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IMGVR_UViG_3300021493_000061-3300021493-Ga0190306_10019482
Arc-VirIMGVR_UViG_3300021493_000061-3300021493-Ga0190306_10019482
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-60
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lmmC04 | 1.10.10.2340 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.56 | 37.0 | 3.27e-01 | 80.0% | 47.1% |
| 2c43A01 | 3.90.470.20 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain | 0.55 | 47.0 | 3.54e-01 | 93.3% | 49.0% |
| 1fokA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 39.0 | 3.48e-01 | 78.3% | 94.3% |
| 5dx9A01 | 3.30.70.1020 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trehalose-6-phosphate phosphatase related protein; domain 2 | 0.53 | 41.0 | 3.90e-01 | 85.0% | 86.1% |
| 1xmxA03 | 1.10.10.680 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Hypothetical protein VC1899 (Restriction endonuclease-like) | 0.52 | 42.0 | 3.72e-01 | 90.0% | 69.7% |
| 4bxiA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.52 | 45.0 | 3.39e-01 | 96.7% | 61.0% |
| 1z52A02 | 3.30.412.10 | Alpha Beta › 2-Layer Sandwich › Proaerolysin; Chain A, domain 2 › Proaerolysin, chain A, domain 2 | 0.51 | 43.0 | 3.21e-01 | 100.0% | 60.1% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3728487 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 49.0 | 3.40e-01 | 76.7% | 76.8% |
| 3296784 | 304.6.1.5 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › Cytokin-bind | 0.67 | 48.0 | 3.05e-01 | 96.7% | 15.9% |
| 4143442 | 3008.1.1.0 ↗ | a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.59 | 48.0 | 4.32e-01 | 96.7% | 100.0% |
| 3212567 | 2.1.1.92 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_D_N | 0.58 | 46.0 | 3.65e-01 | 95.0% | 95.2% |
| 3610633 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.58 | 49.0 | 3.27e-01 | 91.7% | 43.6% |
| 3718510 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.54 | 49.0 | 2.79e-01 | 100.0% | 16.3% |
| 3367272 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.54 | 46.0 | 3.15e-01 | 100.0% | 71.7% |
| 3199266 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.52 | 42.0 | 2.48e-01 | 88.3% | 12.3% |
| 3742471 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 45.0 | 4.28e-01 | 98.3% | 92.9% |
D2
medium
residues 61-155
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF24608.3 best | PDDEXK_15 | 30.7 | 4.10e-07 | 89.5% | 36.6% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1i74A02 | 3.10.310.20 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain | 0.64 | 57.0 | 5.30e-01 | 100.0% | 86.6% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.61 | 38.0 | 3.89e-01 | 81.1% | 64.8% |
| 4i93A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.61 | 42.0 | 4.22e-01 | 70.5% | 96.8% |
| 4py9A02 | 3.10.310.30 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › | 0.60 | 53.0 | 4.85e-01 | 100.0% | 81.7% |
| 3ieyB00 | 3.40.1350.150 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.59 | 37.0 | 3.18e-01 | 81.1% | 39.5% |
| 2vsqA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.58 | 44.0 | 3.41e-01 | 82.1% | 72.6% |
| 5ghrA02 | 3.10.310.30 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › | 0.57 | 51.0 | 4.68e-01 | 100.0% | 80.8% |
| 3lulA02 | 3.20.10.10 | Alpha Beta › Alpha-Beta Barrel › D-amino Acid Aminotransferase; Chain A, domain 2 › D-amino Acid Aminotransferase, subunit A, domain 2 | 0.57 | 49.0 | 4.24e-01 | 97.9% | 81.3% |
| 3qqmA02 | 3.20.10.10 | Alpha Beta › Alpha-Beta Barrel › D-amino Acid Aminotransferase; Chain A, domain 2 › D-amino Acid Aminotransferase, subunit A, domain 2 | 0.56 | 48.0 | 4.38e-01 | 97.9% | 91.7% |
| 2qwvA00 | 3.40.1280.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain | 0.56 | 49.0 | 3.97e-01 | 98.9% | 66.0% |
| 3fovA00 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.55 | 38.0 | 3.75e-01 | 81.1% | 66.7% |
| 1dgmA01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 48.0 | 3.45e-01 | 96.8% | 60.1% |
| 6r77A02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.54 | 45.0 | 3.84e-01 | 94.7% | 98.8% |
| 3fcsB03 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.53 | 48.0 | 3.52e-01 | 97.9% | 100.0% |
| 3tqtB01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 45.0 | 4.26e-01 | 97.9% | 76.5% |
| 4j3cA01 | 2.40.240.20 | Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Hypothetical PUA domain-like; domain 1 | 0.53 | 34.0 | 3.87e-01 | 82.1% | 96.9% |
| 2ew0A00 | 3.40.1740.10 | Alpha Beta › 3-Layer(aba) Sandwich › VC0467-like › VC0467-like | 0.53 | 40.0 | 3.30e-01 | 81.1% | 65.1% |
| 2yhaA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 44.0 | 3.36e-01 | 93.7% | 68.6% |
| 2xp1A02 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.52 | 39.0 | 4.16e-01 | 92.6% | 93.8% |
