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IMGVR_UViG_3300024264_003363-3300024264-Ga0233444_100248902
Arc-VirIMGVR_UViG_3300024264_003363-3300024264-Ga0233444_100248902
Identity
- Kingdom:
- archaea
Quality
83.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 646-804
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fhnA03 | 1.10.357.100 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C | 0.70 | 57.0 | 5.56e-01 | 86.2% | 98.9% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.69 | 50.0 | 5.03e-01 | 74.2% | 96.9% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 51.0 | 4.77e-01 | 76.7% | 93.2% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.65 | 28.0 | 3.78e-01 | 78.0% | 77.5% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.64 | 52.0 | 5.13e-01 | 86.8% | 91.9% |
| 5xtck00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 32.0 | 4.02e-01 | 71.1% | 77.3% |
| 3zheB02 | 1.20.190.60 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › | 0.63 | 50.0 | 4.78e-01 | 95.0% | 72.4% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.63 | 49.0 | 4.51e-01 | 81.1% | 82.3% |
| 2v7kA01 | 1.20.58.1320 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 38.0 | 4.35e-01 | 75.5% | 82.6% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.62 | 50.0 | 4.48e-01 | 86.8% | 83.4% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 42.0 | 4.41e-01 | 73.0% | 77.5% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 40.0 | 4.56e-01 | 70.4% | 92.0% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.61 | 37.0 | 3.96e-01 | 89.3% | 68.3% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.60 | 51.0 | 4.20e-01 | 98.7% | 50.2% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 40.0 | 4.46e-01 | 70.4% | 87.0% |
| 4wr4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 38.0 | 4.44e-01 | 78.6% | 94.3% |
| 7qx4A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.58 | 53.0 | 4.66e-01 | 98.7% | 67.9% |
| 1txuA02 | 1.20.1050.80 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain | 0.58 | 40.0 | 4.01e-01 | 80.5% | 68.1% |
| 6ljaA01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.58 | 47.0 | 3.61e-01 | 96.2% | 37.8% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 40.0 | 4.24e-01 | 91.2% | 78.5% |
| 4in3B00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 44.0 | 3.03e-01 | 98.1% | 21.9% |
| 8g0lB01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 45.0 | 3.40e-01 | 100.0% | 35.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.55 | 34.0 | 3.89e-01 | 89.3% | 84.2% |
| 4rg9B01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 34.0 | 3.40e-01 | 94.3% | 58.1% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.53 | 38.0 | 3.85e-01 | 98.7% | 74.0% |
| 2gfnA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 45.0 | 4.30e-01 | 93.1% | 93.8% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.53 | 34.0 | 3.46e-01 | 91.2% | 64.7% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 45.0 | 3.62e-01 | 91.2% | 73.7% |
| 7zcvA02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 46.0 | 4.15e-01 | 99.4% | 70.0% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.52 | 41.0 | 3.41e-01 | 83.0% | 94.8% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 46.0 | 4.47e-01 | 95.6% | 96.0% |
| 1k74D00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.52 | 42.0 | 3.62e-01 | 89.3% | 86.0% |
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 43.0 | 4.39e-01 | 94.3% | 91.1% |
| 4nleA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.52 | 41.0 | 3.50e-01 | 83.6% | 78.9% |
| 3bruB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 45.0 | 4.25e-01 | 94.3% | 95.2% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.51 | 37.0 | 3.62e-01 | 73.6% | 74.4% |
| 7drjB01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.51 | 47.0 | 4.46e-01 | 98.7% | 99.5% |
| 2xs1A01 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.51 | 45.0 | 3.52e-01 | 98.1% | 62.5% |
| 8g59R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 41.0 | 3.48e-01 | 86.2% | 74.7% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 42.0 | 4.31e-01 | 88.1% | 100.0% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 41.0 | 4.29e-01 | 87.4% | 95.9% |
