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IMGVR_UViG_3300024258_000512-3300024258-Ga0233440_10080046

Arc-Vir

IMGVR_UViG_3300024258_000512-3300024258-Ga0233440_10080046

Quality

60.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-52
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jquB00 1.10.287.4310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 43.0 4.09e-01 89.1% 59.3%
2odaA00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.61 49.0 3.26e-01 89.1% 97.4%
1sigA00 1.10.601.10 Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor 0.58 45.0 2.81e-01 93.5% 13.8%
4xukA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.58 47.0 2.91e-01 93.5% 78.4%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3997665 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.67 47.0 3.46e-01 91.3% 30.1%
4952130 3714.1.1.1 a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › LonC_helical 0.61 49.0 3.06e-01 87.0% 21.7%
4933265 5060.1.1.1 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.51 41.0 2.97e-01 100.0% 58.1%
D2 high residues 489-586
PDB
D3 medium residues 57-181
PDB
Domain cluster: representative
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.68 52.0 3.78e-01 80.0% 81.3%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.68 54.0 4.90e-01 84.0% 88.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.65 48.0 5.05e-01 78.4% 93.0%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 50.0 4.62e-01 80.8% 83.5%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 47.0 4.67e-01 76.8% 93.9%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 53.0 4.58e-01 88.8% 88.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.63 48.0 4.57e-01 80.8% 74.8%
4k5yA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 47.0 3.74e-01 77.6% 58.9%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.63 44.0 3.30e-01 72.8% 52.4%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 47.0 4.63e-01 78.4% 97.0%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 47.0 4.56e-01 80.0% 92.3%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 47.0 3.98e-01 80.0% 61.6%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 47.0 4.62e-01 80.8% 86.8%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 54.0 4.54e-01 96.8% 85.4%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 47.0 4.24e-01 82.4% 93.5%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 44.0 4.45e-01 76.0% 93.4%
8g59R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 44.0 3.49e-01 76.8% 93.2%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.59 42.0 3.96e-01 100.0% 59.4%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 45.0 3.84e-01 84.0% 61.7%
1di1A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 41.0 3.22e-01 74.4% 86.6%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 42.0 4.60e-01 77.6% 94.1%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 42.0 4.47e-01 83.2% 88.0%
3dxqB02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.57 44.0 3.70e-01 81.6% 82.9%
2yn7A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.57 50.0 4.20e-01 96.8% 83.6%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 51.0 4.45e-01 100.0% 88.8%
1uzbA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.56 44.0 3.32e-01 84.8% 65.3%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.56 41.0 3.85e-01 76.8% 72.5%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.55 33.0 3.82e-01 87.2% 85.9%
3vvaA00 1.20.1260.140 Mainly Alpha › Up-down Bundle › Ferritin › Alternative oxidase 0.54 47.0 3.73e-01 96.0% 61.7%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 41.0 3.96e-01 95.2% 70.2%
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.54 32.0 3.92e-01 90.4% 93.8%
4o6mA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.54 42.0 3.69e-01 86.4% 54.4%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 38.0 3.77e-01 79.2% 70.8%
3kh1A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.53 47.0 4.10e-01 99.2% 93.3%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 48.0 4.50e-01 100.0% 98.1%
3nftA00 1.20.1710.10 Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like 0.52 46.0 3.65e-01 99.2% 73.3%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 45.0 4.21e-01 99.2% 96.8%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.50 46.0 3.88e-01 98.4% 89.1%
2diwA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 42.0 4.03e-01 93.6% 79.4%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3670390 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.72 55.0 4.26e-01 80.0% 78.5%
3491432 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.72 55.0 5.01e-01 80.8% 75.8%
3620913 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 54.0 4.67e-01 80.8% 95.4%
4949599 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.69 51.0 4.82e-01 76.0% 80.0%
4320989 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.67 51.0 5.27e-01 79.2% 100.0%
3475661 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.67 52.0 4.94e-01 80.8% 80.7%
3393338 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 52.0 4.90e-01 83.2% 80.4%
4027573 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.66 59.0 4.83e-01 98.4% 64.3%
3228302 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.66 48.0 4.95e-01 76.0% 97.5%
4023316 3755.4.1.5 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Dynactin 0.66 54.0 4.75e-01 87.2% 81.7%
3607681 633.10.1.15 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.65 50.0 4.92e-01 80.8% 85.9%
3504568 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.65 51.0 4.95e-01 83.2% 94.3%
3269163 150.1.1.31 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.65 49.0 3.82e-01 80.8% 83.8%
3831395 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.65 52.0 4.00e-01 85.6% 71.9%
3766796 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.64 53.0 5.08e-01 85.6% 83.6%
3807542 3684.1.1.10 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 0.63 52.0 3.82e-01 87.2% 78.7%
3644885 3758.1.1.31 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › DUF677 0.62 48.0 3.64e-01 81.6% 77.7%
3468403 601.1.2.74 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N 0.62 47.0 4.65e-01 79.2% 100.0%
3409618 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.62 48.0 3.61e-01 81.6% 74.6%
3666924 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.62 49.0 5.10e-01 84.8% 90.4%
3359287 611.7.1.14 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7792 0.62 50.0 4.55e-01 85.6% 84.8%
3485310 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.62 48.0 4.69e-01 83.2% 89.3%
3315232 611.7.1.8 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › RPW8 0.61 51.0 4.88e-01 87.2% 98.6%
5064471 601.4.1.88 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DDE_Tnp_IS66 0.61 51.0 5.31e-01 98.4% 100.0%
3311689 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.61 47.0 4.58e-01 81.6% 90.7%
3929351 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.61 48.0 2.98e-01 83.2% 62.5%
3191636 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.60 43.0 3.57e-01 74.4% 87.0%
3438770 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.60 48.0 4.36e-01 84.8% 80.0%
4182090 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.60 43.0 3.65e-01 75.2% 81.9%
4048446 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.60 43.0 3.54e-01 74.4% 84.3%
4825444 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.59 54.0 4.57e-01 100.0% 87.0%
3494149 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.59 45.0 4.11e-01 80.0% 78.8%
3886845 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 49.0 4.12e-01 89.6% 59.1%
3609309 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 54.0 4.36e-01 97.6% 64.4%
3697729 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.59 48.0 4.21e-01 86.4% 65.4%
3456024 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.59 47.0 4.51e-01 85.6% 84.8%
3463547 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.58 46.0 4.40e-01 85.6% 92.7%
3336494 611.7.1.2 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc 0.58 49.0 4.65e-01 92.0% 93.3%
4017700 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.58 46.0 4.61e-01 84.0% 93.6%
3356382 3543.1.1.4 alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF716 0.58 44.0 3.54e-01 81.6% 54.2%
4029481 7525.1.1.2 a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_2 0.57 43.0 3.02e-01 80.8% 23.8%
4015699 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.57 41.0 3.53e-01 74.4% 85.9%
3390472 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 44.0 4.04e-01 81.6% 84.8%
4280209 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.57 47.0 3.94e-01 89.6% 68.8%
3464571 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.56 43.0 3.50e-01 80.8% 60.4%
3390148 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.56 42.0 4.15e-01 77.6% 83.8%
3236694 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.55 47.0 4.52e-01 99.2% 82.1%
3970681 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 46.0 3.81e-01 98.4% 98.2%
3605421 1189.1.1.6 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ISG65-75 0.51 47.0 3.49e-01 99.2% 87.9%
3306059 3755.4.1.46 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A 0.50 42.0 3.37e-01 88.0% 69.4%
D4 medium residues 182-251
PDB
D5 medium residues 355-488
PDB