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IMGVR_UViG_3300025997_000018-3300025997-Ga0210013_100025679

Arc-Vir

IMGVR_UViG_3300025997_000018-3300025997-Ga0210013_100025679

Quality

91.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 114-225
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2c5uA02 1.10.3550.20 Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › 0.80 73.0 6.92e-01 99.1% 90.1%
1n81A00 1.10.3030.10 Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 0.71 56.0 4.71e-01 83.0% 90.3%
2okuA00 1.20.120.470 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain 0.63 40.0 3.89e-01 90.2% 57.4%
4i9oA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.63 35.0 4.07e-01 86.6% 76.9%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.61 39.0 3.89e-01 82.1% 61.3%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.60 34.0 3.74e-01 96.4% 67.4%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 41.0 3.97e-01 90.2% 61.5%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 36.0 3.71e-01 90.2% 63.6%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.58 39.0 3.80e-01 93.8% 60.5%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.56 41.0 3.70e-01 75.0% 73.4%
3x3bA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 41.0 3.14e-01 78.6% 50.2%
7d5qA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 46.0 3.88e-01 92.9% 96.2%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.53 43.0 4.02e-01 99.1% 71.0%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 44.0 3.53e-01 90.2% 90.5%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 41.0 3.83e-01 83.9% 72.5%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 41.0 4.06e-01 83.9% 81.1%
1sigA00 1.10.601.10 Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor 0.51 46.0 3.37e-01 99.1% 86.9%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 40.0 3.73e-01 83.9% 67.8%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 43.0 3.35e-01 90.2% 68.5%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 40.0 3.68e-01 82.1% 70.6%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.51 39.0 3.54e-01 88.4% 61.5%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 40.0 3.81e-01 83.9% 73.5%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 41.0 3.92e-01 87.5% 75.2%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3270967 633.6.1.2 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX 0.66 38.0 3.56e-01 92.9% 45.0%
4996547 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 36.0 3.27e-01 85.7% 43.2%
3259226 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.60 45.0 3.75e-01 78.6% 97.0%
3249529 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.58 39.0 3.72e-01 89.3% 57.0%
4990614 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.57 46.0 3.52e-01 88.4% 61.4%
5058654 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.57 39.0 3.51e-01 87.5% 51.0%
3194749 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 46.0 3.55e-01 88.4% 83.4%
3190762 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 44.0 3.49e-01 87.5% 90.7%
4058777 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 44.0 3.53e-01 87.5% 86.5%
4981180 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 44.0 3.72e-01 89.3% 91.1%
3721626 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 44.0 3.48e-01 88.4% 84.8%
3636767 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 3.54e-01 89.3% 86.5%
4930330 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 44.0 3.59e-01 88.4% 74.5%
3723610 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 43.0 3.40e-01 88.4% 88.5%
3510536 138.1.1.5 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA_pol3_gamma3 0.52 33.0 3.22e-01 82.1% 58.3%
3624173 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 43.0 3.45e-01 91.1% 85.3%
3787788 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 40.0 3.15e-01 82.1% 50.0%
4055862 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.51 37.0 3.42e-01 75.9% 99.3%
3597275 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.51 36.0 3.62e-01 73.2% 94.8%
3191032 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 41.0 3.19e-01 87.5% 79.6%
4675001 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 41.0 3.41e-01 88.4% 80.0%
4115362 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 42.0 3.43e-01 90.2% 89.0%
D2 medium residues 1-61
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1s68A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.83 72.0 5.85e-01 96.7% 61.9%
2vugA03 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.82 72.0 6.03e-01 96.7% 65.7%
1xdnA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.80 69.0 5.16e-01 98.4% 69.7%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.78 68.0 4.88e-01 100.0% 38.3%
7o85C01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 38.0 3.57e-01 95.1% 45.5%
5a2fA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 37.0 3.11e-01 95.1% 34.9%
4kt3B00 3.10.450.170 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › type vi secretion system effector-immunity co pseudomonas protegens 0.59 42.0 3.37e-01 82.0% 36.7%
7qi3A01 3.30.2140.20 Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › 0.57 42.0 2.71e-01 82.0% 78.5%
2fnoA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.55 34.0 2.92e-01 80.3% 39.4%
1dpgA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.54 42.0 2.71e-01 85.2% 77.7%
3byqA00 3.30.1330.110 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › BB2672 0.54 43.0 3.17e-01 95.1% 68.1%
1lqlA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.54 44.0 3.81e-01 96.7% 78.6%
5xgbA03 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.54 43.0 3.00e-01 96.7% 57.0%
2ihmB03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 45.0 3.75e-01 98.4% 85.1%
