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IMGVR_UViG_3300025727_000271-3300025727-Ga0209047_10067061

Arc-Vir

IMGVR_UViG_3300025727_000271-3300025727-Ga0209047_10067061

Quality

67.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-69
PDB
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3n8bA00 3.10.450.700 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.68 54.0 5.24e-01 100.0% 77.3%
5tkyA04 2.60.34.10 Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › Substrate Binding Domain Of DNAk; Chain A, domain 1 0.63 50.0 4.26e-01 88.2% 79.3%
2gr7A00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.63 50.0 4.39e-01 98.5% 58.4%
3k7cA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 42.0 3.68e-01 91.2% 44.4%
1wznA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.62 46.0 4.91e-01 89.7% 94.6%
2oq8A00 2.60.40.2930 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 53.0 4.12e-01 95.6% 88.7%
2lyxA00 3.10.450.390 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Protein of unknown function DUF3889 0.62 49.0 4.54e-01 97.1% 66.7%
3g0kA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 45.0 3.75e-01 97.1% 43.8%
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.60 44.0 4.09e-01 97.1% 60.7%
3d2lA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.59 41.0 4.28e-01 94.1% 79.4%
3k0zA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 45.0 3.61e-01 85.3% 95.3%
1bdgA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 39.0 2.97e-01 85.3% 28.7%
7rd0A02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.58 51.0 3.32e-01 100.0% 76.1%
5w8mA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.58 50.0 3.63e-01 97.1% 100.0%
2ehbD00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.58 42.0 3.50e-01 98.5% 42.1%
4k08A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 45.0 3.62e-01 94.1% 41.0%
2kigA00 2.30.29.110 Mainly Beta › Roll › PH-domain like › 0.58 42.0 3.23e-01 77.9% 87.0%
4k3yC00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.57 49.0 3.15e-01 98.5% 86.2%
4ggtB00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.57 44.0 3.81e-01 100.0% 53.8%
3bxoA02 2.20.130.10 Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › CAC2371-like domains 0.57 41.0 4.35e-01 94.1% 88.1%
3uizB00 2.60.40.1570 Mainly Beta › Sandwich › Immunoglobulin-like › Dr adhesin 0.57 41.0 3.37e-01 79.4% 78.4%
3qvsA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.57 39.0 3.50e-01 73.5% 83.2%
4dj3B01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 46.0 4.00e-01 94.1% 62.2%
1h2iA01 3.30.390.80 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › DNA repair protein Rad52/59/22 0.56 47.0 3.80e-01 100.0% 54.7%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 3.30e-01 94.1% 84.5%
3cinA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.56 40.0 3.50e-01 76.5% 83.7%
2in5A00 2.40.360.10 Mainly Beta › Beta Barrel › YmcC-like fold › YmcC-like 0.55 46.0 3.45e-01 98.5% 39.0%
4ec6A00 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 42.0 3.71e-01 95.6% 53.2%
5icuA00 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 41.0 3.63e-01 80.9% 69.6%
1gr0A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.55 40.0 3.80e-01 79.4% 78.6%
2l4vA00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 46.0 3.78e-01 97.1% 82.2%
3ke7B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 43.0 3.57e-01 98.5% 46.6%
4eg9A00 2.50.20.40 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › 0.54 46.0 3.26e-01 97.1% 30.3%
4id2A00 2.40.128.510 Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4738 0.54 45.0 3.61e-01 92.6% 52.9%
3n72A00 3.15.10.20 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Activator of Hsp90 ATPase Aha1, N-terminal domain 0.54 45.0 3.58e-01 97.1% 44.8%
2p7sA00 3.10.130.10 Alpha Beta › Roll › P-30 Protein › Ribonuclease A-like domain 0.54 42.0 3.67e-01 88.2% 72.7%
5irbA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 39.0 3.47e-01 79.4% 65.4%
3q34A00 2.40.128.110 Mainly Beta › Beta Barrel › Lipocalin › Lipid/polyisoprenoid-binding, YceI-like 0.53 44.0 3.43e-01 100.0% 50.6%
3ub1D02 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 40.0 3.46e-01 94.1% 50.0%
