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IMGVR_UViG_3300021488_000009-3300021488-Ga0190305_10001769

Arc-Vir

IMGVR_UViG_3300021488_000009-3300021488-Ga0190305_10001769

Quality

79.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-60
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.68 59.0 3.62e-01 100.0% 32.6%
4gdxB00 3.60.20.40 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit 0.66 48.0 3.41e-01 80.7% 58.2%
1e3hA03 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.66 47.0 3.17e-01 75.4% 64.3%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.64 45.0 3.92e-01 80.7% 45.4%
7c2fB01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.62 45.0 3.93e-01 77.2% 84.9%
3g9kF01 3.60.20.40 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit 0.62 46.0 3.40e-01 82.5% 50.9%
1vypX00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.61 50.0 3.14e-01 96.5% 58.8%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.61 46.0 3.41e-01 84.2% 90.7%
4mfzA02 3.40.630.120 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.60 50.0 3.84e-01 100.0% 95.9%
2kgfA00 1.10.375.10 Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein 0.60 45.0 3.38e-01 80.7% 35.0%
6aieA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 51.0 3.65e-01 100.0% 72.0%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.59 49.0 4.66e-01 100.0% 78.9%
1apyB00 3.60.20.30 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › (Glycosyl)asparaginase 0.58 44.0 3.37e-01 84.2% 51.1%
3uoxB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 48.0 3.07e-01 93.0% 43.4%
2c60A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.58 35.0 3.18e-01 98.2% 43.0%
1yx1A00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.57 48.0 3.22e-01 98.2% 59.2%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 50.0 3.62e-01 100.0% 83.3%
1xjvA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 45.0 3.42e-01 89.5% 85.2%
3weeA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 49.0 3.47e-01 100.0% 60.7%
3zwbA01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.55 46.0 3.03e-01 98.2% 41.9%
2wr7C01 3.90.20.10 Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › 0.55 46.0 3.09e-01 98.2% 46.7%
2kinA00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.55 45.0 3.09e-01 100.0% 42.0%
2jkgA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.55 39.0 2.92e-01 78.9% 88.5%
2kyyA00 3.30.950.30 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Schlafen, AAA domain 0.54 45.0 3.46e-01 100.0% 50.3%
3ihlB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 47.0 3.18e-01 100.0% 27.9%
2pw4A00 1.10.3300.10 Mainly Alpha › Orthogonal Bundle › Jann2411-like fold › Jann2411-like domain 0.54 46.0 3.25e-01 96.5% 84.7%
5xbfA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 33.0 2.94e-01 77.2% 37.9%
4hstA01 1.10.439.10 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 0.54 46.0 3.48e-01 100.0% 86.8%
2ap1A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 46.0 3.56e-01 100.0% 64.7%
2o3iA01 3.40.1610.10 Alpha Beta › 3-Layer(aba) Sandwich › CV3147-like fold › CV3147-like domain 0.54 45.0 2.96e-01 91.2% 31.4%
3foeA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.54 36.0 3.48e-01 91.2% 59.4%
5c9iD01 1.10.439.10 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 0.53 40.0 3.03e-01 87.7% 77.0%
2gupA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 45.0 3.86e-01 100.0% 85.6%
7ct1A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 34.0 3.07e-01 96.5% 43.5%
7plsA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 37.0 3.29e-01 100.0% 49.5%
1wdkC01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.52 43.0 3.03e-01 100.0% 32.4%
4hizA04 4.10.1090.10 Few Secondary Structures › Irregular › Endosialidase, domain 4 › Endosialidase, domain 4 0.50 36.0 2.78e-01 100.0% 29.3%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3958367 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.71 50.0 5.11e-01 96.5% 76.4%
5050929 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.70 40.0 3.63e-01 84.2% 42.7%
5026943 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 52.0 3.84e-01 100.0% 30.3%
3444901 4954.1.1.0 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit 0.67 52.0 3.75e-01 100.0% 28.6%
1888906 2002.1.1.39 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_3 0.66 50.0 3.04e-01 84.2% 43.8%
5004463 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 52.0 3.29e-01 89.5% 56.2%
3800293 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 51.0 4.50e-01 100.0% 60.2%
3839854 2498.1.1.17 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like 0.62 43.0 3.03e-01 89.5% 21.5%
