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IMGVR_UViG_3300020438_002319-3300020438-Ga0211576_100156554

Arc-Vir

IMGVR_UViG_3300020438_002319-3300020438-Ga0211576_100156554

Quality

90.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-38
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.86 44.0 3.17e-01 88.9% 20.0%
4l8nA03 3.30.160.670 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.85 46.0 2.88e-01 100.0% 12.2%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 52.0 3.39e-01 94.4% 17.7%
3zf8A00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.77 45.0 2.57e-01 100.0% 6.9%
2oap202 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 52.0 3.05e-01 100.0% 9.4%
5cygB00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.76 50.0 2.95e-01 97.2% 8.9%
1u9pA00 1.10.1220.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like 0.70 48.0 3.52e-01 100.0% 27.1%
3rhtA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.69 51.0 3.14e-01 100.0% 12.3%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.68 50.0 4.24e-01 86.1% 48.3%
8eg0B01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.67 46.0 2.67e-01 75.0% 7.4%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.67 52.0 3.06e-01 94.4% 10.5%
1vq0A02 3.90.1280.10 Alpha Beta › Alpha-Beta Complex › CBS domain Like › HSP33 redox switch-like 0.66 49.0 4.36e-01 86.1% 59.6%
6nrzA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.66 53.0 3.03e-01 91.7% 16.3%
2qx2A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.65 51.0 3.02e-01 94.4% 11.0%
7mi4A01 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.64 49.0 3.25e-01 100.0% 18.5%
8d3mI01 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.64 49.0 3.20e-01 100.0% 17.4%
3weeB03 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.64 54.0 3.83e-01 100.0% 33.0%
7uqyB01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.64 47.0 2.99e-01 86.1% 47.2%
2nmlA00 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.64 51.0 3.77e-01 100.0% 33.0%
2pe4A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.63 48.0 2.77e-01 91.7% 8.6%
6aqgD02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.63 50.0 2.88e-01 91.7% 17.0%
3t5tB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.61 52.0 3.08e-01 97.2% 86.4%
1pc6A00 1.10.3790.10 Mainly Alpha › Orthogonal Bundle › NinB fold › NinB 0.61 44.0 3.02e-01 80.6% 95.7%
1oi2A02 3.30.1180.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › Dihydroxyacetone kinase; domain 2 0.61 44.0 2.87e-01 80.6% 54.9%
5eriA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 50.0 3.37e-01 97.2% 46.4%
3dsbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.61 42.0 3.23e-01 97.2% 28.7%
3nroA00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.60 48.0 2.96e-01 94.4% 82.6%
6s2wA01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.60 44.0 3.46e-01 91.7% 36.6%
3venA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 51.0 3.08e-01 97.2% 50.9%
1p4xA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 47.0 3.36e-01 97.2% 53.7%
7jgsG02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 45.0 3.38e-01 97.2% 32.7%
4arvA02 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.59 47.0 3.34e-01 97.2% 73.8%
2z86D02 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.59 46.0 2.86e-01 97.2% 34.6%
8agaA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 43.0 2.96e-01 80.6% 91.3%
1h0hB01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 3.24e-01 100.0% 78.0%
2ebnA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.57 49.0 2.87e-01 97.2% 22.5%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 43.0 2.89e-01 88.9% 82.4%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.57 48.0 3.51e-01 94.4% 77.7%
3lxqA01 3.30.1120.80 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.57 47.0 3.39e-01 91.7% 33.3%
2kqrA01 3.30.1910.20 Alpha Beta › 2-Layer Sandwich › so0334 like fold › asparaginyl-tRNA synthetase, N-terminal domain 0.57 43.0 3.52e-01 88.9% 97.3%
2j42A02 2.60.120.240 Mainly Beta › Sandwich › Jelly Rolls › Protective antigen, heptamerisation domain 0.57 42.0 2.73e-01 86.1% 45.9%
4c1sA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.56 48.0 2.74e-01 100.0% 90.7%
3obaA03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 46.0 2.74e-01 86.1% 61.2%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.55 41.0 3.29e-01 94.4% 39.1%
2qrdE01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.55 44.0 2.91e-01 100.0% 20.6%
8enbA01 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.54 37.0 2.98e-01 75.0% 60.2%
4rayA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.54 44.0 4.00e-01 91.7% 72.0%
2e9hA01 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.54 44.0 3.23e-01 100.0% 67.3%
1d7bA00 2.60.40.1210 Mainly Beta › Sandwich › Immunoglobulin-like › Cellobiose dehydrogenase, cytochrome domain 0.54 41.0 2.82e-01 100.0% 26.5%
2im9A02 2.30.260.10 Mainly Beta › Roll › putative xylanase like fold › putative xylanase like domain 0.53 39.0 2.81e-01 100.0% 61.9%
2dy1A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.53 45.0 3.56e-01 97.2% 84.2%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.51 38.0 2.48e-01 100.0% 62.8%
2bm0A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.51 42.0 3.74e-01 91.7% 66.7%