3gvzA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.53 44.0 3.09e-01 98.5% 26.2%
4jguA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 3.46e-01 77.9% 56.8%
3vskA03 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.53 43.0 2.84e-01 98.5% 74.9%
1tuhA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 42.0 3.54e-01 98.5% 48.9%
2k54A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 43.0 3.65e-01 95.6% 53.7%
3grdA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 42.0 3.51e-01 98.5% 49.2%
2pwwA00 3.30.310.100 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › YugN-like 0.52 44.0 3.72e-01 95.6% 60.0%
3dmcA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 39.0 3.31e-01 97.1% 44.8%
7c5yA02 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 39.0 3.13e-01 92.6% 38.6%
3g8zA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 40.0 3.39e-01 97.1% 48.4%
3anzC00 2.70.240.10 Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA 0.51 44.0 2.94e-01 98.5% 75.2%
4kz1A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.51 41.0 3.41e-01 94.1% 54.1%
2vqeE01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 39.0 4.03e-01 97.1% 92.2%
3uc2A00 2.60.40.3340 Mainly Beta › Sandwich › Immunoglobulin-like › Domain of unknown function DUF4426 0.51 43.0 3.60e-01 98.5% 76.6%
1rm6B02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.50 38.0 3.29e-01 97.1% 51.4%
6zj8D01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.50 44.0 3.74e-01 100.0% 61.4%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3597976 2484.8.1.0 mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) 0.70 58.0 4.12e-01 92.6% 51.2%
3064463 6107.1.1.1 a+b two layers › a+b domain in platelet binding protein GspB › a+b domain in platelet binding protein GspB › a+b domain in platelet binding protein GspB › Rib 0.69 43.0 3.83e-01 80.9% 43.9%
2780879 1172.1.1.1 beta barrels › UL131A-like › UL130 C-terminal domain › UL130 C-terminal domain › Gp_UL130 0.68 46.0 3.92e-01 70.6% 49.5%
4009799 274.1.1.4 a+b two layers › Pili subunits › Pili subunits › Pili subunits › T2SSI 0.68 48.0 4.12e-01 75.0% 47.6%
3612373 109.4.1.438 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CHAT 0.67 56.0 3.94e-01 94.1% 50.0%
5064859 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.67 45.0 3.10e-01 92.6% 20.0%
4345365 3414.1.1.3 beta sandwiches › A putative surface protein › A putative surface protein › A putative surface protein › Bact_surface_Ig-like 0.64 40.0 3.80e-01 79.4% 52.5%
3342794 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.64 42.0 3.82e-01 76.5% 50.0%
3865506 4210.1.1.3 a+b two layers › WGR domain › WGR domain › WGR domain › PF26166 0.62 49.0 4.21e-01 97.1% 52.7%
4083856 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.62 53.0 3.27e-01 97.1% 37.0%
4945458 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 51.0 4.53e-01 95.6% 63.3%
5046747 223.1.1.13 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 0.62 51.0 3.22e-01 95.6% 17.3%
3288021 2008.6.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains 0.62 48.0 3.64e-01 88.2% 64.4%
4030677 1116.1.1.0 a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain 0.60 52.0 4.06e-01 98.5% 66.0%
3970330 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.59 52.0 4.15e-01 97.1% 49.6%
3698019 11.8.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Osmotin-like › Osmotin-like 0.59 51.0 4.09e-01 100.0% 53.8%
3273247 881.1.1.0 a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.59 49.0 3.81e-01 100.0% 42.0%
4998370 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 46.0 3.10e-01 86.8% 23.7%
4980169 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.58 47.0 3.11e-01 95.6% 42.1%
3272624 4210.1.1.1 a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.58 48.0 3.89e-01 91.2% 66.2%
3445705 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.57 39.0 3.95e-01 95.6% 70.0%
4996629 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.57 48.0 3.97e-01 95.6% 73.8%
4497101 4312.2.1.0 a+b two layers › RelE-like › YaeB-like › YaeB-like 0.57 48.0 4.49e-01 97.1% 77.5%
3356898 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.57 43.0 3.35e-01 82.4% 44.0%
