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IMGVR_UViG_3300025327_000197-3300025327-Ga0209751_100028105

Arc-Vir

IMGVR_UViG_3300025327_000197-3300025327-Ga0209751_100028105

Quality

90.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 45-224
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03167.26 best UDG 45.4 1.30e-11 81.7% 81.4%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ui0A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.91 80.0 7.83e-01 100.0% 84.4%
6ajpA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.86 80.0 7.54e-01 98.9% 83.5%
2d3yA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.79 75.0 6.92e-01 100.0% 81.3%
1mugA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.78 68.0 7.16e-01 100.0% 99.4%
1wywA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.75 69.0 6.48e-01 100.0% 81.0%
3ujpA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.67 42.0 5.13e-01 87.8% 97.4%
3s7zA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.66 44.0 5.15e-01 88.3% 96.0%
5w56B02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.65 41.0 4.76e-01 88.3% 88.3%
8a57D01 3.40.50.11060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › GTPase HflX, N-terminal domain 0.65 38.0 4.79e-01 82.8% 100.0%
3hh8A02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.64 43.0 4.95e-01 94.4% 92.4%
2hqbA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 41.0 4.73e-01 87.2% 87.8%
4ry8A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 42.0 4.64e-01 88.3% 81.8%
3pdiA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.63 44.0 4.69e-01 86.1% 81.8%
2dgdA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 33.0 4.41e-01 70.6% 100.0%
3g13B00 3.40.50.1390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Resolvase, N-terminal catalytic domain 0.61 38.0 4.30e-01 82.2% 80.4%
4ldaB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 39.0 4.59e-01 87.8% 91.3%
4lflA00 3.40.1400.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribose 5-phosphate Isomerase B; Chain: A, › Sugar-phosphate isomerase, RpiB/LacA/LacB 0.61 42.0 4.61e-01 86.7% 88.0%
6fxsA00 3.40.1400.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribose 5-phosphate Isomerase B; Chain: A, › Sugar-phosphate isomerase, RpiB/LacA/LacB 0.60 43.0 4.63e-01 87.2% 87.9%
3gbvA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 40.0 4.35e-01 82.8% 81.2%
2xdqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.59 41.0 4.66e-01 95.6% 94.9%
1jx6A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 41.0 4.18e-01 87.8% 72.0%
4bg8A01 3.30.420.430 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.58 38.0 4.38e-01 86.1% 91.5%
4hh3C02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.58 41.0 4.74e-01 96.7% 99.2%
1ptmA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.58 48.0 3.93e-01 88.3% 98.8%
4gw3A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 47.0 4.04e-01 87.2% 99.3%
3m9wA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 39.0 4.14e-01 79.4% 77.2%
2i71A01 3.40.50.10640 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SSO1389-like 0.57 46.0 4.31e-01 85.0% 81.6%
4j5rA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.57 39.0 4.41e-01 80.0% 90.1%
1qv9A01 3.40.50.10830 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) 0.57 42.0 4.56e-01 87.2% 90.3%
3tb6B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 40.0 4.34e-01 87.2% 88.4%
4uhwA09 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.56 23.0 3.06e-01 86.7% 66.7%
1t3tA04 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.56 46.0 3.79e-01 87.2% 80.5%
2h8gA00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.55 46.0 4.13e-01 87.2% 95.5%
7c2xA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 44.0 3.83e-01 86.7% 96.7%
1a9yA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 4.20e-01 87.2% 95.3%
4axvA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 49.0 4.43e-01 99.4% 88.8%
5f5nA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 44.0 3.73e-01 87.8% 68.2%
3lxuX01 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.53 48.0 3.91e-01 98.3% 76.0%
1gteA03 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 44.0 4.29e-01 87.8% 86.2%
4mcjG00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 42.0 4.46e-01 95.0% 97.4%
2jjmA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.52 43.0 4.40e-01 87.8% 98.3%
3aw9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 43.0 4.24e-01 87.8% 94.3%
5nckA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 31.0 3.91e-01 70.6% 100.0%
1fs0G01 3.40.1380.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit 0.52 33.0 3.84e-01 82.8% 88.5%
3e48A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 4.27e-01 86.7% 89.1%
4umlA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.52 39.0 3.81e-01 78.3% 72.6%
2p11A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.52 40.0 4.36e-01 88.3% 99.3%
5j60A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 44.0 4.30e-01 90.6% 93.9%
3ihlB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 42.0 3.90e-01 87.8% 99.1%
3g5cA01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.51 42.0 4.03e-01 87.2% 93.7%
2wjwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 40.0 4.19e-01 85.6% 89.0%
1yp1A00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.51 42.0 4.08e-01 87.2% 95.5%
1ekjA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.51 43.0 4.14e-01 91.1% 89.0%
3eafA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 42.0 4.03e-01 87.8% 77.3%
3lkbA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 42.0 3.95e-01 87.8% 74.4%
3sggA02 3.20.20.490 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › GxGYxYP glycoside hydrolase, C-terminal domain 0.50 42.0 3.82e-01 92.2% 96.9%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4962559 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.93 80.0 7.99e-01 100.0% 86.5%
