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IMGVR_UViG_3300021509_000009-3300021509-Ga0190304_10001353

Arc-Vir

IMGVR_UViG_3300021509_000009-3300021509-Ga0190304_10001353

Quality

86.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-56
PDB
Domain cluster: representative
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1j78A05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.81 60.0 5.87e-01 82.1% 73.3%
6ofuA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.79 68.0 4.34e-01 94.6% 91.1%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.78 58.0 4.31e-01 80.4% 33.1%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 54.0 5.43e-01 75.0% 73.2%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.76 61.0 6.07e-01 85.7% 91.2%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 56.0 3.87e-01 78.6% 80.7%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.75 62.0 5.01e-01 94.6% 48.1%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.74 66.0 4.88e-01 100.0% 45.1%
4oogC01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.74 65.0 4.68e-01 100.0% 48.8%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.74 60.0 4.26e-01 89.3% 57.9%
3d5lA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 50.0 5.21e-01 75.0% 78.8%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.73 56.0 5.10e-01 80.4% 66.2%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 55.0 5.01e-01 80.4% 64.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 55.0 3.53e-01 80.4% 19.9%
1o0wA01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.72 63.0 4.62e-01 100.0% 57.1%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.72 63.0 4.69e-01 100.0% 58.6%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 54.0 4.46e-01 80.4% 63.3%
6fakA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.71 51.0 4.36e-01 78.6% 46.3%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 52.0 3.76e-01 78.6% 65.3%
1fcqA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.70 60.0 3.78e-01 100.0% 21.3%
7cyuA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.69 49.0 4.89e-01 94.6% 73.7%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.69 57.0 4.11e-01 100.0% 34.1%
2eb1C00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.68 59.0 4.25e-01 100.0% 42.0%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.68 50.0 4.60e-01 78.6% 61.4%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.68 54.0 4.88e-01 92.9% 62.8%
7ar7E01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.66 42.0 4.10e-01 73.2% 57.1%
2j5iA02 6.10.250.2850 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 43.0 5.00e-01 71.4% 100.0%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.66 51.0 4.15e-01 94.6% 44.0%
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.64 44.0 3.44e-01 71.4% 64.1%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.63 55.0 4.86e-01 100.0% 70.6%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.63 55.0 3.58e-01 100.0% 22.9%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 56.0 4.15e-01 100.0% 75.0%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 58.0 4.89e-01 100.0% 64.8%
4gf0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 45.0 3.62e-01 80.4% 38.1%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 49.0 4.05e-01 89.3% 48.0%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 55.0 3.82e-01 100.0% 54.5%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.62 46.0 4.13e-01 89.3% 54.7%
4ixjA01 3.30.1300.80 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.62 46.0 4.24e-01 83.9% 67.5%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.61 51.0 4.25e-01 94.6% 52.5%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 49.0 4.52e-01 87.5% 69.4%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.60 45.0 4.29e-01 100.0% 67.7%
2fh5A01 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.59 45.0 3.56e-01 89.3% 38.5%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.58 48.0 3.52e-01 100.0% 31.8%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.55 47.0 3.76e-01 92.9% 72.9%
1kl9A02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.54 40.0 3.59e-01 87.5% 64.1%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.54 50.0 3.25e-01 100.0% 50.4%
1vf6C00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.51 39.0 3.97e-01 98.2% 98.0%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.51 41.0 3.55e-01 89.3% 57.6%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3628140 3826.1.1.43 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Med14 0.87 60.0 4.64e-01 73.2% 36.4%
3588971 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.81 70.0 6.44e-01 100.0% 78.7%
3474600 4207.1.2.48 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med14 0.80 60.0 4.85e-01 80.4% 44.0%
5078040 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.80 71.0 6.17e-01 100.0% 65.9%
4983608 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 67.0 6.39e-01 100.0% 80.0%
3284949 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.78 68.0 6.31e-01 96.4% 95.7%
3972992 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 56.0 5.35e-01 75.0% 64.6%
3235805 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.78 52.0 5.87e-01 71.4% 97.5%
3268369 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.77 67.0 5.58e-01 96.4% 66.3%
5054424 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.76 65.0 5.76e-01 94.6% 68.8%
3597348 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.75 65.0 4.06e-01 100.0% 18.4%
5069130 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.75 59.0 6.20e-01 89.3% 100.0%
4959191 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.75 64.0 5.46e-01 94.6% 60.0%
3940867 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.74 61.0 5.18e-01 100.0% 54.7%
3720522 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.73 56.0 3.66e-01 85.7% 22.7%
5077996 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.73 63.0 3.98e-01 100.0% 19.7%
1108030 171.1.1.1 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.72 63.0 4.53e-01 100.0% 50.9%
3182867 2006.1.4.33 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › Tim17 0.72 61.0 5.56e-01 100.0% 95.0%
4034454 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.72 60.0 4.80e-01 100.0% 44.8%
3967043 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.72 62.0 5.28e-01 100.0% 60.0%
4025205 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.71 59.0 4.24e-01 89.3% 36.7%
4594578 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.71 52.0 4.26e-01 87.5% 45.3%
4323124 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.70 56.0 3.41e-01 92.9% 14.5%
3591755 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 54.0 4.61e-01 89.3% 52.2%
3785363 3831.1.1.0 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.69 61.0 5.02e-01 98.2% 73.0%
4652188 171.1.1.1 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.68 59.0 4.43e-01 98.2% 48.3%
3410128 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.68 56.0 5.33e-01 87.5% 80.0%
5051837 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 60.0 4.06e-01 98.2% 42.6%
3257705 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.67 55.0 4.53e-01 87.5% 53.7%
3210666 3559.1.1.35 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mis12 0.67 59.0 4.87e-01 100.0% 59.0%
5036615 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.66 59.0 4.96e-01 100.0% 58.9%
3317016 150.5.1.102 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF28483 0.66 57.0 5.32e-01 94.6% 80.9%
3278450 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.66 58.0 5.16e-01 100.0% 73.8%
4913800 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.66 53.0 4.83e-01 92.9% 74.7%
3838316 3567.1.1.150 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › H-kinase_dim 0.66 52.0 4.68e-01 83.9% 69.3%
4327215 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.65 57.0 4.55e-01 100.0% 51.3%
3180974 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.65 53.0 5.39e-01 100.0% 89.1%
4417777 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.65 56.0 4.36e-01 100.0% 45.4%
None 0.65 56.0 3.62e-01 100.0% 21.9%
4980095 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.65 59.0 4.69e-01 100.0% 52.4%
3586032 605.1.1.237 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Patched 0.65 56.0 4.60e-01 100.0% 70.5%
2142296 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.65 51.0 4.09e-01 83.9% 46.9%
3588172 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.64 57.0 4.10e-01 96.4% 86.0%
3486786 165.3.1.0 alpha duplicates or obligate multimers › Dimerisation interlock › Phenylalanine zipper › Phenylalanine zipper 0.63 48.0 4.91e-01 91.1% 92.7%
4613072 101.1.2.721 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27113 0.62 55.0 3.83e-01 94.6% 32.1%
4877579 605.3.1.1 alpha duplicates or obligate multimers › ROP-like › Nonstructural protein ns2, Nep, M1-binding domain › Nonstructural protein ns2, Nep, M1-binding domain › Flu_NS2 0.59 52.0 5.31e-01 94.6% 96.4%
4974349 225.1.1.41 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HisKA_2 0.58 43.0 3.22e-01 87.5% 98.2%
5002533 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.54 46.0 3.84e-01 100.0% 64.8%
4287168 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.53 46.0 2.68e-01 94.6% 49.4%