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IMGVR_UViG_3300025314_000686-3300025314-Ga0209323_100063281
Arc-VirIMGVR_UViG_3300025314_000686-3300025314-Ga0209323_100063281
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 91-142
Domain cluster:
representative
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5lbmA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.76 | 63.0 | 5.47e-01 | 96.2% | 86.7% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 60.0 | 5.31e-01 | 92.3% | 100.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 62.0 | 5.86e-01 | 98.1% | 84.6% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 60.0 | 4.11e-01 | 96.2% | 43.0% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 51.0 | 4.34e-01 | 76.9% | 50.0% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 58.0 | 4.47e-01 | 92.3% | 74.4% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.68 | 54.0 | 4.10e-01 | 86.5% | 40.0% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 56.0 | 5.19e-01 | 98.1% | 80.6% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.67 | 54.0 | 4.94e-01 | 94.2% | 90.5% |
| 3u62A01 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.67 | 42.0 | 3.22e-01 | 82.7% | 26.4% |
| 2kwhA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 50.0 | 4.92e-01 | 84.6% | 96.4% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.67 | 55.0 | 4.13e-01 | 96.2% | 39.2% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 4.46e-01 | 96.2% | 54.3% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 54.0 | 4.52e-01 | 96.2% | 54.5% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.66 | 57.0 | 4.27e-01 | 94.2% | 77.4% |
| 1p49A02 | 1.10.287.550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 52.0 | 5.09e-01 | 96.2% | 86.4% |
| 3crvA02 | 1.10.275.30 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › | 0.65 | 50.0 | 4.01e-01 | 84.6% | 40.7% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.65 | 52.0 | 4.43e-01 | 100.0% | 62.4% |
| 1ny9A00 | 1.10.490.50 | Mainly Alpha › Orthogonal Bundle › Globin-like › Antibiotic binding domain of TipA-like multidrug resistance regulators | 0.64 | 49.0 | 4.12e-01 | 86.5% | 47.9% |
| 2l37A00 | 6.10.250.890 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 45.0 | 4.74e-01 | 96.2% | 95.3% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 50.0 | 3.37e-01 | 96.2% | 22.5% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 52.0 | 3.96e-01 | 98.1% | 38.8% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 52.0 | 4.91e-01 | 98.1% | 78.5% |
| 1bm9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 48.0 | 3.71e-01 | 86.5% | 92.5% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.61 | 45.0 | 4.55e-01 | 86.5% | 88.0% |
| 3q18A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 47.0 | 3.77e-01 | 90.4% | 41.4% |
| 1ym3A00 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.59 | 46.0 | 3.14e-01 | 86.5% | 25.9% |
| 3f2bA05 | 6.10.50.10 | Special › Helix non-globular › Insulin-like, subunit E › | 0.58 | 39.0 | 4.06e-01 | 76.9% | 70.8% |
| 5h20A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.57 | 45.0 | 3.68e-01 | 88.5% | 97.1% |
| 1w36B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 49.0 | 3.18e-01 | 98.1% | 64.5% |
| 2ds2D01 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.57 | 46.0 | 4.49e-01 | 98.1% | 82.5% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.56 | 46.0 | 4.18e-01 | 98.1% | 72.0% |
| 1knzA01 | 6.10.280.20 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rotavirus non-structural protein NSP3, N-terminal domain | 0.56 | 48.0 | 3.92e-01 | 100.0% | 52.0% |
| 1ak2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 40.0 | 2.75e-01 | 92.3% | 86.8% |
| 3cbuA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 41.0 | 3.17e-01 | 96.2% | 43.3% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.50 | 44.0 | 4.07e-01 | 100.0% | 97.1% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1790834 | 3086.1.1.1 ↗ | alpha bundles › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › DAGK_prokar | 0.77 | 65.0 | 5.60e-01 | 96.2% | 63.1% |
