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IMGVR_UViG_3300025174_000536-3300025174-Ga0209324_1000070512

Arc-Vir

IMGVR_UViG_3300025174_000536-3300025174-Ga0209324_1000070512

Quality

69.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1859-1910
PDB
D2 medium residues 65-126
PDB
D3 medium residues 736-831
PDB
Domain cluster: representative
D4 medium residues 833-952_1010-1152
PDB
D5 medium residues 953-1009
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.80 52.0 4.87e-01 96.5% 56.7%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 48.0 4.01e-01 94.7% 42.3%
6al9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.68 43.0 3.70e-01 96.5% 40.7%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.66 47.0 3.64e-01 75.4% 86.6%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 45.0 3.45e-01 75.4% 64.6%
2fh0A00 1.10.8.140 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PDCD5, DNA-binding domain 0.64 45.0 3.99e-01 71.9% 71.6%
3llkA01 1.20.120.1960 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › QSOX sulfhydryl oxidase domain 0.64 54.0 4.56e-01 96.5% 79.6%
1blwC00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 52.0 4.04e-01 96.5% 95.0%
4nfnA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 52.0 3.68e-01 98.2% 93.1%
2xubA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 41.0 3.48e-01 100.0% 41.3%
6yetA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.62 51.0 4.38e-01 91.2% 76.9%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.61 42.0 3.38e-01 73.7% 87.1%
6yigA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.61 49.0 4.28e-01 91.2% 79.5%
1m9nA04 3.40.50.1380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain 0.60 53.0 3.67e-01 100.0% 58.9%
1k07A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.60 52.0 3.38e-01 100.0% 48.5%
3hdeC00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.59 52.0 3.79e-01 100.0% 51.8%
4xchA00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.59 49.0 3.61e-01 91.2% 64.4%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.59 43.0 3.77e-01 96.5% 52.9%
1a22A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 52.0 3.66e-01 100.0% 40.0%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 39.0 3.88e-01 96.5% 66.1%
5idmA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.57 47.0 3.42e-01 98.2% 96.0%
4i5jA02 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.56 43.0 3.33e-01 91.2% 90.4%
3nlcA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 48.0 3.17e-01 98.2% 90.9%
4ua8A02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.54 43.0 3.06e-01 91.2% 76.2%
1i24A02 3.90.25.10 Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 0.54 47.0 3.53e-01 98.2% 40.8%
1tx9A00 1.10.1850.10 Mainly Alpha › Orthogonal Bundle › Procapsid Of Bacteriophage Phix174, Chain 1 › Scaffold protein D 0.52 45.0 3.44e-01 100.0% 69.5%
2gqtA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.52 43.0 3.51e-01 100.0% 90.9%
1pujA02 1.10.1580.10 Mainly Alpha › Orthogonal Bundle › Conserved Hypothetical Protein Ylqf; Chain: A; domain 2 › 0.51 41.0 3.59e-01 93.0% 62.4%
3pvlA03 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.50 45.0 3.52e-01 98.2% 65.3%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.50 34.0 3.04e-01 71.9% 78.2%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3568558 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.75 58.0 5.80e-01 98.2% 81.7%
4932398 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.70 60.0 5.30e-01 98.2% 96.5%
54722 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.70 57.0 4.96e-01 96.5% 90.4%
3570202 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.68 59.0 4.89e-01 96.5% 83.0%
None 0.68 47.0 3.09e-01 77.2% 17.4%
5056440 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.67 57.0 3.80e-01 100.0% 78.8%
3248244 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.64 56.0 5.29e-01 100.0% 91.4%
3962880 2003.1.2.69 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_8, Pyr_redox_3 0.63 52.0 3.58e-01 96.5% 40.0%
5077474 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.62 50.0 4.27e-01 96.5% 69.5%
3837701 101.1.17.2 alpha arrays › HTH › HTH › FF domain › FF 0.59 42.0 4.06e-01 96.5% 66.2%
4947397 3896.1.1.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase 0.59 50.0 3.47e-01 100.0% 73.5%
4975282 545.1.2.0 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain 0.59 41.0 3.68e-01 96.5% 52.5%
4941082 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.58 44.0 3.54e-01 89.5% 42.6%
2796011 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 38.0 3.16e-01 98.2% 37.0%
3627539 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.57 51.0 4.37e-01 100.0% 97.8%
3786380 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.57 46.0 2.95e-01 91.2% 83.8%
3730038 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.56 39.0 3.02e-01 75.4% 62.1%
