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IMGVR_UViG_3300025546_000142-3300025546-Ga0209225_10013472

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300025546_000142-3300025546-Ga0209225_10013472 ↗
Kingdom:: archaea

Quality

86.6 mean pLDDT

Cluster

View cluster (11 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 15-152

PDB

Domain cluster: representative

CATH (27)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4r5qA00	3.90.320.10	Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A ›	0.80	48.0	4.10e-01	81.9%	38.6%
3ijmA00	3.90.1570.20	Alpha Beta › Alpha-Beta Complex › tt1808, chain A ›	0.75	61.0	5.96e-01	100.0%	79.5%
4ic1D00	3.90.320.10	Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A ›	0.70	52.0	4.47e-01	81.9%	51.0%
1y88A01	3.40.1350.10	Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 ›	0.68	56.0	5.89e-01	94.2%	95.2%
3devA02	3.10.310.30	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 ›	0.65	48.0	5.24e-01	84.8%	91.4%
3syyA00	3.90.320.10	Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A ›	0.63	48.0	4.31e-01	82.6%	57.2%
2qx2A00	3.10.570.10	Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain	0.63	54.0	4.11e-01	92.8%	75.8%
6ll8A02	3.10.310.20	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain	0.60	47.0	5.06e-01	100.0%	95.8%
1ym5A02	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.60	48.0	4.61e-01	85.5%	98.7%
2x3eA01	3.40.47.10	Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase	0.59	39.0	3.67e-01	86.2%	55.0%
1i74A02	3.10.310.20	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain	0.58	47.0	5.07e-01	100.0%	100.0%
1ah5A03	3.30.160.40	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain	0.57	32.0	3.93e-01	99.3%	87.2%
4htgA03	3.30.160.40	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain	0.56	32.0	3.99e-01	100.0%	96.2%
4r80A00	3.10.450.630	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.56	29.0	3.74e-01	83.3%	88.2%
3tqmA00	3.30.160.100	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like	0.56	32.0	3.77e-01	100.0%	83.3%
1xubA02	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.55	44.0	4.35e-01	85.5%	98.0%
3n2qA02	3.30.300.190	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 ›	0.54	40.0	4.35e-01	77.5%	99.1%
8gjaD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	46.0	3.74e-01	93.5%	83.7%
5dwzC01	3.40.47.10	Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase	0.53	38.0	3.40e-01	83.3%	53.2%
1atnD00	3.60.10.10	Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase	0.53	47.0	3.88e-01	99.3%	97.7%
7r8iA01	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.53	43.0	3.74e-01	88.4%	88.0%
3dnsA00	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.53	36.0	3.73e-01	70.3%	87.0%
3oq3B02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.52	28.0	3.18e-01	82.6%	67.0%
6l4lA02	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.52	43.0	4.33e-01	86.2%	98.5%
2vosA02	3.90.190.20	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain	0.52	40.0	4.00e-01	99.3%	77.6%
2amhA00	3.90.950.10	Alpha Beta › Alpha-Beta Complex › Maf protein ›	0.52	47.0	4.17e-01	99.3%	94.4%
1u8sA01	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.50	27.0	3.30e-01	76.8%	82.6%

