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IMGVR_UViG_3300025159_000046-3300025159-Ga0209619_100033295

Arc-Vir

IMGVR_UViG_3300025159_000046-3300025159-Ga0209619_100033295

Quality

84.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-82
PDB
D2 medium residues 83-212
PDB
D3 medium residues 248-351
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ew2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.61 43.0 4.00e-01 73.1% 93.3%
2nogB02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.59 37.0 4.26e-01 80.8% 92.9%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 42.0 3.81e-01 76.0% 88.9%
3p7nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 33.0 3.77e-01 75.0% 83.3%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.54 38.0 3.49e-01 72.1% 85.5%
2qzcA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 39.0 3.15e-01 81.7% 95.7%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4978272 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.76 69.0 6.74e-01 100.0% 93.9%
4935112 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.75 69.0 6.56e-01 100.0% 91.7%
5049375 182.1.2.1 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Fe-S cluster domain of DNA primase › DNA_primase_lrg 0.74 67.0 6.15e-01 100.0% 91.9%
5072206 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.74 67.0 6.37e-01 99.0% 96.7%
4103318 182.1.2.1 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Fe-S cluster domain of DNA primase › DNA_primase_lrg 0.73 66.0 6.06e-01 100.0% 80.0%
3962643 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.53 38.0 3.36e-01 76.0% 70.0%
3596950 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.52 44.0 3.64e-01 99.0% 91.4%
D4 medium residues 587-713
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06048.18 best DUF927 41.9 1.40e-10 77.2% 29.2%
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 63.0 5.30e-01 100.0% 56.4%
3ja8204 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 62.0 4.51e-01 96.9% 41.1%
4pytA01 3.30.43.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 0.67 31.0 3.65e-01 88.2% 61.4%
1g8pA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 60.0 5.19e-01 98.4% 83.4%
3m6aA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 55.0 5.24e-01 100.0% 75.3%
4zpxA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 59.0 4.84e-01 97.6% 79.0%
4fw9A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 59.0 4.54e-01 97.6% 78.4%
3t15A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 58.0 5.44e-01 100.0% 78.1%
1w5sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 58.0 5.05e-01 100.0% 82.1%
5ul3A01 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.63 45.0 4.24e-01 87.4% 59.6%
3vkgA07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 4.05e-01 100.0% 45.0%
3vkhB07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 55.0 4.83e-01 97.6% 75.1%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 54.0 4.44e-01 94.5% 58.6%
2qbyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 54.0 4.85e-01 98.4% 80.3%
1a2oA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 38.0 3.83e-01 86.6% 61.7%
3sylA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 53.0 4.55e-01 100.0% 63.3%
2p6rA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 4.27e-01 91.3% 77.8%
4p53A01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 49.0 4.50e-01 93.7% 95.3%
1ta9B01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 48.0 4.55e-01 91.3% 99.3%
2gruA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 48.0 4.42e-01 93.7% 95.3%
1o2dA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 47.0 4.24e-01 90.6% 97.7%
2i7xA02 3.40.50.10890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 43.0 3.80e-01 81.9% 100.0%
8oosG01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 49.0 4.20e-01 97.6% 81.8%
3uhjC01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 48.0 4.51e-01 93.7% 97.4%
1hjzA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.55 49.0 4.31e-01 100.0% 95.8%
1nmoA02 3.40.1390.30 Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › NIF3 (NGG1p interacting factor 3)-like 0.55 34.0 3.46e-01 85.8% 63.1%
2nxwA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.54 46.0 3.98e-01 92.1% 68.9%
2j62A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 48.0 3.62e-01 99.2% 91.5%
5d8nA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 46.0 4.06e-01 94.5% 92.6%
3jruA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 43.0 4.00e-01 88.2% 100.0%
1gg1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 46.0 3.48e-01 100.0% 84.4%
3h16B00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.52 40.0 3.99e-01 95.3% 76.6%
