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IMGVR_UViG_3300026465_000527-3300026465-Ga0247588_10041761

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300026465_000527-3300026465-Ga0247588_10041761 ↗
Kingdom:: archaea

Quality

89.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-63

PDB

Domain cluster: rep: MT732457.1__QQV90475.1__Harreka1_68__00068__D5-80

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00550.32 best	PP-binding	25.4	1.90e-05	93.2%	74.6%

CATH (19)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1vkuA00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.87	76.0	6.68e-01	100.0%	65.9%
4h2uD00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.85	76.0	6.91e-01	98.3%	84.6%
3ce7A00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.85	79.0	6.71e-01	100.0%	76.7%
5gxvA02	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.84	76.0	6.40e-01	100.0%	74.0%
2cgqA00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.83	74.0	6.88e-01	100.0%	78.4%
7e42A01	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.83	76.0	6.99e-01	100.0%	79.7%
2xz0D00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.80	71.0	6.38e-01	100.0%	72.0%
2n5hA00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.79	69.0	6.06e-01	100.0%	66.7%
2n50A00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.79	70.0	6.36e-01	100.0%	82.3%
1klpA00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.79	68.0	5.49e-01	100.0%	50.4%
2l22A01	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.78	68.0	5.88e-01	100.0%	62.6%
8cuyA01	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.78	65.0	6.09e-01	96.6%	74.3%
1dv5A00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.77	68.0	6.16e-01	100.0%	83.7%
6t4hA03	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.57	48.0	3.55e-01	98.3%	97.1%
1e1hB01	1.20.58.540	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	42.0	3.60e-01	83.1%	88.3%
1m6nA04	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.55	39.0	3.15e-01	81.4%	65.9%
2k53A00	1.10.3910.10	Mainly Alpha › Orthogonal Bundle › SP0561-like › SP0561-like	0.54	40.0	3.88e-01	94.9%	71.4%
1cgqA00	3.30.429.10	Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor	0.54	43.0	3.54e-01	91.5%	53.0%
8adbA01	3.90.70.120	Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A ›	0.51	42.0	2.95e-01	94.9%	54.6%

