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IMGVR_UViG_3300018080_003942-3300018080-Ga0180433_1000026995
Arc-VirIMGVR_UViG_3300018080_003942-3300018080-Ga0180433_1000026995
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 281-365
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.72 | 60.0 | 5.34e-01 | 90.6% | 81.5% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 56.0 | 4.91e-01 | 87.1% | 74.6% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.65 | 49.0 | 4.27e-01 | 90.6% | 52.7% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.64 | 57.0 | 4.67e-01 | 100.0% | 83.4% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 53.0 | 4.54e-01 | 90.6% | 87.2% |
| 6ldkA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.63 | 53.0 | 4.29e-01 | 95.3% | 63.4% |
| 8gq6B01 | 3.30.710.10 | Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A | 0.62 | 35.0 | 3.10e-01 | 90.6% | 34.8% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 42.0 | 3.50e-01 | 72.9% | 58.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 42.0 | 3.48e-01 | 72.9% | 56.8% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 46.0 | 4.36e-01 | 87.1% | 69.6% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 46.0 | 4.29e-01 | 89.4% | 91.7% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 39.0 | 3.30e-01 | 70.6% | 55.7% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 47.0 | 4.35e-01 | 90.6% | 91.7% |
| 2r6tB01 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.57 | 45.0 | 3.68e-01 | 88.2% | 92.8% |
| 1fw8A01 | 3.40.50.1260 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain | 0.56 | 42.0 | 3.09e-01 | 78.8% | 83.1% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.56 | 41.0 | 3.53e-01 | 76.5% | 79.2% |
| 6h5hA00 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.56 | 35.0 | 3.74e-01 | 71.8% | 74.6% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 48.0 | 3.67e-01 | 100.0% | 48.8% |
| 2b6cA02 | 1.25.40.290 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains | 0.55 | 45.0 | 4.34e-01 | 97.6% | 79.4% |
| 4fwvA02 | 1.20.120.1680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 43.0 | 3.75e-01 | 87.1% | 100.0% |
| 5jc3A02 | 1.20.1320.30 | Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › | 0.53 | 47.0 | 4.10e-01 | 96.5% | 77.0% |
| 8gr2A01 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.52 | 41.0 | 3.16e-01 | 84.7% | 36.9% |
| 2bgkA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.50 | 39.0 | 2.84e-01 | 87.1% | 31.5% |
| 1toaA01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.50 | 43.0 | 3.63e-01 | 95.3% | 79.7% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3585899 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.73 | 59.0 | 5.40e-01 | 87.1% | 84.5% |
| 3923407 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.71 | 60.0 | 5.47e-01 | 90.6% | 87.3% |
| 3739447 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.68 | 57.0 | 4.84e-01 | 100.0% | 55.7% |
| 3468208 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.67 | 56.0 | 5.12e-01 | 90.6% | 83.6% |
| 4547736 | 604.12.1.111 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27331 | 0.65 | 53.0 | 5.38e-01 | 90.6% | 98.8% |
| 3804380 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 57.0 | 3.32e-01 | 100.0% | 20.7% |
| 3260080 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.62 | 40.0 | 4.18e-01 | 85.9% | 70.0% |
| 3322007 | 601.1.2.8 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PGG | 0.62 | 44.0 | 3.54e-01 | 74.1% | 51.2% |
| 3256986 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.62 | 44.0 | 3.18e-01 | 74.1% | 73.3% |
| 3430765 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.62 | 42.0 | 4.03e-01 | 87.1% | 60.0% |
| 4879366 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.62 | 45.0 | 3.15e-01 | 77.6% | 29.1% |
| 3683169 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.62 | 42.0 | 4.06e-01 | 87.1% | 61.0% |
| 3938136 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.62 | 45.0 | 4.40e-01 | 89.4% | 70.5% |
| 4887090 | 3834.1.1.1 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA_TcB_BD | 0.61 | 42.0 | 2.78e-01 | 71.8% | 76.3% |
| 3917462 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.61 | 41.0 | 4.08e-01 | 89.4% | 65.6% |
| 3538008 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.60 | 40.0 | 3.99e-01 | 89.4% | 65.6% |
| 5034461 | 3930.1.1.3 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical | 0.59 | 52.0 | 4.58e-01 | 96.5% | 69.6% |
| 3785619 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.59 | 40.0 | 3.66e-01 | 70.6% | 96.5% |
| 4000500 | 109.4.1.1154 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS7_N | 0.57 | 50.0 | 3.10e-01 | 95.3% | 26.7% |
