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IMGVR_UViG_3300021467_000205-3300021467-Ga0190334_100023536
Arc-VirIMGVR_UViG_3300021467_000205-3300021467-Ga0190334_100023536
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-64
Domain cluster:
rep: AB916497.1__BAS32804.1__X__00006__D2-48
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07037.18 best | YfeC-like | 30.8 | 4.40e-07 | 85.2% | 32.0% |
D2
high
residues 102-180
Domain cluster:
representative
CATH (55)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.79 | 60.0 | 6.12e-01 | 100.0% | 82.1% |
| 1i36A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.74 | 56.0 | 5.19e-01 | 94.9% | 63.6% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.73 | 46.0 | 3.42e-01 | 100.0% | 27.2% |
| 5z4zC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.73 | 43.0 | 4.15e-01 | 87.3% | 52.3% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.68 | 54.0 | 4.40e-01 | 84.8% | 53.5% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 45.0 | 3.42e-01 | 89.9% | 30.7% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 44.0 | 4.29e-01 | 100.0% | 63.2% |
| 3dkqA02 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.65 | 37.0 | 4.72e-01 | 96.2% | 95.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.64 | 50.0 | 4.47e-01 | 83.5% | 66.4% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.63 | 47.0 | 4.34e-01 | 78.5% | 84.0% |
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 40.0 | 4.57e-01 | 100.0% | 86.7% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 40.0 | 3.86e-01 | 72.2% | 58.6% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.62 | 43.0 | 3.84e-01 | 72.2% | 51.3% |
| 1f44A01 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.62 | 50.0 | 3.76e-01 | 87.3% | 58.2% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 52.0 | 4.17e-01 | 89.9% | 50.3% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 37.0 | 3.46e-01 | 84.8% | 49.0% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.62 | 41.0 | 4.02e-01 | 100.0% | 62.4% |
| 2pjqA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.62 | 40.0 | 3.84e-01 | 72.2% | 57.3% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 47.0 | 4.25e-01 | 83.5% | 87.4% |
| 3k59A07 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.61 | 46.0 | 3.83e-01 | 81.0% | 88.0% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 49.0 | 4.00e-01 | 88.6% | 51.7% |
| 5k7fA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 49.0 | 4.08e-01 | 88.6% | 52.2% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 42.0 | 3.76e-01 | 82.3% | 53.7% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 48.0 | 3.89e-01 | 100.0% | 47.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 44.0 | 4.03e-01 | 82.3% | 86.2% |
| 4me9B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 46.0 | 3.54e-01 | 87.3% | 39.8% |
| 2lmgA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 36.0 | 3.76e-01 | 70.9% | 67.6% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.57 | 41.0 | 3.79e-01 | 75.9% | 57.1% |
| 7k18A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.57 | 47.0 | 3.88e-01 | 100.0% | 51.5% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 51.0 | 3.79e-01 | 98.7% | 61.2% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 3.45e-01 | 89.9% | 34.5% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.56 | 44.0 | 3.52e-01 | 83.5% | 51.6% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.56 | 43.0 | 3.92e-01 | 83.5% | 87.2% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 45.0 | 3.83e-01 | 87.3% | 57.6% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 49.0 | 3.88e-01 | 100.0% | 92.7% |
| 2b3yA01 | 3.30.499.10 | Alpha Beta › 2-Layer Sandwich › Aconitase; domain 3 › Aconitase, domain 3 | 0.54 | 46.0 | 3.41e-01 | 100.0% | 78.2% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 49.0 | 4.16e-01 | 100.0% | 96.1% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.54 | 47.0 | 3.75e-01 | 100.0% | 74.1% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 42.0 | 3.77e-01 | 84.8% | 71.6% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.53 | 42.0 | 4.00e-01 | 91.1% | 73.0% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 38.0 | 3.82e-01 | 100.0% | 72.3% |
