←Back to structures
IMGVR_UViG_3300021255_003095-3300021255-Ga0223825_1010595139
Arc-VirIMGVR_UViG_3300021255_003095-3300021255-Ga0223825_1010595139
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 13-177
Domain cluster:
rep: rifcsphigho2_12_scaffold_16_prodigal-single.1__X__X__00427__D428-563_922-933
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 63.6 | 2.30e-17 | 98.2% | 42.2% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qv6B02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.70 | 33.0 | 3.84e-01 | 100.0% | 59.8% |
| 1ghhA00 | 3.30.910.10 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › DinI-like | 0.64 | 30.0 | 4.15e-01 | 96.4% | 88.9% |
| 3ncvA02 | 3.30.1370.100 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › MutL, C-terminal domain, regulatory subdomain | 0.63 | 25.0 | 3.37e-01 | 94.5% | 65.9% |
| 2ebbA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.63 | 29.0 | 3.69e-01 | 95.8% | 71.9% |
| 2yweA03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.62 | 27.0 | 3.62e-01 | 100.0% | 76.8% |
| 1azsA00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.60 | 35.0 | 3.33e-01 | 100.0% | 47.9% |
| 3im8A02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.58 | 23.0 | 3.37e-01 | 100.0% | 80.8% |
| 1sqgA03 | 3.30.70.1170 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 | 0.58 | 21.0 | 3.39e-01 | 98.8% | 91.4% |
| 2rhqB01 | 3.30.56.10 | Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › | 0.57 | 25.0 | 3.68e-01 | 97.6% | 95.7% |
| 1b7yB01 | 3.30.56.10 | Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › | 0.57 | 25.0 | 3.73e-01 | 99.4% | 95.7% |
| 1p5dX04 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.55 | 30.0 | 3.89e-01 | 100.0% | 95.7% |
| 2zbiA02 | 3.30.70.2120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 28.0 | 3.35e-01 | 100.0% | 78.9% |
| 4g6tA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.51 | 24.0 | 2.75e-01 | 100.0% | 55.5% |
| 2jpfA01 | 1.20.58.960 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Protein of unknown function (DUF3120) | 0.51 | 23.0 | 3.12e-01 | 76.4% | 80.5% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5025843 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.83 | 65.0 | 5.91e-01 | 100.0% | 62.9% |
| 3968795 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.81 | 78.0 | 6.44e-01 | 100.0% | 63.3% |
| 3993981 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.80 | 76.0 | 6.69e-01 | 100.0% | 72.9% |
| 4932480 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.79 | 73.0 | 6.47e-01 | 100.0% | 71.4% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.79 | 75.0 | 4.84e-01 | 100.0% | 30.2% |
| 3597965 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.78 | 74.0 | 6.37e-01 | 100.0% | 73.9% |
| 4942685 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.77 | 74.0 | 5.11e-01 | 100.0% | 34.6% |
| 5025209 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.77 | 74.0 | 6.43e-01 | 100.0% | 71.1% |
| 4958554 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.77 | 74.0 | 6.42e-01 | 100.0% | 74.0% |
| 4939489 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.77 | 56.0 | 5.26e-01 | 100.0% | 63.1% |
| 5017083 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 73.0 | 6.02e-01 | 100.0% | 66.7% |
| 4977732 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.76 | 70.0 | 6.15e-01 | 100.0% | 69.6% |
| 5044377 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 72.0 | 6.18e-01 | 100.0% | 68.2% |
| 5041308 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.73 | 70.0 | 5.78e-01 | 100.0% | 61.1% |
| 3603883 | 304.48.1.22 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III | 0.70 | 34.0 | 3.77e-01 | 100.0% | 56.9% |
| 4944833 | 304.48.1.31 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 | 0.70 | 38.0 | 3.70e-01 | 100.0% | 47.2% |
| 5039148 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.69 | 29.0 | 4.52e-01 | 94.5% | 100.0% |
| 4977412 | 304.48.1.22 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III | 0.68 | 34.0 | 3.93e-01 | 100.0% | 64.2% |
| 5031058 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.68 | 30.0 | 4.50e-01 | 95.2% | 97.1% |
| 3962249 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.66 | 27.0 | 4.25e-01 | 96.4% | 96.9% |
| 3710757 | 304.163.1.1 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 | 0.66 | 27.0 | 4.02e-01 | 100.0% | 88.6% |
| 3699931 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.62 | 32.0 | 3.17e-01 | 100.0% | 45.0% |
| 4978280 | 304.19.1.1 ↗ | a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha | 0.61 | 31.0 | 4.05e-01 | 100.0% | 90.5% |