5021506 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.92 75.0 7.47e-01 98.9% 81.6%
3386994 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.91 74.0 7.57e-01 98.3% 85.7%
4352085 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.90 81.0 7.74e-01 100.0% 82.5%
4937539 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.90 76.0 7.53e-01 99.4% 83.8%
4990486 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.90 80.0 7.81e-01 100.0% 86.3%
4943408 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.89 79.0 7.56e-01 100.0% 81.5%
4968429 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.89 79.0 7.72e-01 100.0% 85.8%
4318718 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.89 74.0 7.53e-01 98.3% 88.0%
3839117 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.87 71.0 7.11e-01 100.0% 83.9%
3057088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 80.0 7.42e-01 98.9% 80.0%
4995737 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 80.0 7.74e-01 100.0% 89.7%
3965875 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 68.0 7.23e-01 100.0% 93.8%
3590878 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.83 80.0 7.50e-01 100.0% 89.5%
4964719 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.82 74.0 7.10e-01 100.0% 84.0%
4965816 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.82 75.0 7.11e-01 95.0% 100.0%
3960892 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.81 66.0 6.50e-01 93.3% 80.0%
4964088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.78 71.0 6.95e-01 100.0% 89.5%
2070922 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.78 69.0 5.92e-01 100.0% 61.8%
4999526 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.76 65.0 6.39e-01 97.8% 84.2%
3739448 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.76 70.0 6.83e-01 100.0% 89.7%
5066830 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.74 66.0 6.52e-01 100.0% 88.9%
5032364 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.72 67.0 6.49e-01 98.9% 100.0%
4956359 7566.1.1.2 a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N 0.64 40.0 4.02e-01 86.1% 59.5%
4057613 7566.1.1.1 a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N,GTP-bdg_M 0.64 39.0 3.89e-01 83.9% 56.3%
4952034 7565.1.1.1 a/b three-layered sandwiches › Resolvase-like › Resolvase-like › Resolvase-like › Resolvase 0.64 39.0 4.38e-01 86.7% 77.9%
4040940 2007.1.2.5 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp 0.63 45.0 4.38e-01 87.8% 65.5%
3229926 7590.1.1.2 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.63 46.0 4.73e-01 87.2% 80.0%
2049835 2007.1.14.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Oxidored_nitro 0.60 43.0 4.59e-01 96.7% 84.3%
3423082 7566.1.1.1 a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N,GTP-bdg_M 0.60 38.0 3.75e-01 84.4% 56.5%
3840840 7566.1.1.1 a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N,GTP-bdg_M 0.60 39.0 3.67e-01 83.3% 52.7%
3332111 7590.1.1.2 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.59 43.0 4.21e-01 86.1% 68.0%
5016073 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.58 49.0 4.80e-01 87.8% 100.0%
4164599 2007.1.2.5 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp 0.58 49.0 3.92e-01 87.8% 79.1%
3171720 2006.1.1.28 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › APP1_cat 0.57 48.0 4.43e-01 87.8% 100.0%
5024115 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.57 40.0 4.11e-01 92.8% 74.7%
4627252 7589.1.1.2 a/b three-layered sandwiches › YgbK-like › YgbK-like › YgbK-like › NBD_C 0.56 47.0 4.84e-01 87.2% 98.2%
4937008 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.56 47.0 4.52e-01 87.2% 95.6%
4949615 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.56 44.0 4.63e-01 82.8% 100.0%
5061175 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 45.0 4.58e-01 83.3% 97.1%
5015776 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 45.0 4.44e-01 87.2% 99.0%
None 0.55 45.0 4.44e-01 87.2% 98.5%
5064933 2004.1.1.141 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CTP_synth_N 0.55 45.0 4.33e-01 87.8% 97.6%
3603676 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 45.0 4.36e-01 87.8% 98.0%
144300 7529.1.1.1 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Macro 0.55 38.0 4.15e-01 71.7% 84.1%
5038195 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.54 44.0 4.51e-01 83.9% 98.3%
4999389 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.54 45.0 4.43e-01 87.2% 94.8%
3964279 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.54 43.0 4.61e-01 83.3% 99.4%
2841469 7512.1.1.22 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › A-2_8-polyST 0.54 45.0 4.35e-01 86.1% 97.0%
3961470 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.54 50.0 4.59e-01 100.0% 88.5%
3968586 2007.5.1.23 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › SGNH 0.54 50.0 4.31e-01 100.0% 91.3%
452389 2003.1.1.67 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.54 44.0 3.80e-01 87.2% 68.0%
3704350 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.53 40.0 4.42e-01 88.9% 100.0%
4524961 2007.1.3.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › UPF0004 0.53 37.0 4.00e-01 95.6% 84.7%
3243089 2007.5.1.23 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › SGNH 0.53 47.0 4.08e-01 96.1% 88.9%
4305337 7512.1.1.117 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28, Glyco_tran_28_C 0.53 44.0 3.44e-01 87.8% 99.5%
4934190 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.53 46.0 4.32e-01 92.2% 82.3%
4944234 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 42.0 4.34e-01 83.3% 96.0%
3061339 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.52 43.0 3.33e-01 87.8% 75.8%
