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IMGVR_UViG_3300025659_000317-3300025659-Ga0209249_10026724

Arc-Vir

IMGVR_UViG_3300025659_000317-3300025659-Ga0209249_10026724

Quality

93.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 14-170
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03167.26 best UDG 70.0 3.20e-19 94.9% 82.1%
D2 high residues 387-482
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 42.5 5.70e-11 97.9% 24.1%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.94 50.0 5.87e-01 100.0% 73.2%
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.92 88.0 8.21e-01 100.0% 84.3%
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.91 81.0 7.69e-01 100.0% 82.6%
1t7pA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.88 83.0 6.88e-01 100.0% 93.6%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.83 45.0 4.73e-01 99.0% 59.8%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 50.0 5.84e-01 100.0% 87.3%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.77 49.0 4.35e-01 99.0% 48.4%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.73 45.0 4.68e-01 100.0% 65.6%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 44.0 3.86e-01 100.0% 41.3%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.72 42.0 4.04e-01 100.0% 50.9%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.67 40.0 4.82e-01 99.0% 91.9%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 48.0 4.20e-01 100.0% 52.2%
2ks9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 47.0 3.09e-01 100.0% 19.8%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.65 37.0 3.55e-01 100.0% 47.3%
2yinA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.65 38.0 3.43e-01 100.0% 43.0%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.65 40.0 4.22e-01 97.9% 69.0%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.64 45.0 3.93e-01 100.0% 49.0%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 46.0 4.55e-01 100.0% 69.9%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 52.0 5.12e-01 100.0% 84.0%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 41.0 3.62e-01 100.0% 46.5%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.59 44.0 4.75e-01 97.9% 91.5%
3au3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 37.0 2.60e-01 99.0% 20.6%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 52.0 4.41e-01 100.0% 98.7%
6rv2A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 50.0 3.68e-01 96.9% 36.6%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 51.0 4.37e-01 100.0% 96.7%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 48.0 4.46e-01 97.9% 74.0%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 43.0 4.66e-01 99.0% 97.5%
2wb0X01 1.10.269.10 Mainly Alpha › Orthogonal Bundle › Adenovirus Single-stranded Dna-binding Protein, domain 1 › Adenovirus DNA-binding, N-terminal domain 0.55 40.0 3.84e-01 78.1% 96.6%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 40.0 3.90e-01 100.0% 70.0%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 36.0 3.59e-01 100.0% 65.0%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.54 46.0 3.76e-01 95.8% 94.6%
2pb2B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 39.0 3.44e-01 85.4% 54.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.51 44.0 4.16e-01 97.9% 99.1%
3f7cA00 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.50 44.0 3.54e-01 100.0% 49.2%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.50 42.0 3.83e-01 89.6% 86.5%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.94 90.0 5.48e-01 100.0% 19.8%
3964115 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.93 89.0 7.88e-01 100.0% 76.2%
2970331 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.92 85.0 6.71e-01 100.0% 52.8%
4061480 2484.1.1.58 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Taq-exonuc 0.92 87.0 5.78e-01 100.0% 29.7%
4072515 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.92 87.0 5.49e-01 100.0% 23.3%
3333792 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.92 87.0 6.93e-01 100.0% 56.6%
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 87.0 5.38e-01 100.0% 20.6%
1391185 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.91 87.0 6.76e-01 100.0% 52.4%
3676005 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.91 87.0 5.50e-01 100.0% 24.8%
57665 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.91 87.0 6.83e-01 100.0% 55.1%
4319500 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 87.0 5.31e-01 100.0% 20.4%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.90 86.0 5.42e-01 100.0% 25.1%
3505184 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 86.0 6.13e-01 100.0% 41.6%
4848449 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.90 80.0 7.43e-01 97.9% 76.9%
3616267 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 85.0 6.84e-01 100.0% 57.1%
3407160 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 79.0 6.60e-01 100.0% 58.7%
1503978 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 85.0 6.52e-01 100.0% 53.3%
3483300 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.89 84.0 6.20e-01 100.0% 54.1%
3211911 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.88 84.0 6.80e-01 100.0% 61.2%
3580212 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.87 82.0 8.31e-01 99.0% 100.0%
