Back to structures

IMGVR_UViG_3300025322_000015-3300025322-Ga0209641_1000006482

Arc-Vir

IMGVR_UViG_3300025322_000015-3300025322-Ga0209641_1000006482

Quality

77.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-81
PDB
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.74 61.0 5.94e-01 98.7% 81.2%
1k32A03 3.30.750.44 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.69 50.0 5.10e-01 92.0% 79.2%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.69 56.0 5.12e-01 98.7% 66.0%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.68 44.0 4.99e-01 72.0% 87.7%
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.68 57.0 5.33e-01 94.7% 74.7%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 60.0 4.33e-01 100.0% 95.8%
1g3nC01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.67 52.0 4.45e-01 97.3% 51.7%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.67 55.0 5.28e-01 97.3% 78.4%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.66 54.0 5.38e-01 94.7% 86.8%
6ldiF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 57.0 5.30e-01 97.3% 86.5%
3mhsB00 1.10.246.140 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 0.65 43.0 4.05e-01 85.3% 54.9%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.65 56.0 5.24e-01 98.7% 83.2%
1ekjA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.64 54.0 3.92e-01 93.3% 62.4%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.64 55.0 5.01e-01 98.7% 87.4%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 48.0 4.84e-01 89.3% 82.7%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.62 54.0 5.49e-01 100.0% 100.0%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.61 54.0 4.63e-01 98.7% 86.8%
3h2zA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.61 44.0 3.38e-01 78.7% 32.4%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.61 43.0 4.26e-01 73.3% 71.8%
1wvuB02 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.61 50.0 3.70e-01 100.0% 34.7%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.60 43.0 4.64e-01 76.0% 92.3%
3k2jA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 44.0 3.78e-01 77.3% 95.0%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 51.0 3.85e-01 96.0% 67.6%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 45.0 3.75e-01 84.0% 75.9%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 39.0 3.47e-01 72.0% 47.2%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.59 43.0 3.92e-01 77.3% 66.7%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 46.0 3.67e-01 84.0% 89.5%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.59 39.0 4.07e-01 74.7% 76.1%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.56 48.0 4.76e-01 100.0% 96.1%
1s7bA00 1.10.3730.20 Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › 0.56 45.0 4.11e-01 92.0% 66.0%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 48.0 4.01e-01 98.7% 64.9%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 39.0 3.11e-01 73.3% 48.9%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 48.0 4.08e-01 98.7% 70.8%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.54 48.0 3.59e-01 98.7% 88.6%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.53 39.0 3.99e-01 76.0% 87.3%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.52 38.0 3.07e-01 77.3% 61.5%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.52 37.0 3.48e-01 73.3% 80.0%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.52 46.0 3.63e-01 98.7% 58.4%
2e9fB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.51 41.0 3.87e-01 94.7% 71.9%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.51 37.0 3.69e-01 76.0% 74.7%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 3.36e-01 76.0% 82.4%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.51 35.0 3.66e-01 77.3% 76.1%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.51 45.0 3.95e-01 100.0% 69.0%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.51 42.0 4.07e-01 93.3% 87.4%
2igsA00 1.10.3690.10 Mainly Alpha › Orthogonal Bundle › PA2222-like fold › PA2222-like domain 0.50 44.0 3.23e-01 100.0% 98.1%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4272325 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.75 61.0 4.40e-01 100.0% 31.9%
4983608 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.72 51.0 5.41e-01 74.7% 90.8%
3177803 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.71 55.0 5.09e-01 94.7% 66.3%
3997160 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.70 62.0 5.68e-01 100.0% 78.0%
4876272 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.70 55.0 5.14e-01 100.0% 68.0%
3709879 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.70 58.0 5.83e-01 97.3% 92.0%
4050460 5045.1.1.1 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.70 60.0 4.44e-01 96.0% 77.5%
4524644 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.70 56.0 4.11e-01 100.0% 32.7%
None 0.69 55.0 4.02e-01 100.0% 30.9%
4999592 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.67 52.0 5.27e-01 86.7% 86.7%