4286843 7512.1.1.10 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 0.52 43.0 4.12e-01 86.7% 100.0%
4178958 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.52 40.0 3.66e-01 78.9% 68.7%
5002363 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.52 48.0 4.29e-01 100.0% 83.2%
3997856 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 43.0 3.10e-01 87.8% 41.6%
3270723 2011.2.1.1 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PNP_UDP_1 0.52 47.0 4.26e-01 100.0% 97.2%
4332786 7512.1.1.10 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 0.51 43.0 4.33e-01 87.8% 98.9%
5035356 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.51 40.0 3.91e-01 81.7% 97.0%
4987831 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.51 41.0 4.05e-01 83.9% 99.5%
3989136 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.51 39.0 3.62e-01 78.3% 84.5%
4980524 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.51 40.0 4.06e-01 81.7% 96.6%
4851730 2498.1.1.4 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin 0.50 41.0 3.92e-01 87.2% 91.5%
4994638 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.50 45.0 4.01e-01 97.8% 86.9%
3604894 2004.1.1.141 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CTP_synth_N 0.50 42.0 3.53e-01 90.6% 89.2%
3889598 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.50 40.0 3.34e-01 85.0% 69.4%
D2 high residues 238-465
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01612.27 best DNA_pol_A_exo1 72.0 7.80e-20 87.7% 94.8%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.92 83.0 8.59e-01 99.1% 97.7%
6vddD01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.90 70.0 7.85e-01 100.0% 99.5%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.88 72.0 7.83e-01 100.0% 98.5%
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.88 75.0 7.28e-01 99.6% 80.2%
1bdp001 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.87 70.0 7.59e-01 99.1% 97.4%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.86 71.0 6.70e-01 100.0% 72.9%
1qssA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.86 57.0 6.91e-01 99.1% 98.7%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.85 71.0 6.59e-01 100.0% 70.0%
3cymA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 70.0 7.32e-01 100.0% 94.2%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 80.0 7.69e-01 100.0% 98.8%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 62.0 6.90e-01 88.6% 94.1%
7pbkA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 74.0 7.53e-01 100.0% 96.8%
7jw6A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 68.0 7.00e-01 95.2% 94.9%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 59.0 6.31e-01 87.3% 90.5%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 66.0 6.92e-01 94.3% 98.1%
1s5jA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 55.0 5.94e-01 76.8% 100.0%
4fzxC00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 51.0 6.01e-01 86.0% 100.0%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.71 67.0 6.43e-01 97.4% 99.2%
1x9mA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 62.0 6.23e-01 91.2% 99.6%
1uocB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 64.0 6.19e-01 96.9% 93.3%
7t2sA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 51.0 5.85e-01 82.0% 100.0%
2qxfA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.68 53.0 5.83e-01 80.7% 100.0%
1y97A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 54.0 5.78e-01 89.9% 99.5%
2f96A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 51.0 5.49e-01 82.5% 94.5%
1j9aA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.63 50.0 5.48e-01 85.1% 100.0%
4ddnA00 2.100.10.30 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Jacalin-like lectin domain 0.53 25.0 3.02e-01 98.2% 64.3%
3mfnB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 29.0 3.82e-01 78.1% 95.2%
1tqyB02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.51 27.0 3.30e-01 98.2% 77.0%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 23.0 2.96e-01 82.0% 70.7%
ECOD (89)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.93 85.0 6.31e-01 100.0% 43.5%
4037090 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.92 83.0 8.48e-01 100.0% 95.0%
3980678 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.92 79.0 6.72e-01 93.9% 59.7%
4233346 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.92 81.0 6.94e-01 98.2% 62.4%
4975018 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 76.0 8.27e-01 99.6% 99.5%
3388110 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.91 79.0 6.80e-01 98.7% 61.5%
3965745 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.90 81.0 7.55e-01 100.0% 76.7%
4677993 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.90 82.0 8.36e-01 99.1% 96.8%
4995738 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 81.0 8.27e-01 100.0% 96.4%
4333172 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 73.0 7.81e-01 99.6% 96.0%
2469642 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 74.0 7.76e-01 100.0% 93.7%
3165932 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 73.0 7.58e-01 100.0% 89.8%
4165451 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 81.0 7.93e-01 100.0% 87.8%
4031810 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.88 71.0 7.70e-01 98.7% 97.4%
4882444 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 73.0 7.71e-01 100.0% 95.1%
4188496 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 70.0 7.69e-01 98.2% 98.9%
4367091 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 70.0 6.26e-01 99.1% 62.0%
1187764 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 71.0 6.70e-01 100.0% 72.5%
4882445 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 72.0 7.65e-01 100.0% 95.1%
3993770 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 72.0 6.65e-01 100.0% 69.6%
4029824 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.86 75.0 6.90e-01 100.0% 72.5%