4622747 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.86 77.0 5.13e-01 100.0% 26.7%
4027632 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.83 77.0 7.03e-01 100.0% 78.3%
2810986 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.82 76.0 6.01e-01 100.0% 55.1%
3208746 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.75 43.0 3.29e-01 97.9% 26.2%
4996751 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.71 39.0 3.82e-01 97.9% 48.6%
3168467 109.4.1.623 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.67 46.0 3.36e-01 96.9% 26.7%
3723178 192.8.1.35 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 0.66 53.0 5.50e-01 100.0% 90.0%
3412603 3567.1.1.154 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PF30089 0.66 43.0 3.94e-01 99.0% 50.4%
4993505 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.66 48.0 4.47e-01 100.0% 60.8%
3725592 192.8.1.35 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 0.65 52.0 5.44e-01 100.0% 90.0%
3787647 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.64 38.0 3.78e-01 94.8% 56.0%
4028685 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 47.0 4.47e-01 100.0% 67.3%
3264172 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 42.0 4.24e-01 100.0% 69.5%
4026424 3758.1.1.104 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › PF30077 0.62 53.0 3.95e-01 96.9% 88.3%
2715279 174.1.1.2 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal 0.62 56.0 4.63e-01 100.0% 96.4%
3929433 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.61 47.0 4.48e-01 100.0% 70.0%
3954313 150.5.1.52 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE 0.60 44.0 4.50e-01 100.0% 76.8%
3397047 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 42.0 3.85e-01 97.9% 55.2%
3599875 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.60 56.0 4.87e-01 100.0% 72.1%
3692858 5086.1.1.174 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › AIM11_N 0.59 43.0 4.41e-01 100.0% 77.9%
5064040 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 51.0 3.82e-01 100.0% 42.4%
5050149 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.58 41.0 3.77e-01 99.0% 54.6%
3853953 601.1.2.53 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DGKD_4H 0.58 50.0 4.60e-01 93.8% 93.6%
3481371 2496.1.1.0 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like 0.57 48.0 3.58e-01 100.0% 39.5%
5031744 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.56 41.0 3.82e-01 92.7% 59.2%
3258401 101.1.2.281 alpha arrays › HTH › HTH › winged helix domain › Tfb2 0.53 43.0 3.69e-01 92.7% 86.5%
3642639 3922.1.1.269 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook 0.52 48.0 4.65e-01 100.0% 88.6%
4025072 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.51 48.0 4.44e-01 97.9% 87.0%
5065754 131.1.1.3 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD 0.50 45.0 3.31e-01 100.0% 37.6%
5029796 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 47.0 4.34e-01 99.0% 90.8%
D3 medium residues 177-287
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01612.27 best DNA_pol_A_exo1 28.1 2.30e-06 90.1% 35.3%
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.85 79.0 6.14e-01 97.3% 52.1%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.82 70.0 5.71e-01 97.3% 52.1%
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 75.0 5.59e-01 100.0% 43.5%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 74.0 5.43e-01 100.0% 40.8%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 74.0 5.33e-01 100.0% 38.2%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 74.0 5.49e-01 96.4% 45.6%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 74.0 6.12e-01 100.0% 58.6%
7jw6A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 74.0 5.86e-01 100.0% 54.4%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 73.0 5.81e-01 98.2% 54.8%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 73.0 5.89e-01 100.0% 60.0%
7pbkA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 65.0 5.08e-01 99.1% 44.1%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 70.0 5.26e-01 96.4% 72.6%
2qxfA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 58.0 4.74e-01 79.3% 66.7%
3cymA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.73 67.0 5.40e-01 100.0% 53.1%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.63 40.0 4.78e-01 70.3% 98.6%
1yvuA04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.55 41.0 3.32e-01 77.5% 46.7%
4nswA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 38.0 3.90e-01 73.9% 80.7%
2qkbA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 40.0 3.62e-01 78.4% 79.6%
6n9aB02 3.30.420.200 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.52 31.0 3.76e-01 82.9% 94.2%
4p4tA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 40.0 2.90e-01 82.9% 51.6%
2pz0B00 3.20.20.190 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase 0.51 44.0 3.50e-01 97.3% 52.7%
5wzeA01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.51 45.0 3.95e-01 100.0% 90.8%
3bzcA03 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.51 37.0 3.61e-01 77.5% 100.0%
1a8uA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 44.0 3.37e-01 100.0% 79.1%
4pv4A01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.50 44.0 3.89e-01 100.0% 92.4%