ECOD (63)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4107979	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.91	83.0	7.39e-01	100.0%	72.5%
4385875	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.89	81.0	7.23e-01	100.0%	72.5%
4476922	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.89	81.0	7.10e-01	100.0%	69.0%
3984457	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.89	81.0	7.39e-01	100.0%	77.3%
3981247	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.89	81.0	7.39e-01	100.0%	77.3%
4372392	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.89	80.0	7.17e-01	100.0%	72.5%
5079901	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	80.0	7.58e-01	100.0%	85.3%
3287432	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	81.0	7.18e-01	100.0%	72.5%
2634666	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	80.0	7.16e-01	100.0%	73.4%
3291139	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	79.0	6.95e-01	100.0%	68.2%
3353901	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.88	80.0	7.13e-01	100.0%	72.5%
4143842	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	80.0	7.19e-01	100.0%	73.8%
3374908	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	80.0	7.13e-01	100.0%	72.5%
4228180	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	79.0	7.26e-01	100.0%	77.3%
4290734	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.88	79.0	7.27e-01	100.0%	77.3%
5030544	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.87	79.0	7.09e-01	100.0%	72.5%
2428909	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.87	77.0	6.50e-01	100.0%	60.6%
3587710	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.86	77.0	6.91e-01	100.0%	72.5%
3278759	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.86	78.0	7.01e-01	100.0%	82.5%
55484	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.85	76.0	6.95e-01	100.0%	75.3%
4073207	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.85	77.0	6.77e-01	100.0%	81.2%
3952506	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.85	76.0	6.96e-01	100.0%	77.3%
3322038	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.85	74.0	7.22e-01	100.0%	87.7%
4081277	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	74.0	6.52e-01	100.0%	67.1%
2890674	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	77.0	6.35e-01	100.0%	68.3%
4570332	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	75.0	6.01e-01	100.0%	52.7%
162425	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	74.0	6.21e-01	100.0%	58.6%
3637353	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	72.0	6.23e-01	100.0%	62.2%
3287624	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.84	76.0	6.79e-01	100.0%	80.0%
4063755	327.5.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins	0.83	75.0	4.95e-01	100.0%	25.8%
3284620	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.83	73.0	6.29e-01	96.6%	64.4%
3286182	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.83	74.0	6.40e-01	100.0%	65.6%
4425670	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.82	75.0	6.11e-01	100.0%	56.2%
4109264	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.82	74.0	6.16e-01	100.0%	59.0%
5005220	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.82	73.0	6.62e-01	100.0%	76.2%
4511749	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.81	71.0	6.38e-01	96.6%	71.2%
5061121	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.81	69.0	6.36e-01	100.0%	73.3%
4400359	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.81	73.0	6.60e-01	100.0%	84.8%
3290538	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.81	73.0	6.58e-01	100.0%	85.0%
2580914	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.81	74.0	5.89e-01	100.0%	62.2%
3961057	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.80	73.0	6.27e-01	100.0%	68.9%
3961382	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.80	72.0	6.50e-01	100.0%	83.7%
4454723	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.80	69.0	6.33e-01	94.9%	85.3%
4620058	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.80	72.0	6.36e-01	100.0%	71.4%
2772214	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.80	70.0	6.40e-01	100.0%	77.2%
3180006	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.79	70.0	6.13e-01	100.0%	80.0%
3288011	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.79	71.0	6.41e-01	100.0%	88.7%
4459719	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.79	69.0	6.07e-01	100.0%	66.7%
1684875	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.79	69.0	6.06e-01	100.0%	66.7%
4888404	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.79	68.0	6.16e-01	100.0%	70.7%
3887	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.78	70.0	5.93e-01	100.0%	62.1%
3978564	132.1.1.5 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › DUF1493	0.78	69.0	5.81e-01	100.0%	91.0%
3954304	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.78	68.0	6.09e-01	100.0%	70.2%
3112152	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.77	68.0	6.32e-01	100.0%	86.8%
4662278	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.77	63.0	5.75e-01	100.0%	67.5%
4248050	132.1.1.6 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › DUF7080	0.76	64.0	5.32e-01	100.0%	54.3%
3979613	132.1.1.5 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › DUF1493	0.75	65.0	5.56e-01	100.0%	88.0%
3287939	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.75	66.0	6.00e-01	100.0%	76.2%
4012925	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.75	66.0	5.54e-01	100.0%	64.0%
4376568	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.72	61.0	5.43e-01	100.0%	72.2%
2581395	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.71	59.0	5.46e-01	100.0%	71.8%
3959014	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.69	52.0	5.52e-01	88.1%	100.0%
3490000	329.1.1.0 ↗	a+b two layers › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain	0.54	47.0	3.89e-01	100.0%	77.3%