1nezH00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 41.0 3.27e-01 83.6% 65.0%
1ne2B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 38.0 2.81e-01 78.7% 69.9%
2mcqA01 3.30.300.90 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like 0.52 43.0 4.09e-01 96.7% 81.3%
7lfbH01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 32.0 2.68e-01 93.4% 30.8%
1kcgC00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.51 39.0 2.99e-01 88.5% 40.0%
1qsmD00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 41.0 3.11e-01 100.0% 36.2%
2qecA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 40.0 3.07e-01 100.0% 80.6%
4pswA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 40.0 3.29e-01 96.7% 84.2%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3271939 206.1.3.24 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_lig_T4_1 0.90 83.0 5.17e-01 100.0% 22.8%
4881570 206.1.3.24 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_lig_T4_1 0.86 79.0 5.07e-01 100.0% 25.7%
5003826 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.84 76.0 4.91e-01 100.0% 27.2%
5007422 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.83 75.0 4.87e-01 100.0% 27.2%
4962282 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.82 74.0 5.10e-01 100.0% 35.4%
5077223 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.82 73.0 4.41e-01 100.0% 18.5%
5012458 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.81 72.0 4.80e-01 100.0% 28.7%
5070559 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.81 72.0 4.78e-01 100.0% 28.3%
1698226 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.81 72.0 4.94e-01 100.0% 34.3%
5017089 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.81 72.0 4.78e-01 100.0% 30.0%
3270508 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.79 70.0 4.69e-01 100.0% 30.1%
3399889 3481.1.1.0 extended segments › TraN protein › TraN protein › TraN protein 0.64 48.0 4.68e-01 93.4% 72.1%
4992091 2004.1.1.42 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.61 41.0 2.48e-01 72.1% 24.1%
4030017 837.1.1.0 a+b two layers › Ribosomal protein S16 › Ribosomal protein S16 › Ribosomal protein S16 0.59 38.0 3.59e-01 72.1% 53.3%
5036923 2004.1.1.42 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.58 39.0 2.32e-01 70.5% 27.1%
3232363 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 47.0 3.34e-01 95.1% 30.2%
3401008 11.1.1.1154 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29963 0.57 46.0 4.12e-01 95.1% 76.8%
4941910 327.18.1.0 a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A 0.55 44.0 4.47e-01 96.7% 93.3%
3902971 5.1.3.9 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › OLF 0.54 44.0 2.92e-01 93.4% 82.2%
4084869 213.1.1.14 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_16 0.53 43.0 3.30e-01 100.0% 86.9%
3689335 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 37.0 3.84e-01 95.1% 83.6%
3315597 252.1.1.0 a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD 0.50 37.0 3.46e-01 82.0% 69.6%
1510680 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.50 40.0 3.07e-01 100.0% 80.1%
D3 medium residues 62-113
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xhbA01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.63 52.0 3.41e-01 98.1% 84.9%
2mkyA00 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.60 39.0 3.85e-01 73.1% 60.3%
4b09B02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 41.0 3.35e-01 71.2% 61.2%
3d6wB02 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.60 31.0 3.51e-01 76.9% 64.1%
2jiiA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.60 46.0 3.17e-01 86.5% 91.5%
3h8hA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.59 44.0 3.63e-01 78.8% 76.1%
4lrjA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.59 41.0 3.71e-01 73.1% 52.1%
1hbxA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.59 42.0 3.95e-01 88.5% 59.2%
2anvA00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.59 43.0 3.26e-01 84.6% 36.3%
3m4aA03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.59 41.0 3.30e-01 76.9% 91.5%
1itpA00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.58 39.0 3.52e-01 71.2% 48.1%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.58 39.0 3.21e-01 75.0% 35.9%
4yzrA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.57 47.0 2.87e-01 98.1% 70.4%
7c1hB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.57 47.0 3.40e-01 100.0% 51.2%
1vbkA01 3.30.70.1510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like 0.56 39.0 3.44e-01 75.0% 59.0%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 48.0 3.89e-01 98.1% 61.9%
1vq0A02 3.90.1280.10 Alpha Beta › Alpha-Beta Complex › CBS domain Like › HSP33 redox switch-like 0.56 38.0 3.78e-01 76.9% 66.7%
2v79A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 45.0 3.53e-01 92.3% 53.9%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 46.0 3.72e-01 98.1% 66.0%
1r6yA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 39.0 3.13e-01 75.0% 50.5%
1c7uA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.54 39.0 3.83e-01 88.5% 69.8%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 43.0 3.46e-01 90.4% 57.1%
1nhyA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 33.0 2.94e-01 71.2% 40.3%
2pt7G02 3.30.1370.180 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 41.0 3.91e-01 90.4% 70.1%
2wnsA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 2.74e-01 82.7% 48.7%
5b3hC01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.53 32.0 3.32e-01 84.6% 64.6%
4gs5A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.53 43.0 2.86e-01 96.2% 85.2%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.53 36.0 2.79e-01 82.7% 29.4%
4esbA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 43.0 3.56e-01 96.2% 67.0%