ECOD (81)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5013697	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.83	48.0	4.50e-01	82.6%	48.5%
5027476	2008.1.1.17 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF559	0.82	57.0	6.72e-01	100.0%	98.0%
5075190	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.80	50.0	4.72e-01	82.6%	53.8%
4991917	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.74	60.0	6.03e-01	100.0%	83.6%
5057415	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.74	51.0	5.88e-01	100.0%	97.0%
3509755	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.73	57.0	5.58e-01	98.6%	74.7%
4411889	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.73	57.0	4.83e-01	97.8%	51.4%
3506045	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.73	52.0	4.69e-01	88.4%	55.1%
5035773	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.72	58.0	5.73e-01	97.8%	80.0%
5027583	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.72	50.0	5.72e-01	97.1%	94.3%
4995749	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.72	53.0	5.92e-01	100.0%	96.3%
4960251	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.72	59.0	6.01e-01	100.0%	89.5%
5057713	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.72	60.0	6.20e-01	100.0%	94.5%
5072204	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.71	53.0	5.87e-01	98.6%	98.2%
5074941	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.71	54.0	5.98e-01	100.0%	100.0%
3605286	2008.2.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like	0.70	47.0	5.40e-01	82.6%	94.0%
4604110	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.70	56.0	5.08e-01	97.1%	63.9%
4940995	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	52.0	5.78e-01	99.3%	97.3%
3274159	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	51.0	5.54e-01	84.1%	91.3%
4209016	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	55.0	4.60e-01	97.8%	50.0%
4928402	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	55.0	5.94e-01	98.6%	100.0%
3838750	2008.1.1.59 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1	0.69	53.0	5.25e-01	79.7%	93.8%
3723708	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	59.0	5.23e-01	100.0%	64.9%
4940727	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	46.0	5.26e-01	96.4%	93.0%
4043610	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.68	51.0	4.18e-01	78.3%	54.4%
3270711	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.68	54.0	5.56e-01	96.4%	87.7%
4999640	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.68	53.0	4.61e-01	81.9%	61.4%
4928680	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.68	43.0	3.84e-01	81.9%	45.8%
4983302	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.68	59.0	5.91e-01	100.0%	91.4%
4402765	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.68	58.0	6.03e-01	100.0%	98.4%
4941691	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.67	57.0	5.49e-01	98.6%	80.5%
5073133	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.67	60.0	5.84e-01	100.0%	87.3%
4947569	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.67	58.0	5.59e-01	99.3%	82.6%
3945442	2008.1.1.50 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ	0.66	50.0	4.39e-01	83.3%	53.2%
4432991	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.66	54.0	3.96e-01	87.0%	56.5%
4979146	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.66	59.0	5.57e-01	98.6%	81.2%
4928308	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.66	62.0	4.24e-01	100.0%	52.5%
5057728	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.66	55.0	5.77e-01	98.6%	97.6%
4955488	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.66	44.0	4.82e-01	82.6%	84.5%
2715553	2008.1.1.34 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Card1_endonuc	0.65	54.0	5.73e-01	91.3%	99.2%
5076295	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.65	59.0	5.96e-01	99.3%	98.5%
4933915	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.65	57.0	5.44e-01	100.0%	80.6%
4956304	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.65	58.0	5.08e-01	100.0%	65.5%
3387933	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.65	61.0	5.24e-01	100.0%	72.4%
3602674	2008.1.1.114 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143	0.65	46.0	5.25e-01	87.7%	100.0%
4998336	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.65	59.0	5.79e-01	100.0%	91.7%
4970960	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.65	59.0	5.68e-01	100.0%	86.5%
4193221	7502.1.1.1 ↗	a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HGTP_anticodon	0.65	42.0	4.67e-01	98.6%	82.4%
4977513	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.65	58.0	5.54e-01	94.9%	83.9%
5071081	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.65	58.0	5.56e-01	94.9%	85.2%
4948814	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.64	57.0	5.39e-01	93.5%	83.1%
4975459	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.64	59.0	5.72e-01	99.3%	89.7%
4962492	2008.1.1.234 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF26437	0.64	56.0	5.09e-01	95.7%	84.3%
5079137	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.63	58.0	5.80e-01	99.3%	96.4%
4040973	330.4.1.1 ↗	a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC	0.63	32.0	4.32e-01	94.9%	94.3%
4998161	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.63	59.0	5.70e-01	100.0%	95.5%
4983658	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.63	56.0	5.55e-01	94.9%	90.3%
5035312	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.63	46.0	5.21e-01	97.8%	100.0%
5049500	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.63	57.0	5.60e-01	98.6%	97.3%
3716928	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.63	58.0	5.20e-01	100.0%	78.3%
3591893	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.62	58.0	5.42e-01	100.0%	90.9%
4946865	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.62	47.0	5.15e-01	94.9%	100.0%
4359254	330.4.1.1 ↗	a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC	0.62	34.0	4.39e-01	99.3%	97.3%
4958435	2008.1.1.96 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RmuC	0.61	57.0	4.70e-01	100.0%	66.0%
4552605	330.4.1.1 ↗	a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC	0.61	33.0	4.30e-01	97.8%	93.6%
4351693	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.60	47.0	5.14e-01	100.0%	99.1%
164523	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.60	48.0	5.10e-01	100.0%	95.9%
4628389	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.60	48.0	5.11e-01	100.0%	96.7%
4926971	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.60	51.0	4.90e-01	97.1%	80.6%
2599880	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.60	47.0	5.06e-01	100.0%	95.8%
4046444	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.60	53.0	4.82e-01	94.9%	85.0%
4630823	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.59	45.0	4.87e-01	79.7%	97.4%
4968040	2008.1.1.235 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF26618	0.59	50.0	5.21e-01	95.7%	97.7%
4558929	330.4.1.1 ↗	a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC	0.58	32.0	3.97e-01	100.0%	91.3%
4033230	2008.1.1.155 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › CoiA_nuc	0.57	53.0	5.25e-01	100.0%	94.5%
3476615	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.54	32.0	4.03e-01	95.7%	100.0%
4882261	2008.1.1.27 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAI1	0.54	43.0	3.20e-01	86.2%	36.6%
4180585	7520.1.1.1 ↗	a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like › CinA	0.54	43.0	4.21e-01	99.3%	79.3%
3691245	2008.1.1.27 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAI1	0.53	43.0	3.54e-01	86.2%	52.5%
3689598	2003.1.5.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DNA_methylase	0.53	48.0	3.32e-01	99.3%	77.4%
3546715	5104.1.1.3 ↗	a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2	0.52	46.0	4.61e-01	100.0%	95.7%

