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IMGVR_UViG_3300025333_000004-3300025333-Ga0208137_1003632
Arc-VirIMGVR_UViG_3300025333_000004-3300025333-Ga0208137_1003632
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 156-217
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3d5lA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.75 | 52.0 | 5.87e-01 | 75.8% | 100.0% |
| 3ilxA02 | 1.10.287.2170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 44.0 | 5.23e-01 | 74.2% | 86.4% |
| 2mx8A01 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.72 | 58.0 | 4.79e-01 | 88.7% | 56.6% |
| 3beyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.72 | 53.0 | 4.61e-01 | 83.9% | 52.1% |
| 2cwqA00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.72 | 54.0 | 4.31e-01 | 82.3% | 40.5% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.71 | 56.0 | 4.82e-01 | 88.7% | 60.4% |
| 3hjlA03 | 1.20.5.2020 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.70 | 45.0 | 5.01e-01 | 71.0% | 97.6% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.70 | 54.0 | 4.90e-01 | 83.9% | 63.9% |
| 1kf6C00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.69 | 51.0 | 4.01e-01 | 80.6% | 37.7% |
| 4a18Q01 | 1.10.10.1760 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L36 | 0.69 | 50.0 | 4.90e-01 | 79.0% | 72.5% |
| 3dfgA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.68 | 48.0 | 5.32e-01 | 77.4% | 97.9% |
| 2klqA00 | 1.20.58.870 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 53.0 | 4.45e-01 | 90.3% | 62.3% |
| 1konA01 | 1.10.10.200 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain | 0.66 | 50.0 | 4.88e-01 | 88.7% | 75.0% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.65 | 56.0 | 3.89e-01 | 98.4% | 86.4% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 44.0 | 4.35e-01 | 71.0% | 86.6% |
| 4a1nA02 | 6.10.250.1250 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 46.0 | 4.97e-01 | 95.2% | 98.0% |
| 3w6zA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.63 | 54.0 | 4.44e-01 | 98.4% | 96.7% |
| 1juqC00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 49.0 | 3.78e-01 | 87.1% | 38.3% |
| 4gtnA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.63 | 49.0 | 4.64e-01 | 85.5% | 71.6% |
| 6e6qA00 | 1.10.10.1100 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BFD-like [2Fe-2S]-binding domain | 0.62 | 45.0 | 4.73e-01 | 79.0% | 100.0% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 42.0 | 3.63e-01 | 72.6% | 43.6% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 45.0 | 4.32e-01 | 77.4% | 68.5% |
| 1su0B00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.62 | 49.0 | 4.00e-01 | 95.2% | 58.8% |
| 2gmyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.61 | 51.0 | 4.00e-01 | 96.8% | 74.5% |
| 3jcuZ00 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.61 | 42.0 | 4.30e-01 | 72.6% | 73.8% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 42.0 | 3.79e-01 | 72.6% | 58.6% |
| 2q14B01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.60 | 50.0 | 3.49e-01 | 98.4% | 30.5% |
| 4muoA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.60 | 48.0 | 4.56e-01 | 85.5% | 73.6% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.60 | 44.0 | 4.52e-01 | 79.0% | 93.0% |
| 2oxlA00 | 1.20.5.5260 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 46.0 | 4.66e-01 | 88.7% | 100.0% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.59 | 49.0 | 4.32e-01 | 93.5% | 89.2% |
| 1vquA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.59 | 46.0 | 4.54e-01 | 85.5% | 79.1% |
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 4.35e-01 | 80.6% | 81.4% |
| 2rn7A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 46.0 | 4.55e-01 | 96.8% | 86.4% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 42.0 | 3.49e-01 | 75.8% | 42.7% |
| 3wirA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.58 | 44.0 | 2.72e-01 | 82.3% | 89.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 49.0 | 4.22e-01 | 96.8% | 89.2% |
| 3h5qA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.58 | 44.0 | 4.27e-01 | 85.5% | 75.7% |
| 3ph0C00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 41.0 | 4.38e-01 | 82.3% | 88.7% |
| 1mijA00 | 1.10.10.500 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeo-prospero domain | 0.58 | 48.0 | 3.83e-01 | 98.4% | 61.2% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.57 | 47.0 | 4.35e-01 | 88.7% | 85.7% |
| 4ga4A01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.57 | 42.0 | 4.21e-01 | 85.5% | 79.1% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.56 | 40.0 | 3.68e-01 | 77.4% | 58.0% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 45.0 | 3.80e-01 | 96.8% | 76.3% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.55 | 45.0 | 3.87e-01 | 93.5% | 91.2% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 38.0 | 3.94e-01 | 77.4% | 81.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 40.0 | 3.79e-01 | 83.9% | 85.2% |
