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IMGVR_UViG_3300022161_001637-3300022161-Ga0213931_10010881
Arc-VirIMGVR_UViG_3300022161_001637-3300022161-Ga0213931_10010881
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 27-180
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 243.2 | 7.00e-72 | 94.2% | 33.4% |
D2
high
residues 368-463
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 61.6 | 9.50e-17 | 100.0% | 20.6% |
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zvuA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.98 | 92.0 | 7.85e-01 | 100.0% | 66.4% |
| 3lpxA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.94 | 85.0 | 8.26e-01 | 93.8% | 100.0% |
| 4z4qA04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.90 | 80.0 | 8.31e-01 | 92.7% | 100.0% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.90 | 48.0 | 5.48e-01 | 100.0% | 69.3% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 50.0 | 3.99e-01 | 100.0% | 32.0% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.84 | 40.0 | 3.79e-01 | 100.0% | 39.8% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 49.0 | 4.77e-01 | 100.0% | 53.8% |
| 8gccA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.83 | 75.0 | 7.29e-01 | 95.8% | 94.2% |
| 1bgwA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.83 | 74.0 | 7.07e-01 | 95.8% | 100.0% |
| 3qx3A04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.81 | 71.0 | 7.07e-01 | 93.8% | 100.0% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.80 | 47.0 | 4.05e-01 | 100.0% | 39.7% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 49.0 | 6.00e-01 | 100.0% | 100.0% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.77 | 48.0 | 4.91e-01 | 100.0% | 64.2% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.77 | 45.0 | 3.89e-01 | 100.0% | 39.2% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.76 | 41.0 | 4.39e-01 | 93.8% | 60.7% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.76 | 39.0 | 4.24e-01 | 100.0% | 59.3% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 41.0 | 4.62e-01 | 96.9% | 69.3% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 47.0 | 4.14e-01 | 96.9% | 45.9% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 44.0 | 3.92e-01 | 100.0% | 44.6% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.73 | 48.0 | 4.83e-01 | 100.0% | 67.0% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 43.0 | 3.41e-01 | 100.0% | 31.3% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.70 | 37.0 | 3.57e-01 | 100.0% | 43.6% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.69 | 44.0 | 3.59e-01 | 100.0% | 35.2% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 44.0 | 4.11e-01 | 100.0% | 52.9% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 45.0 | 3.97e-01 | 99.0% | 46.5% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 39.0 | 3.59e-01 | 100.0% | 43.4% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.68 | 44.0 | 4.07e-01 | 100.0% | 53.8% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.66 | 44.0 | 3.05e-01 | 100.0% | 21.2% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 43.0 | 3.31e-01 | 100.0% | 29.3% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.65 | 43.0 | 3.61e-01 | 100.0% | 39.8% |
| 1gnlA01 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 40.0 | 3.50e-01 | 94.8% | 42.4% |
| 4nx9A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.61 | 55.0 | 4.67e-01 | 99.0% | 100.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 42.0 | 4.67e-01 | 100.0% | 97.2% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.58 | 39.0 | 4.02e-01 | 97.9% | 72.2% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 40.0 | 3.94e-01 | 100.0% | 66.7% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 38.0 | 2.83e-01 | 100.0% | 25.7% |
| 2iz1A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.57 | 49.0 | 3.70e-01 | 99.0% | 37.3% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.57 | 48.0 | 4.79e-01 | 99.0% | 86.0% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 42.0 | 3.65e-01 | 78.1% | 71.8% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 43.0 | 3.73e-01 | 80.2% | 72.3% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.56 | 50.0 | 4.59e-01 | 100.0% | 90.4% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 52.0 | 3.79e-01 | 100.0% | 39.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.55 | 46.0 | 4.35e-01 | 89.6% | 100.0% |
