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IMGVR_UViG_3300025146_000395-3300025146-Ga0209322_1000275519

Arc-Vir

IMGVR_UViG_3300025146_000395-3300025146-Ga0209322_1000275519

Quality

90.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-67
PDB
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2q7sA00 3.40.630.40 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn-dependent exopeptidases 0.67 57.0 3.85e-01 97.0% 80.4%
5ksoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 42.0 3.21e-01 70.1% 39.2%
3vkgA07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 46.0 2.87e-01 80.6% 49.1%
1hezE00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 33.0 3.44e-01 86.6% 60.7%
1xjcA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 41.0 3.21e-01 74.6% 93.1%
1np6B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 41.0 3.30e-01 79.1% 91.2%
3m9gA03 3.30.10.20 Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › 0.54 40.0 4.03e-01 86.6% 79.1%
1ryhA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 40.0 3.03e-01 82.1% 54.4%
6j09A04 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.53 36.0 3.47e-01 85.1% 61.0%
1knyA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 39.0 3.25e-01 95.5% 42.4%
3mnfA00 3.40.50.10900 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit 0.53 45.0 3.16e-01 97.0% 74.9%
3m9gA02 3.30.10.20 Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › 0.53 40.0 4.01e-01 88.1% 82.4%
3netB01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.53 43.0 2.91e-01 100.0% 93.7%
4rkrD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 43.0 3.42e-01 95.5% 93.8%
3l3bA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.51 44.0 3.21e-01 100.0% 85.7%
3p8aA02 2.60.40.4320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 41.0 3.76e-01 91.0% 93.3%
6z30A01 2.70.130.10 Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain 0.50 42.0 3.44e-01 97.0% 91.0%
5e0yA00 3.30.10.20 Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › 0.50 38.0 3.86e-01 86.6% 83.8%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4967466 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.77 64.0 5.45e-01 97.0% 57.1%
5084062 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.76 62.0 5.27e-01 100.0% 56.2%
4483252 2498.1.1.22 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YbeY 0.73 63.0 4.91e-01 100.0% 54.0%
4929424 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.72 61.0 5.40e-01 95.5% 66.0%
3574082 2498.1.1.39 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like 0.72 58.0 5.27e-01 100.0% 65.6%
3822567 5.1.3.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.68 47.0 2.98e-01 97.0% 15.3%
4501680 2498.1.1.22 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YbeY 0.67 59.0 4.69e-01 100.0% 53.6%
5050240 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.61 54.0 3.70e-01 100.0% 28.9%
3318551 323.1.1.7 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.60 50.0 3.54e-01 100.0% 78.8%
3726253 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.59 44.0 3.07e-01 79.1% 36.6%
4945353 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 42.0 3.16e-01 77.6% 92.4%
3666172 323.1.1.7 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.57 46.0 3.35e-01 97.0% 79.1%
3610113 109.4.1.18 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA 0.57 44.0 2.76e-01 86.6% 14.1%
4024542 211.1.1.1 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.57 39.0 4.07e-01 70.1% 91.7%
3280391 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.56 40.0 4.02e-01 76.1% 81.4%
4267972 2003.1.5.49 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.56 37.0 2.55e-01 70.1% 38.8%
4670926 2003.1.5.49 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.55 41.0 2.77e-01 80.6% 88.9%
3616983 2007.2.5.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.54 34.0 2.73e-01 95.5% 29.3%
3605008 316.1.1.5 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RsfS 0.54 46.0 3.28e-01 95.5% 35.7%
3273216 3940.1.1.0 a+b two layers › Spliceosomal helicase Aquarius insert domain › Spliceosomal helicase Aquarius insert domain › Spliceosomal helicase Aquarius insert domain 0.54 38.0 4.01e-01 88.1% 85.0%
3170820 63.1.1.4 beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › PRKCSH_1 0.53 45.0 3.57e-01 98.5% 89.2%
4976993 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.53 43.0 3.56e-01 98.5% 47.9%
3750274 63.1.1.1 beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › CIMR 0.52 44.0 3.52e-01 98.5% 85.5%
4429064 294.2.1.1 a+b two layers › CI-2 family of serine protease inhibitors-like › Penicillin-binding protein 2x (pbp-2x)-C › Penicillin-binding protein 2x (pbp-2x)-C › PASTA 0.52 39.0 4.03e-01 82.1% 84.6%
None 0.52 44.0 3.51e-01 98.5% 84.8%
3942645 3070.1.1.0 a+b complex topology › N0 domain in phage tail proteins and secretins-like › N0 domain in phage tail proteins and secretins › N0 domain in phage tail proteins and secretins 0.52 40.0 3.59e-01 86.6% 72.0%
4149038 2011.2.1.3 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro 0.52 45.0 3.28e-01 98.5% 62.4%
3226145 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 43.0 3.12e-01 91.0% 34.6%
4420868 294.2.1.1 a+b two layers › CI-2 family of serine protease inhibitors-like › Penicillin-binding protein 2x (pbp-2x)-C › Penicillin-binding protein 2x (pbp-2x)-C › PASTA 0.51 39.0 3.91e-01 88.1% 81.2%
