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IMGVR_UViG_3300022916_000637-3300022916-Ga0233431_100183123
Arc-VirIMGVR_UViG_3300022916_000637-3300022916-Ga0233431_100183123
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-145
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 86.0 | 3.70e-24 | 87.4% | 31.1% |
D2
high
residues 162-292
Domain cluster:
representative
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4624017 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.86 | 81.0 | 7.20e-01 | 100.0% | 82.2% |
| 2140592 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.84 | 79.0 | 6.94e-01 | 100.0% | 82.4% |
| 3277529 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.76 | 71.0 | 6.56e-01 | 100.0% | 82.5% |
| 4943247 | 4955.1.1.12 ↗ | a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.63 | 42.0 | 5.04e-01 | 96.9% | 100.0% |
| 4974156 | 241.11.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › YjbR-like › YjbR-like | 0.62 | 34.0 | 3.89e-01 | 70.2% | 71.0% |
| 4464027 | 241.1.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone | 0.56 | 38.0 | 4.07e-01 | 70.2% | 81.7% |
| 4999340 | 241.11.1.6 ↗ | a+b two layers › Type III secretory system chaperone-like › YjbR-like › YjbR-like › TfoX_N | 0.54 | 36.0 | 4.04e-01 | 78.6% | 89.0% |
| 3267771 | 4099.1.1.0 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like | 0.54 | 38.0 | 4.09e-01 | 73.3% | 86.4% |
| 3516513 | 109.2.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid | 0.51 | 41.0 | 2.56e-01 | 86.3% | 31.6% |
D3
high
residues 315-444
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5umbA02 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.70 | 28.0 | 3.70e-01 | 100.0% | 65.3% |
| 3venA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.68 | 32.0 | 2.67e-01 | 70.0% | 25.4% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 36.0 | 3.77e-01 | 95.4% | 60.8% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.62 | 45.0 | 4.78e-01 | 96.2% | 83.5% |
| 1y0hB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 34.0 | 3.85e-01 | 85.4% | 74.5% |
| 3fgvA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 30.0 | 3.50e-01 | 87.7% | 76.3% |
| 1x8dA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 30.0 | 3.42e-01 | 82.3% | 76.3% |
| 5dymA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 36.0 | 4.10e-01 | 74.6% | 100.0% |
| 2fdoA00 | 3.30.1970.10 | Alpha Beta › 2-Layer Sandwich › AF2331-like fold › AF2331-like | 0.51 | 21.0 | 2.42e-01 | 84.6% | 45.2% |
| 6vq6H01 | 1.10.287.3240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 45.0 | 3.82e-01 | 95.4% | 87.7% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4012069 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 47.0 | 4.33e-01 | 92.3% | 51.2% |
| 3170708 | 632.1.1.6 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Pho88 | 0.67 | 36.0 | 3.47e-01 | 100.0% | 46.2% |
| 3276180 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.64 | 59.0 | 5.12e-01 | 100.0% | 82.1% |
| 2391543 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.63 | 42.0 | 3.61e-01 | 95.4% | 44.7% |
| 3221653 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.63 | 39.0 | 2.74e-01 | 93.1% | 20.8% |
| 3939245 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.63 | 41.0 | 2.97e-01 | 100.0% | 24.2% |
| 3718739 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.62 | 57.0 | 5.24e-01 | 100.0% | 84.2% |
| 5023832 | 331.2.1.0 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain | 0.61 | 33.0 | 4.18e-01 | 81.5% | 90.7% |
| 3289101 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.61 | 17.0 | 2.88e-01 | 88.5% | 68.0% |
| 3574069 | 604.12.1.62 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DuoxA | 0.60 | 35.0 | 3.56e-01 | 93.1% | 57.6% |
| 3628638 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.60 | 40.0 | 3.01e-01 | 94.6% | 27.3% |
| 3221030 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.58 | 41.0 | 3.14e-01 | 99.2% | 32.0% |
| 4970576 | 375.1.1.179 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha | 0.58 | 36.0 | 3.26e-01 | 93.1% | 45.0% |
| 3925086 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.57 | 43.0 | 3.08e-01 | 96.2% | 28.5% |
| 4221024 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 35.0 | 3.03e-01 | 96.2% | 39.0% |
| 5031648 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.56 | 35.0 | 3.23e-01 | 95.4% | 48.5% |
| 3603448 | 3291.1.1.49 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › NFACT_N | 0.56 | 50.0 | 4.64e-01 | 98.5% | 94.5% |
| 3899483 | 3226.1.1.3 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp | 0.54 | 44.0 | 2.92e-01 | 86.9% | 71.7% |
| 3739576 | 327.11.2.27 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_Vigilin | 0.54 | 25.0 | 3.51e-01 | 89.2% | 100.0% |
| 4139587 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.53 | 27.0 | 3.22e-01 | 70.8% | 71.8% |
| 5055279 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.53 | 38.0 | 3.33e-01 | 75.4% | 81.0% |
| 4068249 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.53 | 30.0 | 3.59e-01 | 82.3% | 87.5% |
| 4994522 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 47.0 | 4.43e-01 | 100.0% | 91.9% |
| 3839430 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.50 | 27.0 | 3.31e-01 | 81.5% | 85.3% |
| 5026457 | 3926.1.1.1 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D | 0.50 | 45.0 | 3.86e-01 | 98.5% | 87.0% |