| 1oj6A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 34.0 | 2.96e-01 | 100.0% | 40.1% |
| 4dveA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.55 | 38.0 | 3.08e-01 | 72.9% | 55.6% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 45.0 | 4.07e-01 | 90.6% | 76.7% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.54 | 46.0 | 3.26e-01 | 96.9% | 78.2% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 47.0 | 3.84e-01 | 97.9% | 99.5% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.53 | 36.0 | 4.03e-01 | 100.0% | 91.9% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.53 | 48.0 | 4.22e-01 | 100.0% | 77.3% |
| 5mmjn01 | 1.10.287.1480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 34.0 | 3.53e-01 | 79.2% | 70.8% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 48.0 | 3.97e-01 | 100.0% | 65.9% |
| 3ajwA00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 49.0 | 4.31e-01 | 100.0% | 71.6% |
| 2xzeB00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.52 | 48.0 | 4.15e-01 | 96.9% | 81.2% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.52 | 47.0 | 4.57e-01 | 100.0% | 92.4% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.51 | 44.0 | 4.42e-01 | 100.0% | 93.0% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.50 | 44.0 | 3.72e-01 | 97.9% | 99.4% |
ECOD (82)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5062336 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 1.00 | 98.0 | 7.81e-01 | 100.0% | 83.0% |
| 4043618 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 1.00 | 98.0 | 8.07e-01 | 100.0% | 64.0% |
| 3345589 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.99 | 97.0 | 7.35e-01 | 100.0% | 51.1% |
| 5083298 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.99 | 96.0 | 7.99e-01 | 100.0% | 64.0% |
| 4373100 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.99 | 96.0 | 8.09e-01 | 100.0% | 66.2% |
| 4946213 | 4016.1.1.18 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_gyraseA_C | 0.99 | 96.0 | 8.08e-01 | 100.0% | 66.2% |
| 5024978 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.98 | 96.0 | 8.05e-01 | 100.0% | 66.2% |
| 4299749 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.98 | 96.0 | 8.04e-01 | 100.0% | 66.2% |
| 4932829 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.98 | 95.0 | 8.02e-01 | 100.0% | 66.2% |
| 4552385 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.97 | 91.0 | 7.49e-01 | 100.0% | 60.0% |
| 4855518 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.96 | 93.0 | 7.27e-01 | 100.0% | 73.0% |
| 1297277 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 93.0 | 7.22e-01 | 100.0% | 53.0% |
| 4218225 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 92.0 | 7.58e-01 | 100.0% | 61.9% |
| 4174306 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.95 | 89.0 | 7.41e-01 | 100.0% | 62.0% |
| 3959880 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.95 | 84.0 | 8.70e-01 | 91.7% | 97.8% |
| 1780091 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 90.0 | 7.39e-01 | 100.0% | 60.8% |
| 3965596 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 90.0 | 7.05e-01 | 100.0% | 73.3% |
| 4883080 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.91 | 86.0 | 7.56e-01 | 100.0% | 71.6% |
| 1302406 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.89 | 84.0 | 7.11e-01 | 100.0% | 65.3% |
| 3526459 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.89 | 48.0 | 3.46e-01 | 100.0% | 22.1% |
| 4024264 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.85 | 79.0 | 6.98e-01 | 100.0% | 71.1% |
| 5047149 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.84 | 50.0 | 4.00e-01 | 100.0% | 33.5% |
| 3508111 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.83 | 78.0 | 6.18e-01 | 100.0% | 75.6% |
| 3708939 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.81 | 75.0 | 6.30e-01 | 100.0% | 61.9% |