| 2xppA00 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.52 | 46.0 | 3.76e-01 | 93.7% | 73.7% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 43.0 | 3.41e-01 | 91.1% | 45.5% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.51 | 43.0 | 3.57e-01 | 93.7% | 72.9% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 44.0 | 4.04e-01 | 93.7% | 80.6% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 45.0 | 3.75e-01 | 100.0% | 80.4% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 38.0 | 3.61e-01 | 92.4% | 67.0% |
| 6wv5A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.51 | 43.0 | 3.56e-01 | 100.0% | 52.9% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 45.0 | 3.82e-01 | 94.9% | 61.0% |
| 6opmD01 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.50 | 46.0 | 3.21e-01 | 98.7% | 42.9% |
| 3q18A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 43.0 | 3.81e-01 | 94.9% | 83.6% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 44.0 | 3.74e-01 | 96.2% | 70.0% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.50 | 40.0 | 3.60e-01 | 87.3% | 64.0% |
| 1gaxA02 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.50 | 43.0 | 3.10e-01 | 94.9% | 48.0% |
| 3hgtA00 | 3.40.50.12360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 43.0 | 3.02e-01 | 100.0% | 78.7% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5061725 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.74 | 43.0 | 4.32e-01 | 86.1% | 57.5% |
| 5049361 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.72 | 46.0 | 4.64e-01 | 100.0% | 65.0% |
| 3784813 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.71 | 57.0 | 5.30e-01 | 86.1% | 81.6% |
| 3607406 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.70 | 44.0 | 4.45e-01 | 70.9% | 63.7% |
| 3781725 | 3291.1.1.12 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF1689 | 0.69 | 62.0 | 5.30e-01 | 100.0% | 80.0% |
| 4972595 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.69 | 57.0 | 5.28e-01 | 93.7% | 99.0% |
| 3718013 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.68 | 53.0 | 4.99e-01 | 83.5% | 84.2% |
| 3390311 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.67 | 43.0 | 3.87e-01 | 98.7% | 47.3% |
| 3705223 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.67 | 53.0 | 3.37e-01 | 84.8% | 19.5% |
| 4955750 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.67 | 40.0 | 4.11e-01 | 70.9% | 62.7% |
| 3903368 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.66 | 53.0 | 4.35e-01 | 88.6% | 94.0% |
| 3587542 | 605.1.1.241 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF1430 | 0.65 | 51.0 | 4.74e-01 | 84.8% | 90.0% |
| 4518916 | 4144.1.1.8 ↗ | alpha duplicates or obligate multimers › YejL-like › YejL-like › YejL-like › GlutR_dimer | 0.65 | 44.0 | 4.57e-01 | 70.9% | 100.0% |
| 4067677 | 3826.1.1.25 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › GlutR_dimer | 0.64 | 44.0 | 4.51e-01 | 72.2% | 96.2% |
| 4028151 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.64 | 41.0 | 3.89e-01 | 100.0% | 54.7% |
| 4944123 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.63 | 55.0 | 4.71e-01 | 97.5% | 87.7% |
| 5036080 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.63 | 55.0 | 4.49e-01 | 96.2% | 75.9% |
| 3280449 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.63 | 54.0 | 3.70e-01 | 100.0% | 72.8% |
| 5033486 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.62 | 54.0 | 4.48e-01 | 96.2% | 78.6% |
| 4999943 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.62 | 54.0 | 4.66e-01 | 97.5% | 89.6% |
| 4937180 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.62 | 52.0 | 4.41e-01 | 92.4% | 63.8% |
| 4975933 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.62 | 48.0 | 4.38e-01 | 83.5% | 79.0% |
| 5028871 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.62 | 54.0 | 4.50e-01 | 96.2% | 81.5% |
| 3290353 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.61 | 53.0 | 3.60e-01 | 100.0% | 61.3% |
