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IMGVR_UViG_3300025174_000542-3300025174-Ga0209324_100072119

Arc-Vir

IMGVR_UViG_3300025174_000542-3300025174-Ga0209324_100072119

Quality

56.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 159-181_312-383
PDB
Domain cluster: representative
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.71 63.0 5.41e-01 100.0% 72.5%
4d0nB01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.67 59.0 4.44e-01 100.0% 73.1%
7e4gA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 59.0 4.68e-01 100.0% 57.4%
5tj5E00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.65 50.0 4.44e-01 82.1% 74.6%
7oq4Z01 1.20.120.950 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 0.63 49.0 4.85e-01 82.1% 86.7%
2vsgA02 1.10.470.10 Mainly Alpha › Orthogonal Bundle › Variant Surface Glycoprotein, subunit A; domain 2 › Variant Surface Glycoprotein, subunit A, domain 2 0.62 50.0 4.21e-01 86.3% 75.6%
1c3cA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.62 42.0 4.46e-01 86.3% 81.5%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.62 41.0 4.65e-01 80.0% 90.3%
4yozA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.62 51.0 4.20e-01 92.6% 64.4%
3vr4B04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.62 43.0 3.74e-01 73.7% 55.0%
3vkgA09 1.20.920.30 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.61 54.0 4.75e-01 98.9% 68.8%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.61 53.0 4.73e-01 100.0% 75.2%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.61 52.0 4.45e-01 94.7% 80.5%
2ffjA01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.60 36.0 4.35e-01 73.7% 100.0%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.59 41.0 4.41e-01 71.6% 96.1%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.59 48.0 4.73e-01 91.6% 90.3%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.58 48.0 4.68e-01 91.6% 79.0%
4dmbB00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.58 42.0 3.38e-01 75.8% 85.3%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.58 39.0 4.50e-01 84.2% 100.0%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 42.0 4.15e-01 76.8% 87.9%
2wteA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 31.0 3.45e-01 87.4% 66.7%
3q1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.57 46.0 4.18e-01 92.6% 97.1%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 48.0 4.76e-01 95.8% 98.0%
4cxfA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.57 41.0 4.24e-01 75.8% 100.0%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.56 41.0 3.48e-01 75.8% 57.4%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.56 51.0 4.39e-01 100.0% 71.2%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.56 43.0 4.27e-01 100.0% 78.6%
2gslF00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.56 40.0 3.71e-01 76.8% 96.1%
1n1fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 49.0 4.23e-01 100.0% 66.0%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 42.0 4.19e-01 92.6% 81.4%
2epgB00 3.90.1860.10 Alpha Beta › Alpha-Beta Complex › tRNA-splicing ligase RtcB › tRNA-splicing ligase RtcB 0.54 45.0 2.98e-01 93.7% 72.9%
3aq1B02 3.30.260.10 Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain 0.54 44.0 4.25e-01 89.5% 95.5%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 43.0 3.88e-01 89.5% 73.2%
3natA01 3.40.50.11250 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF3013 0.54 38.0 3.37e-01 75.8% 61.9%
1jswA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.54 44.0 3.90e-01 89.5% 71.5%
2k3oA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.53 44.0 4.03e-01 92.6% 69.8%
4nqwA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 37.0 3.87e-01 71.6% 98.8%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.53 37.0 3.98e-01 73.7% 92.6%
1lk3A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 44.0 3.94e-01 91.6% 68.4%
6ks6B02 3.30.260.10 Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain 0.52 44.0 4.13e-01 95.8% 100.0%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 37.0 3.13e-01 72.6% 44.3%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.52 36.0 3.76e-01 72.6% 83.0%
1yfmA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.52 43.0 3.94e-01 91.6% 70.6%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.51 38.0 3.86e-01 84.2% 80.4%
1t3dA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.51 42.0 3.82e-01 95.8% 84.3%
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.51 37.0 3.71e-01 75.8% 94.7%
4v2kA01 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.51 42.0 3.81e-01 93.7% 94.0%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.50 35.0 3.65e-01 73.7% 91.0%