3610989 2498.5.1.0 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like 0.51 43.0 3.77e-01 100.0% 100.0%
3428250 2007.5.1.20 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › PC-Esterase,PMR5N 0.51 37.0 2.36e-01 77.6% 79.1%
3339963 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 42.0 2.91e-01 100.0% 78.9%
4240625 4212.1.1.1 beta barrels › FimD N-terminal domain-like › FimD N-terminal domain-like › FimD N-terminal domain-like › PapC_N 0.50 35.0 3.14e-01 71.6% 93.3%
3724686 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 41.0 3.23e-01 98.5% 92.9%
D2 medium residues 68-120
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.77 64.0 5.77e-01 90.6% 78.9%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.77 57.0 3.87e-01 79.2% 23.5%
2g8lA02 1.10.285.20 Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 0.76 54.0 5.05e-01 83.0% 61.5%
1t98A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 55.0 4.67e-01 79.2% 50.6%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.73 56.0 5.22e-01 84.9% 88.2%
2g5gX02 1.10.8.760 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Haem-binding uptake, Tiki superfamily, ChaN, domain 2 0.71 54.0 5.25e-01 83.0% 72.9%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.70 61.0 5.31e-01 100.0% 69.9%
2j82A00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.68 55.0 3.70e-01 94.3% 53.8%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.64 47.0 3.50e-01 81.1% 61.0%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 46.0 3.18e-01 81.1% 75.2%
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 50.0 4.21e-01 94.3% 51.0%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.61 45.0 4.62e-01 84.9% 92.3%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.60 47.0 4.03e-01 96.2% 62.1%
1w8iA00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.58 48.0 3.50e-01 94.3% 47.4%
4ragA02 1.10.10.430 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphatase 2C, C-terminal domain suprefamily 0.58 40.0 3.81e-01 77.4% 58.8%
1kblA05 1.20.80.30 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.57 46.0 3.98e-01 92.5% 66.3%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.56 40.0 3.10e-01 75.5% 48.3%
2af6A02 6.10.140.450 Special › Helix non-globular › Helix Hairpins › 0.54 38.0 3.65e-01 73.6% 72.6%
4u2vA02 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.54 40.0 3.60e-01 83.0% 55.0%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.54 39.0 3.15e-01 75.5% 42.1%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 35.0 3.41e-01 75.5% 60.7%
1ks9A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 39.0 3.05e-01 84.9% 37.4%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.51 37.0 3.46e-01 75.5% 89.1%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.51 39.0 3.57e-01 94.3% 74.4%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.51 36.0 3.38e-01 75.5% 89.6%
3zdmB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.51 36.0 3.68e-01 81.1% 78.0%
4kjmB01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.50 40.0 3.79e-01 86.8% 82.5%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5067100 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.74 59.0 5.09e-01 92.5% 55.3%
4913800 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.67 52.0 4.58e-01 84.9% 59.5%
3250201 101.1.1.21 alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 0.66 50.0 4.79e-01 90.6% 70.8%
3545789 3542.1.1.12 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › TM7S3_TM198 0.64 55.0 3.72e-01 100.0% 32.7%
4948317 103.5.1.0 alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like 0.62 46.0 4.71e-01 90.6% 88.0%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.62 53.0 3.43e-01 94.3% 25.1%
136740 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.60 47.0 3.55e-01 90.6% 75.5%
4496489 2498.4.1.0 mixed a+b and a/b › Zincin-like › HSP90 C-terminal domain (C-terminal part of Pfam 00183) › HSP90 C-terminal domain (C-terminal part of Pfam 00183) 0.59 45.0 3.07e-01 84.9% 42.4%
3217232 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 46.0 3.98e-01 86.8% 74.1%
4547274 3714.1.1.0 a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain 0.59 44.0 3.69e-01 84.9% 45.0%
4012407 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.54 39.0 3.72e-01 75.5% 66.7%
4520607 131.1.1.3 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD 0.54 44.0 3.18e-01 100.0% 61.1%
3789403 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.53 41.0 2.77e-01 92.5% 81.9%
4964664 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.53 40.0 3.66e-01 77.4% 64.6%
3256686 568.1.1.0 few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related 0.52 41.0 4.06e-01 84.9% 87.3%
3805996 192.10.1.7 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › HisKA 0.52 39.0 3.41e-01 79.2% 56.0%
3732192 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.51 39.0 3.40e-01 79.2% 56.0%
3264065 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.51 39.0 3.33e-01 79.2% 52.5%
3973158 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.51 39.0 3.33e-01 79.2% 52.5%
4986977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.51 38.0 3.57e-01 79.2% 64.6%
4944568 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.51 38.0 3.52e-01 79.2% 64.6%
5002349 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.50 38.0 3.53e-01 79.2% 64.6%