.0 4.87e-01 100.0% 91.4%
3205225 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.59 48.0 4.06e-01 100.0% 52.7%
6558 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.59 50.0 3.72e-01 100.0% 84.5%
4955075 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.59 50.0 4.67e-01 100.0% 97.3%
4975750 328.5.1.1 a+b two layers › IF3-like › SirA-like › SirA-like › TusA 0.58 49.0 4.42e-01 98.2% 67.5%
5078195 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 49.0 4.56e-01 100.0% 96.0%
3291625 304.154.1.1 a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain › GGDEF_2 0.58 42.0 3.30e-01 77.2% 50.8%
3357930 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.58 49.0 4.49e-01 100.0% 72.0%
5082051 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 49.0 4.32e-01 100.0% 70.0%
3644629 10.12.1.1 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding 0.58 43.0 3.33e-01 91.2% 33.6%
5010185 328.5.1.0 a+b two layers › IF3-like › SirA-like › SirA-like 0.58 45.0 4.32e-01 100.0% 72.9%
5015450 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.58 43.0 3.83e-01 78.9% 56.2%
4419954 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.58 39.0 3.85e-01 71.9% 63.1%
4981701 328.5.1.1 a+b two layers › IF3-like › SirA-like › SirA-like › TusA 0.58 47.0 4.57e-01 100.0% 80.0%
5043867 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.58 40.0 3.75e-01 75.4% 68.0%
4931923 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.57 44.0 4.05e-01 89.5% 73.8%
3972855 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.56 41.0 3.92e-01 86.0% 73.3%
3369681 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.56 38.0 3.71e-01 71.9% 73.8%
4029616 306.9.1.0 a+b two layers › Glucose permease domain IIB-like › MecA substrate binding domain › MecA substrate binding domain 0.56 43.0 4.08e-01 86.0% 91.4%
5078855 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.56 42.0 4.00e-01 89.5% 78.7%
3494198 328.7.1.0 a+b two layers › IF3-like › Smr domain › Smr domain 0.55 48.0 3.37e-01 100.0% 37.4%
3953697 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.55 47.0 4.03e-01 98.2% 61.1%
5063797 304.165.1.0 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 0.55 45.0 3.64e-01 100.0% 45.8%
4217761 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.55 42.0 3.88e-01 89.5% 70.9%
4131749 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.55 44.0 3.76e-01 100.0% 51.8%
3976762 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.55 41.0 3.92e-01 93.0% 68.0%
3164039 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.54 40.0 3.77e-01 84.2% 64.9%
4989805 328.5.1.0 a+b two layers › IF3-like › SirA-like › SirA-like 0.54 44.0 4.18e-01 100.0% 77.1%
4431836 2003.1.5.25 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.54 44.0 3.12e-01 100.0% 27.9%
3539441 304.9.1.15 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RNA_bind 0.54 39.0 3.51e-01 82.5% 55.6%
4887765 3623.1.1.1 a+b two layers › Uncharacterized protein VC_0899 › Uncharacterized protein VC_0899 › Uncharacterized protein VC_0899 › DUF4478 0.54 41.0 3.23e-01 82.5% 64.5%
4028119 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 44.0 4.25e-01 100.0% 87.1%
3619798 3122.1.1.1 a+b complex topology › MESD › MESD › MESD › Mesd 0.54 38.0 3.14e-01 82.5% 40.0%
3268629 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 43.0 4.15e-01 98.2% 95.7%
5051083 328.7.1.1 a+b two layers › IF3-like › Smr domain › Smr domain › Smr 0.53 45.0 4.01e-01 100.0% 76.5%
5003906 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.51 40.0 3.53e-01 93.0% 81.1%
D2 high residues 119-176
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u78A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 59.0 6.43e-01 91.4% 100.0%
2rn7A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 68.0 6.57e-01 100.0% 83.3%
3solA00 1.20.58.1630 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS 0.69 58.0 5.08e-01 96.6% 72.5%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.66 56.0 5.27e-01 98.3% 87.5%
4iejA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.65 53.0 4.96e-01 96.6% 74.7%
5dicA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.63 44.0 3.61e-01 74.1% 91.3%
3e22A03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.63 43.0 4.45e-01 86.2% 75.9%
2h5nC00 1.10.3680.10 Mainly Alpha › Orthogonal Bundle › TerB-like › TerB-like 0.63 53.0 4.23e-01 98.3% 46.0%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.62 53.0 4.86e-01 100.0% 79.7%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 46.0 4.58e-01 94.8% 78.0%