D2 high residues 101-325

PDB

Domain cluster: representative

CATH (97)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3v8bC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.81	71.0	6.82e-01	91.6%	99.2%
2cfcA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.81	72.0	6.90e-01	92.4%	99.6%
4cqmG00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.81	70.0	7.10e-01	90.7%	99.1%
3uxyD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	7.01e-01	92.0%	99.2%
4fn4A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.91e-01	93.8%	99.2%
4dqxB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.93e-01	93.3%	98.4%
3gvcA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.94e-01	92.9%	98.8%
4z0tA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	73.0	7.12e-01	95.6%	99.2%
3gedA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.92e-01	92.0%	93.8%
2fwmX00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	7.49e-01	94.7%	100.0%
1fmcA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.81e-01	92.9%	96.1%
2dtxA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.87e-01	93.8%	96.5%
7e24A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	70.0	6.92e-01	91.6%	100.0%
8eh2A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	70.0	6.74e-01	91.1%	94.8%
5itwA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.85e-01	93.8%	99.2%
3un1C00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	7.02e-01	92.4%	98.7%
5jc8C00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.86e-01	93.3%	98.0%
6oz7B00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.97e-01	92.0%	97.9%
3oidC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.83e-01	92.0%	98.8%
5t2vA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	7.02e-01	93.3%	99.6%
5idqB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	7.31e-01	93.3%	100.0%
3awdA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.88e-01	94.7%	98.8%
2rhcA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.75e-01	92.9%	100.0%
1hxhA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	71.0	6.77e-01	92.4%	97.6%
1ae1A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	72.0	6.99e-01	94.2%	98.4%
2ag5C00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.94e-01	93.3%	99.6%
5jlaA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.78e-01	93.3%	93.8%
4e4yA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.91e-01	92.4%	99.6%
1hdcA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.85e-01	93.8%	96.4%
1e7wB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.69e-01	92.0%	98.8%
4fc7D00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.62e-01	93.3%	91.5%
8hi4A03	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	59.0	6.24e-01	76.0%	96.1%
3ai2A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	73.0	6.87e-01	95.6%	100.0%
3s55E00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	72.0	6.73e-01	94.2%	99.6%
3i4fC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.84e-01	91.6%	98.3%
4yxfB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	7.05e-01	92.0%	100.0%
3pk0D00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.75e-01	93.3%	96.1%
4lvuA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.84e-01	93.8%	97.6%
3o03A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	72.0	6.88e-01	94.7%	96.5%
3rkrA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	7.12e-01	92.0%	99.1%
3gemD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	7.19e-01	91.6%	99.5%
6pznB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.80e-01	91.1%	99.6%
6tq5A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.89e-01	92.4%	100.0%
1w6uD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.52e-01	93.8%	85.5%
3i3oG00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.93e-01	94.2%	94.3%
3svtA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.55e-01	93.3%	91.6%
1bdbA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.59e-01	92.9%	92.5%
3l77A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.99e-01	93.3%	100.0%
1oaaA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.72e-01	93.8%	100.0%
3h7aA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	69.0	7.11e-01	90.7%	99.5%
5tt0B00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	70.0	6.73e-01	92.4%	93.6%
3e9qA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	72.0	6.87e-01	95.6%	97.3%
4j2hA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	71.0	6.81e-01	94.2%	98.8%
3wtbC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.80e-01	92.4%	99.6%
2ehdA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	68.0	7.12e-01	90.2%	100.0%
3guyA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	67.0	7.06e-01	88.9%	100.0%
2q2qF00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.90e-01	93.3%	99.6%
5t5qB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	71.0	6.99e-01	94.2%	99.1%
4dyvA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	68.0	7.01e-01	90.2%	100.0%
4h15A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	71.0	6.72e-01	94.7%	97.7%
2qq5A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.85e-01	92.9%	97.9%
3o26A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	69.0	6.24e-01	92.0%	100.0%
3gdgA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.61e-01	94.2%	95.5%
1g0nB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.74e-01	93.8%	96.1%
5g4kA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.65e-01	94.7%	97.0%
1zmoA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	69.0	6.68e-01	91.6%	100.0%
2zatA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.75e-01	94.2%	99.6%
5epoA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.59e-01	93.3%	95.4%
5uzxA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	70.0	6.96e-01	93.8%	100.0%
5wqoB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	69.0	7.03e-01	92.9%	100.0%
6m5nA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	70.0	6.61e-01	94.2%	99.6%
3e03A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	70.0	6.59e-01	94.7%	98.9%
1o5iA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	70.0	6.95e-01	94.7%	100.0%
5z2lA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	68.0	6.71e-01	92.0%	97.5%
1zmtA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	67.0	6.46e-01	90.7%	96.4%
4o6vA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	69.0	6.87e-01	93.3%	100.0%
5bt9D00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	69.0	6.69e-01	93.3%	96.3%
3edmD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	68.0	7.02e-01	92.0%	99.5%
3l6eA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	67.0	6.94e-01	90.7%	99.5%
4zrmA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.76	65.0	6.91e-01	88.9%	100.0%
4impA02	3.40.50.11460	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.76	64.0	6.66e-01	100.0%	94.8%
5idyA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.76	69.0	6.51e-01	95.6%	98.9%
3qivA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.75	63.0	6.73e-01	90.7%	99.5%
1rkxA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.74	55.0	5.99e-01	76.4%	97.9%
3vvbA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.74	66.0	6.22e-01	94.7%	88.5%
2pzmB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.72	64.0	5.68e-01	93.8%	87.2%
1xq6A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.71	64.0	6.12e-01	94.7%	99.6%
1qydA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.71	56.0	6.03e-01	94.2%	96.3%
2ozlB02	3.40.50.920	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.70	39.0	5.01e-01	84.9%	91.0%
3oh8A02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.70	63.0	5.99e-01	94.7%	95.8%
2bkaA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.69	62.0	6.19e-01	93.8%	97.0%
5f5nA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	59.0	5.42e-01	92.0%	92.0%
4jgbB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	59.0	6.15e-01	90.7%	100.0%
2x4gA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.66	58.0	5.25e-01	92.9%	90.1%
3hwwA01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.59	42.0	4.46e-01	85.8%	80.9%
2c5sA02	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.57	39.0	4.10e-01	81.8%	75.4%
2panA01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.57	41.0	4.64e-01	85.8%	97.1%