| 4hzuS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.50 | 39.0 | 3.89e-01 | 87.4% | 78.7% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.50 | 36.0 | 3.95e-01 | 98.1% | 91.4% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3495045 | 109.4.1.373 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m | 0.77 | 66.0 | 5.27e-01 | 90.6% | 64.0% |
| 5039560 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 61.0 | 5.73e-01 | 98.1% | 73.2% |
| 3742108 | 109.4.1.1340 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m, COG4_C, COG4_N | 0.73 | 63.0 | 4.16e-01 | 93.1% | 33.6% |
| 3648097 | 109.4.1.429 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HDS | 0.69 | 58.0 | 5.39e-01 | 100.0% | 71.0% |
| 3175456 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.69 | 62.0 | 4.05e-01 | 98.7% | 27.9% |
| 3684581 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.68 | 43.0 | 3.95e-01 | 98.7% | 48.3% |
| 3610795 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 58.0 | 4.61e-01 | 94.3% | 81.2% |
| 3834159 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.67 | 45.0 | 4.38e-01 | 97.5% | 61.1% |
| 3306714 | 109.4.1.1272 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif | 0.66 | 42.0 | 3.18e-01 | 96.9% | 27.2% |
| 3740232 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 52.0 | 5.51e-01 | 90.6% | 94.3% |
| 3742992 | 109.4.1.228 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C | 0.66 | 57.0 | 5.13e-01 | 93.7% | 68.5% |
| 3515232 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 60.0 | 4.67e-01 | 99.4% | 76.4% |
| 3427191 | 109.4.1.1254 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif | 0.65 | 41.0 | 3.97e-01 | 96.9% | 55.6% |
| 3667878 | 109.4.1.1724 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SPG48, TPR_AP5Z1_C | 0.64 | 58.0 | 4.23e-01 | 100.0% | 35.1% |
| 3710394 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 59.0 | 5.06e-01 | 100.0% | 67.8% |
| 3893725 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 58.0 | 4.17e-01 | 98.7% | 57.4% |
| 4030167 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.63 | 51.0 | 5.04e-01 | 87.4% | 82.7% |
| 157647 | 133.2.1.1 ↗ | alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C | 0.63 | 49.0 | 4.43e-01 | 81.1% | 78.4% |
| 3594703 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 56.0 | 3.80e-01 | 99.4% | 28.4% |
| 4001569 | 109.4.1.1493 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C, ZW10_C2 | 0.62 | 54.0 | 3.66e-01 | 94.3% | 41.9% |
| 3270005 | 5000.4.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N | 0.61 | 50.0 | 4.25e-01 | 86.8% | 62.7% |
| 3790051 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.61 | 42.0 | 4.08e-01 | 88.1% | 62.2% |
| 3704705 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 52.0 | 4.07e-01 | 96.2% | 56.9% |
| 3751117 | 109.4.1.937 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_EDRF1 | 0.59 | 51.0 | 5.03e-01 | 96.2% | 94.9% |
| 3710472 | 604.3.1.11 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 | 0.59 | 49.0 | 4.16e-01 | 87.4% | 96.4% |
| 3286124 | 109.4.1.679 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3151 | 0.59 | 43.0 | 4.57e-01 | 98.7% | 88.9% |
| 4057126 | 109.4.1.1290 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_19 | 0.58 | 40.0 | 3.22e-01 | 86.8% | 34.8% |
| 3271775 | 109.4.1.32 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G | 0.58 | 52.0 | 4.27e-01 | 100.0% | 57.0% |
| 3935428 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 41.0 | 3.98e-01 | 96.9% | 67.8% |
| 3176473 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.55 | 37.0 | 4.05e-01 | 74.2% | 83.1% |
| 3794245 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.55 | 43.0 | 3.93e-01 | 83.6% | 83.6% |
| 5065759 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.55 | 40.0 | 4.48e-01 | 76.1% | 96.8% |
| 3520835 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 40.0 | 3.72e-01 | 98.1% | 60.0% |
| 3829044 | 109.4.1.1272 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif | 0.54 | 42.0 | 3.42e-01 | 99.4% | 44.5% |
| 3400367 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 43.0 | 4.44e-01 | 93.1% | 90.7% |
| 3268234 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 43.0 | 4.52e-01 | 89.9% | 95.2% |
| 3223927 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 42.0 | 3.24e-01 | 98.1% | 36.4% |