1v4aA03 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.50 37.0 3.19e-01 77.9% 69.3%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3604441 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 56.0 4.65e-01 94.7% 53.5%
4977418 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.65 57.0 5.50e-01 98.9% 98.2%
5077807 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.65 46.0 5.23e-01 80.0% 100.0%
4985470 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.62 43.0 4.80e-01 85.3% 97.1%
4946843 4009.1.1.1 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.62 41.0 4.74e-01 75.8% 100.0%
3058754 3819.1.1.0 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.61 54.0 3.63e-01 98.9% 45.6%
4337796 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.61 46.0 3.98e-01 80.0% 64.0%
3719175 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.61 53.0 4.56e-01 100.0% 80.6%
5031190 4952.1.1.0 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like 0.60 48.0 4.65e-01 91.6% 76.2%
5082367 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.60 40.0 4.64e-01 74.7% 100.0%
5034808 4009.1.1.1 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.60 41.0 4.61e-01 85.3% 97.1%
4951777 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.59 51.0 3.51e-01 96.8% 27.3%
4547823 150.1.1.57 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › NEPRO_N 0.59 51.0 3.99e-01 100.0% 68.7%
4947265 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.59 41.0 4.57e-01 84.2% 97.1%
4537668 1134.1.1.8 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › Use1 0.59 42.0 4.69e-01 74.7% 100.0%
2875500 601.4.1.4 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PilJ 0.59 41.0 3.70e-01 72.6% 66.7%
5001051 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.59 37.0 4.40e-01 82.1% 100.0%
4976851 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.59 41.0 4.59e-01 85.3% 98.6%
4946850 604.39.1.1 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › CbiM 0.59 49.0 3.73e-01 90.5% 54.7%
5071361 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.59 44.0 4.80e-01 80.0% 100.0%
4931700 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.59 41.0 4.65e-01 86.3% 100.0%
5003875 4009.1.1.1 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.58 39.0 4.45e-01 86.3% 100.0%
5025553 4952.1.1.0 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like 0.58 45.0 4.51e-01 91.6% 79.0%
3560659 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 50.0 3.58e-01 98.9% 82.8%
3415904 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.58 48.0 4.90e-01 92.6% 100.0%
3388163 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.58 41.0 2.87e-01 74.7% 68.5%
4977335 604.12.1.139 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF1844 0.58 41.0 4.30e-01 73.7% 97.6%
4992927 4009.1.1.1 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.57 39.0 4.41e-01 85.3% 97.1%
3709689 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.57 50.0 4.35e-01 100.0% 65.3%
3743981 5081.1.1.2 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 0.56 46.0 3.79e-01 92.6% 92.6%
5031953 2498.5.1.1 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like › Cpn60_TCP1 0.56 45.0 4.27e-01 87.4% 88.7%
3280503 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 46.0 3.33e-01 89.5% 70.2%
5035764 2498.5.1.0 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like 0.55 45.0 4.30e-01 87.4% 93.6%
3889356 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.55 48.0 3.65e-01 100.0% 60.1%
5073879 2498.5.1.1 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like › Cpn60_TCP1 0.55 46.0 4.54e-01 94.7% 98.1%
3389275 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.54 32.0 3.35e-01 100.0% 62.2%
4932576 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.54 44.0 3.58e-01 91.6% 55.0%
3990747 2498.5.1.0 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like 0.54 43.0 4.14e-01 86.3% 89.1%
4946911 2498.5.1.1 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like › Cpn60_TCP1 0.54 46.0 4.45e-01 94.7% 97.1%
4325828 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 34.0 2.86e-01 70.5% 35.3%
3967936 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.53 37.0 4.04e-01 72.6% 94.7%
4948289 2487.1.1.1 a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › Cpn60_TCP1 0.53 41.0 3.19e-01 85.3% 94.8%
3257636 610.2.1.0 alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 0.53 39.0 3.74e-01 80.0% 69.6%
4025225 5051.1.1.7 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp 0.53 46.0 3.00e-01 100.0% 77.8%
