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IMGVR_UViG_3300024515_000567-3300024515-Ga0255183_10039807
Arc-VirIMGVR_UViG_3300024515_000567-3300024515-Ga0255183_10039807
Identity
- Kingdom:
- archaea
Quality
96.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-60
Domain cluster:
representative
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pwuA04 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.79 | 71.0 | 4.76e-01 | 100.0% | 40.3% |
| 3dteA01 | 1.10.10.2910 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.75 | 62.0 | 5.00e-01 | 100.0% | 47.0% |
| 3lmcA00 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.71 | 61.0 | 4.31e-01 | 96.7% | 99.0% |
| 1ii2B01 | 3.40.449.10 | Alpha Beta › 3-Layer(aba) Sandwich › Phosphoenolpyruvate Carboxykinase; domain 1 › Phosphoenolpyruvate Carboxykinase, domain 1 | 0.68 | 58.0 | 4.21e-01 | 100.0% | 51.7% |
| 6jebA01 | 3.30.379.10 | Alpha Beta › 2-Layer Sandwich › Chitobiase; domain 2 › Chitobiase/beta-hexosaminidase domain 2-like | 0.68 | 54.0 | 5.03e-01 | 98.3% | 69.3% |
| 2ab0A00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.67 | 54.0 | 3.81e-01 | 91.7% | 55.4% |
| 4jixB00 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.65 | 58.0 | 4.82e-01 | 100.0% | 58.7% |
| 1eb6A00 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.65 | 56.0 | 4.05e-01 | 100.0% | 38.4% |
| 2rghA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.63 | 54.0 | 3.62e-01 | 100.0% | 84.3% |
| 6j7xA01 | 1.25.40.120 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase | 0.62 | 48.0 | 3.11e-01 | 85.0% | 24.0% |
| 4yshA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.62 | 53.0 | 3.62e-01 | 100.0% | 90.6% |
| 3p9dD02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.61 | 48.0 | 4.12e-01 | 100.0% | 52.4% |
| 3wz2B00 | 3.40.50.10900 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit | 0.61 | 50.0 | 3.46e-01 | 95.0% | 40.4% |
| 4jiuA00 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.60 | 52.0 | 4.42e-01 | 100.0% | 57.1% |
| 6ks6Z02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.60 | 48.0 | 4.05e-01 | 100.0% | 50.5% |
| 3hbvP01 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.59 | 50.0 | 3.92e-01 | 98.3% | 87.0% |
| 3aq1B02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.58 | 46.0 | 3.88e-01 | 100.0% | 49.1% |
| 7lhsB01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.58 | 39.0 | 2.74e-01 | 100.0% | 21.1% |
| 1f6bB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 45.0 | 3.31e-01 | 88.3% | 35.0% |
| 4p02B05 | 1.20.5.4520 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 38.0 | 3.25e-01 | 96.7% | 41.8% |
| 4fcaA02 | 3.40.390.80 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Peptidase M60, enhancin-like domain 2 | 0.57 | 46.0 | 3.59e-01 | 90.0% | 40.0% |
| 1kkmB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 47.0 | 3.52e-01 | 100.0% | 35.6% |
| 1xweA01 | 2.40.50.120 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.56 | 38.0 | 2.99e-01 | 71.7% | 99.3% |
| 2fgyA03 | 3.30.1330.140 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Carboxysome Shell Carbonic Anhydrase, C-terminal domain | 0.56 | 47.0 | 3.82e-01 | 95.0% | 74.4% |
| 1nh8A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 41.0 | 3.37e-01 | 78.3% | 99.1% |
| 4x9mA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.55 | 45.0 | 3.21e-01 | 100.0% | 91.1% |
| 4paaA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.55 | 45.0 | 3.12e-01 | 100.0% | 81.2% |
| 6ks6B02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.55 | 46.0 | 3.79e-01 | 100.0% | 59.8% |
| 4ku4A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 44.0 | 3.33e-01 | 95.0% | 57.3% |
| 6ks6G02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.55 | 46.0 | 3.95e-01 | 100.0% | 56.7% |
| 7eyoA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.54 | 44.0 | 2.86e-01 | 100.0% | 97.7% |
| 3dmyA02 | 3.40.50.261 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains | 0.54 | 45.0 | 3.58e-01 | 100.0% | 95.0% |
| 2kx7A00 | 3.40.50.11620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase RcsD, RcsD-ABL domain | 0.54 | 44.0 | 3.76e-01 | 98.3% | 57.7% |
| 4ac9C01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 45.0 | 3.28e-01 | 98.3% | 92.3% |