| 5037929 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.60 | 51.0 | 4.50e-01 | 94.9% | 87.5% |
| 4942810 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.59 | 50.0 | 4.19e-01 | 94.9% | 77.9% |
| 5056690 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.59 | 52.0 | 4.50e-01 | 98.7% | 87.2% |
| 5014971 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.58 | 51.0 | 3.81e-01 | 100.0% | 67.0% |
| 5029480 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.58 | 51.0 | 3.82e-01 | 100.0% | 67.3% |
| 4938242 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.58 | 51.0 | 4.35e-01 | 98.7% | 82.3% |
| 3602900 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.58 | 49.0 | 4.22e-01 | 96.2% | 85.4% |
| 4987618 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.57 | 43.0 | 3.81e-01 | 100.0% | 54.8% |
| 5004570 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.57 | 45.0 | 4.67e-01 | 83.5% | 92.0% |
| 5012961 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.57 | 49.0 | 4.18e-01 | 96.2% | 85.4% |
| 4491518 | 7516.1.1.153 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_transf_8 | 0.57 | 41.0 | 2.42e-01 | 96.2% | 10.5% |
| 5029518 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.57 | 48.0 | 4.10e-01 | 96.2% | 87.4% |
| 3936693 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 42.0 | 3.90e-01 | 81.0% | 63.0% |
| 4996069 | 604.10.1.0 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac | 0.55 | 45.0 | 4.35e-01 | 94.9% | 77.8% |
| 4996688 | 601.37.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Photosystem II lipoprotein Psb27 › Photosystem II lipoprotein Psb27 | 0.55 | 46.0 | 4.27e-01 | 93.7% | 100.0% |
| 5036461 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.54 | 41.0 | 3.95e-01 | 100.0% | 70.0% |
| 4013499 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.54 | 46.0 | 3.77e-01 | 98.7% | 88.7% |
| 4038749 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 48.0 | 4.25e-01 | 98.7% | 96.5% |
| 3732719 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.54 | 49.0 | 4.06e-01 | 100.0% | 87.4% |
| 5083938 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.53 | 45.0 | 3.52e-01 | 100.0% | 72.6% |
| 3582234 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 42.0 | 3.87e-01 | 93.7% | 67.0% |
| 4926826 | 4033.1.1.1 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N | 0.53 | 43.0 | 3.70e-01 | 89.9% | 67.2% |
| 4032384 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.52 | 41.0 | 4.16e-01 | 84.8% | 85.0% |
| 4132205 | 4033.1.1.1 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N | 0.52 | 41.0 | 3.74e-01 | 87.3% | 65.5% |
| 4538265 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 45.0 | 3.40e-01 | 100.0% | 71.9% |
| 3959851 | 109.47.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical C-terminal domain in magnesium chelatase catalytic subunit › Helical C-terminal domain in magnesium chelatase catalytic subunit | 0.52 | 38.0 | 3.34e-01 | 81.0% | 52.2% |
| 4955947 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.52 | 36.0 | 3.75e-01 | 75.9% | 82.7% |
| 5065815 | 601.35.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Nucleotidyl transferase L544 helical domain › Nucleotidyl transferase L544 helical domain | 0.51 | 45.0 | 3.86e-01 | 98.7% | 81.6% |
| 3930556 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.51 | 44.0 | 3.91e-01 | 96.2% | 100.0% |
| 3616104 | 632.13.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like | 0.50 | 36.0 | 3.83e-01 | 84.8% | 93.8% |
| 4236831 | 604.6.1.50 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 | 0.50 | 42.0 | 4.26e-01 | 91.1% | 90.0% |
D3
high
residues 195-267
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fcyB02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.82 | 64.0 | 6.72e-01 | 91.8% | 93.8% |
| 2qbyA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.74 | 59.0 | 5.49e-01 | 86.3% | 86.7% |
| 3lulA01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.67 | 56.0 | 4.84e-01 | 90.4% | 99.1% |
| 4ixjA01 | 3.30.1300.80 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.67 | 46.0 | 4.55e-01 | 71.2% | 70.1% |
