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IMGVR_UViG_3300025644_000010-3300025644-Ga0209042_100064242

Arc-Vir

IMGVR_UViG_3300025644_000010-3300025644-Ga0209042_100064242

Quality

75.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 23-104
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.64 53.0 4.31e-01 93.9% 96.9%
2mh3A00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.62 35.0 3.72e-01 100.0% 62.9%
3l0oA01 1.10.720.10 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.61 36.0 4.29e-01 75.6% 98.0%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.59 39.0 3.79e-01 100.0% 60.4%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 47.0 4.10e-01 91.5% 90.0%
7t2rC01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.57 31.0 3.67e-01 96.3% 77.2%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.56 45.0 3.95e-01 91.5% 55.7%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.56 46.0 4.23e-01 93.9% 83.3%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.56 45.0 4.64e-01 87.8% 94.7%
1m9iA01 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.55 37.0 3.74e-01 97.6% 71.2%
3d7iB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.54 34.0 3.31e-01 98.8% 54.1%
2icwG01 1.20.120.390 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 0.54 43.0 3.74e-01 86.6% 96.0%
1eyvB00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.52 40.0 3.44e-01 82.9% 67.7%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3174241 109.4.1.224 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT1_CAF1_bind 0.71 50.0 3.57e-01 74.4% 50.4%
3925622 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.59 47.0 3.43e-01 87.8% 66.4%
3341235 109.46.1.1 alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH 0.56 46.0 4.05e-01 90.2% 91.2%
5049791 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.55 44.0 3.78e-01 90.2% 75.7%
3369650 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.55 44.0 3.67e-01 91.5% 48.7%
4937823 3558.1.1.0 alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain 0.52 40.0 3.80e-01 84.1% 83.0%
3251542 109.4.1.2301 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_6, TPR_16, TPR_19 0.51 31.0 3.03e-01 90.2% 51.6%
D2 medium residues 117-187
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3dsbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.70 52.0 4.66e-01 80.3% 87.1%
2ky4A01 1.10.3130.20 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › Phycobilisome linker domain 0.64 44.0 3.61e-01 71.8% 95.4%
3ilkA02 1.10.8.590 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.64 46.0 4.70e-01 77.5% 83.8%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 56.0 4.94e-01 100.0% 71.8%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 44.0 4.72e-01 76.1% 100.0%
5tk8A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.60 49.0 3.64e-01 93.0% 91.1%
3ejnA03 1.20.120.840 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain 0.57 46.0 4.07e-01 90.1% 69.4%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 44.0 3.60e-01 88.7% 76.6%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.56 39.0 3.23e-01 100.0% 41.6%
1v66A00 1.10.720.30 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain 0.55 41.0 4.23e-01 81.7% 95.4%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.54 38.0 2.84e-01 73.2% 29.6%
1khcA02 1.10.720.50 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › PWWP, helical domain 0.52 37.0 3.80e-01 78.9% 79.7%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 42.0 3.22e-01 100.0% 93.4%
2fiwA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 41.0 3.21e-01 90.1% 55.6%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3238458 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.72 60.0 4.05e-01 88.7% 65.3%
3938247 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 59.0 4.25e-01 93.0% 65.2%
331637 3435.1.1.1 a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › RdgC 0.71 46.0 2.98e-01 95.8% 15.4%
3963537 3435.1.1.1 a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › RdgC 0.70 45.0 2.94e-01 95.8% 15.7%
3607058 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.68 51.0 3.90e-01 80.3% 63.6%
5062284 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.66 51.0 4.29e-01 81.7% 78.3%
3989035 4230.1.1.3 alpha arrays › DnaD domain › DnaD domain › DnaD domain › DnaB_2 0.66 45.0 4.09e-01 70.4% 52.6%
4530474 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.65 58.0 5.57e-01 97.2% 92.5%
3477670 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.64 47.0 4.92e-01 97.2% 84.6%
3688424 2003.1.5.79 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.63 44.0 2.92e-01 100.0% 17.7%
3532830 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.63 44.0 4.41e-01 74.6% 73.3%
3722689 148.1.1.12 alpha arrays › Histone-like › Histone-related › Histone › Bromo_TP 0.63 43.0 3.64e-01 71.8% 100.0%
3330830 3238.1.1.1 alpha superhelices › Mitochondrial mTERF-like › Mitochondrial mTERF › Mitochondrial mTERF › mTERF 0.63 45.0 2.81e-01 76.1% 18.0%