| 3605439 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.75 | 58.0 | 5.30e-01 | 84.6% | 67.1% |
| 3198009 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.75 | 58.0 | 4.91e-01 | 84.6% | 56.5% |
| 3275809 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.75 | 59.0 | 3.57e-01 | 86.5% | 14.8% |
| 3260684 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.74 | 55.0 | 5.44e-01 | 78.8% | 74.5% |
| 3975557 | 3782.1.1.0 ↗ | a+b duplicates or obligate multimers › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related | 0.73 | 62.0 | 5.85e-01 | 98.1% | 98.5% |
| 3697800 | 3559.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 | 0.73 | 62.0 | 4.79e-01 | 94.2% | 78.3% |
| 4209288 | 4336.1.1.1 ↗ | alpha duplicates or obligate multimers › YheA/YmcA-like › YheA/YmcA-like › YheA/YmcA-like › Com_YlbF | 0.73 | 59.0 | 4.47e-01 | 86.5% | 40.0% |
| 4234968 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.73 | 58.0 | 4.30e-01 | 86.5% | 35.4% |
| 3614837 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 58.0 | 3.73e-01 | 90.4% | 19.6% |
| 4493879 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.73 | 61.0 | 4.75e-01 | 92.3% | 47.3% |
| 3725506 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 62.0 | 4.82e-01 | 94.2% | 85.5% |
| 3497418 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 58.0 | 4.63e-01 | 86.5% | 49.0% |
| 3179180 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.72 | 58.0 | 3.89e-01 | 86.5% | 24.9% |
| 5004067 | 192.3.1.1 ↗ | alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N | 0.72 | 57.0 | 4.85e-01 | 86.5% | 55.3% |
| 3445025 | 174.1.1.2 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal | 0.72 | 62.0 | 4.43e-01 | 98.1% | 79.4% |
| 4018255 | 2004.1.1.250 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd | 0.71 | 57.0 | 3.22e-01 | 86.5% | 8.5% |
| 4396754 | 4336.1.1.1 ↗ | alpha duplicates or obligate multimers › YheA/YmcA-like › YheA/YmcA-like › YheA/YmcA-like › Com_YlbF | 0.71 | 57.0 | 4.36e-01 | 86.5% | 41.7% |
| 3400028 | 3843.1.1.30 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF4781 | 0.70 | 55.0 | 4.71e-01 | 86.5% | 89.4% |
| 3354385 | 3755.1.1.22 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › DUF3475 | 0.69 | 61.0 | 4.01e-01 | 96.2% | 27.8% |
| 3936188 | 109.4.1.32 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G | 0.69 | 55.0 | 3.12e-01 | 86.5% | 9.2% |
| 3587855 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.69 | 55.0 | 5.67e-01 | 88.5% | 100.0% |
| 3204414 | 1.1.17.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 | 0.68 | 57.0 | 3.43e-01 | 92.3% | 13.9% |
| 3287986 | 605.8.1.7 ↗ | alpha duplicates or obligate multimers › ROP-like › BAS1536-like › BAS1536-like › DUF6374 | 0.68 | 54.0 | 5.53e-01 | 86.5% | 96.0% |
| 4177674 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.68 | 55.0 | 4.32e-01 | 90.4% | 46.4% |
| 3840952 | 601.19.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C | 0.67 | 55.0 | 4.90e-01 | 92.3% | 68.0% |
| 3428029 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.67 | 56.0 | 4.59e-01 | 96.2% | 84.0% |
| 4025 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.66 | 54.0 | 4.52e-01 | 96.2% | 54.5% |
| 3754639 | 150.5.1.106 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › LIN9_C | 0.66 | 53.0 | 4.55e-01 | 90.4% | 60.0% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.65 | 55.0 | 4.53e-01 | 92.3% | 53.7% |
| 2485668 | 7025.1.1.2 ↗ | alpha bundles › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9_C | 0.65 | 52.0 | 4.50e-01 | 90.4% | 58.3% |
| 4942772 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.64 | 54.0 | 5.06e-01 | 96.2% | 80.0% |
| 3997366 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.64 | 53.0 | 3.47e-01 | 98.1% | 22.0% |
| 3899274 | 109.4.1.108 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CTNNBL | 0.61 | 50.0 | 2.90e-01 | 94.2% | 9.3% |
| 5001607 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.61 | 48.0 | 3.77e-01 | 96.2% | 37.0% |
| 4258627 | 2004.1.1.53 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt | 0.56 | 46.0 | 2.75e-01 | 100.0% | 11.5% |