D2 high residues 162-299

PDB

Domain cluster: representative

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4hstB03	1.10.1400.10	Mainly Alpha › Orthogonal Bundle › Penicillin amidase (Acylase) alpha subunit, N-terminal domain › Aminohydrolase, alpha-helical knob region	0.60	33.0	3.41e-01	94.9%	55.0%
1b8dA00	1.10.490.20	Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins	0.56	40.0	3.80e-01	100.0%	62.2%
2bk9A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.54	41.0	3.97e-01	92.8%	71.2%
2ef8A00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.54	32.0	3.95e-01	94.9%	96.4%
4u04A02	1.10.3290.10	Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain	0.52	37.0	3.24e-01	74.6%	72.5%
2mx8A01	1.10.274.70	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain	0.52	35.0	3.82e-01	99.3%	83.2%
7dluA01	1.10.287.1260	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.52	30.0	3.38e-01	85.5%	73.3%
3q9oA02	3.90.1350.10	Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain	0.52	42.0	3.99e-01	97.1%	71.9%
6wk3A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.52	37.0	3.66e-01	97.8%	70.3%
4q5qB00	1.20.1050.130	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.51	35.0	3.15e-01	95.7%	50.0%
2v7fA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.50	40.0	4.03e-01	97.8%	85.6%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5075077	3962.1.1.0 ↗	alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit	0.80	75.0	6.86e-01	99.3%	84.6%
4932254	3962.1.1.0 ↗	alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit	0.77	71.0	6.99e-01	98.6%	99.3%
4018666	7023.1.1.3 ↗	alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT_2	0.57	35.0	3.51e-01	75.4%	58.6%
4441061	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.53	30.0	3.60e-01	76.8%	81.1%
3719502	5001.1.1.53 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › LMBR1	0.52	42.0	3.30e-01	87.7%	73.4%
3827908	101.1.17.2 ↗	alpha arrays › HTH › HTH › FF domain › FF	0.51	40.0	3.89e-01	85.5%	74.2%

D3 medium residues 300-318_339-444_466-477

PDB

Domain cluster: rep: IMGVR_UViG_2619619116_000001-2619619116-2620725375__D325-427

CATH (63)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ri5A00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.83	46.0	3.65e-01	86.1%	30.2%
2p35A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.82	43.0	3.91e-01	86.1%	40.2%
2nxcA03	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.82	43.0	4.17e-01	86.1%	46.4%
5bxyA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.82	45.0	4.29e-01	86.1%	48.1%
4kigA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.81	45.0	4.10e-01	82.5%	42.7%
2esrA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.81	46.0	4.31e-01	86.1%	48.1%
3ajdA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.80	47.0	4.11e-01	86.1%	41.2%
1zq9A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.80	43.0	3.92e-01	86.1%	40.6%
3gu3A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.80	46.0	4.27e-01	86.1%	47.3%
3htxD03	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.76	46.0	3.86e-01	86.1%	37.6%
3jwhA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.76	45.0	3.97e-01	86.1%	42.4%
1sqgA04	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.73	46.0	4.03e-01	94.9%	44.4%
3ll7A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.72	45.0	3.98e-01	94.9%	45.3%
2yx1A03	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.70	48.0	4.36e-01	97.8%	53.3%
3k0bA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	52.0	4.77e-01	97.8%	60.1%
4fsdA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	55.0	4.50e-01	98.5%	47.9%
3v97A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	46.0	4.26e-01	92.0%	55.0%
1jsxA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	50.0	4.41e-01	99.3%	52.8%
2py6A03	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	48.0	4.31e-01	86.1%	53.3%
3mb5A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.68	50.0	4.41e-01	98.5%	53.4%
1l3iA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.68	49.0	4.39e-01	97.8%	55.1%
5h02A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.68	46.0	4.13e-01	92.0%	52.8%
8k1fC01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.68	49.0	4.32e-01	98.5%	52.6%
2okcA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.67	63.0	4.73e-01	99.3%	56.9%
3ufbA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.67	61.0	4.53e-01	100.0%	40.9%
4m37A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.67	48.0	4.77e-01	90.5%	70.3%
3c3pA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.67	51.0	4.47e-01	97.8%	55.1%
1d2gA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.66	45.0	3.98e-01	94.9%	50.0%
3duwA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.66	53.0	4.49e-01	100.0%	52.5%
3c0kA03	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.65	52.0	4.38e-01	97.8%	52.3%
1xoiA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.65	53.0	3.58e-01	85.4%	87.8%
2ar0A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.65	53.0	3.97e-01	86.1%	44.2%
3fpfA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.65	46.0	3.68e-01	100.0%	38.3%
3s1sA02	3.40.50.12420	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.64	59.0	4.08e-01	100.0%	32.7%
4dcmA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.64	49.0	4.41e-01	100.0%	58.9%
1nv8A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.64	48.0	4.16e-01	97.8%	53.3%
2hnkA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.63	54.0	4.50e-01	98.5%	54.6%
1suiA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.62	50.0	4.21e-01	97.8%	51.5%
2yqzA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.62	44.0	3.87e-01	91.2%	51.3%
1i1nA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.62	52.0	4.36e-01	97.8%	54.5%
2pbfA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.60	53.0	4.54e-01	97.8%	59.6%
1dl5A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.59	51.0	4.43e-01	98.5%	61.7%
1xu9C00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.57	43.0	3.53e-01	80.3%	63.2%
3c8mA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.56	35.0	3.34e-01	83.9%	51.8%
2g95B02	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	41.0	3.38e-01	78.8%	45.5%
3h5dA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	44.0	3.44e-01	86.1%	76.8%
1oaaA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.55	43.0	3.51e-01	83.2%	62.2%
6tg6A01	3.40.1360.10	Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 ›	0.54	34.0	3.77e-01	78.1%	80.8%
1bqgA02	3.20.20.120	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain	0.54	43.0	3.45e-01	83.2%	86.5%
6jh7B00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.54	42.0	3.41e-01	81.8%	59.8%
4p98A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.53	35.0	3.52e-01	77.4%	64.6%
3lf2A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.53	41.0	3.44e-01	83.2%	63.5%
1lucB00	3.20.20.30	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain	0.53	43.0	3.24e-01	86.1%	86.3%
1ne2B00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.53	43.0	3.87e-01	97.8%	63.9%
3qy9B01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	35.0	3.56e-01	80.3%	68.4%
2qtlA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.52	38.0	3.69e-01	83.9%	67.7%
3vc1J00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.52	46.0	3.56e-01	97.1%	46.4%
3igsB00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.51	41.0	3.46e-01	85.4%	66.4%
3do5A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.51	35.0	3.24e-01	83.9%	54.0%
2h00B00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	47.0	4.02e-01	97.8%	71.0%
4htfA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.50	39.0	3.26e-01	82.5%	59.0%
3h2bB00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.50	34.0	3.08e-01	81.8%	49.0%
3rosA01	3.40.605.10	Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1	0.50	46.0	3.66e-01	100.0%	64.6%