2btoA03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 43.0 4.47e-01 86.2% 81.5%
2btqB03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.59 43.0 4.48e-01 86.2% 84.9%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.59 50.0 4.40e-01 96.6% 64.7%
4a18Q01 1.10.10.1760 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L36 0.59 50.0 4.75e-01 98.3% 89.9%
2vj4A01 1.10.10.2060 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.59 46.0 4.14e-01 98.3% 60.0%
3pr6A00 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 49.0 3.75e-01 96.6% 75.2%
6pw7A02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.58 45.0 4.31e-01 100.0% 71.8%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 48.0 4.39e-01 98.3% 70.7%
3djaA01 1.20.920.70 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.57 39.0 3.03e-01 74.1% 37.2%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 40.0 3.57e-01 74.1% 54.3%
3e74A02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.56 46.0 2.94e-01 96.6% 21.1%
2p67A01 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 41.0 4.34e-01 89.7% 90.4%
2xppA00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.55 44.0 3.31e-01 86.2% 72.3%
4oa3A00 3.10.310.50 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.55 44.0 3.35e-01 87.9% 98.6%
4w9rA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 40.0 3.51e-01 82.8% 78.7%
1ashA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 44.0 3.39e-01 98.3% 50.3%
1r3dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 41.0 2.77e-01 91.4% 60.7%
1gs0A01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.52 43.0 3.50e-01 100.0% 69.0%
2efeA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.52 42.0 3.91e-01 94.8% 88.9%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.51 44.0 3.56e-01 98.3% 68.1%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3409418 101.1.1.244 alpha arrays › HTH › HTH › Three-helical HTH › HTH_TIMELESS 0.79 67.0 6.16e-01 93.1% 72.0%
3781118 101.1.1.46 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_2 0.78 69.0 5.91e-01 98.3% 64.4%
3185107 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.77 64.0 6.04e-01 91.4% 81.4%
4464648 101.1.2.244 alpha arrays › HTH › HTH › winged helix domain › HTH_21 0.73 58.0 5.66e-01 91.4% 78.5%
3991622 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.73 59.0 5.36e-01 91.4% 77.5%
4274627 101.1.1.266 alpha arrays › HTH › HTH › Three-helical HTH › Transposase_mut 0.72 59.0 5.93e-01 100.0% 90.0%
5013811 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 61.0 6.25e-01 94.8% 98.2%
3490008 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 56.0 5.46e-01 91.4% 81.5%
3337098 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.69 61.0 5.22e-01 100.0% 61.1%
3176081 101.1.16.1 alpha arrays › HTH › HTH › Ribosomal protein L11, C-terminal domain › Ribosomal_L11 0.69 52.0 4.59e-01 79.3% 95.2%
3611249 230.4.1.0 a+b two layers › T-fold › ApbE-like › ApbE-like 0.68 47.0 3.33e-01 74.1% 81.1%
3810208 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.67 57.0 5.54e-01 98.3% 98.5%
3463735 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.64 54.0 5.50e-01 94.8% 100.0%
3853685 1091.1.1.0 alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 0.63 53.0 5.26e-01 93.1% 95.0%
3468869 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 52.0 5.36e-01 94.8% 100.0%
4257704 301.6.1.0 a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like 0.60 43.0 2.92e-01 86.2% 20.7%
3288394 632.2.1.17 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1707 0.58 44.0 4.51e-01 79.3% 87.3%
3708001 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.57 46.0 4.43e-01 96.6% 100.0%
5013583 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 48.0 4.21e-01 96.6% 62.2%
3277930 632.2.1.17 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1707 0.56 40.0 4.35e-01 75.9% 92.0%
3315647 185.1.1.4 alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Prolamin_like 0.54 46.0 4.09e-01 96.6% 65.9%
D3 high residues 211-256
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ug2A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.82 72.0 6.97e-01 100.0% 90.4%
1ignB02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.81 71.0 5.65e-01 100.0% 54.3%
