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IMGVR_UViG_3300018425_000138-3300018425-Ga0193580_10204731

Arc-Vir

IMGVR_UViG_3300018425_000138-3300018425-Ga0193580_10204731

Quality

79.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 365-412
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qenA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 50.0 4.52e-01 85.4% 61.4%
4jwoA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.66 57.0 4.12e-01 100.0% 89.4%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 44.0 3.23e-01 75.0% 81.0%
1zv1A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.58 38.0 3.61e-01 72.9% 54.2%
1zakA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 39.0 2.60e-01 75.0% 92.7%
2jrtA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 47.0 3.84e-01 95.8% 72.1%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.54 39.0 2.93e-01 75.0% 36.7%
2a3vB01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.51 43.0 3.54e-01 97.9% 67.0%
2w48B01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.51 37.0 3.68e-01 85.4% 78.8%
1l8qA03 1.10.1750.10 Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain 0.51 43.0 3.35e-01 95.8% 71.0%
2zttA00 6.10.140.720 Special › Helix non-globular › Helix Hairpins › 0.50 44.0 3.89e-01 100.0% 69.9%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5012367 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 56.0 5.37e-01 81.2% 61.8%
4938759 101.1.8.14 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › UPF0175 0.72 48.0 4.66e-01 81.2% 61.8%
4602458 4082.1.1.5 alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › PF27473 0.71 48.0 3.60e-01 70.8% 30.4%
5062514 101.1.1.371 alpha arrays › HTH › HTH › Three-helical HTH › UPF0175 0.67 57.0 5.91e-01 89.6% 95.6%
4965520 101.1.1.556 alpha arrays › HTH › HTH › Three-helical HTH › DUF7317 0.64 49.0 4.71e-01 85.4% 98.2%
4290973 3498.1.1.2 alpha arrays › RNA polymerase sigma factor rpoD N-terminal domain › RNA polymerase sigma factor rpoD N-terminal domain › RNA polymerase sigma factor rpoD N-terminal domain › Sigma70_r1_1 0.64 41.0 3.97e-01 75.0% 58.2%
5049179 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.62 46.0 4.29e-01 89.6% 63.3%
4937291 101.1.1.371 alpha arrays › HTH › HTH › Three-helical HTH › UPF0175 0.62 52.0 5.36e-01 91.7% 100.0%
4263447 3801.1.1.4 extended segments › ParE2-associated antitoxin 2 (PaaA2) › ParE2-associated antitoxin 2 (PaaA2) › ParE2-associated antitoxin 2 (PaaA2) › UPF0175 0.60 50.0 5.20e-01 91.7% 100.0%
4350602 101.1.8.14 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › UPF0175 0.58 48.0 4.37e-01 91.7% 69.2%
4970237 101.1.1.371 alpha arrays › HTH › HTH › Three-helical HTH › UPF0175 0.58 48.0 4.95e-01 97.9% 100.0%
4530329 101.1.8.14 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › UPF0175 0.58 48.0 4.47e-01 91.7% 73.3%
3452941 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.54 40.0 4.03e-01 83.3% 78.0%
3256356 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 41.0 3.86e-01 93.8% 100.0%
5004436 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 42.0 2.93e-01 100.0% 26.0%
D2 medium residues 12-70_192-218_279-299
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.59 36.0 4.09e-01 89.7% 84.2%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3287400 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.61 40.0 3.88e-01 99.1% 58.4%
3062952 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 36.0 3.71e-01 90.7% 66.3%
3278203 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.56 39.0 3.62e-01 100.0% 55.0%
3579266 5055.1.1.11 extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel › Cation_ATPase_N 0.54 34.0 3.95e-01 80.4% 89.3%
5042044 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.54 43.0 4.06e-01 98.1% 70.8%
3838953 2004.1.1.234 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrB_D3-like 0.52 43.0 3.07e-01 90.7% 89.0%
D3 medium residues 71-121_179-191
PDB
Domain cluster: representative
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kdrA02 3.40.140.120 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › 0.63 53.0 4.24e-01 93.8% 63.8%
3cu3A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 44.0 3.33e-01 79.7% 57.4%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.59 49.0 4.31e-01 87.5% 92.2%
3a76A01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 43.0 3.42e-01 79.7% 66.9%
3gwrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 43.0 3.49e-01 79.7% 75.6%
4hadB02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.56 41.0 2.97e-01 79.7% 86.2%
1o51A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 39.0 3.49e-01 75.0% 52.8%
2bhgA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.56 38.0 3.48e-01 73.4% 62.0%
3ktnA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.55 42.0 2.70e-01 84.4% 66.8%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 41.0 3.01e-01 82.8% 85.9%
5b55A01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 37.0 2.74e-01 71.9% 66.8%