1036939 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.62 56.0 5.15e-01 100.0% 81.3%
4930413 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.62 55.0 5.04e-01 100.0% 80.0%
3228862 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.62 42.0 4.28e-01 70.4% 77.1%
4938927 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.61 54.0 4.96e-01 100.0% 77.9%
4041102 3960.1.1.1 alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › AadA_C 0.58 41.0 3.67e-01 76.1% 75.2%
4078112 592.1.1.1 alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.57 47.0 4.62e-01 91.5% 96.2%
4963200 601.7.1.34 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 0.56 44.0 4.00e-01 100.0% 62.0%
3789516 592.1.1.1 alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.56 45.0 4.41e-01 90.1% 94.9%
3387670 3819.1.1.0 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.56 49.0 3.08e-01 98.6% 20.0%
2401680 3960.1.1.1 alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › AadA_C 0.55 40.0 3.51e-01 76.1% 73.8%
5073740 873.1.1.0 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.53 43.0 3.14e-01 90.1% 75.7%
3384417 185.1.1.1 alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl 0.52 37.0 3.44e-01 76.1% 95.7%
D3 medium residues 237-400
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03167.26 best UDG 37.0 5.10e-09 89.6% 90.0%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ui0A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.87 83.0 7.81e-01 100.0% 89.1%
6ajpA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.85 81.0 7.41e-01 100.0% 87.9%
2d3yA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.83 80.0 7.10e-01 100.0% 91.3%
1wywA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.79 72.0 6.49e-01 97.0% 81.9%
1mugA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.77 70.0 6.99e-01 95.1% 98.8%
2c2pA01 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.76 68.0 6.71e-01 93.3% 94.7%
1oe4A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.73 69.0 5.95e-01 100.0% 91.0%
7bovA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.61 51.0 4.80e-01 87.2% 98.5%
3pdiA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.61 45.0 4.68e-01 87.2% 81.8%
1zmbA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.60 48.0 4.21e-01 84.8% 91.5%
4ldaB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 41.0 4.63e-01 87.8% 90.6%
2q0xA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 54.0 4.48e-01 99.4% 94.4%
3g13B00 3.40.50.1390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Resolvase, N-terminal catalytic domain 0.59 40.0 4.37e-01 85.4% 81.9%
4l9aA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 52.0 4.37e-01 95.7% 93.8%
4eziA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.48e-01 100.0% 80.5%
5b5lA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.58 48.0 4.43e-01 87.8% 98.1%
3icvA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.38e-01 99.4% 78.8%
3lcrB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.45e-01 100.0% 88.1%
3o8oA03 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 48.0 4.36e-01 87.8% 79.1%
4ar9A01 3.40.30.160 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Collagenase ColT, N-terminal domain 0.57 40.0 4.32e-01 94.5% 83.1%
4m7xA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 31.0 4.08e-01 86.6% 96.7%
1sulB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 4.65e-01 92.7% 95.9%
6ejiA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.57 46.0 4.46e-01 86.0% 97.8%
1bvuA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.56 44.0 4.69e-01 84.1% 93.2%
1bho100 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.56 47.0 4.47e-01 87.2% 99.5%
3o8oF01 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 47.0 4.19e-01 87.8% 84.0%
5jd5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 51.0 4.13e-01 100.0% 77.6%
1fuiA01 3.40.50.1070 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 46.0 4.59e-01 88.4% 93.1%
1t5bB00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.56 46.0 4.32e-01 87.2% 100.0%
2xdqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.55 41.0 4.49e-01 92.1% 94.9%
6nbrC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.58e-01 87.2% 74.8%
3gpiA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.74e-01 87.8% 70.0%
3sggA02 3.20.20.490 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › GxGYxYP glycoside hydrolase, C-terminal domain 0.53 44.0 3.87e-01 90.9% 94.9%
4mcjG00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 43.0 4.50e-01 93.3% 94.2%
5f5nA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 43.0 3.60e-01 87.8% 66.1%
5ktkA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 44.0 3.25e-01 92.1% 52.4%
4ohxA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 39.0 3.54e-01 97.6% 56.6%
3e48A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 4.07e-01 86.6% 89.1%
1qe5A00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.51 46.0 3.98e-01 99.4% 98.1%
3l5aA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 44.0 3.42e-01 95.7% 76.1%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4352085 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.87 84.0 7.74e-01 100.0% 87.0%