5ntfA01 3.40.50.10590 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Zn-dependent exopeptidases 0.52 43.0 3.88e-01 90.6% 92.8%
2c31A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.52 44.0 3.85e-01 90.6% 64.9%
1bmtA02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.52 43.0 4.02e-01 89.0% 85.4%
2wnsA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 44.0 3.80e-01 91.3% 100.0%
3nl6B01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 44.0 3.74e-01 95.3% 83.0%
6ln0A01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.51 46.0 4.24e-01 100.0% 95.7%
1gzdA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 41.0 3.19e-01 90.6% 82.4%
6n2aB02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.50 43.0 3.60e-01 96.1% 86.7%
1y44A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.50 40.0 3.18e-01 85.8% 97.0%
ECOD (71)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018481 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.87 80.0 5.93e-01 100.0% 42.5%
3975473 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.87 79.0 5.83e-01 100.0% 41.4%
1883334 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.85 72.0 5.46e-01 100.0% 41.5%
3944606 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.83 76.0 5.71e-01 100.0% 43.5%
4931926 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.78 67.0 4.88e-01 100.0% 36.2%
2810781 8001.1.1.1 alpha arrays › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › PPV_E1_C 0.74 63.0 5.15e-01 100.0% 51.6%
None 0.74 63.0 5.53e-01 92.9% 63.9%
5013281 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.74 67.0 5.07e-01 97.6% 46.0%
3291643 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.74 66.0 5.35e-01 96.1% 61.3%
None 0.73 63.0 5.81e-01 94.5% 73.1%
None 0.72 62.0 5.61e-01 94.5% 68.8%
3253892 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.71 59.0 5.10e-01 95.3% 57.4%
4002451 2004.1.1.93 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynein_heavy 0.71 60.0 5.23e-01 93.7% 61.1%
4030223 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.71 66.0 5.09e-01 100.0% 53.3%
3594982 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.71 66.0 5.13e-01 100.0% 52.7%
3256248 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.71 50.0 4.85e-01 90.6% 65.7%
3703312 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 66.0 4.55e-01 100.0% 57.5%
None 0.70 62.0 5.64e-01 98.4% 71.2%
4033843 2004.1.1.313 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › VapE-like_dom 0.70 57.0 4.94e-01 100.0% 56.4%
3839782 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.70 62.0 4.86e-01 95.3% 64.6%
3968271 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.68 62.0 5.20e-01 98.4% 63.8%
4552869 2004.1.1.2 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 62.0 5.09e-01 97.6% 70.9%
5063952 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.68 59.0 4.66e-01 94.5% 51.5%
4994590 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 62.0 5.20e-01 100.0% 61.4%
5023501 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.67 59.0 4.66e-01 95.3% 76.9%
4308308 2004.1.1.771 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_lid_NAV1 0.67 61.0 4.39e-01 97.6% 41.2%
5048100 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.67 62.0 4.87e-01 100.0% 68.2%
5060364 2004.1.1.22 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activat 0.67 58.0 5.28e-01 92.9% 75.2%
4973289 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 60.0 4.69e-01 100.0% 46.8%
3469175 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 61.0 4.98e-01 100.0% 69.6%
3610966 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 61.0 4.68e-01 100.0% 52.9%
4986568 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 57.0 4.57e-01 92.9% 69.2%
4971317 2004.1.1.196 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.66 59.0 4.95e-01 97.6% 80.5%
3839744 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 61.0 4.74e-01 100.0% 60.0%
4974760 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 58.0 5.00e-01 94.5% 75.9%
4218663 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 59.0 5.03e-01 97.6% 70.7%
5034518 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.66 60.0 5.02e-01 100.0% 61.9%
4224436 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 59.0 4.64e-01 98.4% 89.2%
3285371 2004.1.1.196 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.65 55.0 5.11e-01 91.3% 72.9%
3947318 7512.1.1.3 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.65 37.0 3.22e-01 74.8% 36.4%
4974815 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 58.0 5.03e-01 97.6% 70.8%