2ia0A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 66.0 6.32e-01 100.0% 79.6%
5nl9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 68.0 5.66e-01 100.0% 53.6%
3lcnB00 1.10.340.40 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain 0.79 68.0 5.40e-01 100.0% 62.9%
4rayA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 69.0 5.65e-01 100.0% 57.6%
3x1oA00 1.20.120.1790 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.79 67.0 4.75e-01 100.0% 34.9%
1ignA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.79 69.0 5.48e-01 100.0% 76.3%
4fcyA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.79 65.0 5.59e-01 100.0% 57.7%
3eyyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 66.0 5.55e-01 100.0% 58.5%
2xigA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 65.0 5.35e-01 100.0% 53.8%
3zqcA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.78 65.0 5.87e-01 100.0% 68.8%
2r0qC02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.77 56.0 5.36e-01 100.0% 67.3%
1xriA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.76 64.0 4.44e-01 95.7% 29.1%
1tbxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 64.0 5.19e-01 100.0% 52.2%
3dfgA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 62.0 6.14e-01 95.7% 93.8%
7s03A01 1.10.10.1450 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.72 60.0 5.91e-01 97.8% 96.0%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.72 49.0 3.59e-01 71.7% 27.4%
3u50C01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 54.0 3.92e-01 82.6% 42.5%
1x4qA01 1.20.1390.10 Mainly Alpha › Up-down Bundle › PWI domain › PWI domain 0.71 57.0 5.19e-01 100.0% 81.7%
4a0zA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 55.0 5.22e-01 97.8% 71.2%
3e1sA01 1.10.10.2220 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.71 59.0 4.79e-01 100.0% 77.9%
3e3vA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 59.0 5.68e-01 97.8% 86.8%
1ci4A00 1.10.150.40 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Barrier-to-autointegration factor, BAF 0.70 59.0 4.92e-01 100.0% 77.3%
2cobA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.70 55.0 5.65e-01 100.0% 95.5%
4ye6A02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.70 57.0 5.37e-01 97.8% 96.6%
2mgqA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.68 55.0 5.04e-01 100.0% 73.5%
4eqqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 55.0 5.53e-01 95.7% 91.7%
2j4jF00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.67 52.0 3.41e-01 91.3% 60.6%
4nmyA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.67 56.0 3.76e-01 100.0% 72.6%
3mstA00 3.40.190.200 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.67 52.0 3.40e-01 93.5% 81.1%
1bjaA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 54.0 4.41e-01 100.0% 62.1%
2b4lA02 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.65 51.0 3.61e-01 91.3% 63.1%
3tjmA02 1.10.1470.20 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2 0.65 54.0 4.50e-01 100.0% 61.1%
4dccA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 52.0 4.61e-01 100.0% 86.5%
2lpeA02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.63 52.0 4.63e-01 97.8% 80.3%
4ixjA01 3.30.1300.80 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.63 50.0 4.39e-01 95.7% 70.1%
2iieA01 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.63 43.0 3.42e-01 71.7% 30.6%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 41.0 3.16e-01 100.0% 29.5%
4cvnA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 46.0 3.25e-01 93.5% 64.8%
1dj8A00 1.10.890.10 Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › HNS-dependent expression A 0.60 47.0 4.15e-01 97.8% 70.9%
2of5H00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.59 41.0 3.38e-01 78.3% 68.0%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.59 46.0 3.74e-01 91.3% 63.9%
2yviA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.58 43.0 3.57e-01 82.6% 58.4%
2doeA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.58 46.0 4.00e-01 97.8% 56.6%
2b61A02 1.10.1740.110 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.57 44.0 3.58e-01 93.5% 91.3%
2ld7B00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.57 43.0 3.83e-01 89.1% 74.7%
2b0cA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.56 46.0 4.25e-01 100.0% 100.0%
6hxpA01 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.56 45.0 3.64e-01 97.8% 64.6%