3185973 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.85 72.0 6.62e-01 100.0% 70.1%
3600259 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 71.0 5.55e-01 100.0% 44.8%
3434621 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 72.0 6.59e-01 100.0% 71.4%
1756776 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 72.0 6.49e-01 100.0% 69.2%
2579558 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.83 68.0 7.21e-01 95.6% 94.6%
3283743 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.82 71.0 6.09e-01 100.0% 60.3%
3956762 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 70.0 7.29e-01 100.0% 95.2%
160349 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 63.0 6.81e-01 88.6% 91.8%
3908305 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 64.0 6.79e-01 89.9% 89.3%
4291004 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.82 65.0 5.77e-01 99.6% 60.7%
3705325 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 75.0 6.96e-01 100.0% 78.9%
3817603 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 78.0 6.00e-01 100.0% 88.2%
3261268 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.81 78.0 6.35e-01 100.0% 67.0%
5038805 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.80 58.0 6.20e-01 83.3% 82.0%
3359530 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 77.0 6.89e-01 100.0% 86.9%
3407164 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 73.0 7.48e-01 98.7% 98.2%
3661219 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 64.0 6.53e-01 93.4% 84.4%
4028087 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 71.0 7.34e-01 100.0% 98.6%
2810987 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 64.0 6.85e-01 88.6% 94.5%
5066483 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.79 58.0 6.70e-01 82.5% 100.0%
4933243 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.79 59.0 6.75e-01 85.1% 100.0%
4028967 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 70.0 5.86e-01 99.6% 58.6%
3608338 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.78 64.0 4.73e-01 91.7% 36.7%
2704792 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 70.0 7.07e-01 99.1% 93.8%
5056095 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.77 58.0 6.23e-01 83.3% 87.4%
3892440 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 74.0 7.20e-01 100.0% 96.7%
3397064 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 66.0 6.41e-01 96.9% 81.2%
3591717 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 61.0 6.55e-01 90.8% 93.5%
4025342 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 72.0 7.13e-01 99.1% 97.9%
5080048 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.76 57.0 6.51e-01 80.3% 100.0%
2725515 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 67.0 6.84e-01 95.2% 95.0%
5055213 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.74 59.0 6.47e-01 85.1% 97.9%
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.74 71.0 5.47e-01 100.0% 64.9%
3604297 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.74 56.0 6.35e-01 83.8% 100.0%
3953516 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.74 57.0 6.12e-01 88.6% 91.3%
4037317 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.74 57.0 6.06e-01 86.0% 88.8%
3537255 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.74 67.0 6.44e-01 96.9% 85.6%
3088601 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.73 53.0 6.11e-01 82.9% 97.7%
3265862 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 65.0 5.93e-01 97.4% 73.3%
4432985 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.73 57.0 6.14e-01 86.4% 92.5%
4018545 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 69.0 6.33e-01 98.7% 80.4%
4298195 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.72 57.0 6.09e-01 87.3% 92.0%
3685910 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 60.0 6.24e-01 87.3% 91.2%
5045899 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.71 55.0 6.14e-01 83.8% 99.4%
5081840 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.71 57.0 6.02e-01 89.9% 90.4%
5081301 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.71 56.0 4.61e-01 86.4% 47.4%
3733641 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 54.0 6.01e-01 81.1% 97.8%
5052601 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.70 56.0 6.16e-01 85.5% 98.4%
3957139 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 57.0 6.13e-01 90.8% 96.0%
3275838 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 65.0 6.35e-01 96.9% 91.0%
3715980 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 65.0 6.21e-01 96.9% 96.9%
4024811 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.70 59.0 5.45e-01 87.7% 92.5%
3600160 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 65.0 6.19e-01 98.2% 100.0%
4029137 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.67 54.0 5.45e-01 90.4% 81.7%
3927943 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 62.0 6.03e-01 100.0% 89.2%
3259996 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 62.0 6.06e-01 98.7% 89.9%
4044377 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.67 59.0 4.56e-01 92.5% 76.0%
3781214 2484.1.1.90 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDDh_C 0.66 51.0 5.09e-01 83.3% 75.6%
1501363 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.66 58.0 4.52e-01 92.5% 75.8%
3941572 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.65 58.0 5.03e-01 93.0% 67.8%
3706908 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.65 55.0 5.16e-01 89.5% 80.0%
4299237 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.65 52.0 5.40e-01 82.5% 91.9%
4044396 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.64 51.0 5.44e-01 82.5% 93.7%
3682884 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.64 59.0 5.94e-01 100.0% 96.9%