1gymA00 3.20.20.190 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase 0.50 44.0 3.31e-01 100.0% 39.9%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4622747 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.90 73.0 4.93e-01 97.3% 27.0%
3965745 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 83.0 6.01e-01 100.0% 42.5%
3266621 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 81.0 6.93e-01 97.3% 81.2%
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 81.0 5.10e-01 98.2% 23.3%
4037090 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.86 82.0 6.35e-01 100.0% 52.7%
4233346 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 80.0 5.50e-01 98.2% 33.6%
3980678 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 81.0 5.55e-01 100.0% 34.9%
4165451 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.85 80.0 6.02e-01 100.0% 45.7%
3778350 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 77.0 5.65e-01 100.0% 40.8%
3165932 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 75.0 5.87e-01 100.0% 48.4%
3892440 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.83 76.0 5.75e-01 97.3% 50.6%
3407164 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.83 77.0 5.96e-01 98.2% 53.2%
3661219 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 76.0 5.83e-01 100.0% 47.6%
3705325 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 78.0 5.66e-01 100.0% 41.5%
3434621 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 74.0 5.36e-01 100.0% 37.9%
3388110 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.82 77.0 5.32e-01 100.0% 34.8%
3993770 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 74.0 5.36e-01 100.0% 38.2%
1756776 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 73.0 5.22e-01 100.0% 35.9%
3600259 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 74.0 4.78e-01 100.0% 24.3%
1187764 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 74.0 5.44e-01 100.0% 40.8%
3261268 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.81 75.0 4.97e-01 97.3% 31.4%
3185973 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 74.0 5.36e-01 100.0% 38.0%
2469642 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 70.0 5.52e-01 97.3% 48.3%
4329924 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 77.0 5.75e-01 100.0% 45.3%
4333172 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 74.0 5.94e-01 100.0% 54.0%
3193711 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 74.0 5.63e-01 97.3% 47.2%
2725515 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 75.0 5.86e-01 100.0% 54.8%
4821686 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 71.0 7.11e-01 94.6% 100.0%
3435062 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 74.0 5.83e-01 100.0% 54.5%
3685910 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 75.0 5.88e-01 100.0% 57.7%
3818775 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 74.0 5.82e-01 100.0% 54.1%
3360497 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 74.0 6.00e-01 100.0% 59.5%
2704792 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 74.0 5.77e-01 100.0% 51.8%
3456683 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 75.0 5.91e-01 100.0% 58.6%
3591717 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 62.0 4.97e-01 83.8% 45.0%
3798192 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 75.0 5.72e-01 100.0% 51.3%
3937354 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 75.0 5.73e-01 100.0% 52.6%
4028087 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 74.0 5.76e-01 98.2% 52.6%
3961715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 72.0 6.01e-01 100.0% 60.0%
160349 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 74.0 6.01e-01 100.0% 57.7%
2117499 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 74.0 5.92e-01 100.0% 60.5%
11148 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 73.0 5.89e-01 100.0% 60.0%
3580193 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 72.0 5.78e-01 100.0% 55.1%
3922908 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 72.0 5.59e-01 100.0% 50.4%
3839957 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.77 71.0 4.93e-01 100.0% 32.4%
3656569 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 72.0 5.74e-01 100.0% 53.3%
3664145 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 72.0 5.78e-01 100.0% 59.5%
3445126 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 72.0 5.77e-01 100.0% 59.0%
3937660 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 72.0 5.31e-01 100.0% 46.4%
3357118 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 72.0 5.81e-01 100.0% 59.0%
3342017 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 71.0 5.73e-01 100.0% 55.6%
3440342 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 57.0 5.68e-01 78.4% 74.8%
3830378 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 71.0 5.79e-01 100.0% 61.3%
3510945 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 70.0 5.59e-01 100.0% 58.1%
4173211 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.75 70.0 4.88e-01 100.0% 34.5%
5081301 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.74 56.0 3.77e-01 78.4% 29.7%
3428835 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.74 68.0 5.24e-01 100.0% 67.9%
4291004 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.74 68.0 4.87e-01 100.0% 37.0%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.73 65.0 4.35e-01 96.4% 36.6%
