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IMGVR_UViG_3300025771_000138-3300025771-Ga0208427_100017113
Arc-VirIMGVR_UViG_3300025771_000138-3300025771-Ga0208427_100017113
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 80-162
Domain cluster:
representative
CATH (68)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.91 | 52.0 | 6.84e-01 | 77.1% | 100.0% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 61.0 | 6.84e-01 | 73.5% | 100.0% |
| 4kzsA02 | 6.10.140.1870 | Special › Helix non-globular › Helix Hairpins › | 0.85 | 58.0 | 6.30e-01 | 75.9% | 82.9% |
| 4gczA03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.85 | 59.0 | 6.64e-01 | 78.3% | 92.3% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.84 | 66.0 | 6.09e-01 | 81.9% | 99.0% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.84 | 69.0 | 6.59e-01 | 86.7% | 78.9% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 65.0 | 6.99e-01 | 83.1% | 97.3% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 63.0 | 6.82e-01 | 83.1% | 95.8% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.81 | 63.0 | 6.80e-01 | 81.9% | 97.2% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.81 | 53.0 | 6.00e-01 | 75.9% | 90.3% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 59.0 | 5.60e-01 | 77.1% | 86.7% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 63.0 | 5.21e-01 | 83.1% | 54.2% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 63.0 | 6.51e-01 | 83.1% | 88.3% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 63.0 | 4.45e-01 | 83.1% | 31.6% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.80 | 65.0 | 4.85e-01 | 86.7% | 82.6% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.80 | 60.0 | 6.36e-01 | 79.5% | 88.0% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.79 | 63.0 | 6.05e-01 | 84.3% | 85.1% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.79 | 69.0 | 6.11e-01 | 92.8% | 97.4% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.79 | 71.0 | 4.93e-01 | 96.4% | 74.3% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.79 | 62.0 | 4.75e-01 | 83.1% | 39.4% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 59.0 | 5.51e-01 | 79.5% | 86.3% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 50.0 | 5.96e-01 | 74.7% | 100.0% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.78 | 63.0 | 5.33e-01 | 85.5% | 70.0% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.78 | 58.0 | 6.38e-01 | 80.7% | 98.5% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.77 | 59.0 | 4.88e-01 | 84.3% | 47.5% |
| 4nsmA00 | 6.10.250.2770 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.77 | 59.0 | 6.38e-01 | 83.1% | 94.4% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 62.0 | 5.24e-01 | 84.3% | 72.7% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.77 | 65.0 | 5.79e-01 | 90.4% | 84.1% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 48.0 | 5.08e-01 | 81.9% | 70.7% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.77 | 62.0 | 5.35e-01 | 85.5% | 61.6% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 61.0 | 6.64e-01 | 92.8% | 100.0% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.76 | 63.0 | 5.57e-01 | 96.4% | 62.2% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 56.0 | 6.13e-01 | 80.7% | 97.0% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 53.0 | 5.89e-01 | 85.5% | 98.4% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.75 | 67.0 | 6.12e-01 | 96.4% | 91.5% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 58.0 | 4.83e-01 | 81.9% | 49.6% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.74 | 58.0 | 5.09e-01 | 83.1% | 59.2% |
| 2xgjA04 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.74 | 62.0 | 5.25e-01 | 89.2% | 61.4% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.74 | 65.0 | 6.05e-01 | 95.2% | 94.1% |
| 6xm1A02 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.73 | 54.0 | 4.84e-01 | 80.7% | 56.6% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 3.92e-01 | 80.7% | 27.7% |
| 4bx8A03 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.72 | 53.0 | 4.85e-01 | 77.1% | 100.0% |
| 3ibpA01 | 1.20.58.850 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 55.0 | 5.94e-01 | 80.7% | 93.1% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 61.0 | 4.43e-01 | 91.6% | 49.1% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 57.0 | 5.33e-01 | 86.7% | 77.1% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 60.0 | 5.20e-01 | 96.4% | 59.2% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.71 | 53.0 | 5.76e-01 | 80.7% | 95.6% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 59.0 | 5.71e-01 | 94.0% | 82.4% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 56.0 | 4.40e-01 | 86.7% | 63.0% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.70 | 53.0 | 5.25e-01 | 80.7% | 77.3% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.69 | 47.0 | 4.78e-01 | 75.9% | 70.2% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 53.0 | 5.59e-01 | 83.1% | 98.6% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.69 | 41.0 | 4.87e-01 | 74.7% | 96.1% |