5r0dB01 2.60.34.20 Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › 0.51 35.0 2.69e-01 100.0% 91.6%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.50 42.0 2.58e-01 100.0% 31.9%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018603 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.83 50.0 2.97e-01 100.0% 9.6%
3627712 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.83 51.0 2.74e-01 97.2% 3.8%
3954346 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.80 50.0 2.90e-01 100.0% 7.5%
3180843 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.80 46.0 2.78e-01 100.0% 10.1%
3240369 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.75 57.0 3.36e-01 86.1% 41.1%
3892155 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.73 53.0 2.81e-01 77.8% 28.5%
3285877 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 50.0 3.05e-01 72.2% 46.7%
4239635 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.73 45.0 2.89e-01 94.4% 13.3%
5083528 101.1.11.0 alpha arrays › HTH › HTH › Ribbon-helix-helix 0.72 51.0 3.81e-01 97.2% 31.8%
4987009 3837.1.1.1 alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 0.72 50.0 3.30e-01 100.0% 18.0%
None 0.72 58.0 3.51e-01 100.0% 13.6%
5012106 101.1.2.25 alpha arrays › HTH › HTH › winged helix domain › FUR 0.71 50.0 3.32e-01 97.2% 20.0%
3204926 4099.1.1.3 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Spc24 0.71 50.0 3.98e-01 86.1% 38.6%
3924659 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.70 51.0 2.99e-01 80.6% 36.3%
3240740 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.65 50.0 3.15e-01 86.1% 15.9%
5075190 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.65 53.0 3.51e-01 100.0% 22.5%
3882804 263.1.1.4 a+b three layers › SRF-like › SRF-like › SRF-like › PRAS_NT 0.64 48.0 4.00e-01 83.3% 85.9%
3992658 5.1.4.149 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WDR54 0.64 49.0 3.08e-01 91.7% 32.7%
3797108 2008.1.1.29 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 0.63 47.0 3.01e-01 97.2% 15.6%
4004358 252.2.1.3 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_1 0.62 42.0 3.92e-01 75.0% 50.0%
3946510 803.1.1.0 a+b duplicates or obligate multimers › Hypothetical protein YoaG › Hypothetical protein YoaG › Hypothetical protein YoaG 0.62 44.0 4.25e-01 86.1% 64.4%
4025629 375.3.1.1 few secondary structure elements › Rubredoxin-like › CSL zinc finger › CSL zinc finger › zf-DNL 0.62 49.0 3.92e-01 100.0% 61.2%
4890984 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 47.0 3.46e-01 88.9% 52.9%
3929962 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.60 48.0 2.92e-01 91.7% 92.5%
4456198 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 47.0 3.05e-01 91.7% 51.9%
4987043 2002.1.1.73 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TGT 0.60 47.0 2.68e-01 86.1% 18.6%
3604748 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 50.0 3.08e-01 97.2% 40.9%
4028716 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.60 46.0 3.24e-01 91.7% 24.4%
5018200 2004.1.1.220 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 0.59 47.0 2.66e-01 100.0% 48.9%
3480321 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 45.0 3.73e-01 91.7% 44.2%
3307706 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.59 44.0 3.09e-01 88.9% 22.9%
5049962 1144.1.1.1 beta sandwiches › Apc (acetophenone carboxylase) beta subunit C-terminal domain › Apc (acetophenone carboxylase) beta subunit C-terminal domain › Apc (acetophenone carboxylase) beta subunit C-terminal domain › Hydantoinase_B 0.59 48.0 2.84e-01 97.2% 16.6%
4583844 327.16.1.7 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › Rhomboid_N 0.59 39.0 3.23e-01 86.1% 32.3%
3498497 301.7.1.0 a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like 0.59 46.0 2.86e-01 88.9% 19.1%
3899209 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.59 49.0 3.12e-01 97.2% 49.2%
3926007 7568.1.1.0 a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.59 48.0 3.45e-01 94.4% 86.7%
3593736 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.58 51.0 3.74e-01 100.0% 36.0%
3512976 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.58 43.0 2.57e-01 80.6% 75.8%
3746945 5051.1.1.1 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SNF 0.58 47.0 2.61e-01 94.4% 48.2%
3408042 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 45.0 2.58e-01 88.9% 8.5%
3492270 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.57 45.0 3.02e-01 100.0% 30.3%
3617650 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 46.0 2.88e-01 100.0% 32.5%
3260134 622.4.1.61 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Mit_KHE1 0.57 48.0 3.24e-01 97.2% 57.2%
3818705 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.57 46.0 3.60e-01 94.4% 63.7%
3703262 226.1.1.1 a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.57 44.0 3.41e-01 100.0% 83.8%
4417105 2004.1.1.77 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87,HerA_C 0.57 48.0 2.73e-01 97.2% 9.3%
4959999 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.56 39.0 3.73e-01 75.0% 60.0%
3630540 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.56 48.0 2.87e-01 100.0% 27.5%
4029085 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.56 45.0 3.14e-01 100.0% 34.3%
3274487 605.1.1.155 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Gpi1 0.56 45.0 2.90e-01 91.7% 19.4%
3415555 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.55 49.0 2.84e-01 100.0% 17.6%
4303957 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.55 44.0 3.05e-01 100.0% 25.8%
3667109 101.1.2.111 alpha arrays › HTH › HTH › winged helix domain › RQC 0.55 48.0 3.24e-01 97.2% 35.2%
