←Back to structures
IMGVR_UViG_3300020454_001918-3300020454-Ga0211548_100008344
Arc-VirIMGVR_UViG_3300020454_001918-3300020454-Ga0211548_100008344
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-71
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.77 | 62.0 | 6.14e-01 | 88.7% | 96.1% |
| 3q8dA02 | 1.20.1440.120 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Recombination protein O, C-terminal domain | 0.73 | 60.0 | 4.67e-01 | 90.1% | 57.8% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.73 | 62.0 | 5.96e-01 | 95.8% | 100.0% |
| 7kfuC02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.70 | 60.0 | 4.25e-01 | 100.0% | 39.9% |
| 1td6A03 | 1.10.472.40 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 | 0.69 | 58.0 | 5.29e-01 | 91.5% | 72.8% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 61.0 | 5.83e-01 | 100.0% | 100.0% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 59.0 | 5.69e-01 | 95.8% | 95.1% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 55.0 | 4.96e-01 | 91.5% | 89.3% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 55.0 | 3.72e-01 | 87.3% | 37.0% |
| 1k32A03 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.67 | 54.0 | 5.46e-01 | 91.5% | 94.4% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.67 | 55.0 | 4.77e-01 | 94.4% | 66.1% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 58.0 | 4.97e-01 | 100.0% | 84.7% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.65 | 55.0 | 5.27e-01 | 93.0% | 90.1% |
| 2g8lA02 | 1.10.285.20 | Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 | 0.65 | 50.0 | 5.17e-01 | 91.5% | 90.8% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 49.0 | 4.83e-01 | 84.5% | 87.3% |
| 6k9pB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.64 | 55.0 | 4.28e-01 | 95.8% | 78.9% |
| 7b7tA01 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 52.0 | 4.07e-01 | 93.0% | 96.3% |
| 4fjvA02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.62 | 53.0 | 4.23e-01 | 95.8% | 77.8% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 50.0 | 5.00e-01 | 90.1% | 92.0% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.62 | 51.0 | 4.35e-01 | 94.4% | 76.6% |
| 1fc6A01 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.62 | 49.0 | 4.46e-01 | 95.8% | 64.3% |
| 2gfhA02 | 1.20.120.710 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain | 0.62 | 45.0 | 4.29e-01 | 78.9% | 84.9% |
| 2vf1A04 | 1.20.140.120 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.62 | 47.0 | 3.61e-01 | 81.7% | 73.2% |
| 2juaA00 | 1.20.1480.30 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein | 0.61 | 51.0 | 4.64e-01 | 95.8% | 75.5% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 51.0 | 4.46e-01 | 90.1% | 81.4% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.60 | 49.0 | 4.39e-01 | 94.4% | 79.6% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.60 | 52.0 | 4.15e-01 | 97.2% | 75.2% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 45.0 | 4.27e-01 | 83.1% | 81.2% |
| 2wl8C00 | 1.20.120.900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain | 0.58 | 43.0 | 3.79e-01 | 80.3% | 72.5% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 46.0 | 4.17e-01 | 88.7% | 76.0% |
| 4h8aB01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.57 | 42.0 | 4.44e-01 | 87.3% | 95.0% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.56 | 45.0 | 4.28e-01 | 93.0% | 94.3% |
| 4ol9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 48.0 | 4.03e-01 | 98.6% | 100.0% |
| 2k5gA01 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.56 | 38.0 | 2.93e-01 | 71.8% | 41.7% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 46.0 | 3.92e-01 | 100.0% | 98.5% |
| 4nqwA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.56 | 45.0 | 4.30e-01 | 93.0% | 98.8% |
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.55 | 37.0 | 3.47e-01 | 71.8% | 54.3% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.55 | 41.0 | 3.95e-01 | 85.9% | 79.5% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.54 | 46.0 | 3.68e-01 | 91.5% | 53.8% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.52 | 41.0 | 4.00e-01 | 90.1% | 83.5% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 38.0 | 2.97e-01 | 77.5% | 42.4% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1487359 | 611.11.1.1 ↗ | alpha bundles › N-cbl like › Plasmodium host cell traversal protein SPECT1 › Plasmodium host cell traversal protein SPECT1 › SPECT1 | 0.78 | 70.0 | 5.19e-01 | 100.0% | 74.6% |