| 4q4hB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.69 | 55.0 | 3.67e-01 | 88.0% | 86.2% |
| 6bl6B01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.69 | 54.0 | 3.68e-01 | 86.7% | 90.8% |
| 2c2aA01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.68 | 52.0 | 5.11e-01 | 84.3% | 76.7% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.67 | 55.0 | 4.95e-01 | 100.0% | 64.7% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 51.0 | 4.53e-01 | 85.5% | 64.2% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 46.0 | 5.23e-01 | 74.7% | 98.4% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 50.0 | 4.19e-01 | 83.1% | 46.9% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 48.0 | 4.93e-01 | 79.5% | 89.7% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 50.0 | 4.72e-01 | 83.1% | 73.0% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 49.0 | 5.08e-01 | 84.3% | 88.3% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.64 | 58.0 | 4.58e-01 | 100.0% | 50.9% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.63 | 48.0 | 4.10e-01 | 86.7% | 50.4% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.60 | 54.0 | 3.64e-01 | 100.0% | 71.0% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 47.0 | 4.62e-01 | 98.8% | 78.0% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.58 | 53.0 | 4.04e-01 | 100.0% | 58.9% |
ECOD (77)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3483188 | 605.2.1.7 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › BBS2_hp | 0.91 | 68.0 | 6.73e-01 | 77.1% | 100.0% |
| 3484742 | 3922.1.1.197 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp | 0.90 | 67.0 | 6.72e-01 | 77.1% | 100.0% |
| 5039785 | 632.22.1.200 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 | 0.90 | 66.0 | 6.28e-01 | 75.9% | 67.0% |
| 4338795 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.89 | 67.0 | 5.13e-01 | 78.3% | 50.6% |
| 5059556 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.89 | 66.0 | 5.01e-01 | 77.1% | 100.0% |
| 3628737 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.88 | 70.0 | 4.88e-01 | 83.1% | 32.8% |
| 3200160 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.86 | 69.0 | 6.15e-01 | 83.1% | 92.7% |
| 4951835 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 65.0 | 5.58e-01 | 79.5% | 80.8% |
| 3595002 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.86 | 66.0 | 6.11e-01 | 79.5% | 73.0% |
| 5025381 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.85 | 68.0 | 4.38e-01 | 83.1% | 36.1% |
| 3853063 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.85 | 66.0 | 5.76e-01 | 81.9% | 57.5% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 67.0 | 5.14e-01 | 81.9% | 41.8% |
| 4488200 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.84 | 66.0 | 5.96e-01 | 81.9% | 62.4% |
| 3781506 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.84 | 66.0 | 5.25e-01 | 81.9% | 85.8% |
| 4944989 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.84 | 78.0 | 5.99e-01 | 100.0% | 97.7% |
| 3949790 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.84 | 63.0 | 5.88e-01 | 78.3% | 91.0% |
| 3473220 | 5086.1.1.209 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LIN9_C | 0.84 | 69.0 | 6.04e-01 | 85.5% | 80.0% |
| 3232850 | 3684.1.1.48 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BBS2_hp | 0.84 | 65.0 | 6.24e-01 | 81.9% | 80.0% |
| 3486385 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.84 | 69.0 | 6.32e-01 | 86.7% | 84.8% |
| 5047072 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 66.0 | 5.18e-01 | 83.1% | 48.1% |
| 3268736 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.83 | 70.0 | 4.17e-01 | 88.0% | 40.0% |
| 4998774 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.83 | 65.0 | 3.94e-01 | 81.9% | 14.6% |
| 3564741 | 3860.1.1.322 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › KELK | 0.83 | 65.0 | 4.12e-01 | 81.9% | 19.2% |
| 5067713 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.82 | 75.0 | 6.71e-01 | 96.4% | 89.1% |
| 3271624 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.82 | 66.0 | 4.03e-01 | 83.1% | 16.1% |
| 315449 | 192.8.1.2 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap | 0.82 | 64.0 | 6.75e-01 | 81.9% | 90.8% |
| 3741745 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.82 | 68.0 | 5.71e-01 | 86.7% | 64.6% |
| 4542972 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.82 | 64.0 | 4.66e-01 | 81.9% | 40.5% |
| 3878000 | 192.29.1.1 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom | 0.82 | 66.0 | 6.27e-01 | 94.0% | 73.7% |
| 4784166 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.82 | 65.0 | 7.00e-01 | 84.3% | 98.6% |
| 3882466 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.81 | 74.0 | 6.55e-01 | 97.6% | 81.7% |
| 3757869 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.81 | 70.0 | 6.64e-01 | 92.8% | 80.0% |