3567279 243.3.1.4 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Latexin_N 0.56 44.0 3.76e-01 88.2% 82.6%
3228525 241.15.1.0 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.55 46.0 3.94e-01 92.6% 57.3%
3363098 295.1.1.5 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › Whirly 0.55 46.0 4.00e-01 94.1% 60.0%
2719766 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.55 44.0 3.58e-01 100.0% 44.7%
4988603 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.55 45.0 3.03e-01 95.6% 48.2%
None 0.55 44.0 3.40e-01 89.7% 41.0%
2772183 1116.1.1.1 a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin_dom 0.55 47.0 3.32e-01 98.5% 87.1%
3786132 330.1.1.4 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Rad52_Rad22 0.55 47.0 3.75e-01 100.0% 55.2%
4952366 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.54 44.0 2.93e-01 95.6% 49.4%
4003150 1116.1.1.1 a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin_dom 0.54 46.0 3.55e-01 97.1% 91.5%
4025486 11.8.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Osmotin-like › Osmotin-like 0.54 47.0 3.77e-01 100.0% 63.6%
3982478 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.53 45.0 3.72e-01 100.0% 64.4%
3033596 5.1.4.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,CAF1C_H4-bd 0.53 35.0 3.43e-01 80.9% 60.3%
4319690 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.53 44.0 3.76e-01 98.5% 63.3%
4231124 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 42.0 2.83e-01 100.0% 45.4%
4023930 330.1.1.2 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Ribosomal_S5 0.51 39.0 3.80e-01 97.1% 73.8%
5034706 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.51 40.0 3.96e-01 100.0% 82.7%
3957248 222.1.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.51 42.0 3.47e-01 92.6% 100.0%
4886524 3274.1.1.1 extended segments › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › Ribosomal_S5 0.51 39.0 4.02e-01 97.1% 90.8%
4067255 809.1.1.1 a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP › SmpA_OmlA 0.50 40.0 3.79e-01 89.7% 89.4%
4347716 3274.1.1.1 extended segments › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › Ribosomal_S5 0.50 39.0 3.54e-01 97.1% 62.1%
D2 high residues 89-230
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2akjA03 3.30.413.10 Alpha Beta › 2-Layer Sandwich › Sulfite Reductase Hemoprotein; domain 1 › Sulfite Reductase Hemoprotein, domain 1 0.63 46.0 4.85e-01 93.0% 84.8%
4i8oA02 3.30.160.690 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain 0.59 30.0 3.77e-01 83.1% 77.8%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.58 35.0 4.24e-01 94.4% 96.5%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.57 33.0 4.12e-01 88.7% 100.0%
1uzxA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.56 45.0 4.53e-01 93.0% 85.7%
4r03A00 2.40.128.720 Mainly Beta › Beta Barrel › Lipocalin › 0.53 35.0 3.94e-01 80.3% 85.3%
1j5yA02 3.30.1340.20 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 3H domain 0.51 27.0 3.07e-01 95.8% 63.6%
2yq2A02 2.60.40.3000 Mainly Beta › Sandwich › Immunoglobulin-like › Pestivirus envelope glycoprotein E2, domain B 0.51 24.0 3.08e-01 94.4% 77.6%
4gnxB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.50 31.0 3.33e-01 81.7% 70.5%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4436313 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.69 44.0 5.35e-01 89.4% 100.0%
3710326 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.61 37.0 4.59e-01 88.7% 98.8%
3208973 4099.1.1.4 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-O 0.59 38.0 4.25e-01 81.7% 82.5%
222972 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.57 33.0 3.93e-01 89.4% 87.6%
3607856 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.57 44.0 4.66e-01 90.8% 91.2%
4076949 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.52 27.0 3.53e-01 83.8% 97.1%
4333589 12.5.1.0 beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related 0.50 35.0 3.83e-01 85.9% 85.8%
D3 high residues 388-494
PDB
D4 high residues 528-585
PDB
D5 medium residues 236-274
PDB
Domain cluster: representative