| 1a3gA01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.67 | 55.0 | 4.45e-01 | 89.0% | 86.7% |
| 3solA00 | 1.20.58.1630 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS | 0.67 | 54.0 | 5.06e-01 | 90.4% | 83.5% |
| 1n5uA05 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.58 | 42.0 | 3.65e-01 | 75.3% | 52.7% |
| 1rktA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 42.0 | 3.34e-01 | 76.7% | 60.3% |
| 3bgeA01 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.58 | 43.0 | 4.03e-01 | 100.0% | 62.5% |
| 1vpdA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.54 | 41.0 | 3.52e-01 | 86.3% | 85.5% |
| 3g0oA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.54 | 40.0 | 3.40e-01 | 79.5% | 85.1% |
| 1szhA02 | 1.10.150.370 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Caenorhabditis elegans Her-1, C-terminal domain | 0.52 | 36.0 | 3.57e-01 | 75.3% | 75.6% |
| 1nrwA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.52 | 42.0 | 3.35e-01 | 84.9% | 66.2% |
| 3fghA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.51 | 35.0 | 3.66e-01 | 75.3% | 79.1% |
| 1n5uA01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.51 | 43.0 | 3.74e-01 | 89.0% | 87.4% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3164500 | 101.1.1.47 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Mu_2 | 0.81 | 62.0 | 6.38e-01 | 86.3% | 84.3% |
| 3942599 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.81 | 63.0 | 6.13e-01 | 87.7% | 76.2% |
| 2479 | 101.1.1.47 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Mu_2 | 0.78 | 61.0 | 6.14e-01 | 91.8% | 84.0% |
| 4362265 | 101.28.1.1 ↗ | alpha arrays › HTH › helical bundles in FlhC-like proteins › helical bundles in FlhC-like proteins › FlhC | 0.78 | 58.0 | 5.14e-01 | 79.5% | 61.9% |
| 5042704 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.75 | 58.0 | 6.06e-01 | 86.3% | 93.8% |
| 4961270 | 101.1.2.101 ↗ | alpha arrays › HTH › HTH › winged helix domain › Cdc6_C | 0.72 | 57.0 | 5.08e-01 | 86.3% | 80.0% |
| 3392763 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.72 | 59.0 | 5.64e-01 | 90.4% | 90.6% |
| 4392375 | 101.1.2.101 ↗ | alpha arrays › HTH › HTH › winged helix domain › Cdc6_C | 0.71 | 59.0 | 5.13e-01 | 90.4% | 74.5% |
| 3372352 | 101.1.1.69 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_7 | 0.70 | 50.0 | 5.07e-01 | 89.0% | 78.6% |
| 3549847 | 101.1.2.394 ↗ | alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1 | 0.69 | 58.0 | 3.68e-01 | 93.2% | 22.1% |
| 1031092 | 3705.1.1.1 ↗ | alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › T2SS_PulS_OutS | 0.68 | 55.0 | 5.10e-01 | 90.4% | 78.9% |
| 4022876 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 51.0 | 4.96e-01 | 86.3% | 87.5% |
| 3991429 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 53.0 | 4.73e-01 | 98.6% | 62.9% |
| 5051738 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 50.0 | 5.13e-01 | 89.0% | 88.6% |
| 3684722 | 101.1.2.22 ↗ | alpha arrays › HTH › HTH › winged helix domain › PCI | 0.59 | 49.0 | 4.46e-01 | 93.2% | 95.0% |
| 3389110 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.57 | 42.0 | 3.67e-01 | 79.5% | 53.9% |
| 3486403 | 10.12.1.0 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix | 0.56 | 39.0 | 2.48e-01 | 87.7% | 14.5% |
| 3378059 | 10.12.1.10 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC,JmjN | 0.55 | 38.0 | 2.45e-01 | 87.7% | 14.3% |
| 3989810 | 3291.1.1.5 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Relaxase_C | 0.53 | 37.0 | 3.42e-01 | 72.6% | 63.2% |
D4
high
residues 275-469
Domain cluster:
rep: AB916497.1__BAS32805.1__X__00007__D17-171
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02914.22 best | DDE_2 | 25.7 | 1.30e-05 | 94.4% | 75.1% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8b4hA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.85 | 66.0 | 7.24e-01 | 95.4% | 95.7% |
| 1bcoA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.72 | 68.0 | 6.49e-01 | 99.5% | 86.9% |
| 1yqzA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.65 | 25.0 | 3.31e-01 | 95.4% | 62.0% |
