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IMGVR_UViG_3300024258_000828-3300024258-Ga0233440_100624416

Arc-Vir

IMGVR_UViG_3300024258_000828-3300024258-Ga0233440_100624416

Quality

96.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 99-109_218-313
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02773.22 best S-AdoMet_synt_C 72.5 4.70e-20 96.3% 74.6%
D2 high residues 115-190
PDB
Domain cluster: representative
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4odjA01 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.84 77.0 6.66e-01 98.7% 92.0%
3tufA00 1.10.287.4300 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Stage III sporulation protein AH-like 0.78 64.0 5.56e-01 98.7% 59.1%
1rm6A01 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.74 48.0 4.15e-01 77.6% 42.9%
2e8eA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.73 65.0 5.40e-01 98.7% 72.0%
1ml8A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.71 62.0 5.77e-01 98.7% 94.8%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.70 59.0 3.89e-01 94.7% 28.9%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.70 51.0 4.72e-01 76.3% 61.1%
4mh4A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.69 59.0 5.56e-01 96.1% 98.9%
3n2qA02 3.30.300.190 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.69 57.0 5.03e-01 93.4% 68.1%
4alzA02 3.30.1340.30 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 0.68 55.0 5.78e-01 97.4% 100.0%
4r0mA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.68 58.0 5.13e-01 93.4% 70.4%
2w3sB03 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.67 43.0 4.07e-01 77.6% 53.2%
2onfA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.67 57.0 4.76e-01 96.1% 70.1%
3gkuC02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.67 55.0 5.25e-01 92.1% 91.0%
5g5gC03 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.66 42.0 4.03e-01 76.3% 53.8%
3kxwA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.66 56.0 4.76e-01 94.7% 86.3%
2d7vB00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.66 55.0 4.48e-01 96.1% 63.4%
2rffA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.65 53.0 4.76e-01 93.4% 71.2%
4alzA01 3.30.1340.30 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 0.64 47.0 5.08e-01 96.1% 100.0%
7r7eA01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.63 54.0 4.66e-01 94.7% 88.2%
1hh2P04 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.62 49.0 5.18e-01 98.7% 98.5%
1uwvA03 2.40.50.1070 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.62 50.0 4.25e-01 93.4% 51.8%
4f7oA00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.61 42.0 3.00e-01 71.1% 46.8%
4zohA02 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.60 52.0 4.42e-01 100.0% 60.9%
4oxiA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.60 52.0 4.87e-01 100.0% 81.6%
2d27A02 3.30.300.160 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Type II secretion system, protein E, N-terminal domain 0.59 44.0 4.33e-01 100.0% 72.9%
2qubA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 51.0 3.39e-01 97.4% 45.9%
6upsA01 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.59 51.0 4.16e-01 100.0% 66.5%
6vhvA01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.59 52.0 4.91e-01 100.0% 80.6%
1ffvB02 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.59 53.0 4.28e-01 100.0% 54.5%
1lrzA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.59 49.0 4.06e-01 94.7% 53.1%
3v8hC00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.59 50.0 3.44e-01 97.4% 31.6%
1u9dA00 3.30.429.10 Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor 0.59 50.0 4.39e-01 100.0% 78.7%
1m4jA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.59 47.0 4.03e-01 92.1% 75.9%
2oo4A02 3.30.70.3310 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 45.0 4.04e-01 85.5% 82.9%
3upsA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.58 50.0 4.49e-01 97.4% 85.2%
1xe4A01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.58 47.0 3.77e-01 93.4% 45.1%
5jr6A02 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.57 48.0 3.82e-01 93.4% 51.3%
4d10F01 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.57 39.0 3.04e-01 72.4% 52.5%
2oc3A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 44.0 3.06e-01 85.5% 58.1%
2kdnA00 3.30.300.90 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like 0.57 47.0 4.32e-01 97.4% 75.9%
2d8bA01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.57 46.0 3.85e-01 92.1% 72.9%
2euiA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.57 45.0 3.80e-01 90.8% 58.6%
1no5B00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.56 48.0 4.44e-01 100.0% 95.1%
1dgjA05 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.56 37.0 3.56e-01 76.3% 55.3%
3lklA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.56 39.0 3.68e-01 72.4% 95.7%
3fvyA03 3.30.70.2600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 46.0 4.70e-01 93.4% 96.0%