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2r31A01 3.30.2180.10 Alpha Beta › 2-Layer Sandwich › ATP12-like › ATP12-like 0.81 75.0 6.11e-01 100.0% 59.1%
3io5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 59.0 3.62e-01 100.0% 15.1%
1e2tA03 2.40.128.150 Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases 0.70 48.0 3.41e-01 76.9% 23.1%
7ejoB01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.66 46.0 3.69e-01 79.5% 36.1%
1p5tA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.64 52.0 3.96e-01 97.4% 55.7%
1jofA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 51.0 3.00e-01 97.4% 24.7%
7pupA01 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.63 47.0 3.05e-01 89.7% 47.0%
2ltjA00 2.20.230.10 Mainly Beta › Single Sheet › Resuscitation-promoting factor rpfb fold › Resuscitation-promoting factor rpfb. 0.61 44.0 3.26e-01 79.5% 53.2%
3kvpA00 6.20.140.10 Special › Other non-globular › Immunoglobulin-like › 0.60 41.0 4.09e-01 76.9% 67.4%
3a32A02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.60 46.0 3.35e-01 100.0% 73.0%
1jhnA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.59 43.0 2.79e-01 84.6% 69.4%
4nehA01 2.130.10.130 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal 0.59 46.0 2.73e-01 100.0% 25.9%
1ri6A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 45.0 2.69e-01 89.7% 11.7%
1vhxB00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.58 43.0 3.23e-01 100.0% 34.1%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.58 43.0 3.01e-01 100.0% 80.3%
2n3gA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.58 48.0 4.03e-01 100.0% 56.9%
6aqgD02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.57 43.0 2.57e-01 84.6% 17.3%
3bt7A02 2.40.50.1070 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.57 46.0 3.29e-01 100.0% 40.7%
3zl8A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.57 46.0 2.93e-01 100.0% 18.1%
1edzA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 41.0 2.97e-01 92.3% 26.9%
2ltrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.56 41.0 3.21e-01 100.0% 33.3%
2qkdA03 2.20.25.420 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain 0.56 38.0 3.66e-01 76.9% 70.6%
2kc8A00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.56 40.0 3.15e-01 84.6% 33.7%
3x1lB02 3.30.1040.70 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.55 41.0 3.62e-01 82.1% 88.9%
4bs9A04 3.30.40.250 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.55 43.0 3.41e-01 94.9% 85.6%
4bf3A00 2.30.31.50 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Borrelia outer surface protein E/F 0.55 44.0 3.13e-01 94.9% 29.3%
2kheA00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.54 39.0 3.25e-01 87.2% 38.2%
1imuA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.54 45.0 3.37e-01 100.0% 36.4%
4obmA00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.54 40.0 2.60e-01 100.0% 26.4%
7d27A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.54 41.0 2.70e-01 100.0% 17.0%
4tm3A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 38.0 2.22e-01 100.0% 7.5%
2y8yA02 3.30.70.1210 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 0.54 36.0 2.71e-01 71.8% 77.4%
3o46A00 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.53 39.0 3.39e-01 100.0% 65.5%
5teaB00 3.90.80.10 Alpha Beta › Alpha-Beta Complex › Inorganic Pyrophosphatase › Inorganic pyrophosphatase 0.53 42.0 2.88e-01 94.9% 69.0%
1tocR02 4.10.410.10 Few Secondary Structures › Irregular › Factor Xa Inhibitor › Pancreatic trypsin inhibitor Kunitz domain 0.53 41.0 3.70e-01 89.7% 77.6%
3lp9A00 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.53 40.0 2.64e-01 94.9% 31.7%
2itmB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 38.0 2.55e-01 100.0% 51.7%
2wdqA04 4.10.80.40 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › succinate dehydrogenase protein domain 0.52 36.0 3.57e-01 74.4% 90.2%
3venA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 38.0 2.59e-01 100.0% 70.2%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 42.0 3.56e-01 100.0% 60.8%
2ci9B00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 37.0 3.07e-01 100.0% 49.0%
1v43A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 36.0 3.31e-01 100.0% 53.1%