3766382 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.73 64.0 4.82e-01 94.6% 58.4%
3515806 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 61.0 5.62e-01 99.1% 71.9%
4259073 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 64.0 4.86e-01 94.6% 44.2%
4522778 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 64.0 5.15e-01 94.6% 53.0%
4985600 896.1.1.0 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.60 40.0 4.64e-01 74.8% 93.8%
3730113 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 41.0 2.64e-01 82.9% 33.7%
None 0.53 40.0 2.61e-01 82.9% 30.3%
1401775 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 40.0 2.90e-01 82.9% 51.6%
3366423 6108.1.1.11 alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Dynamin_N 0.52 40.0 2.54e-01 84.7% 27.9%
4429421 2484.1.1.199 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut 0.51 43.0 3.22e-01 93.7% 36.3%
3913349 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 43.0 2.94e-01 93.7% 30.1%
3958663 2484.1.1.199 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut 0.51 43.0 3.70e-01 92.8% 60.0%
3726094 2002.1.1.20 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PI-PLC-Y,PI-PLC-X 0.51 44.0 3.32e-01 97.3% 43.4%
D4 medium residues 288-386
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3cymA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 75.0 5.68e-01 98.0% 44.9%
3a7kB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 50.0 3.69e-01 85.9% 71.3%
3itfA00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 54.0 5.23e-01 98.0% 98.2%
2yqrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.60 45.0 4.44e-01 77.8% 92.2%
2g7rA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.60 39.0 4.17e-01 99.0% 76.7%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 42.0 3.84e-01 76.8% 61.7%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.58 42.0 3.91e-01 78.8% 60.2%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.54 39.0 3.42e-01 76.8% 79.0%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.54 38.0 2.55e-01 72.7% 88.1%
2yviA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.54 34.0 3.52e-01 89.9% 68.5%
3r8eA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 40.0 3.47e-01 81.8% 95.0%
2dlaA01 1.20.930.50 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.53 44.0 3.80e-01 92.9% 89.4%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 40.0 3.55e-01 84.8% 55.3%
2wmoA01 1.25.40.410 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A 0.51 36.0 3.31e-01 73.7% 83.6%
1eo0A00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.50 27.0 3.03e-01 75.8% 63.6%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4283243 2004.1.1.149 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SecA_DEAD 0.62 52.0 3.61e-01 91.9% 63.5%
3943870 3711.1.1.1 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ 0.61 51.0 5.07e-01 92.9% 99.0%
3977695 3711.1.1.1 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ 0.60 53.0 4.99e-01 99.0% 94.2%
3763765 2484.1.1.42 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_2 0.60 45.0 2.75e-01 79.8% 34.7%
3838012 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.59 43.0 4.04e-01 76.8% 76.0%
4367207 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.59 47.0 4.64e-01 85.9% 86.7%
3298752 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.55 35.0 3.40e-01 74.7% 55.7%
3468013 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.54 35.0 3.52e-01 72.7% 63.0%
3726923 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.51 36.0 3.36e-01 74.7% 97.7%
D5 medium residues 515-543_675-794
PDB
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.82 57.0 6.30e-01 82.6% 86.1%
4x0qA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.77 63.0 6.51e-01 89.3% 88.8%
2ia0B02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.76 42.0 5.08e-01 89.3% 80.8%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 53.0 6.12e-01 87.2% 100.0%
1ab8A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.71 60.0 5.63e-01 87.9% 91.5%
4lowA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.71 37.0 4.77e-01 77.9% 88.1%
4mt1A07 3.30.70.1440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.71 47.0 5.59e-01 88.6% 98.0%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.71 58.0 5.23e-01 85.9% 90.4%
2wz1B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.70 59.0 5.38e-01 89.9% 93.9%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 46.0 5.55e-01 88.6% 100.0%
5oyhD00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 57.0 5.27e-01 86.6% 93.5%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 57.0 5.25e-01 87.2% 92.6%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.69 47.0 5.33e-01 87.2% 92.9%
5yuyA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 52.0 5.73e-01 88.6% 96.7%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.68 55.0 5.61e-01 85.2% 100.0%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.67 39.0 4.97e-01 87.2% 98.9%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.66 49.0 5.16e-01 76.5% 89.6%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.66 46.0 4.45e-01 70.5% 90.9%
4urgA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 53.0 5.38e-01 85.2% 99.3%
3tvkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 58.0 5.59e-01 96.6% 94.8%