| 4946446 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.53 | 38.0 | 3.79e-01 | 74.8% | 70.3% |
| 3899807 | 109.4.1.1568 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_8 | 0.52 | 44.0 | 4.11e-01 | 94.3% | 73.8% |
| 3840819 | 109.4.1.2045 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_6 | 0.52 | 43.0 | 4.04e-01 | 92.5% | 72.8% |
| 3480125 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.52 | 44.0 | 3.36e-01 | 93.1% | 65.6% |
| 3557559 | 109.4.1.5 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 | 0.51 | 43.0 | 3.99e-01 | 92.5% | 71.0% |
| 3801203 | 109.4.1.2247 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, TPR_8, TPR_19 | 0.51 | 45.0 | 2.98e-01 | 96.9% | 40.6% |
D2
medium
residues 75-248
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 48.0 | 4.71e-01 | 100.0% | 66.1% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.68 | 36.0 | 4.40e-01 | 74.7% | 78.6% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 37.0 | 4.17e-01 | 71.8% | 70.3% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 38.0 | 3.99e-01 | 75.3% | 65.4% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 36.0 | 4.09e-01 | 71.3% | 75.0% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 39.0 | 4.49e-01 | 72.4% | 86.0% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.61 | 40.0 | 4.51e-01 | 71.3% | 89.0% |
| 3e6sA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 41.0 | 4.26e-01 | 86.8% | 75.5% |
| 4in3B00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 42.0 | 2.92e-01 | 100.0% | 21.6% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 37.0 | 4.46e-01 | 71.8% | 93.2% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.58 | 47.0 | 4.77e-01 | 98.9% | 85.5% |
| 1jgcA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 38.0 | 4.02e-01 | 86.8% | 73.1% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 42.0 | 4.55e-01 | 95.4% | 91.0% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 40.0 | 3.25e-01 | 72.4% | 83.2% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 37.0 | 4.13e-01 | 85.6% | 84.7% |
| 4doyA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 38.0 | 3.77e-01 | 72.4% | 66.1% |
| 2f2bA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.55 | 39.0 | 3.49e-01 | 72.4% | 75.9% |
| 2j1oA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 41.0 | 3.68e-01 | 90.8% | 53.3% |
| 1ki1B01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 47.0 | 4.51e-01 | 93.7% | 89.9% |
| 4p3gD00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.54 | 47.0 | 4.56e-01 | 94.8% | 91.8% |
| 3lk5A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 45.0 | 3.65e-01 | 90.2% | 58.3% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 42.0 | 3.65e-01 | 83.3% | 80.4% |
| 1eqfA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 33.0 | 3.85e-01 | 84.5% | 86.4% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.53 | 34.0 | 3.92e-01 | 96.0% | 86.7% |
| 2lo6A00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 38.0 | 4.01e-01 | 100.0% | 82.5% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.52 | 38.0 | 3.91e-01 | 74.1% | 95.7% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 35.0 | 3.71e-01 | 86.8% | 75.8% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 43.0 | 4.07e-01 | 89.1% | 95.3% |
| 7zcvA02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 40.0 | 3.81e-01 | 100.0% | 67.6% |
| 3sghA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 46.0 | 3.35e-01 | 97.1% | 97.5% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 41.0 | 3.47e-01 | 83.3% | 87.8% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 33.0 | 3.82e-01 | 93.7% | 92.3% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 39.0 | 4.08e-01 | 90.8% | 87.1% |
| 3jysA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 39.0 | 3.61e-01 | 78.7% | 97.7% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 43.0 | 4.54e-01 | 100.0% | 100.0% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.51 | 36.0 | 3.85e-01 | 85.1% | 81.2% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 37.0 | 4.04e-01 | 93.1% | 93.5% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 36.0 | 3.52e-01 | 73.0% | 87.8% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 37.0 | 4.00e-01 | 90.8% | 89.3% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.50 | 40.0 | 3.92e-01 | 93.7% | 78.0% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3817153 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.67 | 36.0 | 4.53e-01 | 70.7% | 85.7% |