3l4gC01 3.30.1370.240 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.55 44.0 3.83e-01 93.8% 79.0%
1whnA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 36.0 3.20e-01 70.3% 50.5%
3duwA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 39.0 2.79e-01 79.7% 72.6%
5hvqC01 3.90.1150.220 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.54 39.0 3.68e-01 78.1% 88.7%
2x8xX01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.54 45.0 4.31e-01 95.3% 96.1%
2ltsA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 36.0 3.32e-01 70.3% 81.4%
3wnkA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 42.0 2.71e-01 89.1% 33.0%
2b1xB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 40.0 2.98e-01 79.7% 78.4%
6hmjA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.53 38.0 3.37e-01 79.7% 81.0%
4k3bA05 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.53 44.0 4.20e-01 96.9% 97.5%
3gzrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 45.0 3.54e-01 96.9% 75.2%
4f7oA00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.53 42.0 2.92e-01 90.6% 52.3%
3bn7A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.14e-01 71.9% 54.9%
2nraC02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 43.0 3.78e-01 93.8% 72.5%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.40e-01 92.2% 56.8%
3kspA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 42.0 3.46e-01 92.2% 76.7%
4fidA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 40.0 2.92e-01 84.4% 83.4%
1xppD00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.52 39.0 3.41e-01 81.2% 57.4%
4ozjA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 37.0 3.17e-01 75.0% 82.7%
3p9aF00 1.10.132.80 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.52 39.0 3.24e-01 87.5% 79.1%
2ndpA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.52 36.0 3.15e-01 93.8% 47.5%
3l4gC04 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 42.0 2.85e-01 93.8% 55.5%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.08e-01 75.0% 83.2%
4as2A02 1.20.1440.310 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.51 35.0 3.05e-01 71.9% 60.2%
3blzA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 44.0 3.60e-01 100.0% 71.8%
4dg8A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.51 36.0 3.33e-01 98.4% 54.3%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.51 35.0 3.30e-01 75.0% 57.5%
4kt5C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 36.0 3.30e-01 76.6% 56.8%
2r5vB02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.51 35.0 2.59e-01 75.0% 92.8%
3ef8A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 36.0 2.95e-01 79.7% 62.2%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.51 35.0 3.29e-01 89.1% 56.0%
1kfiA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.51 37.0 3.04e-01 79.7% 76.8%
2raqA01 3.30.70.1340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › MTH889-like domain 0.50 34.0 3.20e-01 87.5% 54.1%
2j8aA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.50 39.0 3.61e-01 92.2% 65.5%
2pvpA02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.50 40.0 3.20e-01 93.8% 95.2%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5044372 1036.1.1.1 a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.69 50.0 4.26e-01 79.7% 90.0%
4863267 2.1.1.13 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-5a 0.62 39.0 3.82e-01 82.8% 55.6%
5075421 267.1.1.3 a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.62 45.0 3.06e-01 78.1% 94.2%
3164763 2004.1.1.99 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N 0.61 42.0 2.86e-01 73.4% 26.0%
4952373 325.1.2.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Molybdopterin synthase subunit MoaE › MoaE 0.60 42.0 3.30e-01 73.4% 70.3%
4933587 325.1.2.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Molybdopterin synthase subunit MoaE › MoaE 0.59 41.0 3.25e-01 73.4% 69.7%
3396918 372.2.1.1 a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.59 44.0 2.89e-01 79.7% 52.1%
361002 243.1.1.25 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_3 0.59 43.0 3.48e-01 79.7% 75.0%
5072384 325.1.2.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Molybdopterin synthase subunit MoaE › MoaE 0.58 41.0 3.25e-01 76.6% 68.0%
3415655 2492.1.1.4 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like 0.58 45.0 2.91e-01 87.5% 61.9%
3939348 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.57 38.0 3.26e-01 87.5% 40.0%
5030295 7515.1.1.6 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest 0.57 46.0 2.96e-01 90.6% 38.0%
4971395 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.57 39.0 3.56e-01 75.0% 63.2%
3954964 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.56 43.0 3.44e-01 87.5% 66.9%
5053325 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 38.0 3.27e-01 76.6% 41.8%
3575511 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.56 46.0 4.14e-01 95.3% 85.3%
4282602 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.56 39.0 3.56e-01 96.9% 53.3%