| 4449508 | 331.2.1.13 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › DinI | 0.61 | 30.0 | 4.10e-01 | 96.4% | 95.0% |
| 3715563 | 304.163.1.1 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 | 0.61 | 26.0 | 3.71e-01 | 100.0% | 88.6% |
| 3597641 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.61 | 27.0 | 3.74e-01 | 100.0% | 86.7% |
| 4611955 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.61 | 35.0 | 3.28e-01 | 100.0% | 44.9% |
| 4144335 | 304.48.1.24 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 | 0.60 | 55.0 | 4.75e-01 | 100.0% | 66.9% |
| 3959605 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.60 | 35.0 | 4.01e-01 | 100.0% | 76.0% |
| 3386797 | 4964.1.1.1 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A | 0.58 | 54.0 | 4.89e-01 | 100.0% | 89.7% |
| 4995088 | 873.1.1.0 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain | 0.58 | 32.0 | 3.42e-01 | 83.6% | 60.7% |
| 3996298 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.58 | 26.0 | 3.62e-01 | 100.0% | 85.0% |
| 3950698 | 304.48.1.4 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc | 0.58 | 35.0 | 3.17e-01 | 100.0% | 44.1% |
| 3284790 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.57 | 29.0 | 3.98e-01 | 97.0% | 100.0% |
| 4649320 | 101.1.9.0 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain | 0.56 | 26.0 | 3.64e-01 | 98.8% | 92.0% |
| 3390067 | 101.1.9.5 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 | 0.55 | 26.0 | 3.47e-01 | 98.8% | 83.5% |
| 5036416 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.55 | 26.0 | 3.46e-01 | 96.4% | 84.7% |
D2
high
residues 209-342
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fxdA06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.76 | 70.0 | 6.61e-01 | 99.3% | 89.4% |
| 1tgoA05 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.76 | 70.0 | 6.50e-01 | 100.0% | 82.6% |
| 3iayA07 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.74 | 67.0 | 6.47e-01 | 99.3% | 89.5% |
| 1k78I00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 29.0 | 4.24e-01 | 95.5% | 93.1% |
| 5xs2B02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 34.0 | 3.50e-01 | 100.0% | 52.3% |
| 2oxlA00 | 1.20.5.5260 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.63 | 31.0 | 4.19e-01 | 94.0% | 96.8% |
| 2vk9A04 | 1.10.274.80 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.62 | 32.0 | 3.60e-01 | 96.3% | 61.5% |
| 4mspB02 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.57 | 25.0 | 3.18e-01 | 90.3% | 68.0% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4978606 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.77 | 70.0 | 6.63e-01 | 97.0% | 92.3% |
| 5058883 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.76 | 68.0 | 6.50e-01 | 96.3% | 89.7% |
| 5044378 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.76 | 70.0 | 6.72e-01 | 99.3% | 95.3% |
| 3597971 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.75 | 68.0 | 6.17e-01 | 98.5% | 78.9% |
| 4547010 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.75 | 68.0 | 6.16e-01 | 98.5% | 78.9% |
| 3932319 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.75 | 34.0 | 4.03e-01 | 93.3% | 61.1% |
| 5025210 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.73 | 67.0 | 6.43e-01 | 98.5% | 91.3% |
| 5031722 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.73 | 67.0 | 6.31e-01 | 99.3% | 84.4% |
| 5069335 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.73 | 67.0 | 6.37e-01 | 98.5% | 91.0% |
| 3622919 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.73 | 34.0 | 4.34e-01 | 100.0% | 75.0% |
| 4956225 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.72 | 66.0 | 6.41e-01 | 98.5% | 91.7% |
| 3797774 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.71 | 64.0 | 6.22e-01 | 96.3% | 92.4% |
| None | — | 0.63 | 28.0 | 4.11e-01 | 78.4% | 100.0% | |
| 3509156 | 101.1.2.352 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_Tnp_Tc5 | 0.62 | 33.0 | 4.28e-01 | 94.0% | 95.7% |
| 3781946 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.62 | 30.0 | 4.03e-01 | 94.0% | 92.3% |
| 3922168 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.59 | 30.0 | 3.85e-01 | 96.3% | 90.0% |
| 4019914 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.58 | 30.0 | 3.73e-01 | 94.0% | 85.3% |
| 2779106 | 864.1.1.1 ↗ | a+b two layers › DLC › DLC › DLC › Dynein_light | 0.53 | 34.0 | 3.69e-01 | 100.0% | 78.4% |
| 3563314 | 190.1.1.1 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box | 0.52 | 36.0 | 4.04e-01 | 82.8% | 94.0% |
| 3673291 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.51 | 25.0 | 2.94e-01 | 95.5% | 65.6% |