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IMGVR_UViG_3300025131_000516-3300025131-Ga0209128_10009014
Arc-VirIMGVR_UViG_3300025131_000516-3300025131-Ga0209128_10009014
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-80
Domain cluster:
representative
CATH (64)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hjrA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 68.0 | 5.35e-01 | 100.0% | 53.8% |
| 1nyrA03 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.72 | 63.0 | 4.18e-01 | 96.2% | 60.1% |
| 4ktwA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.69 | 61.0 | 4.90e-01 | 100.0% | 53.8% |
| 4h08A00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.69 | 61.0 | 4.57e-01 | 100.0% | 69.5% |
| 3cqjA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.68 | 60.0 | 4.16e-01 | 100.0% | 52.2% |
| 8gr2A01 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.68 | 61.0 | 4.58e-01 | 100.0% | 95.9% |
| 4ep4A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.68 | 59.0 | 4.72e-01 | 100.0% | 54.2% |
| 5facA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.68 | 60.0 | 4.38e-01 | 100.0% | 64.3% |
| 3rjtA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.68 | 61.0 | 4.46e-01 | 100.0% | 90.2% |
| 2pdoA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.67 | 50.0 | 4.31e-01 | 92.5% | 50.8% |
| 4htyA00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.66 | 57.0 | 3.80e-01 | 97.5% | 48.2% |
| 4c1bA02 | 3.40.50.12700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.64 | 50.0 | 4.62e-01 | 85.0% | 86.4% |
| 1z8hA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.64 | 58.0 | 4.29e-01 | 100.0% | 89.1% |
| 2derB01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.64 | 50.0 | 3.76e-01 | 97.5% | 33.5% |
| 4rw0A00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.64 | 56.0 | 4.32e-01 | 100.0% | 88.0% |
| 4nimA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 55.0 | 4.00e-01 | 100.0% | 89.6% |
| 4impA03 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 55.0 | 3.89e-01 | 100.0% | 55.9% |
| 1wraA01 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.62 | 55.0 | 3.75e-01 | 100.0% | 48.3% |
| 2aeaA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.62 | 54.0 | 3.90e-01 | 100.0% | 82.0% |
| 3iv3A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.62 | 54.0 | 3.63e-01 | 100.0% | 48.8% |
| 4iqyB00 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.62 | 56.0 | 4.04e-01 | 100.0% | 62.6% |
| 2b69A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 54.0 | 3.94e-01 | 100.0% | 72.0% |
| 3u0hA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.62 | 55.0 | 3.79e-01 | 100.0% | 52.3% |
| 6n2aB02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.60 | 53.0 | 3.85e-01 | 100.0% | 56.2% |
| 4u3aB00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.60 | 52.0 | 3.57e-01 | 97.5% | 52.7% |
| 1gcaA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 45.0 | 3.60e-01 | 83.7% | 39.8% |
| 1ad1A00 | 3.20.20.20 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like | 0.60 | 53.0 | 3.71e-01 | 100.0% | 59.1% |
| 3vu9A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 52.0 | 3.89e-01 | 100.0% | 64.2% |
| 3qtgA01 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.59 | 52.0 | 3.74e-01 | 100.0% | 55.8% |
| 1khtB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 52.0 | 3.97e-01 | 100.0% | 72.8% |
| 2pg3A00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.59 | 52.0 | 3.81e-01 | 100.0% | 70.0% |
| 2waaA02 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.58 | 51.0 | 3.80e-01 | 100.0% | 79.7% |
| 3ghfA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.58 | 48.0 | 4.51e-01 | 91.3% | 81.0% |
| 3gm8A03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.58 | 51.0 | 3.42e-01 | 100.0% | 38.4% |
| 2xryA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.58 | 49.0 | 4.13e-01 | 100.0% | 56.1% |
| 1rqeA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 51.0 | 3.48e-01 | 100.0% | 57.0% |
| 2pljA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.57 | 48.0 | 3.62e-01 | 100.0% | 58.1% |
| 2x0kA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.57 | 49.0 | 3.78e-01 | 97.5% | 41.9% |
| 4s2rP02 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.57 | 45.0 | 3.62e-01 | 86.3% | 58.9% |