| 4993602 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.75 | 59.0 | 6.18e-01 | 83.1% | 93.7% |
| 4017447 | 3567.1.1.51 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin | 0.74 | 65.0 | 4.86e-01 | 100.0% | 66.7% |
| 5061328 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.72 | 60.0 | 6.09e-01 | 93.0% | 100.0% |
| 4946843 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.72 | 58.0 | 6.03e-01 | 87.3% | 100.0% |
| 5066642 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.70 | 59.0 | 5.95e-01 | 93.0% | 95.7% |
| 3967936 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.68 | 53.0 | 5.21e-01 | 84.5% | 85.3% |
| 3420431 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.68 | 59.0 | 5.56e-01 | 97.2% | 90.6% |
| 5013293 | 5051.1.1.3 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF | 0.67 | 55.0 | 3.36e-01 | 95.8% | 18.2% |
| 54604 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.66 | 55.0 | 4.72e-01 | 94.4% | 66.1% |
| 3984588 | 4044.1.1.1 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane | 0.66 | 58.0 | 4.78e-01 | 100.0% | 60.0% |
| 3272974 | 601.7.1.21 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NICE-3 | 0.66 | 50.0 | 4.48e-01 | 81.7% | 86.0% |
| 3805676 | 1128.1.1.13 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › PF30094 | 0.66 | 56.0 | 5.20e-01 | 95.8% | 82.2% |
| 3888928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 54.0 | 5.22e-01 | 93.0% | 92.5% |
| 3987813 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.65 | 50.0 | 4.91e-01 | 84.5% | 78.7% |
| 5061323 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.64 | 51.0 | 5.27e-01 | 87.3% | 100.0% |
| 5031855 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.64 | 53.0 | 5.14e-01 | 93.0% | 100.0% |
| 4955005 | 7583.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › ARMT1-like_dom | 0.63 | 50.0 | 3.64e-01 | 91.5% | 29.8% |
| 4034431 | 632.15.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN | 0.63 | 53.0 | 5.06e-01 | 94.4% | 89.3% |
| 3454977 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.63 | 55.0 | 4.46e-01 | 98.6% | 83.0% |
| 4955523 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.62 | 51.0 | 4.42e-01 | 93.0% | 81.7% |
| 3603512 | 633.5.1.1 ↗ | alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA | 0.62 | 54.0 | 4.35e-01 | 100.0% | 56.6% |
| 3910005 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.62 | 51.0 | 3.46e-01 | 97.2% | 35.5% |
| 3989722 | 632.24.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor C-terminal domain › GBS CAMP factor C-terminal domain | 0.62 | 47.0 | 4.82e-01 | 83.1% | 98.5% |
| 3603720 | 2006.1.3.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain | 0.61 | 46.0 | 3.48e-01 | 83.1% | 31.1% |
| 5070580 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.61 | 45.0 | 4.81e-01 | 83.1% | 100.0% |
| 3865887 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.60 | 51.0 | 4.80e-01 | 93.0% | 92.9% |
| 3980912 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 52.0 | 4.47e-01 | 98.6% | 73.9% |
| 4144086 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.59 | 45.0 | 4.06e-01 | 83.1% | 70.0% |
| 3334314 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.57 | 50.0 | 3.81e-01 | 100.0% | 74.7% |
| 3494901 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 48.0 | 3.96e-01 | 100.0% | 81.4% |
| 3960310 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.56 | 43.0 | 4.39e-01 | 88.7% | 94.3% |
| 4118286 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.55 | 42.0 | 4.07e-01 | 87.3% | 77.6% |
| 4164998 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.54 | 41.0 | 3.74e-01 | 84.5% | 72.0% |
| 3266119 | 135.1.1.1 ↗ | alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha | 0.53 | 47.0 | 3.99e-01 | 100.0% | 65.0% |
D2
high
residues 122-212_241-365
Domain cluster:
rep: OQ417966.1__WJJ55912.1__PROPHIT361_108__00108__D15-81_130-142_243-343
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00005.34 best | ABC_tran | 83.4 | 3.20e-23 | 59.7% | 97.8% |