4999357 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 58.0 4.40e-01 100.0% 64.0%
4027017 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 57.0 4.55e-01 100.0% 72.9%
3443027 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.61 54.0 4.94e-01 94.5% 77.6%
4930996 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 54.0 4.57e-01 98.4% 68.1%
3373392 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.60 52.0 4.17e-01 92.9% 52.7%
3367240 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.59 52.0 4.74e-01 95.3% 80.0%
1600541 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.58 53.0 4.41e-01 100.0% 57.3%
3598922 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 50.0 4.39e-01 96.9% 77.4%
4021671 2004.1.1.366 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N 0.57 52.0 4.21e-01 99.2% 72.3%
5079035 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.57 46.0 3.85e-01 87.4% 87.7%
4972225 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.56 46.0 3.61e-01 87.4% 83.4%
4946440 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 44.0 3.79e-01 83.5% 87.0%
3514468 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.55 45.0 3.94e-01 88.2% 87.4%
4408584 2002.1.1.28 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PRAI 0.55 43.0 3.56e-01 81.9% 96.9%
3679034 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.55 49.0 3.62e-01 97.6% 67.6%
3587634 2007.1.7.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes 0.55 47.0 4.33e-01 93.7% 95.8%
4180338 7529.1.1.3 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Peptidase_M17_N 0.55 48.0 4.45e-01 98.4% 100.0%
4115562 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.55 46.0 3.89e-01 90.6% 82.4%
4929956 2002.1.1.113 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › CdhD 0.55 49.0 3.88e-01 100.0% 85.6%
4329667 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.54 45.0 3.88e-01 88.2% 86.7%
3386243 7529.1.1.0 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like 0.54 48.0 4.49e-01 98.4% 100.0%
4036693 7529.1.1.3 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Peptidase_M17_N 0.54 47.0 4.29e-01 97.6% 100.0%
4953117 2004.1.1.120 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.54 48.0 4.30e-01 97.6% 78.9%
3089043 2004.1.1.120 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.54 48.0 4.22e-01 98.4% 77.7%
3488655 7563.1.1.6 a/b three-layered sandwiches › MCP/YpsA-related › MCP/YpsA-related › MCP/YpsA-related › LSDAT_euk 0.53 46.0 3.45e-01 96.1% 73.9%
4054748 2003.1.7.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom 0.53 44.0 3.79e-01 89.8% 87.8%
4048200 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.53 44.0 3.31e-01 92.9% 86.5%
4342185 7529.1.1.3 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Peptidase_M17_N 0.52 46.0 4.20e-01 97.6% 97.6%
3689569 2003.1.1.42 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_2 0.52 41.0 3.60e-01 86.6% 90.5%
4937591 314.1.1.2 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.51 39.0 2.98e-01 82.7% 77.8%
D5 medium residues 751-836
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.70 55.0 4.58e-01 84.9% 61.1%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 53.0 5.04e-01 84.9% 75.5%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.64 45.0 4.94e-01 73.3% 100.0%
2iw3A02 1.20.1390.20 Mainly Alpha › Up-down Bundle › PWI domain › 0.62 44.0 4.42e-01 81.4% 72.2%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 48.0 4.13e-01 87.2% 60.7%
1h3lB00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.61 46.0 4.80e-01 81.4% 94.9%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.56 39.0 3.55e-01 72.1% 52.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 39.0 2.75e-01 75.6% 71.2%
2e8oA01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.54 32.0 3.64e-01 73.3% 80.6%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4024385 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.73 54.0 4.46e-01 76.7% 71.7%
3290489 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.72 56.0 5.11e-01 83.7% 70.4%
4028244 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.71 54.0 4.21e-01 80.2% 59.4%
4027540 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.70 54.0 4.32e-01 80.2% 66.9%
3739839 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.64 46.0 4.26e-01 74.4% 84.5%
4295514 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.60 42.0 3.91e-01 70.9% 73.3%
4240705 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.58 39.0 4.01e-01 70.9% 78.8%
3789972 5050.1.1.5 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier 0.58 42.0 3.28e-01 76.7% 63.8%