ECOD (85)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4999846	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.86	64.0	4.83e-01	94.9%	37.5%
5053796	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.83	57.0	4.20e-01	86.1%	30.0%
None	—		0.83	54.0	4.02e-01	86.1%	28.9%
3838101	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.81	58.0	4.41e-01	86.1%	34.8%
4974136	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.80	57.0	4.15e-01	86.1%	30.5%
5031875	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.80	77.0	5.42e-01	100.0%	38.9%
4926848	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.78	62.0	4.57e-01	86.1%	35.2%
4976856	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.78	67.0	5.08e-01	89.1%	48.3%
3981664	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.78	71.0	4.85e-01	95.6%	62.4%
4997329	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.77	60.0	4.36e-01	86.1%	33.3%
3590009	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.77	64.0	4.59e-01	86.9%	52.4%
4256965	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	64.0	4.41e-01	86.9%	50.0%
4117483	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.76	55.0	5.09e-01	86.1%	60.6%
5046165	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	72.0	5.00e-01	100.0%	51.5%
4336036	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	63.0	4.54e-01	86.1%	43.8%
4974764	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.76	63.0	4.58e-01	86.1%	41.5%
4941122	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	64.0	4.62e-01	88.3%	52.6%
4276326	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	59.0	4.41e-01	86.1%	37.0%
5080533	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	62.0	4.48e-01	86.1%	49.3%
3602826	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.75	69.0	4.92e-01	97.1%	59.7%
4999203	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.75	62.0	4.36e-01	86.1%	39.7%
5051401	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	62.0	4.59e-01	86.1%	47.0%
5046632	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	70.0	4.90e-01	100.0%	60.8%
5075147	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	62.0	4.70e-01	86.1%	45.6%
4961865	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	66.0	4.51e-01	94.9%	49.3%
5005190	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	62.0	4.48e-01	88.3%	55.8%
4959285	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	70.0	5.10e-01	100.0%	45.8%
5045466	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	69.0	4.73e-01	100.0%	49.4%
4979845	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.73	60.0	4.47e-01	86.1%	43.8%
5076056	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.72	62.0	4.68e-01	89.1%	44.7%
1687152	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.72	61.0	4.41e-01	88.3%	44.3%
None	—		0.71	54.0	4.18e-01	92.7%	38.9%
4418049	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.70	66.0	4.72e-01	100.0%	55.4%
5044197	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.70	64.0	4.68e-01	95.6%	42.1%
3571921	2003.1.5.82 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31	0.70	52.0	3.76e-01	97.8%	29.2%
3512225	2003.1.5.6 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F	0.70	44.0	4.61e-01	78.8%	69.6%
4563233	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.70	62.0	4.51e-01	93.4%	38.5%
3735754	2003.1.5.82 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31	0.70	52.0	3.95e-01	97.8%	35.9%
4155768	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.70	64.0	4.54e-01	95.6%	53.2%
None	—		0.69	59.0	4.30e-01	89.1%	48.8%
4964246	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.69	55.0	4.19e-01	88.3%	38.0%
4968431	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.69	49.0	3.88e-01	94.9%	38.8%
1002423	2003.1.5.42 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21	0.69	48.0	4.31e-01	86.1%	53.3%
4580141	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.69	64.0	5.30e-01	100.0%	91.9%
5051817	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.69	65.0	4.64e-01	100.0%	71.2%
3704924	2003.1.5.6 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F	0.69	50.0	3.74e-01	100.0%	33.4%
4271018	2003.1.5.53 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr	0.69	51.0	3.67e-01	97.8%	29.0%
3838952	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.68	57.0	4.16e-01	87.6%	42.4%
5042433	2003.1.5.4 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT	0.68	49.0	4.40e-01	99.3%	55.1%
3989299	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.68	61.0	4.22e-01	95.6%	35.3%
4946359	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.67	59.0	4.46e-01	92.7%	45.3%
4936070	2003.1.5.5 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020	0.67	51.0	4.48e-01	99.3%	56.6%
None	—		0.66	52.0	4.66e-01	99.3%	61.1%
3734967	2003.1.1.148 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR	0.66	43.0	3.27e-01	86.1%	28.4%
4490154	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.66	56.0	4.18e-01	89.1%	49.5%
2756680	2003.1.5.6 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F	0.66	49.0	3.61e-01	100.0%	30.6%
4998596	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.66	58.0	4.34e-01	92.7%	41.6%
4051182	2003.1.5.17 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_5	0.66	48.0	3.85e-01	92.0%	40.8%
3959678	2003.1.3.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain	0.66	37.0	4.28e-01	81.8%	76.0%
None	—		0.65	56.0	4.07e-01	89.8%	48.8%
4980807	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.65	51.0	4.40e-01	98.5%	54.6%
4950207	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.65	53.0	3.91e-01	86.1%	45.9%
185519	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.64	52.0	3.96e-01	90.5%	40.2%
4128384	2003.1.5.25 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB	0.64	51.0	4.37e-01	99.3%	54.8%
4303905	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.64	54.0	4.07e-01	89.1%	58.7%
4611556	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.64	50.0	3.67e-01	97.8%	32.8%
3686136	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.63	53.0	4.16e-01	100.0%	43.9%
3726570	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.63	53.0	4.14e-01	100.0%	43.9%
3783636	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.62	52.0	3.96e-01	97.8%	40.0%
None	—		0.62	53.0	4.01e-01	89.1%	54.2%
3605866	2003.1.5.156 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31	0.61	49.0	3.42e-01	100.0%	27.4%
3741064	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.58	51.0	4.02e-01	100.0%	47.0%
3391289	2003.1.5.156 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31	0.58	49.0	3.35e-01	97.8%	27.9%
3721118	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.58	44.0	3.40e-01	97.1%	37.2%
3606573	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.57	47.0	3.39e-01	100.0%	32.2%
3881325	2003.1.5.66 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11	0.57	53.0	4.03e-01	99.3%	56.7%
4648658	3008.1.1.0 ↗	a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.56	35.0	4.00e-01	92.0%	87.4%
4989004	2003.1.5.5 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020	0.55	50.0	4.31e-01	97.8%	81.3%
3610787	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.55	41.0	2.97e-01	78.8%	56.7%
3251467	2003.1.5.6 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F	0.54	51.0	3.68e-01	99.3%	52.6%
3697184	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.54	43.0	3.35e-01	84.7%	51.0%
None	—		0.53	49.0	3.65e-01	98.5%	60.3%
4110113	2003.1.5.4 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT	0.53	49.0	4.04e-01	99.3%	67.5%
None	—		0.53	49.0	3.64e-01	99.3%	58.5%
3689209	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.53	41.0	3.19e-01	82.5%	58.1%