2499661 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.64 50.0 5.53e-01 83.3% 100.0%
4381276 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.64 51.0 5.22e-01 82.9% 86.6%
3778404 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.63 49.0 5.10e-01 82.5% 85.7%
4959100 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 51.0 4.74e-01 87.7% 82.1%
D3 medium residues 466-569
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 41.6 1.10e-10 95.2% 23.9%
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.92 50.0 6.08e-01 100.0% 80.3%
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.89 83.0 8.03e-01 100.0% 88.7%
1t7pA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.89 84.0 7.12e-01 99.0% 96.2%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.84 47.0 4.37e-01 99.0% 46.5%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 46.0 5.27e-01 95.2% 72.5%
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 47.0 4.28e-01 100.0% 48.1%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.78 46.0 4.19e-01 98.1% 46.9%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.77 45.0 5.61e-01 99.0% 96.8%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.75 41.0 3.74e-01 99.0% 40.4%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.74 42.0 3.62e-01 98.1% 37.0%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.73 38.0 4.18e-01 99.0% 59.8%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.72 45.0 4.34e-01 98.1% 55.1%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.72 38.0 4.23e-01 100.0% 63.9%
5zbqA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.72 44.0 3.14e-01 99.0% 21.8%
7sf7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.71 41.0 3.03e-01 96.2% 22.1%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 44.0 4.45e-01 98.1% 63.7%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.69 46.0 5.21e-01 97.1% 88.7%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.68 41.0 3.80e-01 96.2% 48.1%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 45.0 4.03e-01 100.0% 51.1%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.67 35.0 3.91e-01 97.1% 64.6%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.66 48.0 4.08e-01 100.0% 47.9%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 43.0 4.35e-01 97.1% 65.4%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 44.0 5.31e-01 94.2% 100.0%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.66 41.0 4.29e-01 99.0% 68.4%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.65 40.0 4.21e-01 95.2% 68.5%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 37.0 4.00e-01 97.1% 67.1%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.64 49.0 5.11e-01 99.0% 86.5%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 42.0 4.27e-01 99.0% 68.6%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 49.0 5.08e-01 98.1% 87.0%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 38.0 4.11e-01 98.1% 75.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 43.0 4.84e-01 99.0% 96.2%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 41.0 4.06e-01 100.0% 66.4%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 44.0 4.01e-01 100.0% 57.7%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 43.0 4.32e-01 98.1% 72.2%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.60 43.0 4.66e-01 99.0% 88.5%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 43.0 3.94e-01 100.0% 57.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 39.0 4.45e-01 99.0% 91.0%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 40.0 4.46e-01 99.0% 91.5%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.57 50.0 3.84e-01 100.0% 44.4%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 35.0 3.60e-01 99.0% 62.1%
6yttA01 1.10.8.190 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Carbon monoxide dehydrogenase alpha subunit. Chain M, domain 1 0.56 35.0 3.65e-01 90.4% 66.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 41.0 4.18e-01 99.0% 78.8%
1nu7D01 1.20.120.750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 0.56 35.0 3.26e-01 98.1% 47.4%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 50.0 4.40e-01 98.1% 98.7%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.55 51.0 4.92e-01 100.0% 100.0%
2v6eA01 1.10.287.3180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 32.0 3.76e-01 99.0% 82.7%
2xgjA04 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.54 50.0 4.60e-01 100.0% 98.5%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 36.0 3.31e-01 98.1% 53.0%
3h1nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 38.0 3.67e-01 97.1% 64.2%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.53 38.0 3.88e-01 75.0% 95.1%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 48.0 4.11e-01 100.0% 66.5%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.52 31.0 3.13e-01 89.4% 57.1%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.51 48.0 4.21e-01 98.1% 85.6%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 48.0 3.69e-01 99.0% 67.9%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.50 44.0 3.02e-01 99.0% 49.4%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 46.0 3.86e-01 100.0% 63.0%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.50 47.0 3.67e-01 99.0% 51.0%
5tcsA01 1.10.418.30 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Ncd80 complex, Ncd80 subunit 0.50 36.0 3.63e-01 76.9% 87.2%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 85.0 5.30e-01 100.0% 21.7%
2970331 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.91 83.0 6.70e-01 100.0% 55.7%
1391185 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 84.0 6.69e-01 100.0% 54.6%
3676005 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 86.0 5.54e-01 100.0% 26.0%
3964115 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.89 85.0 7.79e-01 100.0% 80.0%