| 4gu5B01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.57 | 49.0 | 4.20e-01 | 100.0% | 73.0% |
| 1xoiA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.56 | 50.0 | 3.10e-01 | 100.0% | 82.7% |
| 2h29A00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.56 | 47.0 | 3.59e-01 | 98.8% | 39.4% |
| 6r9rA01 | 3.40.50.10640 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SSO1389-like | 0.56 | 50.0 | 3.75e-01 | 100.0% | 89.8% |
| 1gg1A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.56 | 47.0 | 3.19e-01 | 97.5% | 26.8% |
| 2i0fA00 | 3.40.50.960 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase | 0.56 | 48.0 | 4.02e-01 | 100.0% | 77.6% |
| 3rpjA00 | 3.30.310.230 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Sigma factor-binding protein Crl monomer | 0.56 | 43.0 | 3.68e-01 | 82.5% | 98.4% |
| 3c65A00 | 3.30.420.340 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › UvrC, RNAse H endonuclease domain | 0.55 | 49.0 | 4.02e-01 | 100.0% | 66.9% |
| 3tpaA03 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.55 | 46.0 | 3.53e-01 | 100.0% | 58.7% |
| 1tpzA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 48.0 | 3.75e-01 | 97.5% | 84.1% |
| 2w0mA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 48.0 | 3.55e-01 | 100.0% | 45.0% |
| 1jhdA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.55 | 44.0 | 3.36e-01 | 98.8% | 35.5% |
| 6ovqA00 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.54 | 48.0 | 3.25e-01 | 100.0% | 62.9% |
| 4ysnA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 47.0 | 3.32e-01 | 100.0% | 54.5% |
| 5dn8A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.76e-01 | 100.0% | 87.7% |
| 1pz1A00 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.53 | 47.0 | 3.13e-01 | 100.0% | 47.0% |
| 6bs3B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 44.0 | 3.06e-01 | 100.0% | 93.0% |
| 1ffyA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.52 | 45.0 | 2.90e-01 | 100.0% | 82.3% |
| 3up8A00 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.52 | 45.0 | 3.13e-01 | 100.0% | 54.4% |
| 2cx6A00 | 3.30.370.10 | Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › Barstar-like | 0.52 | 44.0 | 4.35e-01 | 100.0% | 98.9% |
| 1pyfA00 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.52 | 45.0 | 3.06e-01 | 100.0% | 58.2% |
| 1xo1A02 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.52 | 44.0 | 3.60e-01 | 97.5% | 49.7% |
| 1exbA00 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.52 | 44.0 | 3.02e-01 | 100.0% | 41.4% |
| 5y58A01 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.51 | 44.0 | 3.27e-01 | 100.0% | 93.7% |
| 4m52A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.50 | 45.0 | 3.25e-01 | 98.8% | 54.5% |
ECOD (83)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3308941 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.80 | 74.0 | 5.37e-01 | 100.0% | 46.8% |
| 4218879 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.76 | 70.0 | 5.53e-01 | 100.0% | 54.8% |
| 4638438 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.75 | 69.0 | 5.43e-01 | 100.0% | 54.4% |
| 4069907 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.75 | 70.0 | 5.33e-01 | 100.0% | 51.2% |
| 3737725 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.75 | 64.0 | 4.91e-01 | 100.0% | 41.7% |
| 4631411 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.73 | 66.0 | 5.24e-01 | 100.0% | 54.4% |
| 3180133 | 2484.1.1.57 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ydc2-catalyt | 0.72 | 64.0 | 4.47e-01 | 100.0% | 49.6% |
| 3511076 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.71 | 64.0 | 5.26e-01 | 100.0% | 75.2% |
| 4579381 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.71 | 65.0 | 5.12e-01 | 100.0% | 54.4% |
| 3784998 | 2484.1.1.57 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ydc2-catalyt | 0.71 | 62.0 | 4.36e-01 | 100.0% | 43.8% |
| 4522962 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.71 | 62.0 | 4.89e-01 | 100.0% | 49.7% |
| 4952334 | 7510.1.1.0 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like | 0.71 | 62.0 | 5.23e-01 | 100.0% | 64.3% |
| 1096260 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.70 | 63.0 | 5.06e-01 | 100.0% | 53.5% |