3590878 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.87 83.0 7.54e-01 100.0% 92.9%
4968429 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 83.0 7.80e-01 100.0% 90.5%
4943408 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 82.0 7.63e-01 100.0% 86.0%
4962559 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 82.0 7.83e-01 100.0% 91.9%
4990486 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 82.0 7.70e-01 100.0% 91.6%
3057088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 81.0 7.31e-01 100.0% 84.2%
3386994 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 79.0 7.75e-01 99.4% 91.4%
4965816 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 81.0 7.42e-01 100.0% 90.7%
4937539 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 79.0 7.58e-01 100.0% 87.0%
4964719 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 81.0 7.48e-01 100.0% 89.0%
5021506 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 79.0 7.55e-01 100.0% 87.0%
3839117 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.82 75.0 7.28e-01 100.0% 88.3%
4964088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.81 77.0 7.23e-01 98.2% 89.5%
4318718 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.81 75.0 7.36e-01 98.8% 92.0%
3789320 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.80 74.0 6.58e-01 98.2% 98.7%
4019291 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.80 75.0 6.66e-01 99.4% 92.4%
3526630 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.79 73.0 6.45e-01 97.0% 78.7%
4449291 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.79 55.0 5.26e-01 88.4% 63.0%
3960892 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.78 72.0 6.80e-01 95.7% 86.3%
3287862 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.78 71.0 6.97e-01 95.7% 94.3%
5032364 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.77 69.0 6.39e-01 93.9% 97.5%
2070922 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.77 73.0 6.01e-01 100.0% 65.1%
4235738 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.77 68.0 6.91e-01 93.3% 100.0%
158456 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.76 70.0 6.70e-01 96.3% 90.7%
4999526 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.76 72.0 6.81e-01 100.0% 93.2%
3965875 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.75 68.0 6.92e-01 100.0% 98.1%
3395458 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.75 71.0 6.11e-01 100.0% 90.6%
5072275 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.72 66.0 6.31e-01 97.6% 98.4%
3728472 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.71 66.0 5.67e-01 100.0% 70.0%
3968560 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.66 56.0 5.86e-01 93.9% 98.7%
3784175 7579.1.1.53 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Say1_Mug180 0.61 55.0 4.05e-01 98.2% 78.9%
5047530 7569.1.1.2 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › DUF5591 0.61 53.0 5.42e-01 100.0% 97.4%
4988724 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 50.0 4.91e-01 87.2% 97.1%
3426929 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.60 49.0 4.20e-01 86.0% 98.1%
5058938 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 49.0 4.73e-01 84.1% 96.7%
4984198 2011.1.1.38 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › DUF2119 0.60 52.0 4.90e-01 93.3% 82.3%
4392347 7512.1.1.9 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › LpxB 0.59 49.0 4.70e-01 87.8% 100.0%
4971230 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.59 46.0 5.04e-01 94.5% 100.0%
3698340 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.59 54.0 4.27e-01 100.0% 93.9%
3387176 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 47.0 4.64e-01 84.1% 100.0%
5053299 7579.1.1.44 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.58 52.0 4.43e-01 95.7% 92.7%
5050245 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.58 40.0 4.53e-01 86.0% 94.2%
4444286 7579.1.1.53 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Say1_Mug180 0.58 53.0 4.01e-01 100.0% 70.6%
4538867 7579.1.1.36 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 0.57 52.0 3.89e-01 100.0% 68.3%
4058513 2007.1.14.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Oxidored_nitro 0.57 42.0 4.30e-01 86.6% 77.5%
4002575 2007.5.1.23 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › SGNH 0.57 52.0 4.47e-01 97.6% 89.2%
4593127 7589.1.1.2 a/b three-layered sandwiches › YgbK-like › YgbK-like › YgbK-like › NBD_C 0.57 47.0 4.63e-01 87.8% 94.9%
2813913 7579.1.1.10 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Thioesterase 0.57 51.0 4.34e-01 100.0% 83.3%
5007900 2007.1.5.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.55 50.0 4.73e-01 99.4% 99.5%
2527723 2007.12.1.0 a/b three-layered sandwiches › Flavodoxin-like › Beta-D-glucan exohydrolase, C-terminal domain › Beta-D-glucan exohydrolase, C-terminal domain 0.55 43.0 4.32e-01 86.6% 81.6%