| 6z01B01 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.53 | 42.0 | 3.99e-01 | 93.5% | 83.3% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.52 | 44.0 | 3.29e-01 | 98.4% | 67.4% |
| 1cukA03 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.52 | 37.0 | 4.17e-01 | 85.5% | 97.9% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4945443 | 2004.5.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain | 0.82 | 72.0 | 5.03e-01 | 96.8% | 98.9% |
| 5074258 | 608.1.1.0 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like | 0.77 | 58.0 | 5.76e-01 | 82.3% | 76.9% |
| 3611539 | 4198.1.1.0 ↗ | alpha arrays › TerB-like › TerB-like › TerB-like | 0.75 | 61.0 | 4.37e-01 | 90.3% | 31.9% |
| 4951600 | 608.1.1.1 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD | 0.72 | 53.0 | 4.27e-01 | 82.3% | 40.0% |
| 5060063 | 4133.1.1.0 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like | 0.71 | 58.0 | 5.66e-01 | 91.9% | 85.7% |
| 3932372 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.71 | 46.0 | 3.54e-01 | 71.0% | 30.0% |
| 3362789 | 4133.1.1.2 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 | 0.71 | 57.0 | 4.97e-01 | 91.9% | 60.0% |
| 5016721 | 6132.1.1.14 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › PF29261 | 0.70 | 56.0 | 5.69e-01 | 87.1% | 100.0% |
| 4936723 | 608.1.1.1 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD | 0.69 | 48.0 | 4.64e-01 | 77.4% | 65.2% |
| 3834278 | 4133.1.1.1 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › ENT | 0.69 | 56.0 | 5.60e-01 | 91.9% | 87.7% |
| 4479187 | 101.35.1.5 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 | 0.69 | 58.0 | 5.72e-01 | 95.2% | 90.8% |
| 3327522 | 101.35.1.5 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 | 0.68 | 57.0 | 5.53e-01 | 96.8% | 82.9% |
| 3345966 | 4133.1.1.0 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like | 0.67 | 57.0 | 5.44e-01 | 98.4% | 85.3% |
| 4323683 | 101.35.1.5 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 | 0.67 | 57.0 | 4.77e-01 | 96.8% | 55.5% |
| 3814803 | 4133.1.1.1 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › ENT | 0.66 | 58.0 | 5.39e-01 | 100.0% | 81.2% |
| 3390114 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.66 | 52.0 | 3.38e-01 | 87.1% | 36.5% |
| 3934174 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.66 | 53.0 | 3.54e-01 | 91.9% | 75.2% |
| 3926730 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.65 | 53.0 | 4.57e-01 | 96.8% | 55.2% |
| 3906253 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.65 | 52.0 | 4.26e-01 | 93.5% | 46.7% |
| 5038858 | 184.1.1.1 ↗ | alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Glycos_trans_3N | 0.64 | 49.0 | 4.90e-01 | 82.3% | 80.0% |
| 3717244 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.64 | 51.0 | 4.94e-01 | 90.3% | 95.7% |
| 4394553 | 184.1.1.1 ↗ | alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Glycos_trans_3N | 0.63 | 50.0 | 4.72e-01 | 85.5% | 70.7% |
| 3609850 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.60 | 45.0 | 3.31e-01 | 88.7% | 84.9% |
| 3566449 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.60 | 48.0 | 4.15e-01 | 96.8% | 55.2% |
| 3279123 | 608.1.1.1 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD | 0.59 | 49.0 | 3.67e-01 | 96.8% | 61.7% |
| 3919218 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 46.0 | 2.85e-01 | 88.7% | 13.8% |
| 3994468 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.59 | 42.0 | 4.11e-01 | 75.8% | 91.4% |
| 1019363 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 47.0 | 3.86e-01 | 87.1% | 75.4% |
| 4405928 | 5086.1.1.196 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX | 0.59 | 44.0 | 4.28e-01 | 79.0% | 78.6% |
| 3864142 | 109.4.1.1778 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_GCN1 | 0.59 | 46.0 | 3.11e-01 | 88.7% | 19.6% |
| 3645753 | 109.4.1.1426 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, HEAT_2, ARM_PUB | 0.58 | 45.0 | 3.03e-01 | 91.9% | 20.0% |
| 143968 | 109.4.1.137 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Type_III_YscG | 0.58 | 41.0 | 4.38e-01 | 82.3% | 88.7% |
| 4930625 | 2.1.1.95 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Lig_C | 0.57 | 42.0 | 3.32e-01 | 79.0% | 45.2% |
| 3732397 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.57 | 41.0 | 3.40e-01 | 79.0% | 100.0% |
| 3356720 | 109.4.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm | 0.56 | 45.0 | 2.78e-01 | 91.9% | 31.4% |
| 3580368 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.55 | 47.0 | 3.65e-01 | 100.0% | 41.4% |
| 3781427 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.54 | 47.0 | 3.76e-01 | 96.8% | 54.4% |
| 5017266 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.54 | 41.0 | 3.80e-01 | 82.3% | 90.0% |
D2
medium
residues 70-152
Domain cluster:
rep: IMGVR_UViG_3300048114_000341-3300048114-Ga0494428_0000018_19163_19501__D12-87