| 3cgbA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.65 | 25.0 | 3.27e-01 | 95.9% | 61.8% |
| 7pikC01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.63 | 57.0 | 5.61e-01 | 95.4% | 88.9% |
| 3uxjA01 | 3.30.1130.10 | Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain | 0.61 | 29.0 | 3.68e-01 | 96.9% | 72.9% |
| 7essA01 | 3.30.420.140 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain | 0.59 | 35.0 | 4.20e-01 | 90.3% | 86.4% |
| 4o8uA00 | 3.30.420.440 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF4152 | 0.59 | 47.0 | 4.52e-01 | 84.1% | 100.0% |
| 3gocA00 | 3.30.2170.10 | Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily | 0.59 | 42.0 | 3.99e-01 | 72.3% | 84.2% |
| 2g2sA00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.57 | 19.0 | 3.29e-01 | 93.8% | 90.6% |
| 1vhxB00 | 3.30.420.140 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain | 0.57 | 35.0 | 4.13e-01 | 74.4% | 87.0% |
| 2ymbA00 | 3.30.870.30 | Alpha Beta › 2-Layer Sandwich › Endonuclease; Chain A › MITD, C-terminal phospholipase D-like domain | 0.51 | 34.0 | 3.77e-01 | 97.9% | 83.7% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5006208 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.89 | 64.0 | 7.00e-01 | 100.0% | 86.7% |
| 3588051 | 2484.1.1.202 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_2 | 0.88 | 66.0 | 6.92e-01 | 100.0% | 82.8% |
| 5084008 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.88 | 68.0 | 7.07e-01 | 100.0% | 85.0% |
| 3955433 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.88 | 70.0 | 7.37e-01 | 100.0% | 88.9% |
| 3985938 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.88 | 67.0 | 6.74e-01 | 100.0% | 77.9% |
| 4957414 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.87 | 67.0 | 6.93e-01 | 100.0% | 82.7% |
| 3971375 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.87 | 67.0 | 6.82e-01 | 100.0% | 80.9% |
| 3969957 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.87 | 66.0 | 6.70e-01 | 100.0% | 78.9% |
| 4008012 | 2484.1.1.202 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_2 | 0.86 | 66.0 | 6.82e-01 | 100.0% | 82.2% |
| 3982837 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.86 | 66.0 | 7.20e-01 | 100.0% | 92.1% |
| 3985723 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.86 | 66.0 | 6.51e-01 | 100.0% | 74.1% |
| 3986284 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.86 | 65.0 | 6.56e-01 | 100.0% | 76.9% |
| 4259031 | 2484.1.1.219 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF29688 | 0.86 | 75.0 | 7.72e-01 | 100.0% | 94.1% |
| 3283910 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.86 | 62.0 | 6.96e-01 | 95.9% | 92.3% |
| 4944586 | 2484.1.1.117 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve_3 | 0.86 | 66.0 | 6.93e-01 | 100.0% | 85.6% |
| 3588441 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.86 | 66.0 | 7.15e-01 | 100.0% | 92.7% |
| 5068137 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.85 | 63.0 | 6.24e-01 | 100.0% | 73.0% |
| 3962721 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.85 | 51.0 | 6.63e-01 | 84.1% | 100.0% |
| 5064316 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.85 | 64.0 | 6.84e-01 | 100.0% | 87.6% |
| 4926839 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.85 | 64.0 | 6.98e-01 | 97.9% | 90.9% |
| 3519322 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.85 | 65.0 | 6.58e-01 | 100.0% | 79.0% |
| 4312891 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.84 | 69.0 | 7.08e-01 | 100.0% | 88.1% |
| 4494081 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.84 | 69.0 | 6.88e-01 | 100.0% | 82.0% |
| 4351609 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.84 | 69.0 | 7.02e-01 | 100.0% | 86.3% |
| 4099374 | 2484.1.1.202 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_2 | 0.84 | 64.0 | 6.79e-01 | 100.0% | 87.4% |
| 4929599 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.83 | 63.0 | 5.79e-01 | 97.9% | 62.5% |
| 4933551 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.83 | 58.0 | 6.66e-01 | 97.9% | 93.9% |
