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IMGVR_UViG_3300025877_000037-3300025877-Ga0208460_100010823
Arc-VirIMGVR_UViG_3300025877_000037-3300025877-Ga0208460_100010823
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-43_143-203
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 46.0 | 3.63e-01 | 73.5% | 78.0% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.63 | 40.0 | 3.75e-01 | 72.5% | 51.6% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.62 | 44.0 | 3.98e-01 | 73.5% | 80.0% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 42.0 | 3.71e-01 | 70.6% | 61.3% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.61 | 39.0 | 3.66e-01 | 73.5% | 51.2% |
| 3f5cB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.61 | 55.0 | 4.52e-01 | 100.0% | 66.1% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.59 | 41.0 | 2.88e-01 | 71.6% | 67.4% |
| 2etsA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.58 | 43.0 | 4.20e-01 | 80.4% | 69.6% |
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 43.0 | 4.26e-01 | 84.3% | 79.0% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 41.0 | 3.74e-01 | 78.4% | 86.1% |
| 5an3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 39.0 | 3.59e-01 | 100.0% | 56.6% |
| 2w53B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 41.0 | 3.50e-01 | 79.4% | 81.5% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 42.0 | 3.75e-01 | 84.3% | 92.8% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.54 | 49.0 | 4.43e-01 | 99.0% | 77.9% |
| 3q1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.54 | 46.0 | 4.19e-01 | 95.1% | 89.2% |
| 1e5rB02 | 1.10.1720.10 | Mainly Alpha › Orthogonal Bundle › Proline Oxidase; Chain: A, Domain 2 › L-proline 3-hydroxylase, C-terminal domain | 0.52 | 36.0 | 3.93e-01 | 93.1% | 85.7% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.52 | 43.0 | 4.06e-01 | 90.2% | 89.3% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 44.0 | 3.84e-01 | 95.1% | 88.4% |
| 4fjvA02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.51 | 38.0 | 3.40e-01 | 78.4% | 72.2% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.51 | 44.0 | 3.87e-01 | 97.1% | 83.1% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 43.0 | 3.76e-01 | 94.1% | 73.4% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 44.0 | 3.73e-01 | 98.0% | 81.1% |
| 4j5tA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.50 | 46.0 | 2.96e-01 | 100.0% | 46.9% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 43.0 | 3.76e-01 | 97.1% | 72.3% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4928042 | 4275.1.1.0 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like | 0.73 | 58.0 | 6.10e-01 | 83.3% | 100.0% |
| 4541195 | 3755.3.1.470 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB | 0.68 | 49.0 | 4.46e-01 | 73.5% | 99.2% |
| 5069603 | 601.18.1.30 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm | 0.68 | 48.0 | 4.51e-01 | 73.5% | 61.6% |
| 4823728 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.66 | 48.0 | 4.86e-01 | 76.5% | 89.4% |
| 3659411 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.64 | 44.0 | 4.34e-01 | 70.6% | 75.5% |
| 4241645 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.63 | 45.0 | 4.76e-01 | 73.5% | 85.6% |
| 5070606 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.62 | 44.0 | 4.03e-01 | 73.5% | 67.4% |
| 3767418 | 4177.1.1.9 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom | 0.62 | 44.0 | 3.25e-01 | 73.5% | 76.2% |
| 4581983 | 5086.1.1.13 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB | 0.62 | 44.0 | 3.94e-01 | 73.5% | 92.1% |
| 5018648 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.61 | 41.0 | 4.50e-01 | 73.5% | 82.4% |
| 4950309 | 3843.1.1.36 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2107 | 0.61 | 42.0 | 4.80e-01 | 83.3% | 98.7% |
| 3865873 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.60 | 43.0 | 3.74e-01 | 76.5% | 52.5% |
| 4246492 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.59 | 44.0 | 4.57e-01 | 82.4% | 84.2% |
| 3374493 | 5069.1.3.69 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ETR1_N | 0.59 | 43.0 | 4.46e-01 | 77.5% | 84.2% |
| 3518177 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.58 | 41.0 | 3.44e-01 | 72.5% | 81.7% |
| 3590809 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 39.0 | 3.03e-01 | 73.5% | 84.3% |
| 3290592 | 191.1.1.64 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › DUF4254 | 0.54 | 49.0 | 4.48e-01 | 100.0% | 76.2% |
| 4020539 | 601.1.2.72 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › SesA | 0.51 | 43.0 | 3.84e-01 | 96.1% | 98.1% |
D2
high
residues 48-139
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5i0dA05 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.71 | 55.0 | 4.77e-01 | 100.0% | 54.7% |
| 5jpnC01 | 2.60.40.690 | Mainly Beta › Sandwich › Immunoglobulin-like › Alpha-macroglobulin, receptor-binding domain | 0.60 | 46.0 | 4.11e-01 | 100.0% | 57.1% |
| 4j3vA04 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.59 | 39.0 | 4.21e-01 | 98.9% | 81.8% |
| 2qf4A01 | 2.40.10.340 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Rod shape-determining protein MreC, domain 1 | 0.56 | 40.0 | 4.22e-01 | 100.0% | 87.3% |
| 2fsuA00 | 3.40.50.11310 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Bacterial phosphonate metabolism protein PhnH | 0.52 | 41.0 | 3.42e-01 | 88.0% | 95.9% |
| 2cpdA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.51 | 35.0 | 3.74e-01 | 92.4% | 86.7% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5081050 | 4275.1.1.11 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › SU10_adaptor | 0.70 | 58.0 | 4.38e-01 | 100.0% | 40.0% |
| 5083772 | 12.6.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related | 0.63 | 56.0 | 4.90e-01 | 100.0% | 66.4% |
| 5038375 | 4081.1.1.2 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT | 0.59 | 52.0 | 4.09e-01 | 100.0% | 53.0% |
| 3217107 | 12.1.1.94 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › DUF4139 | 0.54 | 47.0 | 4.18e-01 | 100.0% | 66.4% |
| 5063547 | 310.1.1.2 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arg_tRNA_synt_N | 0.52 | 36.0 | 3.80e-01 | 82.6% | 78.8% |
| 3316738 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.52 | 38.0 | 2.61e-01 | 78.3% | 55.7% |
| 3164975 | 306.6.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D | 0.51 | 38.0 | 4.10e-01 | 95.7% | 98.7% |