2qrdE01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.50 38.0 2.67e-01 100.0% 58.3%
5xrwA00 2.30.330.10 Mainly Beta › Roll › Surface presentation of antigens (SPOA) › SpoA-like 0.50 40.0 3.32e-01 94.9% 73.4%
2uv8A05 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.50 36.0 2.07e-01 94.9% 69.2%
2r41A00 3.10.450.150 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › enterococcus faecalis protein 0.50 39.0 3.10e-01 100.0% 47.6%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1308290 502.1.1.2 a+b two layers › Anti-LPS factor/recA domain › Anti-LPS factor/recA domain › Anti-LPS factor/recA domain › T4_UVSX_C 0.71 60.0 4.78e-01 100.0% 48.8%
3492201 295.1.1.1 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PC4 0.71 50.0 4.10e-01 76.9% 61.3%
4324894 4018.1.1.1 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › FBPase 0.70 50.0 3.20e-01 84.6% 15.4%
4975312 2484.2.1.0 mixed a+b and a/b › Ribonuclease H-like › Methylated DNA-protein cysteine methyltransferase domain › Methylated DNA-protein cysteine methyltransferase domain 0.69 57.0 4.45e-01 100.0% 41.1%
3473908 220.1.1.157 beta barrels › PH domain-like › PH domain-like › PH domain-like › PF29715 0.66 54.0 3.66e-01 100.0% 23.6%
3199763 220.1.1.202 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_FT_N 0.66 55.0 3.96e-01 100.0% 36.8%
4017732 220.1.1.202 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_FT_N 0.65 54.0 3.71e-01 100.0% 30.7%
4093245 2003.1.5.53 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.64 54.0 3.17e-01 100.0% 16.6%
3979711 252.2.1.6 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_2 0.62 46.0 4.21e-01 100.0% 58.5%
3632692 4.8.1.0 beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.61 54.0 4.56e-01 100.0% 78.5%
3415921 394.1.1.1 few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14 0.61 44.0 4.24e-01 84.6% 92.0%
3641506 3957.1.1.0 a+b two layers › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 0.59 46.0 3.81e-01 100.0% 61.2%
4154901 2003.1.5.156 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31 0.57 47.0 2.78e-01 100.0% 16.5%
2426538 375.1.1.26 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.57 39.0 2.89e-01 74.4% 23.1%
3939425 2492.1.1.8 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › UPF0172 0.57 42.0 2.72e-01 76.9% 22.6%
None 0.57 44.0 2.67e-01 100.0% 16.2%
4027836 220.1.1.13 beta barrels › PH domain-like › PH domain-like › PH domain-like › DCP1 0.56 39.0 2.80e-01 82.1% 32.7%
134040 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.56 40.0 3.15e-01 84.6% 33.7%
3592221 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.55 42.0 3.08e-01 87.2% 49.2%
3227528 145.1.1.0 alpha arrays › F-box domain › F-box domain › F-box domain 0.55 37.0 3.83e-01 87.2% 82.9%
3286982 330.6.1.0 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 0.55 46.0 3.44e-01 100.0% 37.5%
3700169 2498.1.1.14 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M8 0.54 37.0 2.20e-01 82.1% 11.2%
5051613 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 41.0 3.15e-01 100.0% 32.2%
3937984 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 40.0 3.27e-01 100.0% 48.0%
3254115 5.1.4.56 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › NUP214 0.53 40.0 2.38e-01 100.0% 20.4%
3276498 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.53 38.0 2.30e-01 92.3% 14.4%
5030263 394.1.1.0 few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins 0.53 38.0 3.70e-01 82.1% 88.9%
3636596 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.52 40.0 3.89e-01 100.0% 86.0%
5028435 4040.1.1.1 alpha bundles › Fic-like › Fic-like › Fic-like › Fic 0.51 40.0 2.56e-01 100.0% 56.2%
4029085 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.51 39.0 2.81e-01 89.7% 47.9%
3727988 206.1.1.17 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Kdo 0.51 37.0 2.63e-01 100.0% 33.7%
5025863 2005.1.1.10 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ETF 0.51 36.0 2.55e-01 100.0% 18.9%
4938919 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.51 35.0 3.20e-01 82.1% 83.1%
4126006 325.1.7.14 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RPOC_hybrid 0.50 39.0 3.51e-01 97.4% 72.3%