4196260 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.53 37.0 3.73e-01 73.7% 76.0%
3171253 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.52 46.0 2.90e-01 100.0% 58.0%
139995 321.1.1.8 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Glu_cys_ligase 0.52 40.0 2.59e-01 84.2% 49.0%
3187418 601.1.2.149 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30922 0.52 46.0 4.39e-01 100.0% 97.4%
5076836 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.51 39.0 2.56e-01 89.5% 16.3%
5007377 633.6.1.3 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB 0.51 44.0 3.67e-01 97.9% 99.4%
5036454 3896.1.2.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase 0.51 40.0 3.77e-01 85.3% 78.3%
4015375 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 35.0 2.70e-01 72.6% 30.2%
D2 medium residues 182-311
PDB
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.73 35.0 4.48e-01 86.2% 77.6%
2z0qA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.73 60.0 5.23e-01 87.7% 80.8%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 32.0 4.23e-01 86.2% 77.0%
3ezhA00 1.20.120.960 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain 0.70 40.0 4.26e-01 93.1% 64.0%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 50.0 4.16e-01 73.8% 93.7%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 5.43e-01 81.5% 95.8%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.69 55.0 4.71e-01 86.2% 79.2%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 39.0 4.48e-01 90.0% 76.5%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 54.0 4.61e-01 86.2% 61.3%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.66 47.0 4.88e-01 72.3% 95.8%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 51.0 5.37e-01 80.8% 94.8%
3v5uA02 1.20.1420.30 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › NCX, central ion-binding region 0.66 48.0 4.02e-01 75.4% 62.4%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.66 34.0 4.10e-01 83.8% 74.7%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 52.0 4.94e-01 84.6% 77.3%
2qwoB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.65 39.0 4.49e-01 73.8% 82.6%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 43.0 3.68e-01 70.0% 76.6%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.63 42.0 4.45e-01 70.0% 77.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 45.0 5.02e-01 88.5% 100.0%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.61 45.0 4.99e-01 86.2% 100.0%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 42.0 3.75e-01 70.8% 77.2%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 38.0 3.71e-01 96.9% 56.6%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 44.0 4.86e-01 86.9% 100.0%
3f7cA00 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.60 52.0 4.54e-01 96.2% 91.5%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.59 34.0 4.33e-01 84.6% 97.4%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.59 45.0 4.85e-01 81.5% 100.0%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.59 43.0 4.05e-01 76.9% 80.7%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 35.0 3.22e-01 83.1% 47.2%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 43.0 3.78e-01 76.9% 90.6%
5n17A01 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.58 41.0 4.48e-01 73.1% 99.0%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 45.0 4.29e-01 81.5% 74.0%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 37.0 3.63e-01 98.5% 59.4%
3k1zA02 1.10.150.720 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Haloacid dehalogenase-like hydrolase 0.56 27.0 3.22e-01 81.5% 65.5%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.56 41.0 3.84e-01 76.2% 92.0%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 44.0 3.56e-01 83.8% 73.8%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.56 38.0 3.66e-01 70.8% 71.0%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 45.0 3.86e-01 90.0% 86.4%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 46.0 4.37e-01 91.5% 86.5%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 45.0 4.32e-01 89.2% 92.6%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 46.0 4.42e-01 93.1% 86.2%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 46.0 4.49e-01 92.3% 92.9%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 45.0 4.28e-01 91.5% 85.8%
5b2nA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 45.0 3.66e-01 93.8% 85.6%
8ipqB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 39.0 3.06e-01 77.7% 56.6%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 42.0 3.96e-01 87.7% 71.4%