| 3503444 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.81 | 63.0 | 6.19e-01 | 83.1% | 77.8% |
| 4947573 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.80 | 64.0 | 4.20e-01 | 83.1% | 25.2% |
| 3589720 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 61.0 | 4.98e-01 | 80.7% | 45.5% |
| 3239791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.80 | 63.0 | 4.80e-01 | 83.1% | 39.4% |
| 3855328 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.80 | 69.0 | 6.59e-01 | 92.8% | 80.0% |
| 3258925 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.79 | 62.0 | 6.66e-01 | 83.1% | 97.1% |
| 4957994 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 63.0 | 4.11e-01 | 83.1% | 37.5% |
| 5002089 | 2004.1.1.144 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 | 0.79 | 64.0 | 4.22e-01 | 85.5% | 32.4% |
| 3849547 | 4992.1.1.25 ↗ | extended segments › RelB-like › RelB-like › RelB-like › SHCBP_N | 0.79 | 67.0 | 6.41e-01 | 92.8% | 78.9% |
| 3766572 | 4177.1.1.112 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › bMERB_dom | 0.79 | 70.0 | 5.40e-01 | 94.0% | 78.7% |
| 3215082 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.79 | 61.0 | 5.14e-01 | 81.9% | 52.6% |
| 3448091 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.79 | 64.0 | 5.74e-01 | 86.7% | 78.1% |
| 5054469 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.79 | 70.0 | 6.38e-01 | 94.0% | 89.5% |
| 3797265 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.79 | 64.0 | 5.57e-01 | 91.6% | 58.4% |
| 3186867 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 62.0 | 4.82e-01 | 83.1% | 42.4% |
| 3277724 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.78 | 62.0 | 5.89e-01 | 83.1% | 73.7% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.78 | 69.0 | 5.73e-01 | 96.4% | 59.3% |
| 3529043 | 3922.1.1.179 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › bMERB_dom | 0.78 | 69.0 | 5.27e-01 | 95.2% | 75.0% |
| 4784164 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.78 | 60.0 | 6.48e-01 | 83.1% | 97.1% |
| 3239816 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.77 | 60.0 | 4.44e-01 | 81.9% | 37.0% |
| 4956384 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.77 | 61.0 | 4.54e-01 | 83.1% | 35.9% |
| 3491418 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.77 | 60.0 | 6.27e-01 | 83.1% | 92.0% |
| 4809272 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.77 | 60.0 | 5.26e-01 | 83.1% | 63.6% |
| 4029165 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.76 | 63.0 | 3.95e-01 | 88.0% | 28.3% |
| 3487862 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.76 | 59.0 | 4.22e-01 | 83.1% | 28.7% |
| 3269107 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.76 | 68.0 | 5.00e-01 | 96.4% | 63.4% |
| 3669701 | 603.1.1.160 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 14-3-3 | 0.76 | 62.0 | 5.49e-01 | 86.7% | 72.2% |
| 3902100 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.75 | 59.0 | 5.85e-01 | 83.1% | 82.4% |
| 5041130 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.75 | 67.0 | 5.88e-01 | 100.0% | 74.4% |
| 4683070 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 60.0 | 5.02e-01 | 85.5% | 75.7% |
| 3916497 | 632.8.1.17 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Rab_eff_C | 0.75 | 65.0 | 5.70e-01 | 96.4% | 93.6% |
| 3170937 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.75 | 58.0 | 4.00e-01 | 83.1% | 25.1% |
| 2323907 | 212.1.1.24 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 | 0.75 | 58.0 | 4.20e-01 | 83.1% | 30.8% |
| 4951266 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.74 | 62.0 | 3.92e-01 | 90.4% | 44.0% |
| 3521820 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.72 | 55.0 | 3.99e-01 | 83.1% | 29.8% |
| 3268786 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.71 | 59.0 | 5.13e-01 | 90.4% | 82.4% |
| 4266510 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.71 | 65.0 | 5.90e-01 | 96.4% | 97.1% |
| 3536875 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.71 | 55.0 | 3.84e-01 | 85.5% | 68.1% |
| 3883526 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.71 | 62.0 | 4.18e-01 | 96.4% | 73.0% |
| 4935668 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.70 | 62.0 | 5.31e-01 | 96.4% | 67.7% |
| 3936091 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.70 | 60.0 | 4.27e-01 | 95.2% | 73.9% |
| 3824276 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.68 | 51.0 | 4.04e-01 | 81.9% | 38.9% |
| 3929349 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.68 | 55.0 | 4.19e-01 | 90.4% | 95.6% |
| 3258488 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 58.0 | 5.44e-01 | 96.4% | 88.0% |
| 4479516 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.61 | 49.0 | 4.71e-01 | 94.0% | 97.0% |
D2
medium
residues 182-244
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2z2xA00 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.58 | 51.0 | 3.24e-01 | 100.0% | 75.8% |