1x7vA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 42.0 5.07e-01 88.6% 98.0%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.65 47.0 5.04e-01 73.8% 91.5%
3pjxA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 57.0 5.36e-01 94.6% 90.6%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.65 38.0 4.68e-01 85.2% 90.4%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.65 39.0 4.86e-01 70.5% 100.0%
4dpoB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 42.0 5.01e-01 89.9% 97.0%
3gqcC01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 51.0 5.36e-01 87.9% 90.5%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 49.0 5.36e-01 82.6% 97.5%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 51.0 5.43e-01 87.9% 94.7%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 55.0 5.60e-01 93.3% 100.0%
4hl9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 40.0 4.88e-01 86.6% 100.0%
3mcsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 47.0 4.19e-01 77.9% 92.6%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 58.0 5.64e-01 99.3% 95.7%
6hbzA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 55.0 5.39e-01 93.3% 93.7%
5xgbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 57.0 5.37e-01 98.7% 92.7%
3hvaA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 55.0 5.39e-01 94.6% 100.0%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.63 52.0 5.00e-01 88.6% 90.7%
4iobA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 56.0 5.52e-01 97.3% 96.3%
4zmuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 54.0 5.33e-01 93.3% 98.1%
3hvwA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 55.0 5.46e-01 97.3% 96.2%
4yjmC00 3.30.1390.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L7/L12, C-terminal domain/Adaptor protein ClpS 0.62 35.0 4.41e-01 87.9% 96.4%
3f44A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.13e-01 77.9% 93.8%
1tr0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 42.0 4.90e-01 89.3% 98.1%
1q2lA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.61 49.0 4.20e-01 83.2% 79.6%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 45.0 4.63e-01 96.6% 79.2%
2hkeA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.61 43.0 3.88e-01 70.5% 97.4%
1q2lA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 48.0 4.21e-01 85.2% 88.6%
1hr6A01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 45.0 4.00e-01 77.9% 87.4%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.60 39.0 4.50e-01 85.9% 92.5%
6hciB00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 33.0 3.96e-01 86.6% 80.8%
3bb5A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 40.0 4.74e-01 87.9% 100.0%
3e3xA01 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.59 42.0 4.71e-01 77.2% 95.6%
3fotA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.54 45.0 3.81e-01 89.9% 84.1%
4uw2B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.52 42.0 4.37e-01 84.6% 93.6%
2rkvA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 43.0 3.82e-01 88.6% 93.0%
ECOD (74)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4003030 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.87 55.0 6.86e-01 70.5% 100.0%
3613455 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.83 64.0 6.67e-01 79.2% 100.0%
3766383 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.83 59.0 6.57e-01 72.5% 100.0%
4115602 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.83 57.0 6.39e-01 70.5% 100.0%
3598488 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.82 59.0 5.76e-01 73.2% 100.0%
3962170 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 57.0 6.63e-01 71.8% 100.0%
3423771 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.80 57.0 6.27e-01 73.2% 100.0%
3638055 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.79 63.0 5.73e-01 83.9% 96.4%
3783788 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.78 63.0 4.83e-01 83.2% 98.0%
3289139 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.78 54.0 6.16e-01 71.1% 100.0%
3486431 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.76 62.0 4.73e-01 84.6% 99.0%
3706910 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.75 64.0 5.74e-01 89.9% 100.0%
3591785 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 64.0 6.39e-01 89.3% 93.3%
3407163 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.74 57.0 6.37e-01 79.2% 100.0%
3608339 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.74 62.0 6.52e-01 87.2% 100.0%
3625482 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.73 50.0 5.86e-01 87.9% 98.1%
3386929 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 54.0 5.41e-01 77.2% 87.1%
3790536 3122.1.1.1 a+b complex topology › MESD › MESD › MESD › Mesd 0.72 43.0 5.13e-01 73.8% 87.0%
4027647 3122.1.1.0 a+b complex topology › MESD › MESD › MESD 0.72 45.0 5.04e-01 76.5% 80.9%
4968297 304.4.1.2 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.71 41.0 5.30e-01 87.9% 100.0%
4215083 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.70 55.0 5.85e-01 98.7% 94.6%
4429067 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 62.0 5.90e-01 95.3% 92.4%
4932448 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.69 42.0 5.28e-01 87.9% 100.0%
4056579 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.69 42.0 5.25e-01 87.2% 100.0%
