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IMGVR_UViG_3300025393_000009-3300025393-Ga0208041_10008187
Arc-VirIMGVR_UViG_3300025393_000009-3300025393-Ga0208041_10008187
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-111
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.76 | 64.0 | 5.91e-01 | 90.6% | 89.6% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.76 | 55.0 | 4.81e-01 | 74.5% | 97.4% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 56.0 | 5.07e-01 | 77.4% | 66.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.76 | 63.0 | 5.01e-01 | 91.5% | 63.6% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.75 | 62.0 | 5.83e-01 | 89.6% | 88.5% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.75 | 62.0 | 6.03e-01 | 89.6% | 90.8% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.74 | 61.0 | 5.70e-01 | 89.6% | 87.2% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.73 | 52.0 | 5.77e-01 | 76.4% | 95.2% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.71 | 57.0 | 5.64e-01 | 87.7% | 92.9% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.70 | 58.0 | 5.73e-01 | 90.6% | 94.7% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.70 | 50.0 | 5.60e-01 | 90.6% | 98.8% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.69 | 57.0 | 4.84e-01 | 91.5% | 70.1% |
| 2af0A02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.69 | 48.0 | 5.43e-01 | 91.5% | 96.2% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 52.0 | 4.17e-01 | 79.2% | 66.8% |
| 1rp3G02 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.67 | 51.0 | 4.67e-01 | 80.2% | 97.9% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 61.0 | 5.71e-01 | 98.1% | 89.8% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.67 | 50.0 | 4.86e-01 | 77.4% | 79.3% |
| 3c8gD00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 55.0 | 4.82e-01 | 89.6% | 100.0% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.67 | 56.0 | 5.62e-01 | 91.5% | 100.0% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.66 | 55.0 | 5.33e-01 | 91.5% | 95.8% |
| 2j0wA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.66 | 52.0 | 5.54e-01 | 84.0% | 95.7% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 53.0 | 5.14e-01 | 87.7% | 96.7% |
| 2cdqA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.66 | 52.0 | 5.38e-01 | 84.0% | 95.9% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 46.0 | 4.14e-01 | 74.5% | 86.8% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.65 | 55.0 | 5.35e-01 | 95.3% | 91.6% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.62 | 50.0 | 5.12e-01 | 91.5% | 93.0% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.61 | 45.0 | 4.35e-01 | 76.4% | 78.6% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 49.0 | 3.68e-01 | 89.6% | 74.9% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 49.0 | 4.56e-01 | 91.5% | 93.8% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 45.0 | 4.03e-01 | 86.8% | 80.5% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.56 | 47.0 | 3.80e-01 | 91.5% | 55.9% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.55 | 45.0 | 3.69e-01 | 85.8% | 78.7% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 39.0 | 4.38e-01 | 74.5% | 96.5% |
| 1txuA02 | 1.20.1050.80 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain | 0.54 | 43.0 | 3.77e-01 | 84.9% | 63.1% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.54 | 44.0 | 4.52e-01 | 92.5% | 99.0% |
| 8jpdG01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.54 | 46.0 | 4.15e-01 | 95.3% | 68.3% |
| 2eh3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 41.0 | 3.97e-01 | 82.1% | 88.5% |
| 8h6rA01 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.53 | 36.0 | 3.99e-01 | 76.4% | 85.9% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 3.69e-01 | 90.6% | 81.6% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.53 | 42.0 | 3.56e-01 | 92.5% | 76.2% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.53 | 42.0 | 3.56e-01 | 90.6% | 59.5% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.52 | 40.0 | 4.13e-01 | 84.0% | 98.1% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 36.0 | 3.41e-01 | 74.5% | 67.2% |