3280900 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.55 43.0 2.93e-01 88.9% 65.3%
3934910 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.54 38.0 2.48e-01 88.9% 13.9%
4024971 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.54 42.0 3.67e-01 86.1% 56.4%
4096542 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.54 41.0 3.64e-01 86.1% 56.4%
3795565 174.1.1.14 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › NKAIN 0.54 42.0 2.73e-01 91.7% 38.3%
4403587 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.54 41.0 3.14e-01 86.1% 36.5%
3901808 5051.1.1.1 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SNF 0.53 49.0 2.64e-01 100.0% 36.2%
3656521 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.52 45.0 3.32e-01 97.2% 62.1%
4342292 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.52 40.0 3.52e-01 86.1% 56.4%
4153200 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.52 47.0 3.03e-01 100.0% 24.0%
4242930 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.52 39.0 2.99e-01 86.1% 34.4%
5073703 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.52 39.0 3.56e-01 83.3% 78.0%
4284613 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.52 39.0 3.11e-01 86.1% 39.7%
5006512 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.51 41.0 3.52e-01 91.7% 53.3%
4982318 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.51 45.0 3.82e-01 100.0% 70.0%
4991835 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.51 37.0 3.50e-01 88.9% 64.0%
D2 high residues 51-118
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.75 51.0 5.19e-01 77.9% 71.6%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 48.0 4.06e-01 72.1% 42.7%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 46.0 4.49e-01 76.5% 64.4%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 50.0 4.87e-01 77.9% 84.2%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.66 50.0 5.12e-01 89.7% 84.6%
1pduA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.66 48.0 3.27e-01 76.5% 42.2%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 45.0 4.29e-01 72.1% 62.5%
3wurA00 1.20.1420.60 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › 0.65 49.0 3.73e-01 82.4% 67.3%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 47.0 4.82e-01 79.4% 81.2%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.64 37.0 4.24e-01 89.7% 78.4%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 48.0 4.77e-01 91.2% 77.5%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.63 41.0 3.94e-01 95.6% 58.4%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.62 47.0 2.93e-01 80.9% 18.8%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.62 51.0 4.57e-01 86.8% 90.1%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 43.0 4.08e-01 76.5% 61.7%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.61 44.0 4.33e-01 76.5% 73.6%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.61 40.0 4.12e-01 70.6% 71.9%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.61 46.0 3.89e-01 80.9% 62.5%
2id3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 46.0 3.67e-01 82.4% 85.9%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 45.0 4.33e-01 92.6% 70.1%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 50.0 3.95e-01 92.6% 55.7%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.60 42.0 4.31e-01 85.3% 80.0%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.59 44.0 4.45e-01 80.9% 91.4%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 44.0 4.25e-01 82.4% 70.5%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 4.82e-01 91.2% 88.4%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.58 39.0 4.16e-01 75.0% 82.8%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 42.0 3.69e-01 82.4% 53.4%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 4.16e-01 91.2% 86.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.57 49.0 4.23e-01 91.2% 60.8%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.56 41.0 3.99e-01 94.1% 70.3%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.56 43.0 4.02e-01 80.9% 74.1%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.56 50.0 3.79e-01 97.1% 42.6%
1grjA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.56 46.0 4.47e-01 92.6% 82.4%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 47.0 3.01e-01 92.6% 68.6%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.56 50.0 4.55e-01 98.5% 94.4%
3cb2A03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.56 43.0 4.51e-01 98.5% 91.8%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.56 49.0 4.64e-01 95.6% 88.7%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.55 46.0 4.11e-01 89.7% 94.7%
4a18Q01 1.10.10.1760 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L36 0.55 42.0 4.24e-01 83.8% 94.2%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 46.0 3.68e-01 91.2% 46.6%
1rv2D04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.55 41.0 4.12e-01 94.1% 78.6%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.54 47.0 4.12e-01 95.6% 64.7%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 44.0 3.49e-01 89.7% 79.0%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 43.0 3.44e-01 89.7% 76.2%
1hdlA00 3.30.60.30 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.53 39.0 4.10e-01 89.7% 98.2%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 44.0 3.01e-01 100.0% 60.1%
