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IMGVR_UViG_3300025902_000582-3300025902-Ga0209202_10013263
Arc-VirIMGVR_UViG_3300025902_000582-3300025902-Ga0209202_10013263
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-164
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.86 | 64.0 | 7.17e-01 | 87.6% | 96.8% |
| 3o10C00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.76 | 60.0 | 6.50e-01 | 86.3% | 96.3% |
| 3mfnB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.72 | 55.0 | 6.17e-01 | 85.7% | 100.0% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.67 | 41.0 | 5.00e-01 | 85.7% | 97.0% |
| 5d0yA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.62 | 34.0 | 3.48e-01 | 100.0% | 54.2% |
| 4aidA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.61 | 27.0 | 3.71e-01 | 87.6% | 79.3% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.61 | 37.0 | 4.57e-01 | 76.4% | 99.0% |
| 1yfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.61 | 50.0 | 4.17e-01 | 86.3% | 70.6% |
| 8itfR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 50.0 | 4.15e-01 | 88.8% | 85.7% |
| 1a7vA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.60 | 42.0 | 4.69e-01 | 87.0% | 92.8% |
| 5af7B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 46.0 | 4.85e-01 | 82.6% | 88.5% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 47.0 | 4.76e-01 | 82.6% | 84.8% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.59 | 42.0 | 4.64e-01 | 87.0% | 91.6% |
| 5xnyA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 46.0 | 3.95e-01 | 85.7% | 79.1% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 46.0 | 3.92e-01 | 88.8% | 85.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 40.0 | 4.37e-01 | 86.3% | 92.2% |
| 4uyeA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.56 | 35.0 | 4.08e-01 | 79.5% | 90.8% |
| 1fftC00 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.55 | 43.0 | 4.14e-01 | 86.3% | 71.4% |
| 4oo2A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 48.0 | 4.40e-01 | 91.9% | 85.9% |
| 4nleA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.55 | 50.0 | 4.27e-01 | 98.1% | 73.8% |
| 4ecgA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.55 | 44.0 | 3.40e-01 | 85.7% | 77.4% |
| 5uh5D02 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.55 | 37.0 | 3.96e-01 | 96.9% | 79.0% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.54 | 41.0 | 3.87e-01 | 79.5% | 67.9% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 42.0 | 4.28e-01 | 86.3% | 95.0% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 40.0 | 4.22e-01 | 85.7% | 90.4% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 47.0 | 3.99e-01 | 100.0% | 85.6% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.51 | 38.0 | 3.84e-01 | 97.5% | 75.3% |
| 4w66B00 | 1.20.1050.130 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 39.0 | 3.52e-01 | 79.5% | 95.9% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5054201 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.95 | 64.0 | 7.81e-01 | 85.1% | 100.0% |
| 5082140 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.89 | 62.0 | 7.22e-01 | 85.7% | 95.8% |
| 5054741 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.89 | 59.0 | 7.07e-01 | 86.3% | 97.3% |
| 4938272 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.86 | 64.0 | 7.22e-01 | 85.7% | 97.6% |
| 5030702 | 601.7.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 | 0.85 | 60.0 | 6.77e-01 | 86.3% | 92.0% |
| 5030626 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.84 | 60.0 | 6.95e-01 | 85.1% | 97.5% |
| 5029372 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.84 | 62.0 | 6.94e-01 | 86.3% | 95.3% |
| 5057869 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.83 | 59.0 | 6.86e-01 | 85.1% | 97.5% |
| 4993513 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.83 | 59.0 | 6.84e-01 | 85.1% | 97.5% |
| 4967176 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.83 | 60.0 | 6.95e-01 | 84.5% | 100.0% |
| 3962320 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.82 | 55.0 | 6.35e-01 | 87.6% | 91.7% |
| 3797496 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.82 | 49.0 | 6.04e-01 | 83.2% | 92.4% |
| 5032053 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.81 | 62.0 | 6.92e-01 | 85.1% | 97.7% |
| 4969330 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.80 | 60.0 | 6.64e-01 | 86.3% | 95.3% |
| 4934426 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.80 | 58.0 | 6.66e-01 | 85.1% | 100.0% |
| 5074964 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.80 | 56.0 | 6.52e-01 | 84.5% | 100.0% |
| 4967463 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.78 | 59.0 | 6.68e-01 | 83.9% | 100.0% |
| 5040311 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.78 | 58.0 | 6.53e-01 | 85.7% | 98.4% |
| 5013445 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.76 | 57.0 | 6.35e-01 | 85.7% | 96.2% |
| 5057946 | 3960.1.1.0 ↗ | alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain | 0.75 | 48.0 | 5.78e-01 | 85.1% | 97.1% |
| 5054790 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.75 | 61.0 | 6.29e-01 | 85.1% | 87.1% |
| 5080554 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.75 | 56.0 | 6.28e-01 | 86.3% | 99.2% |
| 5009815 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.75 | 59.0 | 6.37e-01 | 85.7% | 97.0% |
| 4934383 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.75 | 59.0 | 6.30e-01 | 85.7% | 93.6% |
| 5036206 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.74 | 59.0 | 6.42e-01 | 86.3% | 97.8% |
| 4980636 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.73 | 58.0 | 6.13e-01 | 87.0% | 92.4% |
| 3217714 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.72 | 52.0 | 5.53e-01 | 84.5% | 85.0% |
| 5000390 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.70 | 60.0 | 5.70e-01 | 100.0% | 78.4% |
| 3581398 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 48.0 | 5.20e-01 | 86.3% | 95.6% |
| 3924415 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.60 | 49.0 | 4.01e-01 | 87.6% | 80.7% |
| 3709421 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.59 | 30.0 | 4.08e-01 | 72.0% | 92.9% |
| 3223631 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.58 | 45.0 | 4.46e-01 | 80.7% | 87.6% |
| 3441821 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 40.0 | 4.11e-01 | 85.1% | 76.7% |
| 3447211 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 44.0 | 4.02e-01 | 90.1% | 65.9% |
| 4965147 | 5001.1.1.292 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM | 0.53 | 49.0 | 4.29e-01 | 99.4% | 76.6% |
| 4963694 | 5001.1.1.292 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM | 0.53 | 48.0 | 4.31e-01 | 99.4% | 78.2% |
| 5055497 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.52 | 43.0 | 4.39e-01 | 86.3% | 95.5% |
| 4986123 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.52 | 41.0 | 3.80e-01 | 100.0% | 64.3% |
| 3584946 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 38.0 | 3.38e-01 | 80.1% | 53.4% |
| 4508275 | 4946.1.1.1 ↗ | alpha bundles › helical domain in YacF-like proteins › helical domain in YacF-like proteins › helical domain in YacF-like proteins › ZapD | 0.51 | 41.0 | 4.12e-01 | 87.6% | 92.9% |