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IMGVR_UViG_3300025159_000046-3300025159-Ga0209619_100033296
Arc-VirIMGVR_UViG_3300025159_000046-3300025159-Ga0209619_100033296
Identity
- Kingdom:
- archaea
Quality
45.4
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 539-604
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.83 | 65.0 | 5.64e-01 | 83.3% | 71.1% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.82 | 60.0 | 5.33e-01 | 77.3% | 72.0% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 64.0 | 4.33e-01 | 83.3% | 24.8% |
| 8g0lB01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.80 | 58.0 | 3.57e-01 | 80.3% | 13.4% |
| 6xssA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.79 | 56.0 | 5.53e-01 | 83.3% | 71.0% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 61.0 | 4.92e-01 | 83.3% | 86.9% |
| 1td6A01 | 1.20.1480.10 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 | 0.78 | 71.0 | 6.08e-01 | 100.0% | 72.5% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.77 | 61.0 | 4.58e-01 | 83.3% | 86.7% |
| 4ui9Y03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.77 | 54.0 | 5.12e-01 | 83.3% | 61.3% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 59.0 | 5.65e-01 | 81.8% | 88.0% |
| 2vkjA00 | 1.20.58.2030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 56.0 | 4.76e-01 | 83.3% | 49.1% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 57.0 | 5.51e-01 | 81.8% | 90.7% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 66.0 | 6.04e-01 | 97.0% | 92.9% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 65.0 | 6.01e-01 | 100.0% | 93.0% |
| 2e2eA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.73 | 64.0 | 4.78e-01 | 93.9% | 51.0% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 67.0 | 4.70e-01 | 100.0% | 89.3% |
| 8amzS01 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.72 | 55.0 | 3.35e-01 | 81.8% | 13.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 57.0 | 5.00e-01 | 84.8% | 92.7% |
| 2xpiD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 60.0 | 3.54e-01 | 100.0% | 12.0% |
| 3vkgB03 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.69 | 59.0 | 4.37e-01 | 90.9% | 52.6% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 53.0 | 4.52e-01 | 83.3% | 96.3% |
| 2gw1A02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 59.0 | 3.67e-01 | 95.5% | 21.7% |
| 3ma5A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 59.0 | 5.28e-01 | 93.9% | 85.6% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.68 | 56.0 | 5.00e-01 | 87.9% | 86.7% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 61.0 | 4.78e-01 | 100.0% | 60.7% |
| 4lctB00 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 62.0 | 3.82e-01 | 100.0% | 42.2% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.67 | 57.0 | 3.90e-01 | 93.9% | 60.7% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 51.0 | 4.56e-01 | 81.8% | 88.2% |
| 1l8nA03 | 3.90.1330.10 | Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain | 0.67 | 57.0 | 4.03e-01 | 95.5% | 82.4% |
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 58.0 | 4.29e-01 | 95.5% | 45.6% |
| 5b00A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.66 | 57.0 | 3.85e-01 | 98.5% | 34.5% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.66 | 51.0 | 3.89e-01 | 84.8% | 68.0% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.63 | 47.0 | 4.38e-01 | 83.3% | 86.4% |
| 1owlA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 54.0 | 4.39e-01 | 93.9% | 56.9% |
| 6u3wB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 53.0 | 3.52e-01 | 98.5% | 56.0% |
| 4l7mA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 50.0 | 3.33e-01 | 93.9% | 36.0% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 46.0 | 3.61e-01 | 87.9% | 87.2% |
| 6t0bf00 | 1.25.40.40 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI | 0.58 | 46.0 | 4.03e-01 | 87.9% | 80.4% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.57 | 45.0 | 3.66e-01 | 90.9% | 56.7% |
| 3gt5A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 46.0 | 2.87e-01 | 95.5% | 39.1% |
| 3r0vA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 46.0 | 3.15e-01 | 100.0% | 65.8% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.52 | 43.0 | 4.02e-01 | 100.0% | 73.6% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 36.0 | 3.82e-01 | 83.3% | 92.9% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3507780 | 604.12.1.8 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT | 0.89 | 69.0 | 6.20e-01 | 80.3% | 76.5% |