2mv2A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.56 45.0 3.73e-01 92.1% 73.0%
2xf1A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.55 44.0 3.85e-01 92.1% 74.6%
5ce6A01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.54 47.0 3.76e-01 100.0% 73.8%
2gerA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.49e-01 93.4% 90.7%
1zejA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 43.0 3.48e-01 92.1% 93.3%
4yt9A01 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.54 46.0 3.12e-01 100.0% 90.5%
3mogA03 3.30.750.190 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.54 42.0 4.01e-01 89.5% 78.7%
6a8mA01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.53 46.0 3.61e-01 100.0% 71.9%
1vkpB00 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.52 44.0 2.96e-01 100.0% 92.6%
3c24A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 41.0 3.22e-01 88.2% 90.4%
1a7tA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.52 44.0 3.27e-01 100.0% 66.1%
2wtbA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 41.0 3.28e-01 92.1% 93.3%
2i5tA00 3.10.490.10 Alpha Beta › Roll › Hypothetical upf0131 protein ytfp › Gamma-glutamyl cyclotransferase-like 0.52 39.0 3.14e-01 85.5% 60.9%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 44.0 3.71e-01 100.0% 74.5%
3lx4A02 3.40.950.10 Alpha Beta › 3-Layer(aba) Sandwich › Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3 › Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3 0.51 39.0 2.90e-01 82.9% 64.1%
1tdjA01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 43.0 3.21e-01 100.0% 82.1%
1i36A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 42.0 3.40e-01 96.1% 89.3%
ECOD (85)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4153568 327.17.1.3 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_M 0.87 81.0 7.01e-01 100.0% 87.3%
4100012 327.13.1.5 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › SpoIIIAH 0.76 64.0 5.46e-01 100.0% 58.5%
3964178 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.74 60.0 5.01e-01 89.5% 68.1%
2117172 327.12.1.1 a+b two layers › Alpha-lytic protease prodomain-like › UbiD C-terminal domain-like › UbiD C-terminal domain-like › UbiD_C 0.73 63.0 4.84e-01 96.1% 79.7%
1170594 885.1.1.1 a+b complex topology › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › NusA_N 0.70 51.0 4.72e-01 76.3% 61.1%
4944088 231.1.1.2 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Molybdenum cofactor-binding domain › MoCoBD_2 0.70 63.0 4.18e-01 100.0% 76.3%
4148490 327.10.1.2 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA 0.69 57.0 4.92e-01 92.1% 75.8%
4565003 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.68 58.0 4.94e-01 96.1% 69.2%
4957577 327.20.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Baseplate structural protein gp6 C-terminal domain I › Baseplate structural protein gp6 C-terminal domain I 0.68 52.0 5.57e-01 90.8% 96.9%
4934708 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.68 60.0 5.70e-01 100.0% 91.1%
4940572 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.68 59.0 4.60e-01 100.0% 71.4%
3598535 324.1.1.0 a+b two layers › OsmC-like › OsmC-like › OsmC-like 0.67 54.0 5.19e-01 89.5% 90.0%
3861384 327.2.1.1 a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA 0.67 59.0 5.84e-01 100.0% 100.0%
3709022 327.4.1.0 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain 0.66 56.0 5.38e-01 96.1% 93.3%
4339794 327.10.1.2 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA 0.66 55.0 4.74e-01 92.1% 74.2%
3279248 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.66 59.0 5.23e-01 100.0% 72.7%
4216562 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.65 55.0 5.24e-01 94.7% 77.8%
4949378 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.65 57.0 5.34e-01 100.0% 87.4%
3894542 11.1.1.978 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29952 0.65 50.0 4.80e-01 84.2% 75.6%
5028843 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.65 52.0 4.71e-01 89.5% 70.5%
3596196 327.10.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related 0.64 53.0 4.54e-01 93.4% 56.0%
3952151 327.5.1.6 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-dom_DIP2-like 0.64 54.0 4.65e-01 94.7% 83.1%
3285521 327.5.1.6 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-dom_DIP2-like 0.64 53.0 4.66e-01 94.7% 96.7%
5037775 327.1.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain 0.63 49.0 5.19e-01 98.7% 98.5%
4972546 231.1.3.1 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Neutral ceramidase large domain › Ceramidase_alk 0.63 55.0 3.57e-01 98.7% 45.3%
5024456 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.63 50.0 4.63e-01 100.0% 67.0%
3608263 327.10.1.12 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › PSP1 0.63 52.0 5.25e-01 93.4% 93.3%
4125352 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.63 53.0 4.44e-01 93.4% 70.8%
5026215 327.12.1.1 a+b two layers › Alpha-lytic protease prodomain-like › UbiD C-terminal domain-like › UbiD C-terminal domain-like › UbiD_C 0.63 51.0 4.39e-01 93.4% 93.1%