4611955 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.69 56.0 5.02e-01 85.9% 85.4%
4141589 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.69 51.0 5.43e-01 87.9% 87.7%
4210141 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.69 51.0 5.63e-01 88.6% 95.8%
4132191 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.68 52.0 5.66e-01 87.2% 94.4%
4025907 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.68 58.0 4.55e-01 89.9% 71.7%
3947751 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.68 56.0 4.89e-01 87.9% 70.7%
3945961 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.67 61.0 5.90e-01 97.3% 99.4%
3883719 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 56.0 3.78e-01 87.9% 28.4%
None 0.67 57.0 4.77e-01 89.3% 71.4%
3210215 325.1.5.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Ribosomal protein L10e 0.67 43.0 4.62e-01 72.5% 75.8%
3959182 304.48.1.41 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF2652 0.67 56.0 5.14e-01 87.9% 94.7%
3286133 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.67 55.0 5.39e-01 87.2% 93.8%
5062216 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 47.0 4.90e-01 72.5% 95.7%
3957787 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.66 56.0 4.98e-01 89.3% 81.4%
3597230 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 56.0 3.78e-01 89.3% 37.2%
3593319 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 54.0 5.03e-01 85.9% 85.9%
3263205 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.66 52.0 4.87e-01 90.6% 67.8%
3280378 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 58.0 5.59e-01 94.0% 100.0%
3286580 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.65 43.0 5.13e-01 71.8% 100.0%
3604040 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.65 43.0 4.51e-01 70.5% 73.9%
3973496 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.64 58.0 5.65e-01 98.7% 100.0%
3605466 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.64 52.0 4.62e-01 91.9% 59.5%
4373656 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.64 42.0 4.72e-01 70.5% 85.2%
4943031 304.28.1.38 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › CAA_C 0.64 49.0 4.60e-01 80.5% 90.3%
3284094 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.64 58.0 5.61e-01 98.7% 100.0%
4194780 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.64 53.0 3.89e-01 88.6% 66.2%
3485236 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 53.0 5.51e-01 87.9% 99.3%
3974428 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.63 57.0 5.50e-01 96.6% 100.0%
4269564 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.63 56.0 5.31e-01 97.3% 91.1%
4975729 304.48.1.112 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › SatD 0.63 52.0 5.42e-01 88.6% 94.8%
3281981 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.63 57.0 5.55e-01 99.3% 99.4%
4443100 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.62 52.0 3.88e-01 88.6% 70.8%
4552979 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 47.0 4.64e-01 79.2% 96.2%
3966559 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.62 54.0 5.27e-01 94.6% 97.0%
3599389 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 52.0 4.62e-01 89.3% 97.6%
5041147 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 52.0 5.43e-01 87.9% 98.5%
3280039 2002.5.1.0 a/b barrels › TIM beta/alpha-barrel › EAL domain › EAL domain 0.62 56.0 3.97e-01 98.7% 37.5%
3186517 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.62 50.0 4.55e-01 86.6% 94.0%
3952615 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.61 54.0 5.17e-01 96.6% 92.6%
3967644 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.61 55.0 5.39e-01 98.7% 99.4%
3291429 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 53.0 5.24e-01 94.0% 93.1%
3900562 304.110.1.7 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › TEX47 0.60 45.0 4.20e-01 79.2% 100.0%
3619798 3122.1.1.1 a+b complex topology › MESD › MESD › MESD › Mesd 0.60 43.0 4.63e-01 74.5% 89.2%
5082469 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.59 49.0 3.78e-01 88.6% 67.7%
4008806 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 51.0 4.87e-01 94.0% 82.9%
2512867 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.59 37.0 4.17e-01 89.3% 80.9%
3961696 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.58 50.0 5.07e-01 93.3% 100.0%
3961033 304.154.1.1 a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain › GGDEF_2 0.58 50.0 4.93e-01 93.3% 95.0%
3600563 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.58 50.0 4.39e-01 91.9% 62.3%
3941779 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.57 43.0 4.12e-01 79.9% 78.3%
D6 medium residues 544-674
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 84.6 9.90e-24 96.2% 30.7%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4dsfA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.89 68.0 7.42e-01 100.0% 92.7%
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.88 83.0 8.04e-01 100.0% 93.8%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.87 82.0 7.50e-01 99.2% 96.4%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.78 74.0 7.15e-01 100.0% 94.4%
7pbkB02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.77 71.0 7.04e-01 98.5% 96.3%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.76 72.0 6.94e-01 100.0% 94.4%