| 4580956 | 2484.1.1.222 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UPF0236 | 0.84 | 72.0 | 4.81e-01 | 100.0% | 26.0% |
| 3628636 | 109.4.1.631 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP72 | 0.84 | 65.0 | 4.22e-01 | 81.8% | 20.8% |
| 3252144 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.84 | 64.0 | 6.27e-01 | 80.3% | 92.9% |
| 3729025 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.81 | 60.0 | 4.60e-01 | 81.8% | 35.9% |
| 3595737 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.79 | 58.0 | 4.40e-01 | 77.3% | 36.7% |
| 3267491 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.79 | 58.0 | 5.76e-01 | 78.8% | 91.4% |
| 5063675 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.78 | 61.0 | 4.53e-01 | 83.3% | 88.1% |
| 3424566 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.77 | 59.0 | 5.44e-01 | 81.8% | 92.9% |
| 3543543 | 109.59.1.19 ↗ | alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Vps16_N | 0.77 | 59.0 | 5.41e-01 | 81.8% | 88.2% |
| 4660860 | 2484.1.1.222 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UPF0236 | 0.76 | 66.0 | 4.34e-01 | 98.5% | 23.3% |
| 3596138 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.76 | 59.0 | 4.06e-01 | 92.4% | 25.6% |
| 3485316 | 109.7.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E | 0.74 | 55.0 | 5.48e-01 | 80.3% | 80.0% |
| 3876892 | 375.2.1.0 ↗ | few secondary structure elements › Rubredoxin-like › YfgJ-like › YfgJ-like | 0.74 | 54.0 | 5.04e-01 | 87.9% | 62.5% |
| 3741847 | 544.1.1.0 ↗ | alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 | 0.74 | 68.0 | 5.88e-01 | 100.0% | 94.9% |
| 3214310 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 63.0 | 4.74e-01 | 93.9% | 41.9% |
| 3773235 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.72 | 58.0 | 5.25e-01 | 87.9% | 76.7% |
| 3479515 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 55.0 | 4.43e-01 | 81.8% | 77.6% |
| 3586746 | 603.1.1.133 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7799 | 0.70 | 53.0 | 4.43e-01 | 83.3% | 88.3% |
| 5034673 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.70 | 65.0 | 4.85e-01 | 100.0% | 64.7% |
| 3925649 | 3711.1.1.28 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › NPA | 0.69 | 59.0 | 5.00e-01 | 98.5% | 57.3% |
| 3744 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.68 | 53.0 | 4.38e-01 | 87.9% | 73.8% |
| 3450834 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.67 | 56.0 | 4.90e-01 | 89.4% | 71.3% |
| 3782996 | 109.4.1.120 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Kinetochor_Ybp2 | 0.67 | 56.0 | 3.45e-01 | 90.9% | 60.3% |
| 3965561 | 109.4.1.940 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Slam | 0.67 | 59.0 | 4.51e-01 | 100.0% | 98.1% |
| 3506685 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.66 | 53.0 | 5.10e-01 | 87.9% | 85.3% |
| 4032059 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 55.0 | 4.51e-01 | 95.5% | 64.0% |
| 3225046 | 3198.1.1.1 ↗ | alpha bundles › ABA-1 repeat unit › ABA-1 repeat unit › ABA-1 repeat unit › NPA | 0.65 | 55.0 | 4.54e-01 | 100.0% | 50.0% |
| 3225048 | 3198.1.1.1 ↗ | alpha bundles › ABA-1 repeat unit › ABA-1 repeat unit › ABA-1 repeat unit › NPA | 0.65 | 56.0 | 4.62e-01 | 100.0% | 89.6% |
| 3228092 | 3599.1.1.1 ↗ | alpha superhelices › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › MCD_N | 0.64 | 55.0 | 4.34e-01 | 93.9% | 97.8% |
| 3677155 | 109.4.1.570 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps8 | 0.64 | 57.0 | 3.40e-01 | 100.0% | 52.4% |
| 4853300 | 141.1.1.8 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 | 0.63 | 56.0 | 3.88e-01 | 100.0% | 54.1% |
| 3822661 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.63 | 49.0 | 3.63e-01 | 87.9% | 58.9% |
| 3518241 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 53.0 | 3.67e-01 | 95.5% | 29.3% |
| 3976334 | 4995.1.1.3 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › MlrA_helical | 0.61 | 49.0 | 4.52e-01 | 89.4% | 78.8% |
| 4289290 | 109.4.1.207 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 | 0.57 | 48.0 | 3.83e-01 | 92.4% | 57.7% |
| 3355930 | 109.4.1.1495 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26522 | 0.54 | 45.0 | 3.83e-01 | 95.5% | 88.7% |
D2
high
residues 1892-1976
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.83 | 58.0 | 4.62e-01 | 72.9% | 56.6% |
| 6lpfA01 | 1.10.730.20 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › | 0.82 | 58.0 | 4.58e-01 | 72.9% | 58.3% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.82 | 59.0 | 4.33e-01 | 75.3% | 53.6% |