| 4275354 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.70 | 61.0 | 4.98e-01 | 100.0% | 55.5% |
| 4529580 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.70 | 61.0 | 4.92e-01 | 100.0% | 54.4% |
| 4543638 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.69 | 61.0 | 4.87e-01 | 100.0% | 52.7% |
| 3291200 | 2007.5.1.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 | 0.69 | 62.0 | 4.46e-01 | 100.0% | 67.6% |
| 3583171 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.69 | 61.0 | 4.84e-01 | 100.0% | 89.7% |
| 4931921 | 7510.1.1.0 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like | 0.68 | 59.0 | 4.97e-01 | 100.0% | 65.0% |
| 3314969 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.68 | 62.0 | 5.04e-01 | 100.0% | 64.1% |
| 3925641 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.67 | 59.0 | 4.69e-01 | 100.0% | 64.1% |
| 4561209 | 7510.1.1.0 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like | 0.67 | 58.0 | 4.96e-01 | 100.0% | 69.6% |
| 4001806 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.66 | 59.0 | 4.59e-01 | 100.0% | 64.0% |
| 5081472 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.66 | 57.0 | 4.73e-01 | 100.0% | 75.2% |
| 5014663 | 2004.1.1.85 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase | 0.66 | 58.0 | 3.87e-01 | 100.0% | 88.5% |
| 1725866 | 2002.1.1.8 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Cellulase | 0.65 | 57.0 | 3.79e-01 | 98.8% | 47.8% |
| 5048628 | 2004.1.1.85 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase | 0.65 | 57.0 | 3.81e-01 | 100.0% | 95.2% |
| 3549056 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.65 | 58.0 | 4.47e-01 | 100.0% | 57.2% |
| 4962645 | 2007.5.1.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 | 0.65 | 58.0 | 4.20e-01 | 100.0% | 88.0% |
| 3275766 | 2007.2.3.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Syja_N | 0.65 | 56.0 | 3.82e-01 | 100.0% | 48.6% |
| 5052757 | 2004.1.1.16 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf | 0.64 | 57.0 | 4.21e-01 | 97.5% | 84.4% |
| 3512052 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.64 | 55.0 | 4.63e-01 | 100.0% | 75.2% |
| 3953416 | 129.1.1.70 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › SpnB_Rossmann | 0.63 | 56.0 | 4.12e-01 | 100.0% | 65.5% |
| 5073108 | 2004.1.1.119 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Gtr1_RagA | 0.63 | 55.0 | 4.30e-01 | 100.0% | 90.6% |
| 4944272 | 2002.1.1.44 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase | 0.63 | 56.0 | 3.92e-01 | 100.0% | 41.2% |
| 3327377 | 301.1.1.5 ↗ | a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › SpoU_sub_bind | 0.63 | 47.0 | 4.17e-01 | 100.0% | 54.2% |
| 3402807 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.63 | 56.0 | 4.51e-01 | 100.0% | 74.8% |
| 4935059 | 2002.1.1.44 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase | 0.63 | 55.0 | 3.93e-01 | 100.0% | 44.1% |
| 4966453 | 2002.1.1.44 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase | 0.62 | 56.0 | 3.90e-01 | 100.0% | 45.4% |
| 4352698 | 2004.1.1.85 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase | 0.62 | 54.0 | 3.67e-01 | 100.0% | 94.6% |
| 4984052 | 2002.1.1.44 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase | 0.62 | 55.0 | 3.89e-01 | 100.0% | 43.9% |
| None | — | 0.62 | 53.0 | 3.65e-01 | 100.0% | 94.9% | |
| 3922909 | 2007.1.14.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase | 0.62 | 49.0 | 3.24e-01 | 86.3% | 43.0% |
| 3967361 | 301.3.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › OmpA-like › OmpA-like › OmpA | 0.61 | 51.0 | 4.49e-01 | 92.5% | 68.1% |
| 3405383 | 2005.1.1.36 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 | 0.61 | 52.0 | 3.94e-01 | 100.0% | 69.8% |
| 4009305 | 300.1.1.8 ↗ | a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_2 | 0.60 | 52.0 | 4.13e-01 | 96.2% | 59.4% |
| 4223347 | 2002.1.1.11 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PK | 0.60 | 53.0 | 3.80e-01 | 100.0% | 53.9% |
| 5052305 | 2004.1.1.119 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Gtr1_RagA | 0.60 | 51.0 | 4.06e-01 | 100.0% | 91.0% |
| 4346434 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.59 | 51.0 | 4.32e-01 | 100.0% | 56.5% |