4011584 304.107.1.7 a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › POP1_N+POPLD 0.55 40.0 2.51e-01 79.7% 64.3%
5044942 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.55 37.0 3.23e-01 75.0% 42.9%
5021851 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.55 39.0 2.50e-01 76.6% 45.2%
5027690 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.55 38.0 3.23e-01 73.4% 53.6%
4984314 304.43.1.6 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 › FLAD1_M 0.54 38.0 3.41e-01 90.6% 52.2%
3844249 2004.1.1.47 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › G-alpha 0.54 43.0 2.95e-01 90.6% 66.9%
3703618 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.54 41.0 3.57e-01 87.5% 53.7%
4375028 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.54 38.0 3.08e-01 75.0% 97.6%
5074728 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.54 38.0 3.55e-01 92.2% 58.7%
4927291 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.54 41.0 3.73e-01 81.2% 98.8%
4042262 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 44.0 4.18e-01 98.4% 98.8%
1124104 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 44.0 4.20e-01 93.8% 100.0%
3707146 2004.1.1.17 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head 0.53 45.0 2.91e-01 100.0% 44.0%
3425342 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.53 39.0 3.77e-01 92.2% 68.0%
3296275 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 44.0 4.09e-01 96.9% 98.8%
3963877 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 44.0 4.24e-01 95.3% 100.0%
1247620 101.1.1.72 alpha arrays › HTH › HTH › Three-helical HTH › GP3_package 0.52 40.0 3.27e-01 89.1% 74.8%
3520104 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.52 44.0 4.14e-01 96.9% 98.8%
None 0.52 40.0 2.52e-01 85.9% 22.1%
3276185 2004.1.1.47 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › G-alpha 0.52 40.0 2.78e-01 85.9% 65.4%
3165534 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.52 42.0 4.10e-01 96.9% 100.0%
5047353 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.52 34.0 2.90e-01 73.4% 36.0%
4892175 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.51 44.0 3.55e-01 100.0% 74.8%
5047937 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 37.0 2.85e-01 78.1% 74.2%
4665957 305.1.1.0 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.51 36.0 3.10e-01 75.0% 61.0%
None 0.51 38.0 2.45e-01 85.9% 37.5%
3270988 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.50 38.0 2.76e-01 81.2% 47.7%
5025065 2004.1.1.100 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NTPase_1 0.50 39.0 2.91e-01 87.5% 43.9%
3970584 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.50 42.0 3.87e-01 96.9% 87.1%
3902399 810.1.1.3 a+b two layers › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › AIG2_2 0.50 37.0 2.79e-01 82.8% 61.7%
D4 medium residues 122-178
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ffgA00 3.30.720.20 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Protein of unknown function DUF1797 0.67 47.0 4.17e-01 73.7% 65.0%
1ugiD00 3.10.450.20 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor 0.62 47.0 4.26e-01 86.0% 93.9%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.60 39.0 3.69e-01 94.7% 53.5%
2jneA00 2.10.290.10 Mainly Beta › Ribbon › Rubredoxin-like › YfgJ-like 0.60 40.0 3.78e-01 70.2% 98.6%
6vilA01 2.30.30.490 Mainly Beta › Roll › SH3 type barrels. › Bromo adjacent homology (BAH) domain 0.59 44.0 3.38e-01 82.5% 64.1%
2xzmW01 3.10.290.10 Alpha Beta › Roll › Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A › RNA-binding S4 domain 0.58 45.0 3.67e-01 89.5% 67.8%
2uurA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.55 48.0 3.29e-01 100.0% 45.7%
4pkfB00 4.10.490.20 Few Secondary Structures › Irregular › High-Potential Iron-Sulfur Protein; Chain A › 0.55 38.0 3.56e-01 71.9% 60.9%
4dloB01 4.10.1240.10 Few Secondary Structures › Irregular › Hormone receptor fold › GPCR, family 2, extracellular hormone receptor domain 0.54 41.0 4.01e-01 86.0% 80.3%
2erfA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.52 46.0 3.12e-01 100.0% 45.0%
2yj6A02 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.52 39.0 3.41e-01 84.2% 72.6%
1ej6A04 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 40.0 2.77e-01 87.7% 50.4%
1vq8A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 36.0 3.37e-01 77.2% 70.5%
6ruiB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.51 42.0 3.43e-01 100.0% 74.6%
3kbgA01 3.10.290.10 Alpha Beta › Roll › Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A › RNA-binding S4 domain 0.51 39.0 3.68e-01 94.7% 96.3%
4xr7E01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 39.0 2.57e-01 89.5% 49.7%
3pg7A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 38.0 3.18e-01 86.0% 64.5%
1uurA04 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.50 36.0 2.88e-01 80.7% 38.3%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5036117 374.1.1.0 few secondary structure elements › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) 0.79 46.0 5.17e-01 73.7% 75.6%
