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IMGVR_UViG_3300025818_001172-3300025818-Ga0208542_100267814

Arc-Vir

IMGVR_UViG_3300025818_001172-3300025818-Ga0208542_100267814

Quality

93.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-26_81-154
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gxzD00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.64 38.0 3.18e-01 78.0% 33.5%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.62 46.0 5.01e-01 78.0% 97.5%
3otiA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.61 49.0 3.86e-01 89.0% 68.8%
4z7xB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.59 45.0 3.58e-01 81.0% 52.4%
4a0zA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 30.0 3.74e-01 73.0% 81.4%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 42.0 4.15e-01 78.0% 100.0%
2r0bA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 48.0 4.27e-01 94.0% 98.0%
2g6zA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.55 46.0 4.12e-01 94.0% 97.3%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.54 42.0 3.36e-01 84.0% 93.8%
6k41R00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 39.0 3.00e-01 75.0% 97.9%
1j09A05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.54 34.0 3.43e-01 90.0% 63.3%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 32.0 3.48e-01 71.0% 70.6%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.53 39.0 3.45e-01 77.0% 56.8%
1txgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.53 39.0 3.48e-01 81.0% 80.0%
2id6A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 36.0 3.15e-01 70.0% 93.5%
3tl4X01 1.10.8.1290 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1 0.53 41.0 3.98e-01 96.0% 74.6%
3pxpA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.51 38.0 3.90e-01 79.0% 84.9%
2ofyA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.51 34.0 3.97e-01 73.0% 100.0%
3gi8C00 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.50 44.0 2.93e-01 99.0% 87.6%
7og5F01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.50 35.0 3.13e-01 97.0% 47.7%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5053357 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.67 58.0 5.10e-01 95.0% 66.7%
4943989 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.67 59.0 5.11e-01 99.0% 65.0%
4030519 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.67 58.0 5.31e-01 97.0% 100.0%
3431012 101.1.10.7 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.67 57.0 5.76e-01 94.0% 100.0%
5073287 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.67 59.0 4.96e-01 100.0% 61.7%
4999090 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.66 57.0 5.25e-01 95.0% 76.9%
5048633 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.65 58.0 4.98e-01 99.0% 66.3%
3528299 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 47.0 4.57e-01 87.0% 80.0%
3675163 3881.1.1.1 alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.58 44.0 3.53e-01 79.0% 99.5%
4098703 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.55 43.0 3.19e-01 85.0% 57.2%
3606961 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.54 42.0 3.81e-01 86.0% 79.3%
3514956 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.54 43.0 3.56e-01 90.0% 65.6%
5010685 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 42.0 3.72e-01 86.0% 98.0%
3944606 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.53 41.0 2.98e-01 84.0% 84.2%
5006106 5051.1.1.10 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.51 44.0 3.00e-01 100.0% 91.9%
3573366 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.50 38.0 3.13e-01 96.0% 41.5%
D2 medium residues 27-80
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jiuA00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.75 60.0 4.86e-01 88.9% 51.4%
4jixB00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.66 55.0 4.56e-01 98.1% 54.8%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.61 47.0 3.76e-01 81.5% 53.0%
3netB01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 50.0 3.21e-01 100.0% 56.5%
3dteA01 1.10.10.2910 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 46.0 3.62e-01 100.0% 39.3%
2epkX01 3.30.160.230 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › N-acetyl-beta-d-glucosaminidase 0.59 49.0 4.32e-01 92.6% 63.7%
1vbkA02 3.30.2300.10 Alpha Beta › 2-Layer Sandwich › THUMP fold › THUMP superfamily 0.59 44.0 3.91e-01 81.5% 56.1%
4q20A02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.58 46.0 3.45e-01 90.7% 93.3%
4pl9A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.57 44.0 3.33e-01 90.7% 91.3%
4s2rP02 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.56 48.0 3.53e-01 100.0% 88.6%
3grfA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.55 43.0 3.25e-01 94.4% 96.4%
1xjcA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 47.0 3.46e-01 96.3% 79.9%
3asaA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 47.0 3.49e-01 96.3% 56.8%
7zp0A01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.54 43.0 3.33e-01 96.3% 100.0%
4q0cA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.54 44.0 3.26e-01 96.3% 49.7%