| 3972418 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.59 | 51.0 | 4.28e-01 | 97.5% | 56.3% |
| 4946557 | 2004.1.1.119 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Gtr1_RagA | 0.59 | 53.0 | 4.06e-01 | 100.0% | 83.3% |
| 3995439 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.59 | 44.0 | 4.24e-01 | 82.5% | 69.5% |
| 4026627 | 2002.1.1.30 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 | 0.58 | 51.0 | 3.35e-01 | 100.0% | 61.5% |
| 4959831 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.58 | 47.0 | 4.12e-01 | 100.0% | 57.7% |
| 4308712 | 2005.1.1.9 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › DNA_photolyase | 0.58 | 49.0 | 3.80e-01 | 100.0% | 43.0% |
| 3321664 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.57 | 49.0 | 3.18e-01 | 100.0% | 36.3% |
| 5059127 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.57 | 50.0 | 4.28e-01 | 100.0% | 76.9% |
| 4938423 | 7512.1.1.32 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 | 0.57 | 47.0 | 3.58e-01 | 98.8% | 36.6% |
| 4934180 | 2006.1.6.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like | 0.56 | 48.0 | 3.66e-01 | 100.0% | 84.8% |
| 4409071 | 2007.1.6.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain › THF_DHG_CYH | 0.56 | 43.0 | 3.89e-01 | 85.0% | 74.8% |
| 5046757 | 2005.1.1.9 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › DNA_photolyase | 0.56 | 47.0 | 3.60e-01 | 98.8% | 39.0% |
| 5060575 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.56 | 48.0 | 4.41e-01 | 100.0% | 96.4% |
| 4467060 | 2004.1.1.196 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 | 0.56 | 47.0 | 3.55e-01 | 100.0% | 36.3% |
| 3806185 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.55 | 50.0 | 3.09e-01 | 100.0% | 33.8% |
| 4299491 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.55 | 48.0 | 3.96e-01 | 100.0% | 60.7% |
| 152052 | 2007.1.13.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase › DMRL_synthase | 0.55 | 47.0 | 3.87e-01 | 100.0% | 81.6% |
| 1758615 | 301.9.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › HypA Ni-binding domain › HypA Ni-binding domain › HypA | 0.54 | 39.0 | 3.89e-01 | 81.2% | 72.1% |
| 4952925 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.54 | 45.0 | 3.29e-01 | 97.5% | 57.7% |
| 3493561 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.54 | 45.0 | 3.43e-01 | 100.0% | 78.5% |
| 4330559 | 301.9.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › HypA Ni-binding domain › HypA Ni-binding domain › HypA | 0.54 | 39.0 | 3.54e-01 | 83.7% | 54.8% |
| 5043928 | 2004.1.1.277 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › HerA_C | 0.54 | 37.0 | 3.04e-01 | 88.7% | 36.9% |
| 4978859 | 2494.1.1.2 ↗ | a/b three-layered sandwiches › DTD-like › DTD-like (Pfam 02580) › DTD-like (Pfam 02580) › tRNA-Thr_ED | 0.53 | 46.0 | 3.92e-01 | 100.0% | 83.6% |
| 3709495 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.53 | 46.0 | 4.12e-01 | 98.8% | 90.4% |
| 3601487 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 44.0 | 2.61e-01 | 98.8% | 32.0% |
| 4936110 | 4244.1.1.0 ↗ | a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like | 0.52 | 44.0 | 3.47e-01 | 97.5% | 48.3% |
| 4958034 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.52 | 43.0 | 3.26e-01 | 100.0% | 35.8% |
| 3181438 | 7590.1.1.7 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › MID_MedPIWI | 0.51 | 42.0 | 3.21e-01 | 100.0% | 56.0% |
| 5075893 | 4143.1.1.1 ↗ | a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like › THUMP | 0.51 | 42.0 | 3.84e-01 | 92.5% | 100.0% |
| 3376596 | 2002.1.2.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 | 0.50 | 43.0 | 3.69e-01 | 100.0% | 95.0% |
| 4194046 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.50 | 43.0 | 3.37e-01 | 100.0% | 55.3% |
| 3409128 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.50 | 43.0 | 3.32e-01 | 97.5% | 63.7% |
| 3821194 | 7568.1.1.4 ↗ | a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 | 0.50 | 43.0 | 3.87e-01 | 98.8% | 94.1% |
| 4978823 | 4143.1.1.1 ↗ | a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like › THUMP | 0.50 | 40.0 | 3.85e-01 | 92.5% | 75.8% |
D2
medium
residues 81-142
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.73 | 50.0 | 4.35e-01 | 71.0% | 53.3% |