D4 medium residues 319-338_478-490_525-657

PDB

Domain cluster: representative

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2okcA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.80	75.0	5.98e-01	99.4%	93.1%
3s1sA02	3.40.50.12420	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.79	74.0	5.39e-01	98.2%	72.2%
2ar0A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.79	74.0	5.78e-01	98.8%	98.8%
3ufbA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.79	74.0	5.82e-01	100.0%	93.2%
3khkA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.78	70.0	5.50e-01	93.4%	94.0%
3lkdA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.78	73.0	6.01e-01	99.4%	100.0%
2f8lA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.75	58.0	5.02e-01	78.9%	98.3%
1g38A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.72	63.0	5.60e-01	91.0%	100.0%
2dulA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.57	47.0	3.81e-01	86.1%	95.8%
1zwxA00	3.60.10.10	Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase	0.57	42.0	3.48e-01	75.3%	96.5%
4h0nA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.56	41.0	3.95e-01	75.9%	96.4%

ECOD (93)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4999203	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.92	78.0	5.68e-01	86.1%	100.0%
4999846	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.88	81.0	6.65e-01	95.2%	100.0%
5031875	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.86	80.0	6.00e-01	96.4%	80.8%
4941122	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.84	76.0	5.81e-01	94.0%	100.0%
4971638	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.83	78.0	5.75e-01	97.6%	76.6%
4276326	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.83	79.0	6.30e-01	99.4%	99.7%
4812692	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.83	61.0	5.37e-01	74.7%	100.0%
None	—		0.83	70.0	5.75e-01	87.3%	100.0%
4998596	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.83	62.0	4.88e-01	76.5%	98.4%
4999708	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.83	76.0	5.62e-01	95.8%	100.0%
4943682	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.83	73.0	6.30e-01	91.6%	100.0%
5065151	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.82	74.0	5.46e-01	94.6%	76.4%
4303905	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.81	77.0	6.10e-01	99.4%	95.4%
4997131	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.81	74.0	5.96e-01	95.8%	100.0%
5004543	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.80	62.0	4.84e-01	78.9%	82.2%
None	—		0.80	76.0	5.98e-01	100.0%	89.2%
5078789	4333.1.1.8 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › N6_Mtase	0.80	76.0	5.02e-01	100.0%	49.2%
4997329	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.80	74.0	5.72e-01	97.0%	99.7%
4964246	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.80	76.0	6.07e-01	100.0%	94.3%
4950207	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.80	76.0	5.82e-01	100.0%	89.7%
None	—		0.80	73.0	5.73e-01	95.8%	88.9%
5053796	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	74.0	5.76e-01	97.0%	100.0%
3839942	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.79	72.0	5.27e-01	94.0%	100.0%
185519	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	70.0	5.73e-01	92.8%	100.0%
3987620	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	74.0	5.79e-01	98.8%	88.0%
4955193	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	73.0	5.48e-01	96.4%	77.8%
4961865	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.79	75.0	5.36e-01	100.0%	88.0%
4563233	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.79	75.0	5.81e-01	100.0%	84.2%
5021590	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	73.0	5.59e-01	97.6%	88.7%
2322907	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.79	75.0	5.80e-01	100.0%	88.8%
None	—		0.78	74.0	5.95e-01	100.0%	99.3%
None	—		0.78	75.0	6.15e-01	100.0%	100.0%
2785020	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.78	70.0	5.67e-01	94.0%	100.0%
5051817	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.78	75.0	5.58e-01	100.0%	94.0%
4336036	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.78	70.0	5.35e-01	94.0%	100.0%
4946359	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.78	70.0	5.55e-01	92.8%	100.0%
3987658	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.78	60.0	5.00e-01	78.9%	88.7%
4120064	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.77	71.0	5.86e-01	96.4%	93.8%
5051401	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.77	70.0	5.51e-01	94.6%	100.0%
5048596	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.77	73.0	5.97e-01	99.4%	100.0%
4974136	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.77	70.0	5.49e-01	95.8%	89.5%