| 3874130 | 133.1.1.5 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › DH_Alsin | 0.65 | 52.0 | 4.90e-01 | 83.9% | 83.3% |
| 3748768 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 49.0 | 3.79e-01 | 82.8% | 45.6% |
| 4968636 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.61 | 44.0 | 4.48e-01 | 86.8% | 74.1% |
| 1171944 | 633.6.1.4 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_2 | 0.61 | 37.0 | 3.80e-01 | 73.0% | 59.6% |
| 3615588 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.61 | 49.0 | 3.58e-01 | 83.9% | 38.7% |
| 3405367 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 43.0 | 4.69e-01 | 83.9% | 86.0% |
| 3400585 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.60 | 45.0 | 3.92e-01 | 76.4% | 87.7% |
| None | — | 0.59 | 45.0 | 3.13e-01 | 78.7% | 46.0% | |
| 3932332 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.59 | 45.0 | 3.66e-01 | 77.6% | 86.7% |
| 3932724 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 44.0 | 3.79e-01 | 76.4% | 52.2% |
| 3235109 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.59 | 45.0 | 4.34e-01 | 79.9% | 71.0% |
| 3722363 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.58 | 45.0 | 4.67e-01 | 79.9% | 88.1% |
| 4054418 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.58 | 44.0 | 3.93e-01 | 79.9% | 76.0% |
| 3693071 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.57 | 52.0 | 3.76e-01 | 100.0% | 42.4% |
| 4681450 | 109.4.1.451 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 | 0.57 | 51.0 | 3.48e-01 | 98.3% | 46.6% |
| 3786684 | 109.4.1.269 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3 | 0.56 | 39.0 | 3.84e-01 | 98.9% | 64.2% |
| 3445853 | 601.1.1.56 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF7798 | 0.56 | 48.0 | 4.91e-01 | 92.5% | 98.2% |
| 3623555 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.56 | 44.0 | 4.67e-01 | 86.8% | 93.5% |
| 3940488 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 50.0 | 3.97e-01 | 98.3% | 69.9% |
| 3615590 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 38.0 | 4.51e-01 | 90.2% | 100.0% |
| 3887418 | 633.21.1.46 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › TMEM125 | 0.55 | 42.0 | 4.50e-01 | 86.8% | 94.0% |
| 4000583 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.55 | 41.0 | 3.88e-01 | 75.9% | 65.5% |
| 3396975 | 603.2.1.12 ↗ | alpha bundles › STAT-like › STAT › STAT › 7tm_7 | 0.55 | 46.0 | 3.55e-01 | 90.2% | 59.8% |
| 3627937 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.55 | 44.0 | 4.16e-01 | 85.1% | 76.7% |
| 4880481 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.54 | 36.0 | 3.83e-01 | 87.4% | 74.7% |
| 3610444 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 46.0 | 4.08e-01 | 90.2% | 74.4% |
| 3626646 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.54 | 45.0 | 4.34e-01 | 86.8% | 82.6% |
| 3649030 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.54 | 43.0 | 3.78e-01 | 84.5% | 75.6% |
| 5047181 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 42.0 | 3.87e-01 | 82.2% | 80.9% |
| 3593307 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 49.0 | 4.27e-01 | 99.4% | 90.8% |
| 3617776 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.53 | 42.0 | 3.55e-01 | 82.8% | 84.1% |
| 4026662 | 4207.1.2.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region | 0.53 | 41.0 | 4.44e-01 | 83.9% | 99.3% |
| 5018946 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.53 | 39.0 | 3.86e-01 | 81.0% | 71.0% |
| 3467440 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 42.0 | 3.91e-01 | 99.4% | 65.3% |
| 3691242 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.53 | 42.0 | 4.00e-01 | 82.8% | 97.6% |
| 3240737 | 5082.1.1.0 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like | 0.53 | 45.0 | 4.14e-01 | 89.7% | 95.9% |
| 3599655 | 109.4.1.451 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 | 0.52 | 46.0 | 3.10e-01 | 96.0% | 38.4% |
| 3992024 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.52 | 42.0 | 3.40e-01 | 86.2% | 49.1% |
| 5002084 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 41.0 | 3.66e-01 | 82.2% | 86.1% |