4993069 632.12.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Vng1086c-like › Vng1086c-like › UPF0058 0.55 38.0 3.78e-01 73.7% 100.0%
3993081 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 46.0 3.46e-01 100.0% 91.9%
3993353 109.4.1.1644 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HDS, BIG2_C 0.54 48.0 2.70e-01 98.2% 13.1%
4369324 101.1.1.142 alpha arrays › HTH › HTH › Three-helical HTH › clamp_Gag1-like 0.54 36.0 3.73e-01 70.2% 94.5%
4975919 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.53 45.0 2.94e-01 96.5% 70.0%
3635475 148.1.3.113 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_TRIP13_C 0.52 35.0 2.88e-01 71.9% 83.2%
3354956 4.1.1.12 beta barrels › SH3 › SH3 › SH3 › PWWP 0.52 39.0 2.69e-01 80.7% 51.4%
3875706 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.51 45.0 3.28e-01 98.2% 47.7%
4030617 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.51 41.0 3.94e-01 96.5% 75.7%
3967708 179.1.1.1 alpha bundles › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like › Fer2_2 0.50 41.0 3.47e-01 87.7% 55.6%
D6 medium residues 1372-1489
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4oogC01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.53 38.0 3.48e-01 75.4% 66.7%
3dxlA02 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.51 38.0 3.55e-01 78.8% 91.4%
2x1dA02 1.10.10.2120 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.51 30.0 3.66e-01 75.4% 93.2%
4ezbA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.50 34.0 3.51e-01 97.5% 70.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3271988 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.65 30.0 3.82e-01 74.6% 71.2%
3431353 1128.1.1.10 alpha bundles › LYR protein › LYR protein › LYR protein › VIN3_C 0.63 30.0 3.88e-01 71.2% 78.6%
3847579 206.1.1.118 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › UBA_SIK3 0.62 33.0 4.32e-01 88.1% 100.0%
4427540 171.1.1.1 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.56 39.0 3.28e-01 71.2% 84.9%
4965108 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.52 40.0 3.07e-01 99.2% 35.3%
D7 medium residues 1490-1539
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2iiuA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.91 71.0 4.56e-01 84.0% 21.2%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.84 64.0 5.31e-01 84.0% 51.7%
3hpcX00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.82 62.0 4.30e-01 84.0% 26.5%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.76 67.0 4.85e-01 98.0% 68.4%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 58.0 5.63e-01 90.0% 75.4%
2xkoC02 6.10.250.870 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.73 50.0 5.49e-01 74.0% 100.0%
4djgB00 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.71 57.0 5.91e-01 90.0% 100.0%
4izbB02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.70 51.0 5.40e-01 80.0% 93.0%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.69 54.0 5.19e-01 90.0% 76.7%
1yzmA00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.68 50.0 5.18e-01 80.0% 91.3%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.68 51.0 5.11e-01 84.0% 84.3%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.67 57.0 4.25e-01 98.0% 41.0%
5tw1D01 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.67 48.0 3.48e-01 78.0% 94.5%
1z5zA02 1.20.120.850 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain 0.66 57.0 5.02e-01 100.0% 93.4%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 57.0 4.93e-01 100.0% 82.1%
2jaeA03 1.20.1440.240 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.63 53.0 4.30e-01 100.0% 48.5%
3nowA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 52.0 3.20e-01 100.0% 14.2%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.62 51.0 4.97e-01 96.0% 87.7%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 53.0 4.71e-01 98.0% 67.1%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 51.0 4.76e-01 98.0% 76.6%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.59 47.0 4.07e-01 98.0% 54.1%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4943264 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.85 62.0 5.37e-01 78.0% 54.7%
3638386 603.1.1.111 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TBCC_N 0.84 65.0 5.04e-01 84.0% 42.9%
3491875 4146.1.1.0 alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like 0.83 61.0 5.78e-01 80.0% 71.7%
3465357 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 63.0 4.81e-01 84.0% 38.3%
3669330 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.77 60.0 5.05e-01 86.0% 52.9%
3952510 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.76 60.0 5.24e-01 86.0% 61.3%
3853508 5.1.4.401 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › TLE_N 0.73 56.0 5.05e-01 84.0% 61.4%
3245826 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.69 56.0 3.70e-01 92.0% 36.2%
4293733 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.63 56.0 4.36e-01 100.0% 51.4%
D8 medium residues 1540-1617
PDB