None	—		0.77	70.0	5.39e-01	95.8%	97.4%
3838101	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.77	72.0	5.88e-01	100.0%	99.0%
4997523	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	68.0	4.79e-01	91.6%	100.0%
4946139	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	72.0	5.35e-01	97.6%	94.0%
2754732	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.76	73.0	5.62e-01	100.0%	91.6%
4969177	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.76	73.0	5.68e-01	99.4%	99.7%
4959285	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	73.0	5.67e-01	100.0%	90.2%
4976856	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.76	73.0	5.88e-01	99.4%	100.0%
3590009	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	70.0	5.27e-01	95.8%	98.0%
3957602	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.76	64.0	5.74e-01	88.6%	84.4%
4395671	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.76	70.0	5.93e-01	96.4%	98.8%
5053549	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	70.0	6.00e-01	95.8%	100.0%
4946596	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.76	72.0	5.63e-01	99.4%	97.2%
3950008	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.76	69.0	5.87e-01	95.8%	93.7%
3602826	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.76	70.0	5.25e-01	96.4%	96.7%
4979845	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.75	72.0	5.63e-01	99.4%	100.0%
1548119	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.75	58.0	5.04e-01	78.9%	99.2%
4565957	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.75	68.0	5.66e-01	94.0%	97.0%
4944007	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	72.0	5.54e-01	100.0%	99.4%
3388298	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	69.0	5.10e-01	95.2%	98.7%
4256965	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	71.0	5.17e-01	99.4%	92.4%
5046632	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	72.0	5.23e-01	100.0%	92.5%
3981664	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.75	71.0	5.11e-01	100.0%	97.2%
4155768	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.75	71.0	5.37e-01	99.4%	95.2%
3166401	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.75	71.0	6.14e-01	99.4%	100.0%
5045466	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	67.0	4.82e-01	94.0%	84.0%
4624804	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	71.0	5.71e-01	100.0%	92.2%
4948425	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.74	58.0	5.64e-01	80.1%	100.0%
None	—		0.74	68.0	5.41e-01	96.4%	99.0%
4100163	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	71.0	5.50e-01	100.0%	100.0%
5075147	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.74	65.0	5.25e-01	91.0%	100.0%
4954651	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	59.0	5.97e-01	83.1%	93.3%
5037827	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.73	69.0	5.72e-01	99.4%	98.9%
5076056	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	67.0	5.41e-01	96.4%	99.3%
4114757	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	69.0	5.49e-01	100.0%	98.1%
3838952	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	65.0	5.03e-01	94.0%	100.0%
3289055	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	69.0	5.61e-01	100.0%	97.6%
5046165	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	67.0	4.88e-01	95.8%	81.2%
3957880	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	69.0	5.92e-01	99.4%	97.1%
5049452	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.73	70.0	5.24e-01	100.0%	79.4%
4969011	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.73	66.0	5.12e-01	95.2%	95.2%
4930428	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.72	62.0	4.99e-01	88.6%	100.0%
4969967	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.72	64.0	4.93e-01	92.8%	100.0%
4380038	2003.1.5.160 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I	0.71	60.0	5.24e-01	87.3%	99.6%
4034596	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.71	59.0	4.74e-01	86.1%	77.7%
5080533	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.71	65.0	4.99e-01	97.0%	98.6%
4968431	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.70	67.0	5.66e-01	99.4%	100.0%
5044197	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.68	62.0	4.77e-01	94.0%	85.8%
3942265	2003.1.5.22 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase	0.67	60.0	5.02e-01	94.6%	85.2%
3838236	2003.1.5.62 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I	0.64	61.0	5.63e-01	99.4%	99.5%
3938460	2003.1.5.66 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11	0.58	53.0	4.62e-01	98.8%	98.0%
3858888	2003.1.5.81 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25	0.58	54.0	4.63e-01	98.8%	93.2%