4jbeB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 46.0 3.66e-01 100.0% 58.1%
2cwyA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.51 33.0 3.76e-01 82.3% 89.2%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.51 38.0 3.68e-01 77.7% 80.5%
2c2jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 42.0 3.93e-01 90.8% 70.3%
2nxpB00 1.25.40.500 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain 0.51 38.0 3.70e-01 77.7% 94.5%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 43.0 4.07e-01 93.1% 85.1%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3440858 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.75 57.0 5.65e-01 79.2% 88.9%
3737997 4146.1.1.14 alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like › Sec5 0.73 52.0 5.52e-01 73.1% 95.7%
3399861 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 56.0 5.56e-01 83.1% 91.1%
3383516 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.69 53.0 5.38e-01 81.5% 92.3%
3310861 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.68 55.0 3.91e-01 87.7% 66.8%
5035939 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 55.0 5.38e-01 89.2% 82.1%
3707921 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.66 52.0 5.55e-01 83.1% 100.0%
3466334 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 51.0 5.11e-01 85.4% 89.2%
3705915 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.60 48.0 5.04e-01 86.2% 92.5%
3203851 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 42.0 3.88e-01 93.1% 57.0%
3288766 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.60 47.0 4.67e-01 82.3% 97.0%
3838087 3799.1.1.0 alpha bundles › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain 0.59 47.0 4.02e-01 86.2% 83.2%
5026129 5051.1.1.2 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease 0.59 47.0 3.23e-01 84.6% 81.4%
3951884 109.4.1.497 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EccD 0.59 43.0 3.23e-01 76.2% 47.9%
5076790 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.59 46.0 3.39e-01 82.3% 58.5%
5026525 633.7.1.0 alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like 0.58 41.0 4.73e-01 73.1% 96.9%
4992414 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.58 47.0 4.39e-01 83.8% 78.7%
4671917 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.58 34.0 3.60e-01 88.5% 64.3%
3408441 633.10.1.30 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › DUF7027 0.58 44.0 4.53e-01 80.0% 94.2%
4978123 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.58 43.0 3.28e-01 78.5% 50.6%
4940116 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.57 45.0 4.40e-01 83.1% 82.1%
3972733 5050.1.1.22 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like 0.57 42.0 3.75e-01 77.7% 94.2%
3207738 4244.1.1.2 a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like › Erythro_esteras 0.57 45.0 3.17e-01 85.4% 27.2%
4944553 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.56 40.0 3.15e-01 74.6% 59.7%
5044882 140.1.1.7 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.56 44.0 3.74e-01 83.8% 60.1%
3869951 611.2.1.0 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) 0.55 40.0 4.30e-01 90.8% 85.2%
5033828 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.55 47.0 3.21e-01 90.8% 41.8%
223656 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.55 47.0 4.39e-01 91.5% 84.8%
3925884 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.54 49.0 3.35e-01 99.2% 64.6%
4982139 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.54 45.0 4.29e-01 89.2% 86.7%
3572352 1188.1.1.1 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip 0.54 43.0 3.50e-01 85.4% 52.8%
5038534 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.53 43.0 4.23e-01 90.0% 89.7%
3801452 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.53 45.0 4.26e-01 93.1% 86.5%
3940557 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.52 42.0 4.21e-01 83.8% 93.8%
3699295 5086.1.1.158 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Sec5 0.52 37.0 3.78e-01 74.6% 94.6%
3979925 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 38.0 3.39e-01 77.7% 82.6%
3282932 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.51 43.0 4.18e-01 92.3% 88.3%
4062922 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.51 46.0 4.59e-01 100.0% 94.1%
3944579 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 39.0 3.39e-01 80.8% 85.0%
4470940 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.50 40.0 2.99e-01 85.4% 94.3%
3535922 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.50 43.0 4.06e-01 92.3% 89.7%
D3 medium residues 428-478
PDB