ECOD (97)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3290122	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.87	73.0	7.69e-01	99.1%	94.6%
3956046	2003.1.1.85 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › SpnB_Rossmann	0.83	69.0	6.98e-01	100.0%	87.3%
4025345	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.82	77.0	6.78e-01	97.3%	84.5%
3693683	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.82	72.0	6.91e-01	90.7%	99.2%
3727011	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.82	73.0	7.28e-01	92.4%	100.0%
3727820	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.81	73.0	6.61e-01	93.3%	95.9%
3353393	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.81	76.0	6.93e-01	98.2%	88.8%
147273	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.81	72.0	6.82e-01	92.4%	99.2%
3265070	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.81	73.0	6.64e-01	93.8%	94.7%
3427053	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	75.0	6.40e-01	98.2%	83.2%
3684824	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.80e-01	93.3%	93.9%
1201336	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.96e-01	93.3%	98.0%
3882009	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	70.0	7.08e-01	91.1%	100.0%
4527528	2003.1.1.4 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.80	70.0	7.08e-01	91.1%	98.7%
3258703	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	76.0	6.73e-01	98.7%	91.5%
3974378	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	72.0	6.94e-01	93.8%	94.0%
3955827	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	73.0	6.49e-01	95.1%	99.3%
134055	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	71.0	6.92e-01	92.0%	93.8%
3498407	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	75.0	6.61e-01	98.7%	84.4%
3281613	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	71.0	6.92e-01	92.9%	100.0%
None	—		0.80	72.0	6.87e-01	93.3%	96.0%
5039873	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	71.0	6.59e-01	92.0%	89.3%
3193257	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	72.0	6.74e-01	94.2%	93.3%
4247979	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.89e-01	93.3%	99.2%
1827831	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	71.0	7.31e-01	93.3%	100.0%
4955724	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.86e-01	93.8%	99.6%
4955651	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.69e-01	93.3%	92.2%
3974472	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.80	71.0	6.86e-01	92.9%	100.0%
3958789	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.80	62.0	6.77e-01	80.0%	97.4%
4640210	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	72.0	6.74e-01	93.8%	97.4%
4962100	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	71.0	6.57e-01	92.9%	92.7%
4257645	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	71.0	6.75e-01	92.4%	98.0%
147687	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	72.0	6.88e-01	94.7%	98.8%
5066650	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.80	71.0	6.76e-01	93.3%	96.2%
3734766	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.80	70.0	6.95e-01	92.0%	100.0%
3481224	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.79	75.0	6.63e-01	98.7%	85.8%
5025515	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.85e-01	93.8%	99.2%
3789656	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.79	70.0	6.74e-01	91.6%	99.6%
1828999	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.78e-01	93.3%	93.8%
4942948	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	71.0	7.01e-01	93.8%	98.8%
135817	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	70.0	6.82e-01	91.6%	98.3%
3689670	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	71.0	6.44e-01	93.8%	89.5%
5083641	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	70.0	6.67e-01	92.0%	94.6%
5015132	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	72.0	7.14e-01	93.8%	97.8%
None	—		0.79	71.0	6.39e-01	93.3%	85.2%
3916412	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.47e-01	93.8%	86.9%
148422	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	70.0	6.83e-01	91.6%	98.3%
4563192	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	71.0	6.64e-01	92.9%	96.6%
3722501	2003.1.1.148 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR	0.79	71.0	6.54e-01	93.8%	88.2%
3259287	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.35e-01	93.3%	87.7%