D5 medium residues 658-682_805-970

PDB

Domain cluster: rep: IMGVR_UViG_3300025439_000107-3300025439-Ga0208323_10036613__D8-19_121-257

CATH (9)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2xubA05	6.10.140.1450	Special › Helix non-globular › Helix Hairpins ›	0.72	23.0	3.27e-01	100.0%	57.3%
2mtqA00	1.20.58.130	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.58	24.0	3.85e-01	96.3%	100.0%
3kreA01	3.30.200.20	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1	0.57	20.0	2.83e-01	74.3%	61.9%
1dj2A02	1.10.300.10	Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2	0.56	28.0	3.81e-01	95.3%	92.9%
1jm6B02	1.20.140.20	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain	0.54	31.0	3.43e-01	99.5%	68.8%
1vx7301	1.10.287.310	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.54	21.0	3.44e-01	96.3%	95.9%
4fqnC00	1.20.1160.20	Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) ›	0.54	22.0	3.35e-01	78.0%	88.2%
3ezhA00	1.20.120.960	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain	0.51	27.0	3.43e-01	78.5%	85.1%
1yo7A00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.50	29.0	3.64e-01	97.9%	91.7%

ECOD (38)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5078789	4333.1.1.8 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › N6_Mtase	0.89	80.0	5.42e-01	92.7%	49.4%
5001065	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.89	81.0	6.64e-01	94.8%	95.9%
5065152	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.88	80.0	6.59e-01	93.7%	97.1%
4999204	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.87	81.0	7.02e-01	95.8%	94.1%
4999847	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.87	79.0	6.53e-01	94.2%	100.0%
5031876	4333.1.1.6 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › M_Eco57I_C	0.80	74.0	6.28e-01	96.9%	98.6%
185520	4333.1.1.5 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › BpuSI_TRD	0.79	73.0	6.13e-01	96.9%	95.4%
4932256	4333.1.1.6 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › M_Eco57I_C	0.77	69.0	5.92e-01	93.7%	99.3%
3953725	4333.1.1.6 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › M_Eco57I_C	0.73	68.0	5.85e-01	97.4%	96.4%
4969968	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.73	63.0	5.31e-01	91.1%	98.7%
4586572	4333.1.1.6 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › M_Eco57I_C	0.73	59.0	5.32e-01	83.8%	100.0%
4968432	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.73	59.0	5.33e-01	84.3%	99.6%
5024595	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.72	63.0	5.21e-01	91.1%	95.6%
4079871	4333.1.1.6 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › M_Eco57I_C	0.72	65.0	5.70e-01	95.3%	97.1%
4946140	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.72	64.0	5.12e-01	92.1%	98.6%
4950296	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.72	63.0	5.32e-01	91.1%	98.6%
4969178	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.71	61.0	5.34e-01	89.5%	99.3%
4647178	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.71	63.0	5.20e-01	92.7%	100.0%
3839403	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.71	61.0	5.26e-01	89.5%	97.9%
4941123	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.71	61.0	5.33e-01	91.1%	99.3%
2785021	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.70	57.0	5.09e-01	84.3%	98.1%
3973577	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.70	52.0	3.99e-01	75.9%	98.5%
4948426	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.70	52.0	5.73e-01	76.4%	99.4%
5076057	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.70	64.0	5.94e-01	97.4%	97.9%
4276327	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.69	60.0	5.36e-01	91.1%	99.2%
5019577	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.68	56.0	4.59e-01	84.8%	88.6%
4656227	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.67	56.0	5.16e-01	87.4%	100.0%
5017975	4333.1.1.1 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › Methylase_S	0.66	52.0	4.08e-01	80.6%	100.0%
4964254	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.66	54.0	4.83e-01	85.9%	100.0%
5018196	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.66	52.0	3.95e-01	81.7%	96.0%
3965200	4333.1.1.1 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › Methylase_S	0.65	52.0	4.92e-01	82.2%	100.0%
4622610	101.1.1.431 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CFEM	0.63	25.0	4.03e-01	93.2%	100.0%
4598582	4333.1.1.1 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › Methylase_S	0.63	47.0	3.62e-01	75.4%	97.7%
3707921	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.57	30.0	3.91e-01	100.0%	89.1%
3782470	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.56	31.0	3.83e-01	100.0%	87.0%
3607681	633.10.1.15 ↗	alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17	0.52	32.0	3.79e-01	100.0%	88.1%
3485322	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.51	31.0	3.65e-01	100.0%	87.7%
3346738	109.4.1.1271 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24	0.50	26.0	2.89e-01	83.2%	60.0%