| 1konA01 | 1.10.10.200 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain | 0.80 | 48.0 | 5.29e-01 | 74.1% | 75.0% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.80 | 55.0 | 4.75e-01 | 70.6% | 85.5% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.78 | 53.0 | 4.55e-01 | 70.6% | 76.3% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.77 | 53.0 | 4.89e-01 | 70.6% | 63.2% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.77 | 55.0 | 4.83e-01 | 74.1% | 70.6% |
| 7nmqA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.76 | 53.0 | 3.48e-01 | 72.9% | 75.1% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.75 | 52.0 | 3.96e-01 | 71.8% | 58.1% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.75 | 52.0 | 4.94e-01 | 71.8% | 75.0% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.75 | 52.0 | 4.51e-01 | 71.8% | 72.7% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 51.0 | 4.58e-01 | 71.8% | 86.3% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.72 | 49.0 | 4.35e-01 | 71.8% | 71.2% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.71 | 51.0 | 4.01e-01 | 75.3% | 62.9% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.71 | 50.0 | 5.13e-01 | 72.9% | 92.8% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.71 | 50.0 | 4.51e-01 | 72.9% | 86.3% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.71 | 49.0 | 3.69e-01 | 70.6% | 33.3% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.71 | 49.0 | 4.03e-01 | 71.8% | 58.3% |
| 6axfA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.71 | 48.0 | 4.31e-01 | 70.6% | 56.4% |
| 3bqoA00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.70 | 52.0 | 3.90e-01 | 77.6% | 86.1% |
| 8amzT01 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 49.0 | 3.42e-01 | 72.9% | 44.7% |
| 2wwxB00 | 1.20.1260.70 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 50.0 | 3.71e-01 | 74.1% | 57.5% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 48.0 | 4.31e-01 | 71.8% | 74.6% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 49.0 | 4.14e-01 | 75.3% | 72.7% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.67 | 48.0 | 3.98e-01 | 76.5% | 59.7% |
| 2hr2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 49.0 | 4.02e-01 | 78.8% | 88.5% |
| 2w0gA00 | 1.20.58.610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain | 0.63 | 47.0 | 4.16e-01 | 80.0% | 72.9% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 52.0 | 4.05e-01 | 90.6% | 82.4% |
| 1vpdA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.62 | 44.0 | 3.77e-01 | 74.1% | 89.3% |
| 4jhrB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 52.0 | 3.53e-01 | 90.6% | 84.1% |
| 3hq2B00 | 1.10.1370.30 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › | 0.60 | 51.0 | 3.27e-01 | 100.0% | 61.2% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 53.0 | 4.13e-01 | 98.8% | 84.9% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.59 | 48.0 | 3.77e-01 | 90.6% | 76.9% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.58 | 51.0 | 3.55e-01 | 98.8% | 92.1% |
| 3solA00 | 1.20.58.1630 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS | 0.58 | 43.0 | 4.24e-01 | 80.0% | 76.9% |
| 3wirA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 47.0 | 3.05e-01 | 94.1% | 59.3% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.54 | 37.0 | 3.91e-01 | 76.5% | 82.4% |
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.53 | 41.0 | 4.08e-01 | 85.9% | 92.4% |
| 5lb3B02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 42.0 | 3.15e-01 | 87.1% | 40.4% |
| 3kezA03 | 1.25.40.900 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 39.0 | 3.50e-01 | 78.8% | 74.4% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4936999 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.81 | 57.0 | 4.55e-01 | 72.9% | 57.5% |
| 3386958 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.80 | 56.0 | 4.83e-01 | 71.8% | 67.2% |
| 4139505 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.79 | 55.0 | 4.67e-01 | 71.8% | 66.9% |
| 5013248 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.78 | 54.0 | 4.72e-01 | 71.8% | 68.0% |
| 3971908 | 601.13.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS | 0.78 | 54.0 | 4.71e-01 | 71.8% | 68.0% |
| 3680600 | 604.12.1.67 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › eIF-3c_N | 0.78 | 53.0 | 4.87e-01 | 70.6% | 57.3% |
| 3216492 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.78 | 54.0 | 5.01e-01 | 71.8% | 68.6% |
| 3641586 | 604.12.1.48 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vwaint | 0.77 | 55.0 | 4.92e-01 | 74.1% | 71.3% |
| 3806239 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.77 | 53.0 | 5.70e-01 | 71.8% | 81.3% |