4851384	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	60.0	6.26e-01	76.9%	96.6%
3441485	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	72.0	6.59e-01	94.7%	96.4%
3251614	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.71e-01	93.3%	99.6%
4963069	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.99e-01	92.9%	98.3%
3866190	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.34e-01	93.8%	84.5%
3656550	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	70.0	6.94e-01	92.9%	99.1%
4524377	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	70.0	7.11e-01	92.0%	100.0%
5047359	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.63e-01	93.8%	94.1%
4444238	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	71.0	6.42e-01	94.2%	88.7%
3258398	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	72.0	6.56e-01	95.1%	95.1%
3287034	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	70.0	6.64e-01	93.3%	95.8%
1918551	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	70.0	6.70e-01	92.4%	93.7%
3460340	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.79	62.0	6.46e-01	80.9%	92.4%
3956301	2003.1.1.142 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR, adh_short_C2	0.79	71.0	6.88e-01	94.7%	100.0%
3913496	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.79	71.0	6.70e-01	94.7%	95.5%
3970796	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.79	69.0	6.86e-01	91.6%	98.7%
3960307	2003.1.1.85 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › SpnB_Rossmann	0.78	61.0	6.73e-01	99.6%	97.8%
3684958	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.78	71.0	6.46e-01	94.2%	88.8%
3282577	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.78	69.0	6.83e-01	91.6%	100.0%
3279172	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.78	72.0	6.67e-01	96.0%	88.7%
None	—		0.78	71.0	6.47e-01	94.2%	87.0%
3734728	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.78	67.0	6.37e-01	88.4%	92.5%
3689294	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.78	70.0	6.34e-01	93.3%	97.2%
3629043	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.78	70.0	6.02e-01	94.7%	91.8%
4943308	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.78	69.0	6.57e-01	92.9%	96.2%
3185890	2003.1.1.352 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, Epimerase, adh_short_C2	0.78	70.0	6.44e-01	93.8%	96.0%
3723428	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.78	68.0	6.60e-01	92.0%	96.8%
3279980	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.77	69.0	6.23e-01	93.8%	91.3%
4021188	129.1.1.0 ↗	alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like	0.77	61.0	6.71e-01	100.0%	98.9%
1884917	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.77	71.0	6.68e-01	95.6%	99.6%
3720862	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.77	73.0	6.52e-01	100.0%	98.3%
3696146	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.76	72.0	6.28e-01	100.0%	99.7%
3281158	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.76	67.0	6.60e-01	92.9%	93.8%
4369824	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.75	66.0	6.44e-01	91.6%	98.4%
3222803	2003.1.1.20 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase	0.75	69.0	6.16e-01	96.4%	83.3%
4204486	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.74	65.0	6.71e-01	92.0%	97.2%
5056517	2003.1.1.20 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase	0.74	66.0	5.80e-01	92.4%	89.8%
5039532	2003.1.1.20 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase	0.73	65.0	5.67e-01	93.3%	86.8%
4360353	2003.1.1.120 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD-bd_HRPKS_sdrA	0.73	59.0	6.37e-01	100.0%	98.9%
4000799	2003.1.1.11 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD	0.72	65.0	5.40e-01	93.3%	86.8%
328816	2003.1.1.20 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase	0.71	63.0	5.62e-01	92.4%	87.4%
3962239	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.71	58.0	6.19e-01	93.3%	96.9%
3691979	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.71	63.0	6.27e-01	93.8%	90.9%
3332806	2003.1.1.12 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DapB_N	0.71	50.0	5.47e-01	92.4%	86.2%
3724770	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.69	54.0	5.98e-01	84.4%	98.9%
4972423	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.66	47.0	5.27e-01	90.2%	92.0%
4536847	2005.1.1.23 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA_Me_trans	0.52	40.0	4.11e-01	84.4%	82.3%