2j5oA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 32.0 4.52e-01 77.9% 96.9%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 36.0 4.10e-01 94.7% 81.9%
4rocA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 36.0 4.01e-01 94.7% 77.7%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.53 35.0 3.79e-01 75.6% 82.1%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3969341 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.92 81.0 8.31e-01 90.8% 99.2%
4456463 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.92 83.0 8.37e-01 93.9% 97.7%
4975020 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.92 80.0 7.89e-01 89.3% 88.9%
3711347 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 88.0 8.56e-01 100.0% 95.7%
4169333 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 82.0 8.38e-01 93.1% 100.0%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 87.0 8.46e-01 100.0% 97.9%
3562851 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 86.0 8.28e-01 100.0% 95.2%
4876668 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.90 78.0 8.06e-01 90.1% 99.2%
3595356 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.90 81.0 8.29e-01 93.1% 100.0%
4617703 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 78.0 7.63e-01 90.1% 99.3%
3386797 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 86.0 6.94e-01 100.0% 58.5%
4027630 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 79.0 8.30e-01 92.4% 100.0%
3483301 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.89 84.0 7.95e-01 99.2% 99.3%
3259994 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 83.0 8.35e-01 99.2% 98.5%
3001792 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.89 77.0 8.18e-01 90.8% 100.0%
3277186 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 75.0 7.67e-01 88.5% 100.0%
4024558 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 80.0 7.86e-01 100.0% 90.0%
2579554 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 83.0 7.89e-01 99.2% 91.2%
3654151 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 82.0 7.54e-01 99.2% 97.6%
4217329 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 76.0 7.96e-01 90.8% 100.0%
3595646 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 82.0 7.67e-01 100.0% 98.7%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.85 75.0 7.83e-01 90.8% 100.0%
3704770 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.84 72.0 7.30e-01 90.1% 100.0%
3601930 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.84 78.0 6.86e-01 99.2% 94.1%
3423772 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.84 67.0 7.16e-01 83.2% 100.0%
3703169 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.83 73.0 6.81e-01 93.1% 99.4%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.80 76.0 7.34e-01 100.0% 95.1%
3581048 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 75.0 7.06e-01 100.0% 87.7%
4848450 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.79 72.0 7.06e-01 96.9% 95.0%
4995740 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.73 61.0 6.25e-01 87.8% 100.0%
3793393 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 40.0 4.82e-01 96.9% 98.8%
3880943 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.63 36.0 4.17e-01 71.0% 76.8%
3905704 101.1.10.41 alpha arrays › HTH › HTH › Cyclin-like › HTH_Tnp_4 0.62 36.0 4.12e-01 71.0% 77.9%
5037039 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.61 42.0 4.37e-01 80.9% 73.6%
5028151 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 38.0 4.59e-01 95.4% 96.5%
3449999 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.60 37.0 3.79e-01 95.4% 62.3%
3787293 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.60 36.0 3.67e-01 94.7% 60.8%
3289370 101.1.1.300 alpha arrays › HTH › HTH › Three-helical HTH › HTH_30 0.59 36.0 4.06e-01 72.5% 79.0%
4999627 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.59 35.0 3.51e-01 70.2% 55.6%
3280686 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.59 36.0 4.10e-01 72.5% 81.0%
3687567 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.58 44.0 4.36e-01 79.4% 82.1%
3890040 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.58 35.0 3.51e-01 96.9% 55.7%
5064400 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.58 35.0 4.06e-01 73.3% 83.2%
5026540 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.58 35.0 3.86e-01 96.9% 74.3%
3655226 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.58 37.0 3.70e-01 95.4% 61.5%
3273891 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.58 35.0 3.67e-01 70.2% 65.0%
5076381 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.57 35.0 3.91e-01 96.9% 79.0%
4994316 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.57 34.0 3.34e-01 70.2% 52.9%
3282047 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.57 38.0 4.24e-01 71.0% 87.0%
4084282 101.1.1.31 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 0.55 31.0 3.79e-01 71.0% 85.9%
3620215 101.1.1.35 alpha arrays › HTH › HTH › Three-helical HTH › HTH_psq 0.55 41.0 3.61e-01 93.9% 53.2%
3185992 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.52 37.0 3.67e-01 72.5% 94.8%
3901577 101.1.1.113 alpha arrays › HTH › HTH › Three-helical HTH › DDE_Tnp_4 0.51 43.0 4.10e-01 93.9% 84.4%
4946927 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.50 39.0 3.36e-01 84.7% 87.1%