2kl3A01 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.53 36.0 3.03e-01 72.2% 75.5%
5ybwA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 41.0 3.62e-01 98.1% 100.0%
3d36B01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.52 40.0 3.05e-01 92.6% 88.7%
1ihnA00 3.40.1230.10 Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical Protein Mth938; Chain: A, › MTH938-like 0.52 41.0 3.34e-01 92.6% 69.9%
2orwB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.35e-01 96.3% 90.6%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 40.0 2.83e-01 94.4% 69.0%
2o0aA00 3.40.850.20 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › 0.51 41.0 2.76e-01 100.0% 80.3%
1vk1A01 3.90.1530.10 Alpha Beta › Alpha-Beta Complex › Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain › Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain 0.51 35.0 2.87e-01 72.2% 51.0%
3m9gA02 3.30.10.20 Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › 0.51 40.0 3.80e-01 92.6% 85.3%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4969796 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.71 55.0 4.54e-01 87.0% 55.0%
4024134 2498.1.1.65 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › MATCAP 0.71 60.0 3.68e-01 100.0% 16.7%
5027859 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.70 58.0 4.40e-01 96.3% 55.1%
5061805 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.69 57.0 4.66e-01 98.1% 57.3%
3754954 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.69 59.0 3.92e-01 100.0% 24.3%
3868678 2498.1.1.65 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › MATCAP 0.69 59.0 3.63e-01 100.0% 17.0%
5077870 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.69 57.0 3.83e-01 96.3% 27.3%
4930641 2498.1.1.58 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF2201_N 0.68 56.0 4.04e-01 98.1% 33.5%
3290645 2498.1.1.29 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 0.67 54.0 4.21e-01 88.9% 42.5%
4934179 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.67 57.0 3.75e-01 100.0% 25.7%
3376255 2498.1.1.112 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1, TAF2_3rd 0.67 55.0 3.36e-01 96.3% 18.2%
3986352 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.66 55.0 3.46e-01 96.3% 38.3%
3928509 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.65 53.0 3.40e-01 96.3% 22.7%
3990083 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 42.0 4.05e-01 94.4% 64.6%
3954373 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 46.0 2.96e-01 88.9% 16.9%
4974758 2008.1.1.51 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC 0.59 51.0 3.71e-01 100.0% 84.5%
2132559 102.1.1.28 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 0.57 43.0 3.33e-01 98.1% 35.2%
3753120 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.56 40.0 2.57e-01 74.1% 28.5%
5020654 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 42.0 2.89e-01 81.5% 51.7%
4948463 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 46.0 3.17e-01 96.3% 87.6%
5067350 7518.1.1.0 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like 0.54 42.0 3.49e-01 88.9% 91.4%
4998095 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.54 45.0 3.13e-01 94.4% 87.9%
3203855 109.4.1.18 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA 0.54 42.0 2.56e-01 85.2% 22.9%
3988981 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.54 43.0 3.17e-01 98.1% 62.2%
3947118 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.54 42.0 3.20e-01 96.3% 93.1%
4997998 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 44.0 3.08e-01 94.4% 91.1%
4998552 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 38.0 2.56e-01 74.1% 58.1%
5014967 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 45.0 3.16e-01 96.3% 77.1%
4990363 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.53 44.0 3.07e-01 94.4% 45.8%
3963903 102.1.1.28 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 0.53 39.0 2.85e-01 98.1% 25.6%
4996695 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 44.0 3.12e-01 96.3% 91.4%
4947053 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 39.0 2.70e-01 81.5% 54.1%
4948399 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 39.0 2.68e-01 81.5% 52.6%
3589922 102.1.1.28 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 0.52 39.0 2.89e-01 98.1% 27.6%
3301688 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 41.0 2.40e-01 87.0% 16.6%
4987840 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.51 42.0 2.92e-01 96.3% 79.0%
4941583 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.51 43.0 3.03e-01 96.3% 92.2%
4959341 2008.1.1.152 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF2130 0.51 41.0 3.27e-01 94.4% 80.0%
3390790 2498.5.1.0 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like 0.51 43.0 3.73e-01 100.0% 98.9%
3600960 7516.1.1.0 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.51 41.0 2.38e-01 88.9% 25.4%
3959918 102.1.1.28 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 0.50 42.0 2.85e-01 98.1% 71.3%
5059098 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 41.0 2.79e-01 98.1% 44.3%