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IMGVR_UViG_3300018407_000144-3300018407-Ga0187900_100220313
Arc-VirIMGVR_UViG_3300018407_000144-3300018407-Ga0187900_100220313
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 18-113
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.69 | 41.0 | 4.66e-01 | 94.8% | 81.2% |
| 1uaaA02 | 1.10.10.160 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.61 | 37.0 | 4.12e-01 | 91.7% | 78.4% |
| 3pvlA03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.61 | 41.0 | 3.90e-01 | 85.4% | 56.8% |
| 3p5nA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.60 | 52.0 | 4.40e-01 | 97.9% | 79.2% |
| 3anpB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 44.0 | 3.47e-01 | 76.0% | 68.6% |
| 3ed5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.59 | 41.0 | 4.33e-01 | 90.6% | 82.1% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.59 | 44.0 | 4.58e-01 | 79.2% | 87.2% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 42.0 | 3.77e-01 | 75.0% | 89.9% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 43.0 | 3.86e-01 | 78.1% | 83.5% |
| 3iylB02 | 1.10.2050.10 | Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 | 0.58 | 40.0 | 3.67e-01 | 71.9% | 52.2% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.58 | 41.0 | 4.25e-01 | 88.5% | 78.9% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.57 | 41.0 | 3.69e-01 | 75.0% | 68.1% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.57 | 42.0 | 3.33e-01 | 77.1% | 68.3% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.57 | 43.0 | 4.38e-01 | 83.3% | 83.7% |
| 2g7lA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.45e-01 | 82.3% | 54.2% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 41.0 | 4.02e-01 | 77.1% | 79.4% |
| 2yguC00 | 1.10.238.190 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › | 0.55 | 38.0 | 3.57e-01 | 70.8% | 95.8% |
| 1w36F02 | 1.10.10.160 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.55 | 39.0 | 3.92e-01 | 75.0% | 100.0% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.55 | 38.0 | 3.87e-01 | 78.1% | 72.2% |
| 3l8kA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.54 | 38.0 | 2.97e-01 | 72.9% | 34.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 39.0 | 3.90e-01 | 76.0% | 95.1% |
| 1n00A03 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.54 | 29.0 | 3.25e-01 | 92.7% | 65.8% |
| 3llkA02 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.54 | 42.0 | 3.75e-01 | 85.4% | 94.4% |
| 1aisB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 34.0 | 3.47e-01 | 82.3% | 63.8% |
| 7m2wE01 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.54 | 46.0 | 3.31e-01 | 97.9% | 76.1% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 39.0 | 3.82e-01 | 77.1% | 79.0% |
| 4qlxB00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.53 | 44.0 | 3.50e-01 | 92.7% | 69.5% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 39.0 | 3.35e-01 | 77.1% | 49.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 39.0 | 3.86e-01 | 78.1% | 81.6% |
| 1e9rA02 | 1.10.8.80 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Magnesium chelatase subunit I, C-Terminal domain | 0.53 | 41.0 | 3.95e-01 | 97.9% | 72.6% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.52 | 39.0 | 3.82e-01 | 82.3% | 71.0% |
| 4ywoA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 37.0 | 2.98e-01 | 75.0% | 86.3% |
| 1by1A00 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.52 | 36.0 | 2.86e-01 | 71.9% | 76.1% |
| 1te2A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.51 | 31.0 | 3.54e-01 | 86.5% | 80.6% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.51 | 39.0 | 3.57e-01 | 81.2% | 78.7% |
| 3vkhA08 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 37.0 | 2.58e-01 | 77.1% | 25.9% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.51 | 39.0 | 3.93e-01 | 83.3% | 87.0% |
| 4ii2A02 | 3.40.50.12550 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2 | 0.51 | 44.0 | 3.42e-01 | 96.9% | 59.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.51 | 34.0 | 3.62e-01 | 76.0% | 77.6% |
| 1bdgA01 | 3.40.367.20 | Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › | 0.51 | 44.0 | 3.24e-01 | 100.0% | 79.6% |
| 3vkgA10 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 37.0 | 3.01e-01 | 78.1% | 46.9% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.50 | 37.0 | 3.52e-01 | 77.1% | 78.4% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4945244 | 608.1.1.0 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like | 0.67 | 56.0 | 4.32e-01 | 93.8% | 67.1% |
| 3715242 | 633.24.1.0 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain | 0.65 | 54.0 | 5.17e-01 | 96.9% | 79.1% |
| 3262205 | 633.24.1.0 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain | 0.65 | 52.0 | 5.32e-01 | 91.7% | 93.3% |
| 4221931 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.65 | 51.0 | 3.92e-01 | 85.4% | 90.7% |