1nyrA03 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.53 44.0 2.81e-01 100.0% 71.8%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.52 39.0 3.27e-01 82.7% 94.8%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 41.0 3.43e-01 90.4% 58.2%
1yyvB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 41.0 3.27e-01 90.4% 47.3%
1qviA01 1.20.120.720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain 0.52 42.0 3.31e-01 92.3% 49.6%
3eo7A02 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.52 44.0 2.88e-01 98.1% 56.0%
2gaxA00 3.40.1490.10 Alpha Beta › 3-Layer(aba) Sandwich › Bit1 › Bit1 0.51 38.0 3.02e-01 88.5% 79.1%
2e1mA05 1.10.405.10 Mainly Alpha › Orthogonal Bundle › Guanine Nucleotide Dissociation Inhibitor; domain 1 › Guanine Nucleotide Dissociation Inhibitor, domain 1 0.51 35.0 3.00e-01 73.1% 97.8%
5adxJ01 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.51 37.0 3.20e-01 80.8% 59.1%
7z8iC01 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.51 35.0 3.11e-01 73.1% 49.4%
1fjeB01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.51 40.0 3.54e-01 96.2% 58.0%
3nftA00 1.20.1710.10 Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like 0.51 38.0 2.62e-01 94.2% 70.6%
2fswA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 40.0 3.29e-01 90.4% 52.9%
1bd3A00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 43.0 2.88e-01 100.0% 46.9%
3isxA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.50 42.0 2.75e-01 94.2% 97.6%
2pa8D01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.50 36.0 3.09e-01 76.9% 59.1%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3578641 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.73 40.0 3.62e-01 71.2% 40.0%
3581763 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.70 39.0 3.54e-01 71.2% 40.0%
4980062 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.64 45.0 3.66e-01 75.0% 40.0%
4979735 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.64 45.0 3.70e-01 75.0% 42.2%
5057127 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.44e-01 100.0% 41.2%
3924514 109.4.1.83 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf 0.60 52.0 3.31e-01 100.0% 21.7%
3445779 101.1.2.245 alpha arrays › HTH › HTH › winged helix domain › PORR 0.59 48.0 3.73e-01 94.2% 48.8%
4377282 310.1.1.2 a+b two layers › RRF/tRNA synthetase additional domain-like › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arg_tRNA_synt_N 0.59 39.0 3.27e-01 96.2% 38.9%
3640563 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 39.0 3.44e-01 71.2% 48.0%
3879574 209.1.1.1 a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C 0.58 41.0 3.13e-01 78.8% 48.6%
3403813 603.2.1.12 alpha bundles › STAT-like › STAT › STAT › 7tm_7 0.57 44.0 2.73e-01 90.4% 43.5%
3286186 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 41.0 3.03e-01 84.6% 27.1%
3964348 304.28.1.3 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD-TM1 0.56 39.0 3.48e-01 73.1% 54.7%
5045741 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.55 38.0 3.69e-01 76.9% 72.3%
4025389 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 46.0 3.55e-01 100.0% 97.8%
4942265 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 43.0 3.78e-01 90.4% 74.1%
4935806 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 41.0 3.39e-01 82.7% 70.0%
3627409 6166.1.1.1 alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 0.54 38.0 2.59e-01 73.1% 63.0%
3361891 246.3.1.4 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos2 0.54 42.0 2.73e-01 96.2% 43.5%
4970916 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 40.0 3.27e-01 82.7% 56.2%
4950276 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.54 44.0 2.97e-01 90.4% 31.3%
3585434 109.4.1.2720 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Peptidase_M17 0.53 44.0 2.64e-01 100.0% 37.8%
5011108 1036.1.1.1 a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.53 38.0 3.18e-01 76.9% 48.0%
3939270 207.1.1.156 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › PF27094 0.53 43.0 2.90e-01 100.0% 57.0%
3971842 876.1.1.1 a+b complex topology › ParB/Sulfiredoxin › ParB/Sulfiredoxin › ParB/Sulfiredoxin › ParBc 0.53 41.0 3.20e-01 92.3% 90.8%
3680963 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.53 44.0 4.01e-01 94.2% 71.4%
4019933 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 43.0 2.90e-01 94.2% 31.0%
10995 2501.1.1.2 a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › DUF2000 0.52 38.0 2.86e-01 78.8% 73.3%
3164240 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.52 36.0 3.36e-01 76.9% 55.7%
5004895 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.52 44.0 3.02e-01 94.2% 81.7%
3301908 101.1.2.281 alpha arrays › HTH › HTH › winged helix domain › Tfb2 0.51 40.0 3.39e-01 90.4% 60.0%
1203389 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 36.0 2.53e-01 76.9% 42.6%
3974474 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.51 36.0 2.94e-01 73.1% 57.8%
None 0.51 39.0 2.40e-01 96.2% 44.0%
4989274 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 40.0 3.00e-01 88.5% 40.7%
3962642 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 45.0 3.22e-01 100.0% 85.8%
4005987 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.51 40.0 2.99e-01 84.6% 77.6%
4111253 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 44.0 3.06e-01 100.0% 88.1%
3895888 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.51 39.0 2.51e-01 92.3% 29.6%
3278423 327.1.1.7 a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain › PF28778 0.51 41.0 3.93e-01 88.5% 100.0%
4192750 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.50 40.0 2.93e-01 92.3% 66.9%
4964736 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.50 43.0 3.00e-01 96.2% 47.6%
5009714 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.50 43.0 2.99e-01 96.2% 47.6%