| 4567161 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.83 | 68.0 | 7.01e-01 | 100.0% | 89.2% |
| 5052211 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.83 | 62.0 | 7.10e-01 | 93.3% | 100.0% |
| 3952641 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.82 | 64.0 | 6.40e-01 | 100.0% | 79.0% |
| 4141576 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.82 | 68.0 | 7.06e-01 | 100.0% | 90.3% |
| 3942598 | 2484.1.1.219 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF29688 | 0.81 | 78.0 | 7.26e-01 | 100.0% | 83.9% |
| 5027917 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.81 | 61.0 | 5.60e-01 | 97.9% | 62.1% |
| 4927805 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.81 | 59.0 | 6.55e-01 | 97.4% | 91.3% |
| 3961927 | 2484.1.1.194 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_3 | 0.80 | 61.0 | 6.67e-01 | 96.9% | 93.8% |
| 4929499 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.80 | 56.0 | 6.22e-01 | 96.4% | 86.9% |
| 4943224 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.80 | 59.0 | 6.29e-01 | 97.9% | 85.9% |
| 3249604 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.80 | 63.0 | 6.01e-01 | 100.0% | 71.4% |
| 4928281 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.80 | 59.0 | 5.53e-01 | 97.9% | 63.0% |
| 3988130 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.80 | 51.0 | 6.38e-01 | 83.1% | 100.0% |
| 4944877 | 2484.1.1.117 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve_3 | 0.80 | 58.0 | 6.34e-01 | 97.9% | 88.5% |
| 3588285 | 2484.1.1.202 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve, rve_2 | 0.79 | 64.0 | 6.35e-01 | 100.0% | 80.5% |
| 5030453 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.79 | 58.0 | 5.43e-01 | 97.9% | 62.1% |
| 3274129 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.79 | 62.0 | 6.09e-01 | 100.0% | 74.8% |
| 2887749 | 2484.1.1.219 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF29688 | 0.78 | 75.0 | 7.00e-01 | 100.0% | 86.0% |
| 5027953 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.78 | 59.0 | 6.11e-01 | 97.9% | 81.6% |
| 5028784 | 2484.1.1.117 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve_3 | 0.78 | 61.0 | 5.62e-01 | 97.9% | 65.4% |
| 4632712 | 2484.1.1.219 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF29688 | 0.77 | 71.0 | 6.95e-01 | 100.0% | 90.2% |
| 4952725 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.77 | 50.0 | 5.95e-01 | 97.9% | 94.8% |
| 3788859 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.76 | 54.0 | 5.55e-01 | 95.9% | 75.1% |
| 3914424 | 2484.1.1.242 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rva_4 | 0.74 | 63.0 | 5.91e-01 | 100.0% | 73.9% |
| 4927589 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.74 | 63.0 | 6.40e-01 | 97.9% | 89.5% |
| 5029192 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.74 | 58.0 | 6.08e-01 | 94.9% | 87.8% |
| 3505730 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.72 | 59.0 | 6.07e-01 | 100.0% | 87.9% |
| 11137 | 2484.1.1.33 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_2 | 0.72 | 68.0 | 6.58e-01 | 99.5% | 89.8% |
| 4968579 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.68 | 55.0 | 4.87e-01 | 97.9% | 60.7% |
| 3504726 | 2484.1.1.268 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF5641 | 0.67 | 64.0 | 5.75e-01 | 100.0% | 88.6% |
| 5008722 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 56.0 | 4.77e-01 | 97.9% | 58.4% |
| 5005291 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.64 | 58.0 | 5.53e-01 | 97.9% | 83.2% |
| 5052885 | 2484.1.1.101 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 | 0.64 | 58.0 | 5.46e-01 | 94.4% | 97.4% |
| 3962011 | 2484.1.1.9 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve | 0.63 | 45.0 | 5.21e-01 | 94.9% | 100.0% |
| 4977119 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.63 | 59.0 | 5.61e-01 | 98.5% | 86.7% |
| 5040335 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.63 | 56.0 | 5.58e-01 | 96.4% | 88.8% |
| 4009433 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.63 | 59.0 | 4.63e-01 | 97.4% | 68.4% |