| 3616727 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.52 | 43.0 | 4.03e-01 | 87.9% | 87.6% |
| 4160177 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 47.0 | 3.33e-01 | 100.0% | 47.3% |
| 4652128 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.51 | 41.0 | 3.88e-01 | 84.5% | 92.9% |
| 4025485 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.51 | 39.0 | 4.04e-01 | 93.1% | 82.9% |
| 3510338 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.50 | 44.0 | 3.61e-01 | 95.4% | 71.7% |
| 5035877 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.50 | 41.0 | 3.82e-01 | 85.6% | 92.6% |
| 5079216 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.50 | 38.0 | 4.08e-01 | 85.1% | 92.0% |
| 3722086 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 44.0 | 3.33e-01 | 94.3% | 77.8% |
| 4323952 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.50 | 40.0 | 4.13e-01 | 92.0% | 87.2% |
| 4257548 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.50 | 44.0 | 3.86e-01 | 94.8% | 80.4% |
| 3973748 | 1075.5.1.12 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ, Polysacc_synt_3 | 0.50 | 45.0 | 3.98e-01 | 97.7% | 78.0% |
| 4859202 | 1076.1.1.2 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Aph-1 | 0.50 | 39.0 | 3.56e-01 | 81.0% | 80.5% |
D3
medium
residues 249-343
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 62.0 | 5.79e-01 | 86.3% | 95.7% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 58.0 | 6.37e-01 | 96.8% | 98.7% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 58.0 | 5.74e-01 | 81.1% | 88.1% |
| 2o8pA00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.75 | 61.0 | 4.64e-01 | 88.4% | 52.5% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.75 | 64.0 | 5.00e-01 | 92.6% | 85.6% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 51.0 | 5.66e-01 | 96.8% | 98.6% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.70 | 56.0 | 5.12e-01 | 89.5% | 65.1% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 55.0 | 5.13e-01 | 91.6% | 67.2% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 56.0 | 5.41e-01 | 88.4% | 91.5% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.69 | 60.0 | 5.07e-01 | 97.9% | 96.9% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.68 | 59.0 | 5.63e-01 | 93.7% | 86.4% |
| 1w9cA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.68 | 56.0 | 3.89e-01 | 100.0% | 27.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 55.0 | 5.30e-01 | 89.5% | 94.4% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.67 | 59.0 | 5.63e-01 | 93.7% | 88.9% |
| 1hu3A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 50.0 | 3.92e-01 | 100.0% | 36.8% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 46.0 | 4.53e-01 | 73.7% | 95.1% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 56.0 | 5.17e-01 | 94.7% | 85.2% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 57.0 | 4.91e-01 | 100.0% | 70.1% |
| 2rekA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 57.0 | 4.72e-01 | 100.0% | 89.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 52.0 | 5.13e-01 | 90.5% | 96.1% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.61 | 46.0 | 4.56e-01 | 94.7% | 76.5% |
| 3cqcB01 | 1.20.58.1380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 51.0 | 5.23e-01 | 100.0% | 96.7% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 49.0 | 4.95e-01 | 88.4% | 95.7% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 52.0 | 5.26e-01 | 94.7% | 100.0% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 47.0 | 4.04e-01 | 85.3% | 92.9% |
| 3m6jA01 | 1.20.1260.40 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.59 | 52.0 | 4.82e-01 | 94.7% | 99.1% |
| 3bvoB01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.59 | 47.0 | 4.69e-01 | 94.7% | 84.7% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 49.0 | 4.44e-01 | 93.7% | 97.8% |
| 1udyA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 50.0 | 4.66e-01 | 94.7% | 79.2% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.58 | 47.0 | 4.50e-01 | 90.5% | 75.7% |
| 2jifA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 49.0 | 4.63e-01 | 94.7% | 78.8% |
| 3pasA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 49.0 | 4.02e-01 | 97.9% | 88.4% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.57 | 49.0 | 4.28e-01 | 98.9% | 84.0% |