D3 high residues 637-793

PDB

Domain cluster: rep: CAKLQF020000007.1__CAH1081736.1__SAMEA5780031_01690__00096__D5-133

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF21089.4 best	PKS_DH_N	37.9	2.00e-09	65.6%	87.4%

CATH (65)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3lbeB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.87	66.0	7.42e-01	91.7%	97.6%
2fs2B00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.86	68.0	7.30e-01	92.4%	92.8%
2dslA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.86	62.0	7.20e-01	86.0%	100.0%
3b7kC02	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.85	59.0	7.03e-01	74.5%	100.0%
3lw3B00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.85	65.0	6.98e-01	94.3%	90.5%
3d6xB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	71.0	7.54e-01	91.1%	97.1%
2gvhB02	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	60.0	6.95e-01	80.3%	97.4%
4ybvA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	63.0	7.23e-01	86.0%	100.0%
3kg8A01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	67.0	7.32e-01	92.4%	99.2%
3e29B00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	67.0	7.23e-01	91.7%	96.3%
3e1eC00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.84	69.0	7.26e-01	92.4%	94.3%
4k02A00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.83	65.0	7.22e-01	87.9%	100.0%
2cy9B00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.83	66.0	7.24e-01	91.1%	98.5%
3s4kA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.82	63.0	7.03e-01	87.3%	98.4%
1zkiA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.82	64.0	7.14e-01	91.1%	100.0%
3dkzA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.82	63.0	7.06e-01	91.1%	99.2%
1z6bA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.82	68.0	7.17e-01	91.1%	95.1%
1yliB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.80	59.0	6.10e-01	79.6%	79.7%
4mtuA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.80	62.0	6.47e-01	79.0%	89.5%
2qwzA01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.79	65.0	7.04e-01	91.7%	100.0%
5byuA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.79	56.0	6.21e-01	80.3%	89.1%
4ae8D00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.79	65.0	6.36e-01	90.4%	80.6%
2pzhA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.78	58.0	6.32e-01	82.8%	90.3%
4w78F00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	57.0	6.37e-01	75.8%	96.9%
3qooA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	59.0	6.36e-01	79.6%	91.0%
3f1tB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	62.0	6.66e-01	90.4%	96.3%
2hljA01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	56.0	6.04e-01	80.3%	85.4%
2cwzA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	58.0	6.27e-01	80.3%	89.1%
5eo4A01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.77	57.0	6.06e-01	82.2%	85.6%
2fujA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.76	55.0	6.30e-01	81.5%	97.5%
1lo7A00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.76	60.0	6.39e-01	81.5%	91.4%
2gvhC01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.76	54.0	5.78e-01	79.0%	83.8%
3kg6C00	3.10.129.110	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase	0.75	67.0	5.45e-01	93.6%	95.3%
3hm0A00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.75	57.0	6.31e-01	81.5%	96.8%
5egjA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.75	63.0	6.13e-01	86.6%	91.6%
3kuvB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.75	57.0	6.23e-01	79.6%	93.2%
2v1oB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.74	59.0	6.12e-01	81.5%	100.0%
5e1vB00	3.10.129.110	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase	0.74	60.0	4.88e-01	84.1%	95.6%
1y7uA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.74	62.0	6.13e-01	86.6%	93.3%
4ae7A00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.74	65.0	6.09e-01	91.7%	80.1%
3ir3A00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.74	56.0	6.25e-01	91.1%	97.6%
4ienA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.73	62.0	6.32e-01	87.9%	97.4%
3hduA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.72	64.0	6.50e-01	91.7%	96.1%
2nujA01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.72	59.0	6.08e-01	84.1%	89.9%
4rljA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.72	54.0	5.69e-01	77.7%	97.2%
3b7kB01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.72	57.0	6.10e-01	82.8%	99.3%
2q2bA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.71	59.0	6.30e-01	86.6%	97.2%
5tz6B02	3.10.129.120	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A ›	0.71	61.0	6.17e-01	94.3%	91.6%
3kg7B00	3.10.129.110	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase	0.71	62.0	5.01e-01	93.0%	93.3%
2pfcA00	3.10.129.30	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Rv0098, thioesterase-like hot dog domain	0.68	59.0	5.87e-01	91.1%	98.8%
2bi0A02	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.68	58.0	5.97e-01	91.1%	94.6%
3omlA03	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.67	56.0	4.64e-01	86.0%	97.7%
6obtA00	3.10.129.110	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase	0.67	63.0	5.15e-01	100.0%	94.4%
2w3xB00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.65	50.0	5.21e-01	85.4%	86.8%
3u0aA00	2.40.160.210	Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain	0.63	56.0	4.64e-01	92.4%	78.9%
1pn2B01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.63	49.0	5.10e-01	81.5%	100.0%
4qfwA00	2.40.160.210	Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain	0.62	52.0	4.34e-01	88.5%	52.9%
4hzoA00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.62	51.0	4.04e-01	86.0%	48.5%
1c8uA01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.62	52.0	5.30e-01	90.4%	98.7%
3kh8B01	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.61	50.0	5.10e-01	85.4%	95.5%
4k7rA02	2.20.200.10	Mainly Beta › Single Sheet › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP)	0.58	29.0	3.97e-01	78.3%	96.1%
1nqnA00	2.40.128.30	Mainly Beta › Beta Barrel › Lipocalin › Avidin-like	0.56	35.0	4.00e-01	89.2%	83.1%
2vf9A00	3.30.380.10	Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein	0.51	35.0	3.76e-01	98.7%	83.2%
1aq3A00	3.30.380.10	Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein	0.50	34.0	3.70e-01	98.1%	82.9%
4bj8K00	2.40.128.30	Mainly Beta › Beta Barrel › Lipocalin › Avidin-like	0.50	35.0	4.01e-01	89.8%	95.0%