| 3fmcC01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.72 | 50.0 | 3.18e-01 | 72.6% | 38.3% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.67 | 46.0 | 3.98e-01 | 71.0% | 78.9% |
| 1cukA02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.63 | 36.0 | 3.41e-01 | 85.5% | 46.1% |
| 1rm6B02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.60 | 41.0 | 3.51e-01 | 72.6% | 70.1% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.58 | 39.0 | 3.72e-01 | 71.0% | 70.3% |
| 3l8kA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 48.0 | 3.33e-01 | 95.2% | 90.8% |
| 2lfhA00 | 4.10.280.10 | Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain | 0.57 | 45.0 | 4.39e-01 | 90.3% | 80.9% |
| 1dj8A00 | 1.10.890.10 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › HNS-dependent expression A | 0.57 | 44.0 | 4.10e-01 | 85.5% | 89.9% |
| 2looA02 | 1.10.10.1740 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Transmembrane protein 14-like | 0.56 | 38.0 | 3.59e-01 | 71.0% | 72.0% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.55 | 45.0 | 3.42e-01 | 91.9% | 72.0% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.55 | 39.0 | 3.52e-01 | 91.9% | 54.0% |
| 2kvuA00 | 1.10.720.30 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain | 0.54 | 41.0 | 3.94e-01 | 91.9% | 69.3% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 39.0 | 2.96e-01 | 77.4% | 61.5% |
| 2qbyA01 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 39.0 | 3.38e-01 | 79.0% | 87.4% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.53 | 38.0 | 3.80e-01 | 77.4% | 76.9% |
| 3l4aA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.53 | 39.0 | 3.24e-01 | 82.3% | 70.2% |
| 4ua8A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.53 | 41.0 | 2.93e-01 | 85.5% | 79.4% |
| 1y56B01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 42.0 | 2.95e-01 | 91.9% | 41.3% |
| 4o6kA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 38.0 | 3.08e-01 | 83.9% | 96.3% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.51 | 39.0 | 3.23e-01 | 85.5% | 79.0% |
| 3llkA01 | 1.20.120.1960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › QSOX sulfhydryl oxidase domain | 0.50 | 39.0 | 3.42e-01 | 87.1% | 76.5% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3182631 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.60 | 42.0 | 3.76e-01 | 75.8% | 62.1% |
| 3686033 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.58 | 45.0 | 2.83e-01 | 85.5% | 57.7% |
| 3408361 | 632.23.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I › DUF4485 | 0.58 | 42.0 | 3.82e-01 | 77.4% | 91.8% |
| 3386111 | 6130.1.1.0 ↗ | alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain | 0.58 | 42.0 | 4.05e-01 | 91.9% | 68.6% |
| 3569684 | 108.1.1.95 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › CCD48 | 0.58 | 41.0 | 3.59e-01 | 75.8% | 71.6% |
| 4948274 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.57 | 40.0 | 3.76e-01 | 72.6% | 69.3% |
| 5070806 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.56 | 41.0 | 4.11e-01 | 79.0% | 98.5% |
| 4507131 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.56 | 43.0 | 2.66e-01 | 83.9% | 49.4% |
| 3430911 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.55 | 41.0 | 3.78e-01 | 87.1% | 61.3% |
| 3687243 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 38.0 | 3.66e-01 | 71.0% | 75.7% |
| 3935349 | 108.1.1.14 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF_assoc_2 | 0.55 | 40.0 | 3.36e-01 | 91.9% | 44.5% |
| 3488752 | 101.1.21.1 ↗ | alpha arrays › HTH › HTH › HTH in T7 RNA polymerase › RPOL_N | 0.54 | 38.0 | 2.52e-01 | 75.8% | 42.5% |
| 3219497 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.53 | 39.0 | 3.78e-01 | 88.7% | 67.1% |
| 4527373 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.53 | 39.0 | 3.67e-01 | 80.6% | 92.5% |
| 4170537 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.53 | 38.0 | 2.98e-01 | 75.8% | 39.2% |
| 4363284 | 148.1.3.203 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF28760 | 0.52 | 38.0 | 3.06e-01 | 82.3% | 79.3% |
| 3425274 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.51 | 42.0 | 3.25e-01 | 96.8% | 54.2% |
| 3415557 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.50 | 39.0 | 3.11e-01 | 88.7% | 77.1% |