D6 medium residues 683-804

PDB

Domain cluster: representative

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ybyA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.62	32.0	4.20e-01	86.1%	92.2%
6bhdA03	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.62	29.0	4.04e-01	81.1%	88.9%
3a5zD02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.60	30.0	3.94e-01	82.0%	89.1%
2pm9A02	2.20.25.400	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.59	18.0	3.14e-01	77.9%	100.0%
1bkbA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.59	31.0	4.09e-01	86.1%	93.8%
2yztA00	3.30.160.250	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain ›	0.59	28.0	3.56e-01	74.6%	78.8%
1uebA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.59	30.0	4.13e-01	87.7%	96.8%
2eifA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.58	27.0	3.86e-01	82.0%	93.2%
3le4A00	2.20.70.10	Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; ›	0.57	25.0	3.50e-01	82.0%	85.5%
3go5A03	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.57	31.0	4.02e-01	77.9%	92.9%
4tyzA00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.54	30.0	3.21e-01	75.4%	58.7%
1z1bA01	3.30.160.60	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger	0.54	26.0	3.47e-01	70.5%	93.0%
2r7dA03	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.53	26.0	3.65e-01	82.0%	96.7%
2eczA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.52	26.0	3.29e-01	90.2%	81.4%
1wfqA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.52	31.0	3.91e-01	88.5%	100.0%
1y5oA00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.51	34.0	3.54e-01	75.4%	72.2%

ECOD (37)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5065152	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.74	69.0	5.04e-01	100.0%	40.3%
5001065	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.74	69.0	4.97e-01	100.0%	40.6%
5078789	4333.1.1.8 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › N6_Mtase	0.72	67.0	4.23e-01	100.0%	20.8%
4999847	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.68	63.0	4.62e-01	100.0%	41.6%
3570399	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.67	28.0	3.88e-01	76.2%	76.9%
4972486	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.65	30.0	4.51e-01	84.4%	100.0%
4252940	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.61	30.0	4.03e-01	81.1%	87.7%
4670334	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.61	30.0	4.04e-01	78.7%	89.2%
4434149	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.61	30.0	4.06e-01	82.0%	89.2%
4119533	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.61	29.0	4.04e-01	78.7%	93.3%
4066623	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.61	29.0	4.11e-01	81.1%	95.0%
5024595	4333.1.1.2 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C	0.60	55.0	4.04e-01	100.0%	46.6%
4946166	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.60	29.0	4.07e-01	84.4%	95.0%
4425795	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.60	29.0	3.99e-01	81.1%	89.2%
4032291	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.60	29.0	3.90e-01	81.1%	87.7%
4399115	2.1.1.13 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-5a	0.60	30.0	4.16e-01	85.2%	93.8%
4678731	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.60	30.0	3.98e-01	79.5%	89.2%
3914746	4.1.1.128 ↗	beta barrels › SH3 › SH3 › SH3 › Tudor_4	0.59	29.0	3.77e-01	80.3%	81.4%
4050524	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.59	29.0	3.92e-01	81.1%	89.2%
4043601	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.58	29.0	3.91e-01	81.1%	89.2%
3317544	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.58	30.0	3.99e-01	85.2%	92.3%
4168836	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.58	30.0	3.92e-01	85.2%	88.6%
4582456	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.57	30.0	3.80e-01	83.6%	87.1%
3948516	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.57	29.0	3.89e-01	70.5%	92.3%
4167626	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.57	29.0	3.87e-01	85.2%	92.3%
4494810	7502.1.1.0 ↗	a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS	0.57	30.0	3.58e-01	82.0%	76.2%
3742641	220.1.1.58 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › PH-GRAM_MTMR6-like	0.57	32.0	3.35e-01	74.6%	59.1%
4003604	220.1.1.0 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like	0.55	35.0	3.78e-01	71.3%	74.3%
4629022	4.1.1.238 ↗	beta barrels › SH3 › SH3 › SH3 › KOW5_SPT5	0.55	26.0	3.44e-01	80.3%	80.0%
4945673	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.55	28.0	3.80e-01	86.1%	95.3%
4198379	220.1.1.162 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › PF31014	0.53	42.0	3.84e-01	83.6%	85.0%
3600862	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.53	30.0	3.65e-01	79.5%	85.0%
3175483	220.1.1.9 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › Voldacs	0.53	42.0	3.66e-01	90.2%	54.3%
5001377	220.1.1.0 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like	0.52	28.0	3.28e-01	74.6%	72.9%
4886650	7502.1.1.0 ↗	a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS	0.52	29.0	3.36e-01	73.8%	76.5%
4036822	7502.1.1.0 ↗	a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS	0.52	27.0	3.20e-01	70.5%	71.8%
3222943	4161.1.1.0 ↗	beta complex topology › MOSC N-terminal domain-like › MOSC N-terminal domain-like › MOSC N-terminal domain-like	0.50	37.0	2.96e-01	95.1%	36.4%