3p2mA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 44.0 2.79e-01 95.7% 49.1%
3rbtA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 40.0 3.14e-01 95.7% 47.9%
1tjcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 36.0 3.07e-01 84.8% 45.3%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5021717 101.1.1.562 alpha arrays › HTH › HTH › Three-helical HTH › PF28505 0.92 74.0 5.18e-01 89.1% 30.8%
4983508 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.91 81.0 6.96e-01 100.0% 64.3%
5004914 101.35.1.40 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › DUF1699 0.90 76.0 7.06e-01 95.7% 74.1%
3992048 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.90 81.0 7.61e-01 100.0% 85.5%
4978129 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.88 79.0 4.54e-01 100.0% 11.2%
4944767 101.1.2.883 alpha arrays › HTH › HTH › winged helix domain › Radical_SAM 0.88 77.0 6.50e-01 100.0% 60.0%
3856707 101.1.1.89 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding_7 0.87 77.0 6.55e-01 100.0% 61.3%
3740014 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.86 74.0 6.33e-01 100.0% 61.4%
3479013 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.85 75.0 6.68e-01 100.0% 89.2%
3724532 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.85 71.0 5.19e-01 100.0% 35.8%
4464648 101.1.2.244 alpha arrays › HTH › HTH › winged helix domain › HTH_21 0.84 70.0 6.32e-01 95.7% 70.8%
3928773 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 73.0 6.21e-01 100.0% 61.3%
5045747 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.83 71.0 5.80e-01 100.0% 52.2%
4014657 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 76.0 7.09e-01 100.0% 83.6%
4501343 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.82 74.0 6.99e-01 100.0% 87.3%
167309 592.2.1.3 alpha arrays › PWI domain-like › YugE-like › YugE-like › Nab2 0.82 73.0 5.56e-01 100.0% 56.2%
3800383 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.82 69.0 6.30e-01 100.0% 72.3%
4942265 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.82 70.0 5.79e-01 100.0% 54.1%
3207944 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.82 72.0 7.02e-01 100.0% 96.0%
4927804 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 66.0 5.62e-01 100.0% 56.0%
5040994 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 66.0 5.64e-01 100.0% 56.0%
4978898 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.81 68.0 6.90e-01 97.8% 95.6%
4981283 613.1.1.0 alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 0.81 70.0 4.51e-01 100.0% 21.9%
3970291 101.1.1.217 alpha arrays › HTH › HTH › Three-helical HTH › RsmI_C 0.81 66.0 6.66e-01 97.8% 95.6%
3828702 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.81 69.0 6.37e-01 100.0% 75.0%
3783147 101.1.2.212 alpha arrays › HTH › HTH › winged helix domain › Cac1_C 0.81 70.0 6.16e-01 100.0% 77.1%
3960745 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.80 66.0 6.67e-01 95.7% 97.8%
3451532 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.79 66.0 6.15e-01 100.0% 75.0%
3940641 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.79 65.0 5.97e-01 100.0% 70.8%
4012282 101.1.1.46 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_2 0.79 68.0 6.14e-01 100.0% 76.9%
3480768 101.1.1.286 alpha arrays › HTH › HTH › Three-helical HTH › PF27813 0.79 68.0 5.27e-01 100.0% 48.6%
3239718 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.78 66.0 6.01e-01 100.0% 76.9%
5012836 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.78 66.0 4.09e-01 100.0% 19.6%
4587778 101.1.2.25 alpha arrays › HTH › HTH › winged helix domain › FUR 0.78 65.0 4.86e-01 100.0% 40.8%
4998572 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 66.0 5.49e-01 100.0% 55.3%
3271713 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 65.0 5.77e-01 100.0% 81.4%
3525714 101.1.1.286 alpha arrays › HTH › HTH › Three-helical HTH › PF27813 0.77 64.0 5.13e-01 100.0% 46.0%
3657853 101.1.1.210 alpha arrays › HTH › HTH › Three-helical HTH › Cac1_C 0.77 65.0 5.91e-01 100.0% 87.7%
4406214 101.1.2.70 alpha arrays › HTH › HTH › winged helix domain › PqqD 0.77 65.0 5.26e-01 100.0% 49.5%
3672635 101.1.1.295 alpha arrays › HTH › HTH › Three-helical HTH › HTH_70 0.76 63.0 5.54e-01 100.0% 66.7%
4949368 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.76 63.0 5.98e-01 97.8% 78.2%
4988076 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 62.0 5.66e-01 100.0% 76.5%