| 2hqsA01 | 3.40.50.10070 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TolB, N-terminal domain | 0.52 | 46.0 | 4.08e-01 | 100.0% | 89.4% |
| 7x0fA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.51 | 44.0 | 3.82e-01 | 94.7% | 70.3% |
| 3otxB01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.51 | 44.0 | 3.20e-01 | 96.8% | 55.6% |
| 1i72A00 | 3.60.90.10 | Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase | 0.51 | 40.0 | 3.02e-01 | 86.3% | 96.4% |
| 3ktzA01 | 3.40.420.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ricin (A subunit); domain 1 › Ricin (A subunit), domain 1 | 0.50 | 41.0 | 3.50e-01 | 92.6% | 81.0% |
| 2hxsA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 44.0 | 3.64e-01 | 100.0% | 93.8% |
| 2gs5A01 | 3.40.1740.10 | Alpha Beta › 3-Layer(aba) Sandwich › VC0467-like › VC0467-like | 0.50 | 38.0 | 3.10e-01 | 82.1% | 61.7% |
| 1zhvA00 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.50 | 43.0 | 3.87e-01 | 95.8% | 90.3% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5053873 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.64 | 57.0 | 5.56e-01 | 98.9% | 90.5% |
| 3546715 | 5104.1.1.3 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 | 0.64 | 57.0 | 5.05e-01 | 100.0% | 85.0% |
| 5027632 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.63 | 56.0 | 5.12e-01 | 98.9% | 84.8% |
| 4975955 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.63 | 56.0 | 5.06e-01 | 98.9% | 84.6% |
| 5030203 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.63 | 56.0 | 5.06e-01 | 98.9% | 84.6% |
| 5066835 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.63 | 55.0 | 5.02e-01 | 98.9% | 83.1% |
| 3588369 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.63 | 56.0 | 5.18e-01 | 100.0% | 80.8% |
| 4956569 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.62 | 55.0 | 5.19e-01 | 98.9% | 88.7% |
| 4935393 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.62 | 55.0 | 4.98e-01 | 98.9% | 82.9% |
| 5074659 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.62 | 54.0 | 4.89e-01 | 98.9% | 81.5% |
| 3965775 | 4045.1.1.1 ↗ | a+b two layers › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › Aminotran_4 | 0.61 | 53.0 | 4.76e-01 | 97.9% | 95.5% |
| 5044654 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.59 | 52.0 | 4.97e-01 | 100.0% | 92.2% |
| 3322500 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.59 | 45.0 | 3.14e-01 | 82.1% | 54.6% |
| 3255906 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.58 | 52.0 | 4.45e-01 | 98.9% | 82.7% |
| 3475000 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 51.0 | 3.91e-01 | 100.0% | 97.8% |
| 4539032 | 314.1.1.11 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta | 0.58 | 48.0 | 4.03e-01 | 93.7% | 90.9% |
| 385837 | 4045.1.1.1 ↗ | a+b two layers › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › Aminotran_4 | 0.57 | 48.0 | 4.15e-01 | 96.8% | 78.6% |
| 3636393 | 304.8.1.6 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_3 | 0.56 | 32.0 | 4.02e-01 | 86.3% | 96.4% |
| 5079182 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.56 | 48.0 | 4.51e-01 | 100.0% | 87.0% |
| 2531242 | 2006.1.6.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like | 0.55 | 49.0 | 3.18e-01 | 95.8% | 60.4% |
| 3698900 | 219.1.1.16 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 | 0.55 | 46.0 | 3.40e-01 | 98.9% | 59.7% |
| 9524 | 2003.6.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB | 0.55 | 47.0 | 3.22e-01 | 94.7% | 48.8% |
| 4992016 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.54 | 48.0 | 4.30e-01 | 100.0% | 70.3% |
| 4068264 | 323.1.1.5 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation | 0.54 | 44.0 | 3.44e-01 | 94.7% | 41.5% |
| 4013685 | 7504.1.1.0 ↗ | a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like | 0.54 | 47.0 | 3.87e-01 | 98.9% | 95.6% |
| 3881114 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.54 | 45.0 | 3.40e-01 | 93.7% | 78.3% |
| 3224367 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.53 | 39.0 | 2.77e-01 | 78.9% | 64.1% |
| 3623194 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.53 | 45.0 | 3.22e-01 | 94.7% | 71.9% |
| 3742541 | 2003.6.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB | 0.53 | 47.0 | 3.19e-01 | 100.0% | 47.7% |
| 4204908 | 323.1.1.5 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation | 0.52 | 44.0 | 3.41e-01 | 98.9% | 41.4% |
| 5049077 | 2004.1.1.16 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf | 0.52 | 45.0 | 3.51e-01 | 100.0% | 89.5% |
| 677 | 4113.1.1.1 ↗ | beta barrels › VC0467-like › VC0467-like › VC0467-like › DUF179 | 0.50 | 38.0 | 3.08e-01 | 82.1% | 60.1% |
| 3601540 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.50 | 43.0 | 3.52e-01 | 97.9% | 77.9% |
| 1188317 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.50 | 43.0 | 3.39e-01 | 100.0% | 67.0% |