| 3b0xA03 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.53 | 40.0 | 3.45e-01 | 85.0% | 98.1% |
| 3icfB00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.53 | 42.0 | 2.75e-01 | 93.3% | 22.6% |
| 1fjmB00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.52 | 41.0 | 2.74e-01 | 95.0% | 22.5% |
| 3pe5A00 | 3.40.630.190 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein | 0.52 | 43.0 | 2.89e-01 | 100.0% | 45.8% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4975131 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.78 | 69.0 | 4.99e-01 | 100.0% | 47.9% |
| 5059890 | 2498.1.1.43 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin_3 | 0.73 | 61.0 | 4.39e-01 | 93.3% | 37.7% |
| None | — | 0.73 | 57.0 | 3.83e-01 | 100.0% | 22.6% | |
| 3644314 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.72 | 65.0 | 4.93e-01 | 100.0% | 48.1% |
| 3962296 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.72 | 57.0 | 3.84e-01 | 100.0% | 23.0% |
| 3954373 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.72 | 57.0 | 3.64e-01 | 100.0% | 18.0% |
| 5024540 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.71 | 61.0 | 4.51e-01 | 100.0% | 38.6% |
| 4113427 | 7541.1.1.1 ↗ | a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth | 0.70 | 59.0 | 4.28e-01 | 98.3% | 96.7% |
| 3596583 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.69 | 58.0 | 3.53e-01 | 98.3% | 39.8% |
| 3877262 | 2498.1.1.62 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 | 0.69 | 62.0 | 4.87e-01 | 100.0% | 76.0% |
| 3983196 | 2498.1.1.57 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › LPD1 | 0.69 | 62.0 | 4.12e-01 | 100.0% | 28.9% |
| 3283155 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.68 | 59.0 | 3.64e-01 | 100.0% | 95.1% |
| 5054258 | 2498.1.1.17 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like | 0.68 | 52.0 | 4.06e-01 | 100.0% | 36.6% |
| 3954991 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.67 | 60.0 | 4.13e-01 | 100.0% | 37.9% |
| 4200435 | 7541.1.1.1 ↗ | a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth | 0.67 | 56.0 | 4.10e-01 | 98.3% | 94.4% |
| 3589965 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.66 | 53.0 | 4.13e-01 | 100.0% | 40.0% |
| 4458442 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.66 | 59.0 | 4.80e-01 | 100.0% | 56.4% |
| 5053447 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.65 | 57.0 | 4.57e-01 | 100.0% | 56.8% |
| 3610113 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.65 | 46.0 | 2.76e-01 | 75.0% | 14.4% |
| 1030677 | 2498.1.1.17 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like | 0.64 | 57.0 | 4.64e-01 | 100.0% | 54.5% |
| 5009787 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.64 | 57.0 | 4.14e-01 | 100.0% | 75.2% |
| 2319457 | 2011.1.1.0 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases | 0.63 | 51.0 | 3.16e-01 | 96.7% | 19.9% |
| 3658440 | 386.1.1.26 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2_6 | 0.62 | 38.0 | 3.99e-01 | 90.0% | 67.3% |
| 4983333 | 7541.1.1.1 ↗ | a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth | 0.62 | 52.0 | 4.05e-01 | 100.0% | 96.0% |
| 4208967 | 2011.2.1.3 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro | 0.62 | 53.0 | 3.80e-01 | 100.0% | 92.1% |
| 3574190 | 2498.1.1.4 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin | 0.62 | 53.0 | 3.90e-01 | 100.0% | 35.8% |
| 3966381 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.60 | 49.0 | 3.10e-01 | 98.3% | 43.1% |
| 4974758 | 2008.1.1.51 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC | 0.60 | 49.0 | 3.66e-01 | 91.7% | 54.8% |
| 4951958 | 7584.1.1.11 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › PF27533 | 0.60 | 47.0 | 2.86e-01 | 90.0% | 12.7% |
| 3176188 | 109.4.1.3157 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29173, PF29174, PF29177 | 0.59 | 43.0 | 2.65e-01 | 76.7% | 25.1% |
| 4951965 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.58 | 46.0 | 2.91e-01 | 90.0% | 16.2% |
| 3253572 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.57 | 48.0 | 4.20e-01 | 100.0% | 64.0% |
| 3264996 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.57 | 45.0 | 3.73e-01 | 86.7% | 64.5% |