| 3933920 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.57 | 42.0 | 4.09e-01 | 87.1% | 70.5% |
| 3262453 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.57 | 48.0 | 3.47e-01 | 98.8% | 67.9% |
| 3233846 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.56 | 41.0 | 3.98e-01 | 87.1% | 69.5% |
| 3582688 | 109.4.1.1154 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS7_N | 0.56 | 48.0 | 3.69e-01 | 97.6% | 44.4% |
| 4962833 | 603.7.1.0 ↗ | alpha bundles › STAT-like › Ammonia monooxygenase subunit C › Ammonia monooxygenase subunit C | 0.55 | 47.0 | 3.73e-01 | 95.3% | 79.3% |
| 3249848 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.55 | 40.0 | 4.09e-01 | 87.1% | 78.8% |
| 4982137 | 4033.1.1.1 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N | 0.55 | 43.0 | 4.52e-01 | 98.8% | 97.3% |
| 3743981 | 5081.1.1.2 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 | 0.52 | 42.0 | 3.35e-01 | 90.6% | 65.3% |
| 3255436 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.52 | 40.0 | 4.10e-01 | 90.6% | 84.7% |
| 3277669 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.51 | 39.0 | 2.95e-01 | 85.9% | 74.2% |
| 3457383 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.51 | 38.0 | 3.76e-01 | 87.1% | 75.6% |
D2
medium
residues 1-57
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3njaA02 | 2.10.70.100 | Mainly Beta › Ribbon › Complement Module; domain 1 › | 0.66 | 33.0 | 3.59e-01 | 84.2% | 54.3% |
| 3lxrF00 | 1.10.4120.20 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › | 0.63 | 31.0 | 2.16e-01 | 70.2% | 13.3% |
| 3e07A00 | 2.10.90.10 | Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines | 0.60 | 43.0 | 3.66e-01 | 75.4% | 51.1% |
| 3gw6A03 | 3.30.2460.10 | Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Endo-n-acetylneuraminidase domain | 0.58 | 35.0 | 3.56e-01 | 86.0% | 57.9% |
| 4j5tA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.57 | 38.0 | 2.27e-01 | 70.2% | 20.1% |
| 3n77A00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.55 | 34.0 | 2.67e-01 | 94.7% | 25.5% |
| 1se8A02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.52 | 32.0 | 2.60e-01 | 86.0% | 32.4% |
| 1fm2B03 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.52 | 33.0 | 3.19e-01 | 86.0% | 53.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3935723 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.69 | 59.0 | 4.32e-01 | 93.0% | 53.8% |
| 4241211 | 375.1.1.204 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › PolC_DP2_central | 0.63 | 42.0 | 3.49e-01 | 70.2% | 65.7% |
| 3891521 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 44.0 | 2.85e-01 | 77.2% | 18.9% |
| 3662024 | 304.30.1.1 ↗ | a+b two layers › Alpha-beta plaits › D-ribose-5-phosphate isomerase (RpiA), lid domain › D-ribose-5-phosphate isomerase (RpiA), lid domain › Rib_5-P_isom_A | 0.61 | 39.0 | 3.46e-01 | 71.9% | 42.2% |
| 3566204 | 2003.1.5.69 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GCD14 | 0.55 | 43.0 | 2.86e-01 | 86.0% | 30.7% |
| 4961086 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.54 | 46.0 | 3.39e-01 | 100.0% | 54.9% |
| 3238872 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.54 | 32.0 | 2.35e-01 | 87.7% | 17.8% |
| 3898521 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.53 | 43.0 | 2.74e-01 | 100.0% | 98.6% |
| 5045394 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.53 | 45.0 | 3.34e-01 | 100.0% | 55.0% |
| 3641345 | 284.1.1.0 ↗ | a+b two layers › FKBP-like › FKBP-like › FKBP-like | 0.52 | 34.0 | 3.08e-01 | 70.2% | 47.5% |
| 3727030 | 11.1.5.20 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › NDT80_PhoG | 0.52 | 41.0 | 2.95e-01 | 94.7% | 75.5% |
| 4233683 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.51 | 33.0 | 2.34e-01 | 91.2% | 17.3% |
| 3588825 | 2004.1.1.552 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T4SS-DNA_transf, TraG-D_C | 0.50 | 40.0 | 2.39e-01 | 93.0% | 74.7% |
| 4087213 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.50 | 28.0 | 2.65e-01 | 73.7% | 34.7% |
| 3834595 | 328.12.1.1 ↗ | a+b two layers › IF3-like › IF3-like domain in Nudix hydrolase › IF3-like domain in Nudix hydrolase › Nudix_hydro | 0.50 | 34.0 | 2.60e-01 | 73.7% | 27.1% |
D3
medium
residues 58-204
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00078.33 best | RVT_1 | 30.6 | 4.30e-07 | 94.6% | 57.5% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z21A00 | 1.10.10.1000 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain | 0.53 | 27.0 | 3.25e-01 | 80.3% | 72.9% |
| 1xu0A00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.52 | 31.0 | 3.53e-01 | 78.9% | 80.4% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4434853 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.81 | 74.0 | 6.07e-01 | 98.0% | 57.9% |