3781503 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.76 64.0 6.11e-01 100.0% 89.1%
4034503 101.26.1.1 alpha arrays › HTH › Tex N-terminal domain › Tex N-terminal domain › Tex_N 0.76 64.0 5.81e-01 100.0% 70.8%
5025549 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 65.0 5.84e-01 100.0% 81.5%
4973028 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 66.0 5.52e-01 100.0% 72.5%
4959424 103.6.1.0 alpha arrays › RuvA-C › FGAM synthase PurL, linker domain › FGAM synthase PurL, linker domain 0.75 64.0 6.11e-01 100.0% 92.7%
4255518 4973.1.1.0 alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core 0.74 63.0 5.36e-01 100.0% 65.0%
4024983 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 62.0 5.31e-01 100.0% 76.2%
3641099 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.74 60.0 5.70e-01 100.0% 83.3%
3971692 5060.2.1.0 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain 0.72 53.0 3.97e-01 82.6% 43.2%
4997248 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 60.0 4.79e-01 100.0% 82.0%
4028411 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 60.0 5.49e-01 100.0% 87.7%
3236431 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 58.0 5.20e-01 100.0% 64.3%
4019040 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.71 58.0 4.06e-01 100.0% 45.3%
3810921 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.71 57.0 5.43e-01 100.0% 88.3%
3791697 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 60.0 5.69e-01 97.8% 85.5%
4176831 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 60.0 4.39e-01 100.0% 38.5%
5052346 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.70 58.0 5.42e-01 100.0% 75.0%
5025960 101.1.1.558 alpha arrays › HTH › HTH › Three-helical HTH › DUF7523 0.70 57.0 5.49e-01 95.7% 87.3%
3337658 610.3.1.3 alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain › tRNA_synt_1c_R1 0.69 57.0 3.92e-01 100.0% 29.2%
3707222 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.69 56.0 5.43e-01 100.0% 81.8%
3993576 610.3.1.3 alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain › tRNA_synt_1c_R1 0.69 57.0 4.01e-01 100.0% 32.7%
3504507 610.3.1.3 alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain › tRNA_synt_1c_R1 0.68 57.0 3.89e-01 100.0% 29.2%
5038818 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.68 54.0 3.46e-01 100.0% 16.8%
4027285 101.1.1.3 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding 0.68 55.0 4.71e-01 100.0% 55.3%
3573652 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.68 52.0 5.17e-01 97.8% 86.0%
5010816 5060.2.1.0 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain 0.67 57.0 4.32e-01 100.0% 62.5%
3575777 101.43.1.0 alpha arrays › HTH › Phage G20C small terminase N-terminal domain › Phage G20C small terminase N-terminal domain 0.67 56.0 5.51e-01 100.0% 96.0%
4947212 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.67 53.0 4.23e-01 91.3% 61.0%
4271175 101.1.2.498 alpha arrays › HTH › HTH › winged helix domain › PF25870 0.67 55.0 4.06e-01 100.0% 34.1%
1738563 610.3.1.3 alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain › tRNA_synt_1c_R1 0.66 53.0 3.71e-01 100.0% 29.5%
3618803 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.66 56.0 5.19e-01 100.0% 78.3%
4506746 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.66 54.0 3.73e-01 100.0% 60.5%
4207615 170.2.1.28 alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain › PNMA 0.63 51.0 4.63e-01 93.5% 84.6%
3257352 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.62 49.0 4.33e-01 100.0% 76.2%
3523524 304.9.1.37 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PNMA 0.61 47.0 4.33e-01 91.3% 84.6%
4929245 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.61 45.0 4.13e-01 89.1% 68.6%
3870636 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 44.0 3.97e-01 78.3% 72.3%
3736509 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.59 51.0 3.14e-01 100.0% 31.0%
3821967 509.1.1.1 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.59 48.0 4.18e-01 95.7% 66.7%
D4 high residues 308-369
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.88 80.0 5.24e-01 100.0% 41.3%
3p01A01 6.10.140.590 Special › Helix non-globular › Helix Hairpins › 0.85 63.0 5.65e-01 77.4% 57.8%
8b9zK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 68.0 5.98e-01 91.9% 68.1%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.80 62.0 5.50e-01 82.3% 67.4%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.79 70.0 5.88e-01 100.0% 57.9%