| 4958703 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.63 | 58.0 | 4.86e-01 | 97.9% | 71.6% |
| 4958777 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.63 | 58.0 | 4.84e-01 | 97.9% | 71.9% |
| 5060820 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.63 | 58.0 | 4.32e-01 | 98.5% | 65.2% |
| 5027997 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.61 | 57.0 | 5.12e-01 | 97.9% | 73.7% |
| 4212008 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.61 | 57.0 | 4.67e-01 | 98.5% | 67.0% |
| 4940124 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.61 | 56.0 | 4.79e-01 | 97.9% | 63.0% |
| 5050956 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.61 | 56.0 | 4.68e-01 | 97.9% | 71.9% |
| 4451157 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.60 | 56.0 | 5.25e-01 | 99.5% | 82.6% |
| 4122250 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 55.0 | 4.81e-01 | 97.9% | 80.7% |
| 4952348 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 53.0 | 5.39e-01 | 97.4% | 96.9% |
| 4970782 | 2484.7.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Uncharacterized protein PF2046 › Uncharacterized protein PF2046 › DUF4152 | 0.57 | 46.0 | 4.42e-01 | 84.1% | 100.0% |
| 5053361 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.55 | 50.0 | 4.47e-01 | 95.9% | 92.1% |
| 5026711 | 2484.7.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Uncharacterized protein PF2046 › Uncharacterized protein PF2046 › DUF4152 | 0.53 | 47.0 | 4.46e-01 | 93.8% | 89.8% |
| 5041805 | 2484.7.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Uncharacterized protein PF2046 › Uncharacterized protein PF2046 › DUF4152 | 0.52 | 44.0 | 4.43e-01 | 94.4% | 88.2% |
D5
high
residues 675-740
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r4gA02 | 1.10.10.1970 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › TERT catalytic subunit-like | 0.65 | 51.0 | 5.16e-01 | 100.0% | 90.6% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.63 | 55.0 | 5.02e-01 | 98.5% | 86.4% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.62 | 42.0 | 3.95e-01 | 71.2% | 59.8% |
| 1sz9C00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 49.0 | 3.91e-01 | 92.4% | 47.9% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.60 | 43.0 | 3.50e-01 | 75.8% | 52.1% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.30e-01 | 98.5% | 88.4% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.59 | 46.0 | 4.28e-01 | 87.9% | 86.0% |
| 1juqC00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 48.0 | 3.80e-01 | 97.0% | 66.4% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.57 | 49.0 | 3.55e-01 | 100.0% | 73.3% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.57 | 43.0 | 3.47e-01 | 81.8% | 84.0% |
| 2oyoA02 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.55 | 44.0 | 3.64e-01 | 89.4% | 86.4% |
| 1zq3P00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.55 | 38.0 | 3.85e-01 | 93.9% | 72.1% |
| 3ay8A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 46.0 | 3.71e-01 | 98.5% | 86.0% |
| 2imiB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 44.0 | 3.59e-01 | 98.5% | 84.3% |
| 2e8gA01 | 1.20.1440.150 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.53 | 45.0 | 3.78e-01 | 100.0% | 75.0% |
| 1x2nA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.53 | 40.0 | 4.20e-01 | 93.9% | 90.0% |
| 6tmfT00 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.51 | 39.0 | 4.02e-01 | 86.4% | 87.5% |
| 1dp4A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.50 | 43.0 | 3.07e-01 | 98.5% | 76.3% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4585871 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 51.0 | 4.15e-01 | 100.0% | 41.6% |
| 4026983 | 604.1.1.135 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF155 | 0.58 | 48.0 | 3.49e-01 | 100.0% | 80.9% |
| 5032496 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.56 | 43.0 | 3.54e-01 | 86.4% | 80.0% |
| 3707358 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.55 | 45.0 | 3.16e-01 | 92.4% | 50.7% |
| 5003564 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.55 | 45.0 | 3.38e-01 | 97.0% | 70.5% |