3490940 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.63 53.0 4.34e-01 93.4% 74.3%
3732732 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.62 52.0 4.50e-01 92.1% 65.3%
5003241 102.7.1.1 alpha arrays › HhH/H2TH › Baseplate wedge protein gp7 domain IV › Baseplate wedge protein gp7 domain IV › Tail_P2_I 0.62 53.0 4.61e-01 93.4% 63.5%
4991181 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.62 47.0 5.01e-01 88.2% 100.0%
3987781 327.13.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system 0.62 50.0 4.94e-01 98.7% 87.5%
3213519 316.1.1.5 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RsfS 0.62 55.0 4.60e-01 100.0% 76.9%
5028322 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.61 53.0 4.94e-01 100.0% 98.0%
4442243 327.1.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain › Pro_Al_protease 0.61 47.0 4.86e-01 100.0% 94.3%
5047895 327.5.1.10 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › PF27533 0.61 50.0 4.69e-01 93.4% 82.1%
1002454 231.1.3.1 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Neutral ceramidase large domain › Ceramidase_alk 0.61 53.0 3.25e-01 98.7% 51.2%
4018954 327.10.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related 0.61 53.0 4.65e-01 100.0% 77.4%
3056798 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.60 47.0 4.97e-01 96.1% 100.0%
4963032 244.2.1.15 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › TSCPD 0.60 43.0 3.86e-01 76.3% 88.2%
3178454 131.1.1.27 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › RTG2_C 0.60 49.0 3.64e-01 92.1% 88.1%
1487481 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.60 52.0 4.85e-01 100.0% 80.8%
4015553 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.60 51.0 4.82e-01 100.0% 77.9%
5027878 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.60 52.0 4.68e-01 100.0% 91.8%
3947813 316.1.1.46 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › SseB_C 0.60 52.0 4.81e-01 98.7% 97.0%
4977836 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.60 50.0 3.26e-01 96.1% 21.1%
5078295 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.60 51.0 4.38e-01 100.0% 76.2%
3602517 327.13.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system 0.59 47.0 4.67e-01 89.5% 86.3%
3997846 207.1.1.142 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_4, LRR_6, LRR_8 0.59 49.0 3.06e-01 97.4% 15.1%
2636487 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.59 53.0 4.86e-01 100.0% 78.8%
4033978 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.59 51.0 4.81e-01 100.0% 81.1%
4622549 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.59 50.0 4.23e-01 93.4% 70.4%
3960804 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.59 49.0 4.13e-01 96.1% 57.8%
3518649 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.58 51.0 5.10e-01 100.0% 100.0%
3372583 632.3.1.15 alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain › PF31063 0.58 47.0 3.30e-01 89.5% 27.7%
3310910 207.1.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1 0.58 43.0 3.22e-01 96.1% 29.8%
4996228 2487.1.1.0 a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" 0.58 42.0 3.66e-01 90.8% 48.0%
5009414 327.5.1.3 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 0.58 49.0 4.70e-01 97.4% 85.6%
3375024 3261.1.1.0 a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb 0.58 43.0 4.67e-01 84.2% 98.4%
3480553 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.58 48.0 3.98e-01 93.4% 75.7%
3909868 221.1.1.89 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Il2rg 0.58 41.0 3.60e-01 76.3% 62.5%
5046968 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.57 46.0 3.97e-01 94.7% 67.4%
3381186 315.1.1.8 a+b two layers › Tautomerase/MIF-like › Tautomerase/MIF › Tautomerase/MIF › DUF3783 0.57 47.0 4.04e-01 93.4% 79.2%
3558201 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.57 48.0 4.16e-01 100.0% 80.8%
4946421 2004.1.1.120 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.57 41.0 2.48e-01 81.6% 9.6%
3952449 2008.1.1.114 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143 0.56 47.0 4.22e-01 94.7% 68.2%
3287751 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.56 50.0 3.66e-01 100.0% 46.8%
3338857 246.3.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like 0.56 43.0 3.37e-01 94.7% 37.1%
4043600 327.18.1.0 a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A 0.56 43.0 4.24e-01 86.8% 91.8%
1887793 231.1.1.1 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Molybdenum cofactor-binding domain › MoCoBD_1 0.55 48.0 3.38e-01 100.0% 64.0%
420847 224.1.1.1 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF 0.55 44.0 3.90e-01 92.1% 80.8%
3631027 232.1.1.3 a+b duplicates or obligate multimers › Pentein › Pentein › Pentein › PAD 0.55 46.0 3.07e-01 100.0% 76.8%
3634678 224.1.1.1 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF 0.55 44.0 3.84e-01 93.4% 73.4%