| 1vw4L01 | 3.90.1030.10 | Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 | 0.51 | 38.0 | 3.55e-01 | 80.2% | 80.7% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5005610 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.88 | 77.0 | 8.00e-01 | 94.3% | 99.0% |
| 3989535 | 632.6.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit | 0.82 | 60.0 | 6.32e-01 | 75.5% | 84.2% |
| 4648665 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.80 | 55.0 | 6.06e-01 | 75.5% | 87.1% |
| 4237257 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.79 | 57.0 | 6.10e-01 | 74.5% | 86.7% |
| 3459621 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.79 | 57.0 | 5.86e-01 | 74.5% | 86.0% |
| 5031855 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.77 | 54.0 | 6.12e-01 | 75.5% | 95.0% |
| 1147365 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.77 | 65.0 | 6.02e-01 | 91.5% | 84.3% |
| 3385577 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.76 | 64.0 | 5.97e-01 | 90.6% | 86.9% |
| 3967229 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.76 | 63.0 | 5.59e-01 | 89.6% | 75.2% |
| 3595205 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.76 | 55.0 | 4.22e-01 | 74.5% | 36.4% |
| 4981575 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.76 | 64.0 | 5.86e-01 | 90.6% | 85.2% |
| 1549356 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.75 | 62.0 | 5.83e-01 | 89.6% | 88.5% |
| 3853606 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.75 | 62.0 | 6.00e-01 | 89.6% | 89.2% |
| 3914530 | 601.39.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 › Serine_rich | 0.75 | 64.0 | 5.53e-01 | 93.4% | 89.1% |
| 3449442 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.74 | 55.0 | 5.55e-01 | 77.4% | 93.3% |
| 4979116 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.71 | 50.0 | 4.92e-01 | 73.6% | 80.0% |
| 3796999 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.70 | 55.0 | 5.63e-01 | 83.0% | 92.0% |
| 3972132 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.69 | 57.0 | 5.21e-01 | 91.5% | 75.2% |
| 5005588 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.69 | 49.0 | 3.97e-01 | 72.6% | 84.1% |
| 3249525 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 57.0 | 5.14e-01 | 90.6% | 95.2% |
| 5049088 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.68 | 57.0 | 5.64e-01 | 91.5% | 88.2% |
| 4333411 | 601.18.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › CYP38_PsbQ-like | 0.67 | 55.0 | 5.17e-01 | 89.6% | 79.2% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 56.0 | 5.17e-01 | 91.5% | 84.4% |
| 4370662 | 601.2.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_B562 | 0.66 | 53.0 | 5.45e-01 | 86.8% | 100.0% |
| 3980115 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.65 | 53.0 | 4.89e-01 | 90.6% | 92.3% |
| 3586819 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.65 | 53.0 | 4.61e-01 | 89.6% | 67.1% |
| 3411249 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 48.0 | 4.52e-01 | 78.3% | 74.6% |
| 3925326 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.65 | 55.0 | 4.71e-01 | 93.4% | 64.1% |
| 3686609 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.64 | 48.0 | 5.11e-01 | 77.4% | 91.1% |
| 4483437 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.64 | 54.0 | 5.12e-01 | 93.4% | 77.7% |
| 4502437 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.64 | 54.0 | 5.18e-01 | 91.5% | 80.8% |
| 4018342 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.64 | 51.0 | 5.10e-01 | 91.5% | 84.5% |
| 3974204 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 51.0 | 4.98e-01 | 91.5% | 92.5% |
| 3927684 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.62 | 49.0 | 4.36e-01 | 85.8% | 91.6% |
| 3442429 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 39.0 | 3.16e-01 | 72.6% | 50.3% |
| 3516162 | 603.1.1.23 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 | 0.54 | 45.0 | 3.88e-01 | 90.6% | 74.1% |
| 5031064 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.53 | 40.0 | 4.16e-01 | 82.1% | 85.0% |
| 3771070 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.52 | 43.0 | 3.77e-01 | 87.7% | 65.2% |
| 4623646 | 2004.1.1.480 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 | 0.50 | 42.0 | 2.82e-01 | 90.6% | 47.2% |