3rpmA02 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.53 36.0 3.42e-01 76.5% 56.5%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 45.0 3.66e-01 98.5% 66.7%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.53 42.0 4.32e-01 94.1% 91.0%
6bz0D01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 40.0 2.71e-01 79.4% 27.0%
4iw9A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 44.0 3.71e-01 95.6% 72.6%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.50 40.0 3.58e-01 88.2% 80.8%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.50 41.0 4.14e-01 97.1% 100.0%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4206858 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.72 47.0 3.91e-01 72.1% 40.0%
3944950 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 46.0 4.69e-01 82.4% 72.3%
4621241 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.67 46.0 3.19e-01 70.6% 42.3%
5009597 7014.1.1.0 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain 0.67 50.0 4.29e-01 80.9% 82.7%
4982611 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.65 47.0 3.70e-01 82.4% 36.7%
4401282 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.64 44.0 3.71e-01 72.1% 43.5%
3941235 4992.1.1.0 extended segments › RelB-like › RelB-like › RelB-like 0.64 46.0 4.12e-01 76.5% 56.8%
3449724 603.1.1.155 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › EDS1_EP 0.64 54.0 4.62e-01 100.0% 71.7%
3400801 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 47.0 3.69e-01 77.9% 60.0%
3596744 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 50.0 4.68e-01 94.1% 69.4%
5039854 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 46.0 4.44e-01 76.5% 72.0%
4974436 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.62 53.0 3.87e-01 95.6% 95.3%
2799599 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 44.0 4.10e-01 76.5% 59.3%
3682662 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.62 52.0 4.32e-01 98.5% 98.5%
3556539 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.61 51.0 4.03e-01 91.2% 62.9%
5004728 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.61 43.0 3.80e-01 75.0% 52.0%
3685761 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.61 48.0 2.98e-01 91.2% 16.4%
3617959 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 44.0 3.85e-01 77.9% 55.3%
3642640 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.60 51.0 3.30e-01 94.1% 57.4%
3862115 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 52.0 4.53e-01 98.5% 81.9%
4165638 3455.1.1.0 alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.58 41.0 4.46e-01 75.0% 90.9%
4015803 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 52.0 3.45e-01 100.0% 27.0%
3494616 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.58 46.0 4.32e-01 89.7% 84.7%
4964836 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.57 44.0 3.40e-01 86.8% 72.9%
4024515 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.57 48.0 3.79e-01 97.1% 49.7%
3921192 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 43.0 3.67e-01 83.8% 89.6%
3705393 3636.1.1.1 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain › HBB 0.56 44.0 4.00e-01 95.6% 62.1%
3733194 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 49.0 3.17e-01 100.0% 22.4%
4843075 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.55 48.0 4.23e-01 95.6% 69.8%
3481310 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.54 44.0 3.99e-01 86.8% 73.3%
4964814 2007.1.3.72 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › HalX 0.54 44.0 3.36e-01 92.6% 73.1%
4110261 3748.1.1.2 extended segments › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › CSN5_C 0.53 46.0 4.26e-01 94.1% 76.5%
4038778 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.53 43.0 3.65e-01 92.6% 53.0%
3591815 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.53 45.0 4.42e-01 97.1% 93.3%
4872781 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.53 47.0 3.98e-01 100.0% 67.5%
4934026 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.52 44.0 4.53e-01 100.0% 100.0%
2857735 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.52 46.0 4.15e-01 100.0% 79.4%
5029513 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.52 44.0 4.39e-01 97.1% 92.9%
D3 high residues 125-186
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zbsA03 1.10.720.160 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.56 43.0 3.91e-01 88.7% 98.9%
3mdqA02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.54 43.0 3.13e-01 90.3% 47.1%
3h5qA03 3.90.1170.30 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Pyrimidine nucleoside phosphorylase-like, C-terminal domain 0.53 40.0 3.63e-01 88.7% 83.9%
7ahdC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 38.0 2.63e-01 85.5% 36.5%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4974457 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.60 50.0 3.50e-01 96.8% 74.1%
85098 325.1.3.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Pyrimidine nucleoside phosphorylase C-terminal domain 0.57 44.0 3.80e-01 87.1% 75.2%
4947345 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.54 37.0 3.40e-01 72.6% 76.7%
4431446 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.54 37.0 2.75e-01 71.0% 56.4%
5081333 304.8.1.4 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.54 39.0 3.71e-01 79.0% 82.7%
3242580 377.11.1.1 few secondary structure elements › Glucocorticoid receptor-like › THAP domain › THAP domain › THAP 0.52 38.0 3.68e-01 83.9% 68.5%