| 5058485 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.81 | 46.0 | 4.36e-01 | 100.0% | 47.8% |
| 3634044 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.81 | 75.0 | 5.86e-01 | 100.0% | 67.9% |
| 3600354 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.81 | 74.0 | 6.30e-01 | 99.0% | 63.3% |
| 3939260 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.78 | 51.0 | 5.04e-01 | 100.0% | 63.0% |
| 4451459 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.77 | 49.0 | 4.43e-01 | 100.0% | 49.6% |
| 5047089 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 44.0 | 4.27e-01 | 100.0% | 52.7% |
| 3830963 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.70 | 41.0 | 3.83e-01 | 100.0% | 46.7% |
| 3580283 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 42.0 | 4.46e-01 | 100.0% | 69.4% |
| 3819179 | 632.7.1.62 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF641 | 0.68 | 36.0 | 3.19e-01 | 100.0% | 34.3% |
| 4967067 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 41.0 | 3.90e-01 | 100.0% | 52.2% |
| 5012659 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.65 | 42.0 | 4.17e-01 | 93.8% | 63.0% |
| 5031064 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 38.0 | 3.79e-01 | 100.0% | 55.0% |
| 3348202 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.60 | 55.0 | 4.14e-01 | 100.0% | 82.2% |
| 4589614 | 5051.1.1.7 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp | 0.59 | 52.0 | 3.49e-01 | 100.0% | 74.9% |
| 3816459 | 3684.1.1.10 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 | 0.59 | 53.0 | 4.21e-01 | 99.0% | 97.4% |
| 3590361 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 54.0 | 4.19e-01 | 100.0% | 91.5% |
| 4374987 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 53.0 | 4.21e-01 | 100.0% | 94.9% |
| 4995143 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 52.0 | 4.14e-01 | 100.0% | 93.8% |
| 3932178 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.58 | 46.0 | 4.08e-01 | 100.0% | 58.6% |
| 3245293 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 52.0 | 3.98e-01 | 100.0% | 89.3% |
| 3692427 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 50.0 | 3.73e-01 | 100.0% | 91.6% |
| 4944363 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 51.0 | 3.80e-01 | 100.0% | 81.3% |
| 3516214 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 37.0 | 3.85e-01 | 99.0% | 72.2% |
| 3635128 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 52.0 | 3.82e-01 | 100.0% | 51.2% |
| 5026210 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 50.0 | 3.98e-01 | 100.0% | 90.0% |
| 4978686 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 49.0 | 3.99e-01 | 100.0% | 94.8% |
| 3687819 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.55 | 49.0 | 3.64e-01 | 100.0% | 80.0% |
| 4985518 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 49.0 | 4.00e-01 | 100.0% | 97.3% |
| 5044365 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 49.0 | 3.93e-01 | 100.0% | 95.9% |
| 3566743 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 50.0 | 3.64e-01 | 100.0% | 69.0% |
| 3515796 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 46.0 | 3.87e-01 | 100.0% | 52.9% |
| 3267295 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 48.0 | 3.79e-01 | 100.0% | 73.8% |
| 5076969 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 49.0 | 3.88e-01 | 100.0% | 96.9% |
| 3341433 | 604.12.1.77 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PMEI | 0.54 | 37.0 | 3.74e-01 | 95.8% | 70.5% |
| 5006733 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 49.0 | 3.90e-01 | 100.0% | 91.6% |
| 5069593 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 48.0 | 3.86e-01 | 100.0% | 92.3% |
| 3973779 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 47.0 | 3.78e-01 | 100.0% | 90.5% |
| 3925108 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 48.0 | 3.71e-01 | 100.0% | 85.5% |
| 5039668 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 48.0 | 3.85e-01 | 100.0% | 94.7% |
| 4262528 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 46.0 | 3.68e-01 | 100.0% | 91.2% |