3616267 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.89 83.0 6.85e-01 100.0% 60.0%
3333792 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.89 84.0 6.89e-01 100.0% 59.4%
3580212 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.88 77.0 8.05e-01 94.2% 100.0%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.87 83.0 5.31e-01 100.0% 26.3%
3483300 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.84 79.0 6.03e-01 100.0% 55.9%
3626481 603.1.1.105 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 0.79 49.0 4.79e-01 98.1% 59.1%
4929286 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.79 38.0 4.72e-01 97.1% 73.8%
3918080 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 41.0 4.20e-01 99.0% 58.0%
3228159 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 45.0 3.95e-01 98.1% 44.0%
3295653 4268.2.1.0 alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA 0.71 46.0 4.36e-01 99.0% 55.8%
3497641 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.70 41.0 4.25e-01 99.0% 61.0%
3543620 604.1.1.95 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KIAA1755_C 0.68 43.0 4.49e-01 100.0% 69.5%
3489764 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.68 42.0 4.26e-01 97.1% 61.9%
3801688 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 43.0 4.34e-01 98.1% 63.8%
3776117 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 44.0 4.10e-01 98.1% 53.8%
3218730 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 37.0 4.22e-01 94.2% 74.7%
3424514 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.66 54.0 5.12e-01 99.0% 75.0%
3505438 604.1.1.67 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.66 45.0 4.63e-01 100.0% 73.0%
3858356 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.65 50.0 4.42e-01 100.0% 57.2%
3770420 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 43.0 4.02e-01 99.0% 55.2%
3579522 604.1.1.98 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 0.65 45.0 4.54e-01 99.0% 70.5%
3569017 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.64 40.0 3.46e-01 99.0% 40.6%
3387232 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.62 44.0 4.55e-01 100.0% 76.0%
3419202 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.62 41.0 3.78e-01 97.1% 53.1%
5043886 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.62 50.0 4.19e-01 99.0% 52.4%
4036645 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.62 42.0 3.44e-01 99.0% 37.4%
4360632 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.61 49.0 4.22e-01 100.0% 57.3%
3938350 604.1.1.67 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.60 41.0 4.11e-01 100.0% 68.6%
3678972 604.6.1.38 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › CASP_dom 0.59 42.0 4.17e-01 100.0% 69.7%
1268315 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.59 45.0 4.23e-01 99.0% 67.5%
5019699 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 52.0 4.24e-01 99.0% 54.4%
3579767 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.58 41.0 4.07e-01 100.0% 70.0%
3935032 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.58 40.0 4.04e-01 98.1% 71.4%
5031623 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.57 40.0 3.67e-01 96.2% 54.7%
3939162 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 38.0 3.68e-01 94.2% 60.8%
3616476 4177.1.1.6 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.55 37.0 2.97e-01 99.0% 34.0%
3678718 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.54 37.0 3.79e-01 98.1% 69.5%
1685105 160.1.1.4 alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_VA_C 0.54 35.0 3.84e-01 99.0% 81.9%
3606235 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.53 50.0 4.16e-01 100.0% 70.0%
3630462 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 50.0 4.42e-01 100.0% 85.7%
4972577 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.52 50.0 3.57e-01 100.0% 97.4%
4571188 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 50.0 4.57e-01 100.0% 80.0%
4167563 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 47.0 4.38e-01 100.0% 79.2%
D4 medium residues 570-635_785-875
PDB
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.89 68.0 7.70e-01 91.7% 100.0%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.86 78.0 7.41e-01 93.6% 100.0%
4x0qA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.85 73.0 7.69e-01 94.3% 97.9%
1sc6A03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 39.0 5.24e-01 75.8% 100.0%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 43.0 5.40e-01 96.2% 100.0%
5llwA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 54.0 5.75e-01 96.2% 92.0%
2qyxB01 3.30.70.1360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › mj0159-like 0.69 35.0 4.15e-01 93.0% 69.7%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.68 57.0 5.71e-01 94.9% 85.3%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.68 56.0 5.81e-01 99.4% 91.3%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.67 53.0 5.02e-01 82.8% 73.8%
6pwjA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.67 55.0 5.47e-01 94.3% 82.4%
1q2lA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.67 48.0 4.24e-01 74.5% 91.7%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 49.0 4.72e-01 96.8% 69.2%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 56.0 5.83e-01 95.5% 96.5%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 49.0 5.42e-01 91.7% 99.2%
3tvkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 58.0 5.61e-01 94.9% 85.5%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.65 47.0 4.15e-01 74.5% 88.5%
3hvwA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 54.0 5.47e-01 94.9% 86.8%
1y10B02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.65 52.0 4.96e-01 84.1% 73.2%