| 3984781 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.79 | 71.0 | 6.94e-01 | 98.0% | 86.3% |
| 3968281 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.79 | 74.0 | 6.17e-01 | 98.0% | 68.1% |
| 3947863 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.78 | 72.0 | 5.86e-01 | 98.0% | 67.5% |
| 5078830 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.74 | 69.0 | 5.52e-01 | 98.0% | 61.5% |
| 3068775 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.73 | 67.0 | 5.94e-01 | 97.3% | 84.2% |
| 4890630 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 66.0 | 5.52e-01 | 98.0% | 66.5% |
| 4236458 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.66 | 60.0 | 4.63e-01 | 98.0% | 59.4% |
| 3242517 | 4009.1.1.3 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › KTI12 | 0.53 | 24.0 | 3.29e-01 | 77.6% | 84.0% |
| 4667226 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.52 | 36.0 | 3.12e-01 | 72.8% | 44.7% |
| 3225203 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.51 | 35.0 | 3.17e-01 | 70.7% | 89.5% |
D4
medium
residues 205-276
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2w01B00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.75 | 55.0 | 3.96e-01 | 77.8% | 46.2% |
| 2f1rA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 43.0 | 3.42e-01 | 75.0% | 75.7% |
| 1nxmA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.60 | 47.0 | 3.50e-01 | 86.1% | 55.2% |
| 5khaB01 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.60 | 43.0 | 2.96e-01 | 76.4% | 78.5% |
| 1mhyD00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.58 | 47.0 | 2.85e-01 | 90.3% | 54.3% |
| 1qmgB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 42.0 | 3.02e-01 | 79.2% | 40.7% |
| 2z86D02 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.57 | 41.0 | 2.84e-01 | 77.8% | 79.6% |
| 1ft8C01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.57 | 39.0 | 4.25e-01 | 87.5% | 96.4% |
| 4l80D00 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.56 | 44.0 | 2.90e-01 | 88.9% | 29.4% |
| 5oomK00 | 3.90.1180.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L13p; Chain: A; › Ribosomal protein L13 | 0.55 | 41.0 | 3.26e-01 | 84.7% | 67.8% |
| 4i9fA03 | 3.30.300.290 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.54 | 36.0 | 3.63e-01 | 72.2% | 79.2% |
| 5w0kA01 | 3.90.380.20 | Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II | 0.53 | 44.0 | 3.01e-01 | 100.0% | 87.4% |
| 3v7iA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.53 | 41.0 | 3.30e-01 | 84.7% | 66.7% |
| 1u6gC00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.53 | 37.0 | 2.04e-01 | 73.6% | 13.7% |
| 2wshA00 | 3.40.1440.40 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › | 0.51 | 36.0 | 2.92e-01 | 73.6% | 95.5% |
| 2dy1A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 38.0 | 2.62e-01 | 81.9% | 88.7% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3935908 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.77 | 61.0 | 5.11e-01 | 87.5% | 52.0% |
| 4126255 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.76 | 64.0 | 4.34e-01 | 95.8% | 36.0% |
| 3272304 | 304.36.1.2 ↗ | a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › RVT_1 | 0.73 | 57.0 | 4.57e-01 | 86.1% | 50.3% |
| 3600743 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.62 | 49.0 | 3.51e-01 | 87.5% | 40.4% |
| 3204533 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.62 | 43.0 | 4.29e-01 | 73.6% | 72.0% |
| 3995189 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.61 | 42.0 | 4.49e-01 | 84.7% | 86.7% |
| 4993067 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.61 | 44.0 | 3.45e-01 | 76.4% | 89.0% |
| 5032304 | 2004.1.1.97 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MobB | 0.60 | 43.0 | 3.05e-01 | 76.4% | 57.8% |
| 5064817 | 2004.1.1.97 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MobB | 0.59 | 43.0 | 3.46e-01 | 76.4% | 81.4% |
| 3779545 | 109.4.1.816 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RALGAPB_N | 0.57 | 40.0 | 2.58e-01 | 75.0% | 59.2% |
| 4377027 | 131.1.1.15 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › Ppx-GppA_III | 0.55 | 42.0 | 3.22e-01 | 86.1% | 65.4% |
| 3408055 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.54 | 42.0 | 3.97e-01 | 86.1% | 75.6% |
| 5082053 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 42.0 | 2.96e-01 | 91.7% | 92.7% |
| 3220364 | 6166.1.1.1 ↗ | alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 | 0.52 | 38.0 | 2.82e-01 | 77.8% | 56.5% |
| 4947457 | 2003.1.5.12 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase | 0.52 | 42.0 | 2.80e-01 | 91.7% | 70.2% |
| 4004145 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.50 | 39.0 | 2.86e-01 | 87.5% | 47.0% |