4949578 3957.1.1.0 a+b two layers › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 0.61 51.0 5.10e-01 96.5% 93.3%
3719707 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 52.0 3.44e-01 96.5% 36.3%
4034385 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.61 44.0 3.57e-01 80.7% 39.1%
3306435 245.3.1.1 a+b two layers › Ribonuclease PH domain 2-like › Colicin S4 receptor-binding domain › Colicin S4 receptor-binding domain › BRX 0.61 44.0 4.56e-01 84.2% 85.2%
4461056 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.60 41.0 3.68e-01 77.2% 48.2%
3335794 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 47.0 3.17e-01 89.5% 55.7%
3743565 109.4.1.313 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP20_N 0.59 49.0 3.15e-01 98.2% 45.0%
1176726 4325.1.1.2 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › P53_C 0.58 48.0 4.57e-01 100.0% 78.9%
3717426 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.58 51.0 3.10e-01 100.0% 49.0%
223785 4963.1.1.1 alpha complex topology › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_4 0.58 46.0 2.88e-01 89.5% 29.9%
4928783 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 39.0 3.84e-01 75.4% 65.1%
3254341 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.57 41.0 2.70e-01 75.4% 17.0%
3603146 2008.1.1.95 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnII 0.57 47.0 3.14e-01 100.0% 44.2%
4191800 3075.1.1.0 a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA 0.57 39.0 4.01e-01 71.9% 89.1%
3439386 2004.1.1.26 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin 0.57 47.0 3.00e-01 100.0% 40.6%
3281747 213.5.1.1 a+b three layers › Nat/Ivy › AlkZ C-terminal domain › AlkZ C-terminal domain › AlkZ-like 0.57 46.0 3.80e-01 89.5% 86.7%
5073213 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.56 50.0 3.38e-01 100.0% 88.6%
3600035 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 32.0 3.10e-01 70.2% 46.2%
3454374 207.1.1.96 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_At1g61320_AtMIF1 0.56 45.0 2.79e-01 91.2% 36.5%
3782687 2003.1.5.63 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CARME 0.56 40.0 2.48e-01 78.9% 22.1%
3741882 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.56 46.0 2.95e-01 100.0% 29.4%
3620852 3075.1.1.0 a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA 0.56 38.0 3.90e-01 71.9% 92.7%
3177693 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.55 43.0 2.64e-01 84.2% 56.6%
3599377 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.55 44.0 2.81e-01 100.0% 27.4%
3574531 193.1.1.1 alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › CH 0.54 45.0 3.28e-01 91.2% 57.5%
3987094 4967.1.1.11 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › GIIM 0.54 45.0 3.68e-01 100.0% 75.0%
3698801 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.54 44.0 2.77e-01 98.2% 27.6%
4958814 3457.1.1.3 alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Arc_PepC_II 0.54 39.0 2.58e-01 78.9% 90.0%
3684154 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.54 44.0 4.00e-01 93.0% 100.0%
1833712 206.1.3.27 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › CP_ATPgrasp_2 0.54 44.0 3.06e-01 93.0% 85.8%
3853833 304.9.1.81 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.54 38.0 2.73e-01 75.4% 50.9%
4027383 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.53 43.0 2.75e-01 100.0% 30.5%
3815071 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.53 42.0 2.52e-01 96.5% 18.8%
3807532 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 45.0 2.65e-01 96.5% 31.5%
4991377 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.52 43.0 2.94e-01 100.0% 58.4%
3317848 2004.1.1.250 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.52 44.0 2.81e-01 98.2% 29.6%
4944096 304.51.1.1 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Cas6_C 0.52 42.0 3.35e-01 93.0% 52.4%
3305417 4232.1.1.0 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 0.52 34.0 3.53e-01 70.2% 87.3%
3981752 829.1.1.1 a+b duplicates or obligate multimers › NinB › NinB › NinB › NinB 0.51 43.0 3.25e-01 91.2% 63.8%
3326491 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 41.0 3.00e-01 98.2% 32.8%
3376457 2484.1.1.110 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MULE 0.51 43.0 3.69e-01 100.0% 71.0%
3213645 267.1.1.0 a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.51 43.0 2.88e-01 98.2% 91.2%
4325826 225.1.1.27 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › PF26329 0.51 44.0 2.86e-01 98.2% 28.6%
3373091 221.1.1.2 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.50 35.0 3.69e-01 98.2% 84.0%