5045446 327.18.1.0 a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A 0.54 43.0 4.06e-01 92.1% 72.6%
3287151 327.1.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain 0.54 46.0 4.11e-01 100.0% 92.2%
5028121 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.54 44.0 3.80e-01 96.1% 64.6%
1130223 2003.1.1.77 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3HCDH_RFF 0.54 42.0 3.93e-01 89.5% 74.0%
3268419 224.1.1.1 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF 0.53 43.0 3.81e-01 93.4% 79.1%
4000395 2007.1.1.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like 0.52 35.0 2.68e-01 80.3% 25.2%
3926365 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.52 44.0 2.76e-01 97.4% 27.5%
2499548 2004.1.1.53 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.51 43.0 3.84e-01 96.1% 80.4%
4951625 3261.1.1.0 a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb 0.50 43.0 4.21e-01 100.0% 90.6%
3204296 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.50 40.0 2.76e-01 93.4% 82.3%
D3 medium residues 1-82_191-217
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00438.26 best S-AdoMet_synt_N 95.2 4.20e-27 87.2% 84.9%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4le5A02 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.97 88.0 8.00e-01 93.6% 93.4%
6rk7B02 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.96 87.0 8.16e-01 93.6% 93.0%
2pn2A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.69 48.0 4.49e-01 71.6% 89.8%
1uwvA03 2.40.50.1070 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.56 40.0 3.79e-01 75.2% 64.2%
2d27A02 3.30.300.160 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Type II secretion system, protein E, N-terminal domain 0.53 34.0 3.74e-01 89.9% 82.4%
2rffA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.52 40.0 4.06e-01 84.4% 95.5%
4yt9A01 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.51 40.0 2.94e-01 84.4% 46.2%
3c7aA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 35.0 2.92e-01 70.6% 93.7%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4279781 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.97 78.0 6.98e-01 81.7% 100.0%
3662621 327.17.1.7 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N, S-AdoMet_synt_M, S-AdoMet_synt_C 0.97 95.0 6.15e-01 100.0% 68.8%
4448090 327.17.1.7 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N, S-AdoMet_synt_M, S-AdoMet_synt_C 0.97 94.0 6.07e-01 100.0% 68.6%
3599210 327.17.1.0 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase 0.97 67.0 6.73e-01 70.6% 82.7%
3292415 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.97 73.0 7.66e-01 77.1% 100.0%
3558170 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.97 69.0 6.89e-01 72.5% 84.5%
3387980 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.97 76.0 7.63e-01 80.7% 100.0%
4051119 327.17.1.5 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N+S-AdoMet_synt_M 0.97 76.0 5.54e-01 80.7% 100.0%
4402587 327.17.1.5 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N+S-AdoMet_synt_M 0.96 77.0 5.74e-01 82.6% 95.7%
4628287 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.93 65.0 6.66e-01 71.6% 91.4%
4970157 327.17.1.4 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_C 0.91 85.0 5.59e-01 96.3% 66.8%
3440248 327.17.1.5 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N+S-AdoMet_synt_M 0.79 72.0 6.15e-01 94.5% 86.3%
4928329 327.17.1.1 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N 0.76 72.0 5.10e-01 97.2% 83.5%
4243535 327.13.1.15 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › Spore_YhcN_YlaJ 0.67 45.0 5.29e-01 73.4% 100.0%
4442055 869.1.1.1 a+b complex topology › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › MCH 0.61 45.0 3.27e-01 78.0% 94.8%
5072447 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.60 43.0 4.46e-01 75.2% 97.1%
4979235 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.60 43.0 4.07e-01 76.1% 85.9%
5047895 327.5.1.10 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › PF27533 0.59 45.0 4.78e-01 79.8% 97.9%
4947751 869.1.1.1 a+b complex topology › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › MCH 0.58 43.0 3.18e-01 78.9% 95.2%
2698946 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.57 44.0 4.29e-01 89.0% 74.8%
3588726 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.57 39.0 4.26e-01 90.8% 86.7%
5078110 327.5.1.10 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › PF27533 0.56 43.0 4.47e-01 93.6% 88.0%
5031901 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.54 45.0 4.25e-01 89.0% 80.0%
5033939 327.5.1.10 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › PF27533 0.53 47.0 4.14e-01 100.0% 95.2%
196923 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.52 40.0 4.06e-01 84.4% 95.5%
5054483 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.51 41.0 4.37e-01 93.6% 100.0%
4217250 2003.1.5.53 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.50 42.0 3.00e-01 93.6% 97.2%
None 0.50 42.0 2.95e-01 92.7% 92.7%