4iobA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 56.0 5.62e-01 91.7% 90.1%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.64 48.0 5.15e-01 82.2% 90.3%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.64 44.0 4.87e-01 91.7% 86.2%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.63 54.0 5.03e-01 100.0% 73.7%
3mr7A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.63 48.0 4.69e-01 98.1% 72.3%
4zmuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 54.0 5.46e-01 93.0% 91.6%
3ezuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 52.0 5.35e-01 94.3% 91.2%
2hfsA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.61 38.0 3.92e-01 94.9% 65.1%
1yk9A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.61 50.0 4.78e-01 97.5% 73.9%
6yiiA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.59 54.0 4.81e-01 96.8% 71.3%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.59 42.0 4.10e-01 72.6% 91.6%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.51 39.0 3.93e-01 80.3% 86.8%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3486431 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.85 59.0 4.51e-01 70.1% 96.2%
3601834 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.84 58.0 6.91e-01 70.1% 99.1%
3613455 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 66.0 7.06e-01 80.9% 100.0%
4994641 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.72 44.0 5.45e-01 96.2% 100.0%
None 0.69 61.0 4.26e-01 94.3% 83.5%
None 0.68 61.0 4.21e-01 94.3% 84.1%
None 0.68 61.0 4.14e-01 94.9% 85.3%
139439 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.68 57.0 5.71e-01 94.9% 85.3%
4934750 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.68 46.0 5.42e-01 98.7% 99.1%
3945961 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.68 59.0 5.84e-01 94.9% 87.3%
3942347 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.68 55.0 5.47e-01 93.6% 83.1%
3973496 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.67 61.0 5.97e-01 100.0% 90.3%
3286133 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.67 58.0 5.82e-01 94.9% 90.0%
3967247 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.67 60.0 5.73e-01 94.9% 91.7%
3280378 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 54.0 5.35e-01 86.0% 86.1%
4586449 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.66 52.0 4.79e-01 81.5% 74.4%
4285081 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.65 57.0 5.39e-01 94.9% 79.4%
5055913 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 39.0 4.59e-01 91.7% 84.5%
5029961 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.65 46.0 5.12e-01 98.7% 91.2%
4193555 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.65 46.0 5.16e-01 98.7% 94.2%
4373656 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.64 44.0 5.01e-01 98.1% 93.9%
3957787 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.64 54.0 4.88e-01 100.0% 66.7%
4007900 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.64 55.0 4.89e-01 94.9% 66.5%
4065577 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.63 54.0 4.70e-01 100.0% 61.3%
5031880 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.63 42.0 4.90e-01 97.5% 98.1%
4000490 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.62 53.0 4.43e-01 100.0% 54.2%
5028094 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 49.0 4.65e-01 82.8% 91.9%
4947537 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 55.0 4.84e-01 97.5% 66.8%
4930192 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 48.0 4.67e-01 81.5% 94.9%
5057809 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 48.0 4.53e-01 82.2% 92.1%
5032300 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.61 49.0 4.58e-01 84.7% 90.8%
3955909 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 51.0 4.22e-01 98.7% 52.3%
5024461 304.28.1.38 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › CAA_C 0.61 47.0 4.63e-01 79.6% 95.8%
4929747 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.61 53.0 4.71e-01 100.0% 66.5%
5071942 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.61 48.0 4.40e-01 82.2% 88.0%
4941715 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.60 46.0 5.10e-01 99.4% 100.0%
4942908 304.1.1.3 a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › MDD_C 0.60 41.0 4.12e-01 96.2% 67.5%
3603366 304.48.1.31 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.58 53.0 5.00e-01 97.5% 81.6%
4856819 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.58 52.0 4.67e-01 98.7% 70.9%
3594228 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.57 53.0 4.64e-01 98.7% 70.5%
3953369 304.4.1.2 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.56 35.0 4.12e-01 89.2% 89.9%
5036793 304.48.1.31 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.56 50.0 4.79e-01 97.5% 82.2%
None 0.56 52.0 4.44e-01 99.4% 65.7%
3883719 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.56 52.0 3.52e-01 99.4% 30.1%
4174585 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.56 42.0 4.25e-01 77.7% 93.5%
3712831 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 42.0 3.49e-01 93.6% 46.4%
D5 medium residues 636-647_733-784
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.94 89.0 6.57e-01 100.0% 94.4%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.93 87.0 6.47e-01 100.0% 94.4%
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.92 86.0 6.42e-01 100.0% 93.8%
4dsfA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.92 86.0 7.02e-01 100.0% 92.7%
7pbkB02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.72 65.0 5.04e-01 100.0% 97.8%
4gcvC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 37.0 2.90e-01 93.8% 27.0%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 48.0 3.14e-01 100.0% 21.1%
1llaA03 1.10.1280.10 Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase 0.56 42.0 2.86e-01 82.8% 21.3%