| 3802176 | 604.16.1.3 ↗ | alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint | 0.76 | 54.0 | 5.03e-01 | 74.1% | 78.1% |
| 4066681 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.76 | 52.0 | 4.40e-01 | 70.6% | 86.7% |
| 3171602 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 52.0 | 4.37e-01 | 71.8% | 82.1% |
| 3632454 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.73 | 51.0 | 5.17e-01 | 71.8% | 90.6% |
| 3287061 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.73 | 50.0 | 4.42e-01 | 70.6% | 94.2% |
| 5055056 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.71 | 52.0 | 4.57e-01 | 77.6% | 60.8% |
| 4480629 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.69 | 49.0 | 3.87e-01 | 74.1% | 45.1% |
| 4033699 | 621.1.1.10 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › DUF4118 | 0.69 | 49.0 | 4.27e-01 | 71.8% | 57.6% |
| 3616226 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.69 | 52.0 | 4.60e-01 | 78.8% | 64.2% |
| 4988301 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.68 | 51.0 | 4.29e-01 | 81.2% | 95.3% |
| 3932453 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.66 | 50.0 | 4.48e-01 | 78.8% | 67.0% |
| 3670388 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 50.0 | 4.31e-01 | 81.2% | 52.6% |
| 4935668 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.66 | 45.0 | 3.98e-01 | 71.8% | 90.0% |
| 5063672 | 109.10.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin | 0.66 | 49.0 | 3.85e-01 | 78.8% | 53.6% |
| 3507547 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.66 | 46.0 | 4.91e-01 | 72.9% | 98.6% |
| 4182665 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.66 | 57.0 | 4.56e-01 | 92.9% | 98.8% |
| 5023839 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.65 | 55.0 | 4.13e-01 | 90.6% | 78.0% |
| 4995367 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.65 | 48.0 | 4.22e-01 | 77.6% | 59.2% |
| 3789688 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.65 | 50.0 | 4.36e-01 | 81.2% | 63.2% |
| 3256198 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.64 | 50.0 | 4.30e-01 | 82.4% | 62.3% |
| 5036565 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.64 | 54.0 | 4.15e-01 | 90.6% | 84.3% |
| 3389232 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 58.0 | 3.92e-01 | 100.0% | 60.6% |
| 4979381 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.62 | 53.0 | 4.00e-01 | 94.1% | 77.5% |
| 3914885 | 109.4.1.362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 | 0.62 | 55.0 | 3.33e-01 | 94.1% | 59.2% |
| 4992270 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.62 | 53.0 | 4.18e-01 | 100.0% | 85.6% |
| 3695508 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 53.0 | 3.39e-01 | 94.1% | 76.3% |
| 3603670 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.60 | 51.0 | 3.98e-01 | 100.0% | 79.5% |
| 3652177 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 45.0 | 4.41e-01 | 82.4% | 75.5% |
| 3465154 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 50.0 | 3.30e-01 | 96.5% | 93.9% |
| 4983306 | 610.3.1.1 ↗ | alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain › GatB_Yqey | 0.57 | 40.0 | 3.23e-01 | 75.3% | 35.4% |
| 3183105 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.55 | 47.0 | 3.57e-01 | 100.0% | 85.5% |
| 1259711 | 129.1.1.12 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › DUF1932 | 0.54 | 39.0 | 3.46e-01 | 75.3% | 90.5% |
D3
medium
residues 36-60_86-158
D4
medium
residues 811-891
D5
medium
residues 892-1030
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1lwbA00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.57 | 32.0 | 3.46e-01 | 83.5% | 61.5% |
| 3cz1A00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.53 | 32.0 | 3.48e-01 | 84.2% | 70.1% |
| 2k3nA00 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.52 | 39.0 | 3.79e-01 | 80.6% | 74.4% |
| 2qgsB01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.51 | 31.0 | 3.73e-01 | 78.4% | 95.5% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3244457 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 44.0 | 4.00e-01 | 89.9% | 93.0% |
| 5042736 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.52 | 35.0 | 3.23e-01 | 80.6% | 51.4% |
| 4928304 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 43.0 | 3.16e-01 | 89.9% | 46.4% |
| 4240467 | 1206.1.1.0 ↗ | 0.52 | 35.0 | 3.99e-01 | 84.9% | 95.0% |
D6
medium
residues 1111-1195
D7
medium
residues 1196-1242_1312-1417
D8
medium
residues 1467-1525
D9
medium
residues 1541-1592_1635-1655
D10
medium
residues 1795-1888