| 4aciA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 50.0 | 4.11e-01 | 98.9% | 92.6% |
| 2or0B01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 47.0 | 4.35e-01 | 94.7% | 71.8% |
| 2fgyA01 | 1.20.120.1310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Carboxysome Shell Carbonic Anhydrase, N-terminal helical domain | 0.56 | 36.0 | 3.50e-01 | 89.5% | 57.9% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.54 | 41.0 | 4.00e-01 | 86.3% | 73.1% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 44.0 | 4.12e-01 | 94.7% | 73.5% |
| 7vkcA01 | 1.10.1070.20 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › | 0.54 | 47.0 | 3.98e-01 | 100.0% | 86.7% |
| 2gfpA00 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.53 | 45.0 | 3.06e-01 | 94.7% | 26.9% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 42.0 | 3.87e-01 | 96.8% | 66.4% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.21e-01 | 88.4% | 86.7% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4062922 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.79 | 57.0 | 5.06e-01 | 83.2% | 53.3% |
| 3584478 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.75 | 58.0 | 5.97e-01 | 90.5% | 86.7% |
| 3498448 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.75 | 59.0 | 6.36e-01 | 86.3% | 100.0% |
| 3238213 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 60.0 | 5.72e-01 | 86.3% | 98.2% |
| 3999485 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 61.0 | 5.23e-01 | 91.6% | 76.4% |
| 3610785 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 59.0 | 3.79e-01 | 100.0% | 19.5% |
| 3622515 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 52.0 | 5.43e-01 | 97.9% | 87.1% |
| 3791916 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.70 | 50.0 | 5.52e-01 | 83.2% | 94.7% |
| 3703277 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.70 | 49.0 | 5.52e-01 | 93.7% | 100.0% |
| 3943720 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 59.0 | 5.15e-01 | 93.7% | 62.1% |
| 3631582 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.69 | 58.0 | 5.72e-01 | 90.5% | 94.0% |
| 4387552 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.68 | 55.0 | 5.80e-01 | 93.7% | 100.0% |
| 3401856 | 601.34.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › F-actin binding domain of Abl › F-actin binding domain of Abl › F_actin_bind | 0.67 | 53.0 | 5.03e-01 | 95.8% | 71.8% |
| 3883666 | 603.1.1.8 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Spectrin_2 | 0.67 | 52.0 | 5.63e-01 | 92.6% | 98.8% |
| 3809587 | 109.4.1.1742 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_CPL3 | 0.67 | 55.0 | 4.93e-01 | 100.0% | 63.7% |
| 3199446 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 48.0 | 4.71e-01 | 96.8% | 70.0% |
| 3478235 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.65 | 55.0 | 5.05e-01 | 94.7% | 80.5% |
| 4223248 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.65 | 52.0 | 5.05e-01 | 89.5% | 85.5% |
| 4009765 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 55.0 | 3.86e-01 | 96.8% | 93.4% |
| 3613133 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.62 | 47.0 | 4.91e-01 | 96.8% | 89.4% |
| 3396796 | 601.1.1.43 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A | 0.62 | 54.0 | 4.97e-01 | 96.8% | 74.2% |
| 3898384 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 52.0 | 4.71e-01 | 92.6% | 68.5% |
| 5005724 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.60 | 47.0 | 3.52e-01 | 83.2% | 36.6% |
| 3287820 | 4033.1.1.1 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N | 0.56 | 45.0 | 4.46e-01 | 94.7% | 84.0% |
| 4004423 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.56 | 46.0 | 3.28e-01 | 91.6% | 43.8% |
| 3977409 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.56 | 40.0 | 3.62e-01 | 75.8% | 91.1% |
| 3838664 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 43.0 | 3.56e-01 | 84.2% | 83.8% |
| 4486707 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.52 | 42.0 | 4.39e-01 | 89.5% | 95.3% |
| 4826576 | 150.1.1.5 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF305 | 0.51 | 39.0 | 4.15e-01 | 92.6% | 92.9% |
D4
medium
residues 344-504
Domain cluster:
rep: IMGVR_UViG_3300028844_008151-3300028844-Ga0309838_10668421__D346-505