3wkyA02 1.10.1280.10 Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase 0.54 42.0 2.79e-01 85.9% 21.4%
2zj2A03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 36.0 3.31e-01 95.3% 51.2%
1bccH00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.54 31.0 3.11e-01 78.1% 53.0%
1s9qA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 41.0 3.03e-01 98.4% 75.9%
1a52A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 41.0 2.93e-01 96.9% 73.2%
2pw4A00 1.10.3300.10 Mainly Alpha › Orthogonal Bundle › Jann2411-like fold › Jann2411-like domain 0.51 42.0 3.13e-01 95.3% 62.3%
2r40D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 43.0 2.97e-01 96.9% 70.8%
1yowA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 41.0 2.94e-01 96.9% 73.0%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3711347 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.94 89.0 6.63e-01 100.0% 95.7%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.94 86.0 6.38e-01 96.9% 93.7%
3595356 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.92 75.0 5.85e-01 85.9% 100.0%
3581048 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.92 86.0 6.28e-01 100.0% 87.7%
3562851 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.92 85.0 6.30e-01 98.4% 94.5%
4848450 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.91 78.0 5.84e-01 90.6% 93.5%
4456463 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 76.0 5.86e-01 90.6% 99.2%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 80.0 6.06e-01 96.9% 96.4%
4169333 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 73.0 5.65e-01 85.9% 100.0%
4876668 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.89 72.0 5.65e-01 85.9% 100.0%
3969341 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.89 71.0 5.53e-01 84.4% 100.0%
3654151 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 77.0 5.57e-01 95.3% 96.4%
3386797 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 80.0 5.30e-01 100.0% 58.5%
2579554 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.84 73.0 5.50e-01 95.3% 89.9%
4217329 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 60.0 4.86e-01 81.2% 100.0%
3277186 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.76 57.0 4.53e-01 79.7% 100.0%
3423772 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.68 59.0 4.78e-01 93.8% 71.3%
4454880 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.60 41.0 3.90e-01 70.3% 88.0%
3795394 188.1.1.0 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain 0.55 43.0 3.26e-01 90.6% 46.3%
4972215 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 39.0 2.79e-01 79.7% 23.8%
965446 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.54 44.0 3.13e-01 98.4% 64.4%
4555698 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.53 41.0 2.90e-01 95.3% 67.5%
4115648 3671.1.1.1 alpha duplicates or obligate multimers › Translocated intimin receptor Tir extracellular domain › Translocated intimin receptor Tir extracellular domain › Translocated intimin receptor Tir extracellular domain › Tir_receptor_M 0.52 36.0 3.35e-01 87.5% 55.3%
4338423 152.1.2.1 alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 0.52 41.0 3.68e-01 100.0% 61.1%
3972346 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 42.0 2.40e-01 93.8% 65.0%
3276029 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 37.0 2.16e-01 79.7% 14.5%
D6 medium residues 648-732
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.64 49.0 4.09e-01 100.0% 47.9%
1zarA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 38.0 3.74e-01 97.6% 64.0%
6qm7A00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.55 41.0 3.02e-01 96.5% 27.9%
1z6tA03 1.10.8.430 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Helical domain of apoptotic protease-activating factors 0.52 35.0 3.56e-01 76.5% 69.1%
7o06C01 3.30.1470.10 Alpha Beta › 2-Layer Sandwich › Photosystem 1 Reaction Centre Subunit Ii; Chain: D; › Photosystem I PsaD, reaction center subunit II 0.50 35.0 3.51e-01 74.1% 86.8%
1j1vA00 1.10.1750.10 Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain 0.50 37.0 3.67e-01 88.2% 72.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3969341 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.81 65.0 5.68e-01 100.0% 58.4%
4169333 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 64.0 5.59e-01 100.0% 58.4%
4456463 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.79 63.0 5.45e-01 100.0% 56.2%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.78 64.0 5.35e-01 100.0% 52.9%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.78 68.0 5.97e-01 100.0% 65.8%
4876668 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.78 62.0 5.49e-01 100.0% 58.9%
4975020 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.78 67.0 5.71e-01 100.0% 58.5%
3277186 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.77 63.0 5.48e-01 100.0% 60.0%
4027630 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.76 65.0 5.77e-01 100.0% 65.8%
3001792 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.75 65.0 5.77e-01 100.0% 66.9%
3562851 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.75 61.0 5.11e-01 100.0% 51.7%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.66 52.0 4.40e-01 100.0% 51.0%
4995740 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.61 54.0 4.81e-01 100.0% 70.4%
4076819 102.1.1.79 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD+HHH_2+HHH_5 0.56 48.0 3.71e-01 95.3% 44.7%
5073703 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.56 32.0 3.84e-01 100.0% 94.0%
3269516 102.1.1.41 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › EME1-MUS81_C 0.54 43.0 4.16e-01 87.1% 98.9%
4021211 7579.1.1.34 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Tannase 0.53 40.0 2.47e-01 81.2% 35.6%
3194488 2.9.1.1 beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB 0.52 37.0 2.35e-01 74.1% 33.2%