3949778 2007.1.6.6 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain › Bac_GDH_CD 0.54 42.0 4.01e-01 81.1% 78.5%
4539530 2007.1.6.6 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain › Bac_GDH_CD 0.54 42.0 4.07e-01 81.1% 78.9%
5028771 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.54 49.0 4.20e-01 97.6% 84.3%
4564000 3273.1.1.7 alpha arrays › Filamentous archaeal viruses coat proteins › Filamentous archaeal viruses coat proteins › Filamentous archaeal viruses coat proteins › GDH_HM3 0.54 42.0 3.47e-01 81.7% 50.2%
3973742 101.1.2.669 alpha arrays › HTH › HTH › winged helix domain › Bac_GDH_CD 0.54 43.0 4.13e-01 83.5% 93.5%
4121749 2003.1.1.61 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR 0.54 45.0 3.78e-01 91.5% 76.2%
3960297 2003.1.1.61 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR 0.53 44.0 3.81e-01 90.2% 78.5%
2410571 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.53 40.0 4.30e-01 87.2% 93.4%
5082093 2002.3.1.0 a/b barrels › TIM beta/alpha-barrel › Glycoside hydrolase/deacetylase › Glycoside hydrolase/deacetylase 0.52 42.0 3.49e-01 86.6% 84.3%
4138936 2002.1.1.4 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Alpha-amylase 0.52 43.0 3.36e-01 89.0% 96.8%
4020791 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.52 43.0 4.10e-01 88.4% 94.9%
3595470 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 41.0 4.31e-01 87.2% 93.3%
5014144 2008.1.1.51 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC 0.50 44.0 4.21e-01 95.7% 100.0%
D4 medium residues 439-517
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gyiA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.71 38.0 3.54e-01 91.1% 41.8%
1jnrB02 6.20.260.10 Special › Other non-globular › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Adenylylsulphate reductase, beta subunit, C-terminal domain 0.66 35.0 3.50e-01 88.6% 48.2%
1b69A00 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.63 31.0 3.29e-01 72.2% 52.2%
4js8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 30.0 2.93e-01 73.4% 39.3%
1lomA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.59 34.0 3.16e-01 84.8% 43.6%
4emoC00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 30.0 2.64e-01 79.7% 34.5%
6zxfz01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 32.0 2.70e-01 87.3% 37.4%
1noyA01 3.30.342.10 Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 0.54 42.0 3.55e-01 84.8% 57.5%
1n02A00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.52 43.0 3.95e-01 89.9% 75.5%
2l2fA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.52 43.0 3.92e-01 91.1% 78.7%
3j7aF03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 28.0 3.00e-01 81.0% 56.3%
6az1E03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 29.0 3.00e-01 81.0% 56.9%
1reoA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 36.0 2.92e-01 73.4% 66.9%
1qhlA00 3.40.1140.10 Alpha Beta › 3-Layer(aba) Sandwich › N-terminal domain of mukB › 0.51 40.0 3.07e-01 88.6% 73.4%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2445318 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.70 33.0 4.31e-01 74.7% 94.3%
5054141 2.14.1.0 beta barrels › OB-fold › HupF/HypC-like › HupF/HypC-like 0.70 35.0 4.20e-01 81.0% 74.0%
4237578 2.4.1.2 beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.69 33.0 2.90e-01 72.2% 29.2%
5073475 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 56.0 3.77e-01 91.1% 31.3%
4068978 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.66 32.0 3.32e-01 75.9% 49.3%
5482 205.1.1.47 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4, APS-reductase_C, Fer4_7 0.66 35.0 2.86e-01 88.6% 26.8%
11143 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.65 55.0 3.56e-01 94.9% 20.5%
4888987 4.1.1.6 beta barrels › SH3 › SH3 › SH3 › KOW,40S_S4_C 0.60 31.0 3.32e-01 92.4% 55.1%
3398908 391.1.2.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related 0.58 40.0 4.24e-01 89.9% 81.4%
1178368 705.1.1.1 beta duplicates or obligate multimers › Cyanovirin-N › Cyanovirin-N › Cyanovirin-N › CVNH 0.58 34.0 3.90e-01 72.2% 84.9%
3281614 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.58 34.0 3.04e-01 77.2% 43.8%
4595815 325.1.7.3 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.57 37.0 4.10e-01 72.2% 81.5%
4099964 325.1.7.3 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.57 37.0 4.08e-01 72.2% 81.5%
4492087 325.1.7.3 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.55 36.0 3.95e-01 72.2% 81.5%
4964966 3504.3.1.1 beta barrels › MutM N-terminal domain-like › Fibrinogen binding protein N-terminal domain › Fibrinogen binding protein N-terminal domain › NFACT_N 0.54 38.0 3.00e-01 72.2% 81.9%
4581502 391.1.2.3 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › SVWC 0.53 33.0 3.47e-01 79.7% 68.0%
4236690 391.1.2.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related 0.52 34.0 3.53e-01 79.7% 71.6%
5022840 318.1.1.1 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.52 34.0 3.38e-01 72.2% 62.4%
3673266 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.51 27.0 2.69e-01 75.9% 47.1%