| 5028287 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.57 | 43.0 | 3.11e-01 | 95.0% | 26.0% |
| 4296144 | 2004.1.2.3 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C | 0.57 | 48.0 | 3.61e-01 | 100.0% | 39.4% |
| 5054573 | 7529.1.1.0 ↗ | a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like | 0.57 | 45.0 | 3.63e-01 | 91.7% | 83.1% |
| 4366304 | 2004.1.2.3 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C | 0.56 | 47.0 | 3.61e-01 | 100.0% | 40.6% |
| 3714820 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.55 | 47.0 | 3.62e-01 | 100.0% | 40.7% |
| 3813073 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.55 | 47.0 | 3.30e-01 | 95.0% | 53.7% |
| 327373 | 2004.1.2.3 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C | 0.55 | 46.0 | 3.40e-01 | 100.0% | 35.4% |
| 3822215 | 2498.1.1.36 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › WLM | 0.54 | 45.0 | 3.64e-01 | 100.0% | 86.7% |
| 3936168 | 2484.1.1.104 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 | 0.54 | 40.0 | 3.05e-01 | 98.3% | 33.6% |
| 4929424 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.54 | 46.0 | 4.00e-01 | 100.0% | 63.0% |
| 3886649 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.53 | 47.0 | 3.32e-01 | 100.0% | 74.7% |
| 4967919 | 7512.1.1.31 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 | 0.53 | 46.0 | 3.46e-01 | 98.3% | 40.0% |
| 4260427 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.53 | 43.0 | 2.76e-01 | 95.0% | 17.4% |
| 5000117 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.53 | 45.0 | 3.18e-01 | 98.3% | 56.1% |
| 3993461 | 261.1.1.1 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT | 0.53 | 45.0 | 2.80e-01 | 100.0% | 19.5% |
| 4021842 | 109.4.1.1553 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28151 | 0.52 | 45.0 | 2.51e-01 | 100.0% | 14.8% |
| 5027975 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.52 | 43.0 | 3.85e-01 | 100.0% | 72.6% |
| 3964976 | 4334.1.1.1 ↗ | beta complex topology › Inserted beta sandwich domain in Dac-like proteins › Inserted beta sandwich domain in Dac-like proteins › Inserted beta sandwich domain in Dac-like proteins › Peptidase_S13 | 0.52 | 41.0 | 3.83e-01 | 100.0% | 68.8% |
| 4978284 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.52 | 44.0 | 3.58e-01 | 96.7% | 75.8% |
| 5068595 | 306.4.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › YggU-like › YggU-like › DUF167 | 0.51 | 44.0 | 3.75e-01 | 98.3% | 97.0% |
| 4950090 | 306.4.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › YggU-like › YggU-like › DUF167 | 0.51 | 42.0 | 3.65e-01 | 98.3% | 92.0% |
| 4268083 | 7581.1.1.4 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Chal_sti_synt_N | 0.50 | 44.0 | 2.96e-01 | 100.0% | 26.4% |
| 3226145 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.50 | 41.0 | 3.04e-01 | 96.7% | 47.0% |
| 4211631 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.50 | 32.0 | 3.54e-01 | 96.7% | 80.0% |
D2
medium
residues 61-180
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 49.0 | 4.74e-01 | 71.7% | 72.2% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.69 | 48.0 | 4.73e-01 | 71.7% | 73.3% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 46.0 | 4.66e-01 | 71.7% | 69.5% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 46.0 | 4.72e-01 | 71.7% | 86.3% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.66 | 36.0 | 4.15e-01 | 79.2% | 73.3% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.65 | 45.0 | 3.97e-01 | 71.7% | 62.9% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.65 | 45.0 | 4.65e-01 | 70.8% | 79.6% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 45.0 | 4.61e-01 | 72.5% | 88.0% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 44.0 | 4.44e-01 | 72.5% | 81.8% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 41.0 | 3.90e-01 | 89.2% | 55.2% |
| 3n1bA02 | 1.20.1280.130 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.62 | 39.0 | 4.33e-01 | 80.8% | 78.9% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.61 | 42.0 | 3.93e-01 | 70.8% | 64.2% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 42.0 | 3.63e-01 | 73.3% | 90.4% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.58 | 41.0 | 4.10e-01 | 72.5% | 78.4% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.57 | 46.0 | 3.24e-01 | 85.0% | 33.2% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.57 | 38.0 | 3.89e-01 | 78.3% | 70.2% |