| 3411080 | 603.1.1.101 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_6 | 0.64 | 47.0 | 3.39e-01 | 80.2% | 47.2% |
| 4939361 | 3896.1.2.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase | 0.63 | 49.0 | 4.31e-01 | 92.7% | 54.7% |
| 4014978 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 47.0 | 4.85e-01 | 79.2% | 84.4% |
| 3261117 | 633.24.1.2 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 | 0.60 | 52.0 | 5.23e-01 | 96.9% | 98.9% |
| 3411768 | 627.1.1.2 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › DUF5601 | 0.60 | 48.0 | 4.86e-01 | 89.6% | 86.3% |
| 3711705 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.60 | 44.0 | 4.57e-01 | 92.7% | 84.4% |
| 4004467 | 3457.1.1.1 ↗ | alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Peptidase_A24 | 0.59 | 43.0 | 3.74e-01 | 78.1% | 90.3% |
| 5055279 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.58 | 48.0 | 3.76e-01 | 89.6% | 73.7% |
| 3690080 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.58 | 41.0 | 3.86e-01 | 74.0% | 86.6% |
| 3968890 | 1075.1.1.12 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › CcmB | 0.58 | 49.0 | 3.87e-01 | 97.9% | 75.3% |
| 4058767 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.58 | 41.0 | 3.66e-01 | 74.0% | 73.6% |
| 3221654 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.58 | 45.0 | 3.87e-01 | 86.5% | 89.1% |
| 3625186 | 627.1.1.2 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › DUF5601 | 0.58 | 47.0 | 4.65e-01 | 88.5% | 87.0% |
| 4934635 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.57 | 48.0 | 3.58e-01 | 95.8% | 66.4% |
| 4034551 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.57 | 47.0 | 3.36e-01 | 93.8% | 75.2% |
| 3778624 | 627.1.1.0 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain | 0.57 | 48.0 | 4.77e-01 | 96.9% | 92.0% |
| 1019364 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 41.0 | 3.97e-01 | 77.1% | 76.6% |
| 3786841 | 101.1.2.392 ↗ | alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH | 0.56 | 43.0 | 4.20e-01 | 83.3% | 85.7% |
| 3925268 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 42.0 | 4.17e-01 | 82.3% | 76.0% |
| 3231735 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.56 | 44.0 | 3.66e-01 | 88.5% | 85.4% |
| 4983374 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.55 | 45.0 | 4.12e-01 | 89.6% | 88.5% |
| 3276672 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.55 | 41.0 | 3.71e-01 | 78.1% | 61.5% |
| 4977057 | 3960.1.1.0 ↗ | alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain | 0.55 | 40.0 | 3.86e-01 | 78.1% | 84.3% |
| 56928 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.55 | 44.0 | 4.18e-01 | 88.5% | 80.0% |
| 3954901 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.55 | 42.0 | 3.99e-01 | 84.4% | 68.3% |
| 4033204 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 44.0 | 3.45e-01 | 87.5% | 80.0% |
| 4960291 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.54 | 44.0 | 3.78e-01 | 89.6% | 78.7% |
| 3721641 | 5067.1.1.8 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › HPP | 0.54 | 46.0 | 3.88e-01 | 95.8% | 56.4% |
| 3439705 | 3758.1.1.7 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › BPS1 | 0.54 | 45.0 | 3.51e-01 | 93.8% | 83.6% |
| 3812703 | 3758.1.1.7 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › BPS1 | 0.53 | 44.0 | 3.39e-01 | 90.6% | 76.7% |
| 3236470 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.53 | 45.0 | 3.77e-01 | 95.8% | 88.0% |
| 3279601 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 41.0 | 3.48e-01 | 85.4% | 65.3% |
| 4956867 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.53 | 43.0 | 3.86e-01 | 90.6% | 92.9% |
| 1268387 | 604.1.1.6 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 | 0.53 | 39.0 | 3.77e-01 | 78.1% | 77.1% |
| 3726168 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 40.0 | 3.82e-01 | 81.2% | 80.0% |
| 2642997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 43.0 | 3.54e-01 | 95.8% | 94.8% |
| 3603451 | 601.7.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › HEPN domain in CRISPR-associated protein Csx1 | 0.52 | 36.0 | 3.46e-01 | 72.9% | 93.9% |
| 3189618 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 44.0 | 3.48e-01 | 100.0% | 88.0% |
| 3988387 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.51 | 38.0 | 3.82e-01 | 80.2% | 84.0% |
| 3972582 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.51 | 42.0 | 3.35e-01 | 90.6% | 77.0% |
| 3892492 | 604.1.1.66 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL | 0.50 | 36.0 | 3.52e-01 | 76.0% | 76.4% |
| 3855780 | 604.1.1.66 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL | 0.50 | 37.0 | 3.53e-01 | 78.1% | 73.0% |
| 4192201 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.50 | 36.0 | 3.08e-01 | 91.7% | 42.3% |
| 3929347 | 7579.1.1.70 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF1057 | 0.50 | 42.0 | 2.94e-01 | 93.8% | 27.8% |
| 3500905 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.50 | 35.0 | 3.29e-01 | 74.0% | 56.8% |