3032802 152.1.1.1 alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RPB6 › RNA_pol_Rpb6 0.67 48.0 5.27e-01 88.0% 96.6%
4273807 314.1.1.0 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.67 50.0 3.11e-01 81.3% 61.6%
3389526 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.66 59.0 5.40e-01 100.0% 79.0%
5071361 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.66 53.0 5.35e-01 97.3% 90.7%
3494175 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.65 56.0 4.10e-01 100.0% 41.4%
4625344 152.1.2.0 alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit 0.64 48.0 4.93e-01 89.3% 84.3%
3673248 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 47.0 4.68e-01 80.0% 75.0%
4250162 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.64 41.0 3.33e-01 74.7% 36.3%
3931278 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 45.0 4.00e-01 74.7% 86.1%
3593164 524.1.1.0 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p 0.62 52.0 4.11e-01 94.7% 63.6%
4994573 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.62 43.0 4.22e-01 72.0% 70.0%
2741727 101.1.10.14 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C_2 0.61 45.0 4.57e-01 89.3% 81.6%
3412881 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.60 53.0 5.21e-01 100.0% 98.8%
3784055 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.60 43.0 3.60e-01 76.0% 45.4%
4324922 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.59 41.0 3.98e-01 76.0% 63.5%
5044960 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 50.0 4.94e-01 100.0% 90.0%
4034571 632.19.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.59 47.0 4.78e-01 98.7% 92.0%
3995514 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.58 40.0 3.28e-01 70.7% 77.9%
5040031 632.22.1.199 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PLDc_N 0.56 46.0 4.56e-01 100.0% 91.8%
5008556 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.56 48.0 4.66e-01 100.0% 83.5%
3934670 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 46.0 3.58e-01 94.7% 78.3%
3383340 3711.1.1.4 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 0.54 48.0 3.86e-01 98.7% 73.1%
3600869 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.54 38.0 3.33e-01 74.7% 52.2%
3471803 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.52 46.0 3.92e-01 100.0% 84.0%
5065764 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.51 46.0 4.09e-01 98.7% 79.0%
3786967 604.13.1.0 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.51 37.0 3.40e-01 84.0% 57.1%
4955309 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.50 43.0 4.24e-01 96.0% 97.5%
D2 high residues 124-200
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2o3fA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 54.0 5.36e-01 97.4% 69.5%
3iwfB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 52.0 4.94e-01 97.4% 66.3%
4ivnA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 51.0 5.18e-01 97.4% 77.6%
5fgmA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 49.0 5.27e-01 100.0% 92.3%
3vfzB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 46.0 4.91e-01 96.1% 88.9%
3hugA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 46.0 4.60e-01 97.4% 75.0%
3l0iA01 1.20.120.1520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 41.0 3.27e-01 100.0% 38.6%
1on2A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 40.0 4.14e-01 83.1% 88.9%
2e1mA05 1.10.405.10 Mainly Alpha › Orthogonal Bundle › Guanine Nucleotide Dissociation Inhibitor; domain 1 › Guanine Nucleotide Dissociation Inhibitor, domain 1 0.51 36.0 3.44e-01 74.0% 80.2%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4008194 101.1.1.11 alpha arrays › HTH › HTH › Three-helical HTH › HTH_6 0.76 54.0 5.49e-01 97.4% 76.0%
3979850 101.1.1.11 alpha arrays › HTH › HTH › Three-helical HTH › HTH_6 0.75 53.0 5.12e-01 96.1% 67.1%
3454663 131.2.1.0 alpha complex topology › PDEase-like › Poly A polymerase C-terminal region-like › Poly A polymerase C-terminal region-like 0.61 53.0 3.52e-01 100.0% 47.7%
3270387 5070.1.1.1 alpha arrays › 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › UCR_14kD 0.60 44.0 4.03e-01 100.0% 58.1%
4028563 131.2.1.0 alpha complex topology › PDEase-like › Poly A polymerase C-terminal region-like › Poly A polymerase C-terminal region-like 0.55 47.0 3.17e-01 100.0% 49.8%
2321841 1016.1.1.1 alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Pan3_PK 0.54 46.0 3.85e-01 100.0% 65.5%
3606213 109.4.1.21 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ENTH 0.54 41.0 3.35e-01 97.4% 41.9%
4949960 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 34.0 3.15e-01 81.8% 49.0%
4026266 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.52 39.0 2.79e-01 88.3% 24.2%
4268279 3227.1.1.1 alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC 0.52 35.0 2.30e-01 83.1% 13.1%
4995739 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.51 43.0 3.45e-01 96.1% 97.0%