3692657 4357.1.1.3 beta barrels › WWE domain › WWE domain › WWE domain › WWE_2 0.70 40.0 3.12e-01 73.7% 26.0%
3749834 64.1.1.0 beta meanders › WW domain-like › WW domain › WW domain 0.64 46.0 4.75e-01 78.9% 80.0%
3406773 241.10.1.1 a+b two layers › Type III secretory system chaperone-like › GAS2 domain › GAS2 domain › GAS2 0.63 50.0 4.76e-01 89.5% 77.1%
3874321 389.1.2.7 few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain › THBD 0.63 49.0 4.68e-01 87.7% 98.6%
3584223 5.1.5.64 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DCAF17 0.62 50.0 2.96e-01 91.2% 34.0%
3947082 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.62 52.0 4.57e-01 98.2% 91.1%
5030490 221.1.2.0 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif 0.61 47.0 3.81e-01 84.2% 71.8%
3574012 10.1.1.4 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin 0.60 42.0 3.17e-01 73.7% 53.8%
5069060 221.1.2.5 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4 0.60 45.0 4.00e-01 82.5% 87.1%
3935844 5.1.3.204 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF7911 0.60 50.0 3.17e-01 96.5% 80.6%
3383054 221.1.2.20 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › Ribosomal_S4e 0.59 36.0 4.10e-01 91.2% 97.1%
5049914 221.1.2.7 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › RS4NT 0.59 45.0 3.70e-01 84.2% 71.8%
4627769 221.1.2.5 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4 0.58 44.0 3.87e-01 84.2% 83.3%
3926511 5.1.5.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › CNH 0.58 43.0 2.84e-01 84.2% 29.8%
4966736 221.1.2.0 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif 0.58 44.0 3.93e-01 84.2% 88.2%
4889700 221.1.2.6 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4,RS4NT 0.58 44.0 3.62e-01 86.0% 65.0%
4179500 221.1.2.0 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif 0.57 44.0 3.62e-01 86.0% 69.1%
3468562 331.1.1.5 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › OGG_N 0.57 43.0 3.73e-01 82.5% 67.8%
2106030 221.1.2.6 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4,RS4NT 0.56 44.0 3.61e-01 89.5% 67.0%
3894532 10.1.1.0 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.56 50.0 3.42e-01 100.0% 49.2%
4945330 4294.1.1.11 few secondary structure elements › Trm112p-like › Trm112p-like › Trm112p-like › ResIII 0.56 42.0 3.99e-01 86.0% 67.1%
3356654 221.1.2.20 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › Ribosomal_S4e 0.56 39.0 3.97e-01 75.4% 94.5%
5005310 221.1.2.5 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4 0.56 44.0 3.62e-01 89.5% 72.7%
3543340 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.55 37.0 3.86e-01 71.9% 72.2%
3413447 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.55 36.0 3.73e-01 80.7% 72.7%
3909185 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.54 47.0 3.26e-01 100.0% 46.8%
3534125 10.1.1.0 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.54 47.0 3.18e-01 100.0% 43.6%
4114145 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.53 40.0 3.19e-01 86.0% 61.5%
3867404 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.51 37.0 3.72e-01 78.9% 75.0%
4671179 221.1.2.7 a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › RS4NT 0.51 39.0 3.31e-01 94.7% 70.8%
4662143 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.51 43.0 2.98e-01 100.0% 40.9%
3843142 376.1.1.5 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-UBP 0.51 35.0 2.71e-01 71.9% 78.5%
D5 medium residues 219-278
PDB
D6 medium residues 300-361
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.59 51.0 3.96e-01 100.0% 65.3%
3vs8H00 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.57 49.0 3.07e-01 100.0% 32.0%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.57 43.0 3.21e-01 82.3% 73.1%
3pf7B00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.56 48.0 2.90e-01 100.0% 66.0%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.56 33.0 3.05e-01 93.5% 45.6%
1br2A04 1.20.58.530 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 47.0 3.47e-01 98.4% 61.7%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3571382 2484.1.1.204 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27046, PF27073 0.65 54.0 3.18e-01 95.2% 21.0%
3644589 148.1.1.10 alpha arrays › Histone-like › Histone-related › Histone › TAFII28 0.64 49.0 4.21e-01 83.9% 59.0%
3670976 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.59 46.0 3.62e-01 88.7% 86.9%
4521994 5085.1.1.1 a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP 0.57 46.0 2.83e-01 90.3% 41.0%
3349382 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.55 45.0 3.59e-01 96.8% 49.0%
5014014 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.54 40.0 2.51e-01 82.3% 21.5%
4679608 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.53 41.0 2.72e-01 90.3% 56.1%
1282888 3828.1.1.1 a/b three-layered sandwiches › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavivirus non-structural protein 1 (NS1) a/b domain › Flavi_NS1 0.53 35.0 3.08e-01 88.7% 39.8%