| 5024431 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 46.0 | 3.78e-01 | 99.0% | 98.9% |
| 5049262 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 46.0 | 3.68e-01 | 96.9% | 94.4% |
| 4970934 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 3.66e-01 | 100.0% | 91.7% |
| 4261753 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 3.79e-01 | 100.0% | 98.4% |
| 3889547 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 49.0 | 3.82e-01 | 100.0% | 52.6% |
| 4934758 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 47.0 | 3.78e-01 | 97.9% | 68.3% |
| 3721623 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.52 | 48.0 | 4.09e-01 | 100.0% | 90.7% |
| 5037043 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 3.65e-01 | 100.0% | 92.0% |
| 3718609 | 109.4.1.726 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DHC_N1 | 0.51 | 48.0 | 3.48e-01 | 100.0% | 49.4% |
| 5030340 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 42.0 | 3.47e-01 | 90.6% | 66.1% |
| 3781812 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 45.0 | 3.56e-01 | 100.0% | 90.0% |
| 5026259 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 44.0 | 3.50e-01 | 96.9% | 94.0% |
| 3774121 | 150.1.1.119 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Clusterin | 0.51 | 47.0 | 3.91e-01 | 100.0% | 64.4% |
| 3413723 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 36.0 | 3.57e-01 | 75.0% | 89.5% |
| 3695398 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.51 | 44.0 | 3.39e-01 | 100.0% | 90.2% |
| 3937868 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.50 | 43.0 | 3.22e-01 | 96.9% | 92.2% |
| 3854995 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.50 | 46.0 | 3.33e-01 | 100.0% | 47.5% |
| 4935179 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 42.0 | 3.33e-01 | 90.6% | 60.5% |
D3
high
residues 501-633
Domain cluster:
rep: AJ972879.2__CCE26352.1__X__00330__D428-542
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03989.19 best | DNA_gyraseA_C | 43.7 | 2.00e-11 | 37.6% | 81.2% |
| PF03989.19 | DNA_gyraseA_C | 44.1 | 1.50e-11 | 36.1% | 89.6% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3uc1A00 | 2.120.10.90 | Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal | 0.87 | 76.0 | 5.63e-01 | 96.2% | 40.3% |
| 1wp5A00 | 2.120.10.90 | Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal | 0.84 | 75.0 | 5.48e-01 | 99.2% | 38.8% |
| 3l6vA00 | 2.120.10.90 | Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal | 0.82 | 76.0 | 5.55e-01 | 96.2% | 41.2% |
| 1suuA00 | 2.120.10.90 | Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal | 0.77 | 67.0 | 5.11e-01 | 94.7% | 42.0% |
| 3no0A00 | 2.120.10.90 | Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal | 0.77 | 66.0 | 5.12e-01 | 94.7% | 43.8% |
| 2yn5A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.58 | 32.0 | 4.05e-01 | 80.5% | 89.9% |
| 6m3aA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.58 | 28.0 | 3.88e-01 | 75.2% | 93.9% |
| 1qr4A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 31.0 | 3.69e-01 | 77.4% | 86.2% |
| 1qcsA01 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.53 | 32.0 | 3.88e-01 | 71.4% | 96.3% |
| 1hskA01 | 3.30.465.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › | 0.51 | 30.0 | 3.06e-01 | 77.4% | 58.3% |
| 5jzxD02 | 3.30.465.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › | 0.50 | 29.0 | 2.83e-01 | 77.4% | 49.3% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4261933 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.96 | 94.0 | 6.74e-01 | 100.0% | 41.9% |
| 3445642 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.96 | 93.0 | 6.57e-01 | 100.0% | 38.8% |
| 3959000 | 5.2.1.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel | 0.95 | 92.0 | 7.61e-01 | 100.0% | 64.1% |
| 5040277 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.94 | 91.0 | 6.55e-01 | 100.0% | 41.8% |
| 4602375 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.94 | 91.0 | 6.42e-01 | 100.0% | 38.3% |
| 4589818 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.94 | 87.0 | 6.40e-01 | 96.2% | 42.3% |