| 2xs1A01 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.57 | 45.0 | 3.23e-01 | 85.0% | 31.1% |
| 2o8pA00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.57 | 48.0 | 3.94e-01 | 91.7% | 56.6% |
| 2q24A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 50.0 | 4.40e-01 | 97.5% | 90.8% |
| 7sf7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 46.0 | 3.63e-01 | 91.7% | 54.6% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.54 | 36.0 | 3.84e-01 | 70.0% | 77.1% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.53 | 38.0 | 3.80e-01 | 85.8% | 70.1% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.53 | 41.0 | 4.02e-01 | 100.0% | 75.8% |
| 4ackB00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.52 | 45.0 | 4.16e-01 | 93.3% | 81.7% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 36.0 | 3.49e-01 | 72.5% | 76.5% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2396196 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.70 | 49.0 | 4.76e-01 | 71.7% | 77.3% |
| 3740239 | 601.1.1.96 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › VBS_C3G9 | 0.70 | 49.0 | 4.77e-01 | 71.7% | 73.8% |
| 3971927 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.70 | 42.0 | 4.98e-01 | 99.2% | 86.9% |
| 3520096 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.68 | 48.0 | 4.70e-01 | 71.7% | 77.7% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.65 | 45.0 | 4.64e-01 | 71.7% | 84.3% |
| 2756447 | 5069.1.1.5 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II | 0.64 | 45.0 | 3.94e-01 | 72.5% | 48.7% |
| 3594445 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 46.0 | 4.62e-01 | 75.0% | 77.6% |
| 3929891 | 601.16.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT | 0.64 | 44.0 | 4.35e-01 | 71.7% | 82.3% |
| 4536674 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 44.0 | 3.89e-01 | 72.5% | 84.0% |
| 3796225 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 43.0 | 4.29e-01 | 71.7% | 71.2% |
| 3463947 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.60 | 41.0 | 3.84e-01 | 70.8% | 67.3% |
| 5047796 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 47.0 | 3.77e-01 | 85.0% | 59.2% |
| 3363306 | 611.7.1.16 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB2_N | 0.59 | 40.0 | 3.76e-01 | 88.3% | 56.0% |
| 3596490 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 38.0 | 4.27e-01 | 84.2% | 86.7% |
| 3787128 | 109.4.1.654 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFB6 | 0.58 | 43.0 | 3.47e-01 | 77.5% | 53.5% |
| 3784329 | 601.1.2.75 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA | 0.56 | 50.0 | 4.20e-01 | 96.7% | 84.0% |
| 4944372 | 5073.1.2.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain | 0.56 | 45.0 | 3.45e-01 | 85.0% | 54.1% |
| 5039563 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.55 | 46.0 | 3.92e-01 | 92.5% | 83.4% |
| 5054675 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.55 | 49.0 | 4.46e-01 | 99.2% | 96.4% |
| 4222622 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.55 | 46.0 | 3.11e-01 | 93.3% | 48.0% |
| 3465019 | 601.1.1.54 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF4220 | 0.54 | 45.0 | 4.03e-01 | 92.5% | 80.6% |
| 3694308 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.54 | 40.0 | 2.70e-01 | 78.3% | 70.6% |
| 4010936 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.54 | 43.0 | 2.88e-01 | 85.8% | 71.1% |
| 3466794 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 47.0 | 3.64e-01 | 98.3% | 90.0% |
| 3418471 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.52 | 39.0 | 2.84e-01 | 78.3% | 62.8% |
| 3416020 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 46.0 | 3.33e-01 | 98.3% | 62.0% |
| 3665289 | 109.3.1.31 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4220 | 0.52 | 46.0 | 3.54e-01 | 95.0% | 67.8% |
| 3783658 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.52 | 46.0 | 3.25e-01 | 98.3% | 65.6% |
| 3532857 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 40.0 | 3.60e-01 | 81.7% | 90.3% |
| 4020809 | 149.1.1.0 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 | 0.50 | 39.0 | 2.87e-01 | 83.3% | 65.1% |