4991391 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.55 44.0 4.26e-01 87.2% 84.0%
3616218 633.24.1.6 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › PF26202 0.55 37.0 3.10e-01 70.9% 43.0%
3720244 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.53 43.0 3.06e-01 89.5% 30.5%
4094756 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 39.0 2.85e-01 81.4% 36.4%
D6 medium residues 838-971
PDB
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6az6A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 36.0 4.64e-01 88.1% 92.0%
2ek5B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 36.0 4.00e-01 88.8% 66.1%
6cc0A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 31.0 4.10e-01 91.8% 88.6%
3ulqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 29.0 4.09e-01 87.3% 98.3%
3lmmC04 1.10.10.2340 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.63 34.0 4.13e-01 96.3% 81.6%
4tv7D01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 32.0 3.96e-01 88.1% 81.2%
7u37A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 31.0 4.09e-01 80.6% 100.0%
3dteA02 1.10.10.1030 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › IrrE, HTH domain 0.60 23.0 3.43e-01 80.6% 100.0%
3h0dA01 3.30.56.130 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › Transcriptional regulator CtsR, winged HTH domain 0.59 32.0 4.08e-01 85.8% 95.8%
6uglB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 27.0 3.68e-01 93.3% 91.4%
5z4zC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 32.0 3.81e-01 92.5% 80.7%
1s7hA01 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 27.0 3.42e-01 72.4% 77.5%
2qbyB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 34.0 3.99e-01 91.8% 93.4%
2cfoA05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.53 35.0 3.87e-01 91.8% 85.6%
4e4tA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.52 39.0 3.47e-01 79.9% 95.0%
2mdaA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.50 32.0 3.65e-01 84.3% 88.4%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5051627 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 36.0 4.82e-01 86.6% 88.6%
3981665 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 55.0 5.99e-01 85.8% 95.5%
5059917 101.1.2.279 alpha arrays › HTH › HTH › winged helix domain › AbiEi_4 0.71 35.0 4.79e-01 87.3% 96.9%
3739178 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 34.0 4.71e-01 85.8% 100.0%
5081852 101.1.2.837 alpha arrays › HTH › HTH › winged helix domain › Lin1244_N 0.68 36.0 4.30e-01 98.5% 75.6%
3385907 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.67 29.0 4.17e-01 80.6% 94.5%
3515383 101.1.15.1 alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.65 42.0 4.72e-01 93.3% 86.0%
3180104 101.1.15.1 alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.63 35.0 4.04e-01 91.0% 76.7%
5045992 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 31.0 3.28e-01 84.3% 49.6%
4301783 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.62 27.0 3.81e-01 90.3% 86.7%
3927026 101.1.1.195 alpha arrays › HTH › HTH › Three-helical HTH › HTH_5 0.61 29.0 3.47e-01 85.8% 65.9%
4104868 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.61 27.0 3.70e-01 93.3% 83.1%
4933755 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.60 40.0 4.16e-01 97.0% 72.0%
5064574 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.60 26.0 3.70e-01 93.3% 88.3%
3651470 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.57 31.0 3.14e-01 86.6% 50.0%
3491972 108.1.1.28 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_6,EF-hand_7 0.57 29.0 3.66e-01 86.6% 84.0%
4944756 3604.1.1.0 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain 0.57 25.0 3.53e-01 90.3% 88.3%
5038689 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 36.0 4.08e-01 87.3% 85.0%
3304545 108.1.1.96 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 0.56 29.0 3.49e-01 85.8% 75.3%
3953587 2008.1.1.168 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF30184 0.56 37.0 4.20e-01 100.0% 91.0%
5045098 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.53 34.0 4.03e-01 91.0% 95.6%
5065308 101.1.2.101 alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.53 37.0 3.91e-01 92.5% 80.8%
5076192 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.53 30.0 3.85e-01 85.8% 100.0%
4962870 101.1.2.101 alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.51 41.0 4.23e-01 100.0% 91.9%
3591556 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 37.0 4.09e-01 89.6% 96.2%
3983446 101.1.2.84 alpha arrays › HTH › HTH › winged helix domain › CaiF_GrlA 0.50 34.0 3.84e-01 90.3% 92.0%
5031772 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.50 28.0 3.55e-01 79.1% 94.7%