2nr5A00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.79 62.0 6.42e-01 88.7% 91.4%
4i43B02 3.30.43.40 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain 0.79 61.0 4.89e-01 82.3% 76.3%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.77 65.0 5.11e-01 93.5% 70.6%
3g3oA00 3.20.100.30 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › VTC, catalytic tunnel domain 0.76 52.0 3.34e-01 79.0% 15.7%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 67.0 4.61e-01 95.2% 84.2%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.75 58.0 4.42e-01 83.9% 36.7%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.75 60.0 4.55e-01 88.7% 37.6%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 62.0 6.07e-01 91.9% 86.6%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.74 65.0 6.05e-01 100.0% 79.2%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 64.0 6.41e-01 100.0% 95.2%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.72 63.0 4.53e-01 100.0% 92.9%
1a52A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.71 61.0 4.04e-01 96.8% 24.3%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.67 58.0 4.10e-01 100.0% 30.5%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 59.0 5.04e-01 100.0% 69.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 61.0 5.79e-01 100.0% 87.3%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 50.0 3.63e-01 85.5% 28.0%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.65 52.0 3.63e-01 91.9% 25.9%
3vkgA14 6.10.140.1060 Special › Helix non-globular › Helix Hairpins › 0.65 55.0 5.14e-01 100.0% 75.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.64 52.0 4.60e-01 93.5% 62.2%
4a18Q01 1.10.10.1760 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L36 0.64 42.0 4.07e-01 71.0% 60.9%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.63 56.0 5.40e-01 98.4% 90.1%
1grjA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.61 55.0 5.22e-01 100.0% 83.8%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.61 46.0 3.74e-01 82.3% 41.9%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3486218 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.92 85.0 7.23e-01 100.0% 66.3%
3184585 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.88 81.0 7.78e-01 100.0% 88.6%
3839762 1008.1.1.0 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.87 70.0 6.29e-01 100.0% 63.5%
3972992 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.86 77.0 7.57e-01 98.4% 95.4%
3567180 4177.1.1.61 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PLC-beta_C 0.85 76.0 5.04e-01 100.0% 38.3%
5034208 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.83 75.0 5.77e-01 100.0% 48.1%
3784055 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.82 72.0 5.68e-01 100.0% 57.7%
3385570 5043.1.1.21 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › DUF2393 0.81 72.0 6.73e-01 98.4% 81.3%
5017842 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 69.0 6.26e-01 98.4% 71.8%
3344802 6158.1.1.0 alpha bundles › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region 0.79 69.0 6.80e-01 100.0% 90.8%
3273753 627.1.1.0 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.78 57.0 4.86e-01 82.3% 48.0%
4945035 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 66.0 6.76e-01 91.9% 93.3%
5040194 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.78 68.0 5.83e-01 100.0% 68.0%
5006517 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.77 67.0 6.02e-01 95.2% 71.4%
2546344 3826.1.1.1 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Trns_repr_metal 0.74 60.0 6.17e-01 90.3% 95.0%
3960393 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.73 59.0 4.75e-01 88.7% 74.2%
3951780 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.73 62.0 3.79e-01 100.0% 15.0%
3312910 603.1.1.111 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TBCC_N 0.72 59.0 5.32e-01 95.2% 64.4%
4349607 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 62.0 5.11e-01 100.0% 94.5%
3780651 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.68 59.0 5.87e-01 95.2% 100.0%
2456957 192.13.1.1 alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 0.67 52.0 5.47e-01 85.5% 92.9%
3925075 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 47.0 4.51e-01 83.9% 70.0%
3643105 6026.1.1.1 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.63 52.0 3.92e-01 91.9% 56.1%