| 5053478 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.92 | 88.0 | 6.42e-01 | 100.0% | 42.5% |
| 4331124 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.91 | 87.0 | 6.09e-01 | 100.0% | 37.5% |
| 4271590 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.91 | 87.0 | 6.31e-01 | 100.0% | 42.2% |
| 4279289 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.90 | 87.0 | 6.26e-01 | 100.0% | 41.2% |
| 4075947 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.90 | 78.0 | 6.28e-01 | 99.2% | 51.1% |
| 4505869 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.90 | 86.0 | 6.25e-01 | 100.0% | 42.5% |
| 4186650 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.90 | 83.0 | 6.08e-01 | 97.0% | 41.4% |
| 4074611 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.88 | 81.0 | 5.95e-01 | 96.2% | 41.4% |
| 4946214 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.88 | 84.0 | 6.07e-01 | 100.0% | 41.5% |
| 4102294 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.88 | 84.0 | 6.13e-01 | 100.0% | 42.2% |
| 4150603 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.88 | 81.0 | 5.92e-01 | 97.0% | 41.2% |
| 4410663 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.88 | 77.0 | 6.10e-01 | 100.0% | 50.4% |
| 5007962 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.87 | 81.0 | 6.12e-01 | 97.7% | 44.8% |
| 4388717 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.87 | 84.0 | 6.11e-01 | 100.0% | 42.5% |
| 4429482 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.87 | 83.0 | 5.98e-01 | 100.0% | 40.9% |
| 4569696 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.87 | 83.0 | 6.03e-01 | 100.0% | 42.2% |
| 4935505 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.86 | 79.0 | 5.81e-01 | 96.2% | 41.6% |
| 4028934 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.86 | 72.0 | 5.41e-01 | 100.0% | 39.7% |
| 4606923 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.85 | 81.0 | 5.87e-01 | 100.0% | 40.9% |
| 5082153 | 5.2.1.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel | 0.85 | 77.0 | 5.66e-01 | 94.7% | 41.3% |
| 4493828 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.85 | 73.0 | 5.48e-01 | 94.7% | 41.0% |
| 4250515 | 5.2.1.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel | 0.84 | 72.0 | 5.69e-01 | 99.2% | 47.6% |
| 2179 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.84 | 75.0 | 5.50e-01 | 99.2% | 39.0% |
| 4609257 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.83 | 74.0 | 5.46e-01 | 98.5% | 38.9% |
| 3164811 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.83 | 72.0 | 5.67e-01 | 100.0% | 47.5% |
| 4177906 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.81 | 73.0 | 5.43e-01 | 95.5% | 42.3% |
| 5059693 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.80 | 72.0 | 5.39e-01 | 95.5% | 42.0% |
| 5024979 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.79 | 75.0 | 5.55e-01 | 100.0% | 43.9% |
| 4214118 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.79 | 68.0 | 5.25e-01 | 94.7% | 43.4% |
| 4421198 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.77 | 65.0 | 5.55e-01 | 94.7% | 57.6% |
| 3969629 | 5.2.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C | 0.72 | 64.0 | 5.12e-01 | 96.2% | 66.3% |
| 2526350 | 1.17.1.0 ↗ | beta barrels › cradle loop barrel | 0.66 | 36.0 | 4.70e-01 | 73.7% | 94.7% |
| 5034410 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 33.0 | 3.77e-01 | 77.4% | 82.0% |
| 3528768 | 11.1.1.2 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 | 0.52 | 30.0 | 3.51e-01 | 77.4% | 81.1% |
| 3893503 | 11.1.1.2 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 | 0.52 | 31.0 | 3.58e-01 | 79.7% | 79.0% |
| 3740728 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.51 | 33.0 | 3.97e-01 | 72.2% | 100.0% |
| 3267164 | 11.1.1.793 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7743 | 0.51 | 32.0 | 3.53e-01 | 82.7% | 79.0% |
D4
medium
residues 213-354
Domain cluster:
rep: DNA_topoisomerase_2__YP_003986988__Acanthamoeba_polyphaga_mimivirus__212035__D908-982_1022-1083
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 130.6 | 1.00e-37 | 100.0% | 31.3% |