ECOD (84)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3291314	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.93	64.0	7.70e-01	76.4%	100.0%
3284607	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.91	57.0	7.25e-01	70.1%	100.0%
4446241	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.86	72.0	7.49e-01	90.4%	93.1%
4446229	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.86	69.0	7.55e-01	82.8%	100.0%
174766	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.84	63.0	7.19e-01	82.8%	100.0%
119430	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.84	65.0	7.28e-01	89.8%	100.0%
4466408	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.84	69.0	7.12e-01	89.2%	89.3%
3886961	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.84	62.0	7.11e-01	92.4%	100.0%
4286606	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.83	70.0	7.18e-01	89.8%	90.7%
3387730	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.83	61.0	6.61e-01	78.3%	87.4%
4560358	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.83	68.0	7.21e-01	91.1%	95.0%
3284169	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.83	67.0	7.15e-01	92.4%	94.3%
3970758	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.83	60.0	6.68e-01	79.6%	92.0%
224845	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.83	65.0	7.22e-01	87.9%	100.0%
4100963	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.83	71.0	7.45e-01	90.4%	97.2%
4356793	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.82	60.0	6.77e-01	79.0%	94.4%
4016948	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.82	70.0	7.20e-01	92.4%	92.7%
4664187	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.82	72.0	7.26e-01	94.9%	92.3%
336675	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.82	60.0	6.34e-01	79.6%	83.1%
4525648	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.82	70.0	7.44e-01	93.0%	100.0%
3182903	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.81	68.0	7.21e-01	86.6%	100.0%
3189836	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.81	72.0	7.07e-01	91.7%	94.5%
4620763	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.81	61.0	6.88e-01	77.1%	98.4%
3693742	222.1.1.10 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT_3	0.81	65.0	7.14e-01	93.0%	100.0%
4347156	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.81	67.0	7.23e-01	95.5%	100.0%
4012208	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.81	68.0	6.99e-01	96.2%	91.3%
3209799	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.81	68.0	7.22e-01	95.5%	97.9%
4531957	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.81	69.0	7.04e-01	87.9%	95.3%
3680278	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.81	65.0	6.56e-01	90.4%	83.0%
3277920	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.80	62.0	6.77e-01	86.6%	96.2%
4021640	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.80	69.0	6.92e-01	89.8%	90.6%
4012933	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.80	68.0	7.25e-01	93.6%	100.0%
4398275	2007.1.19.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like	0.80	69.0	4.31e-01	89.8%	19.6%
3286194	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.79	66.0	7.03e-01	92.4%	97.1%
3744131	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.79	67.0	6.96e-01	92.4%	94.5%
4429745	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.79	67.0	6.88e-01	87.9%	93.3%
3959737	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.79	65.0	6.86e-01	97.5%	95.7%
3263236	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.79	68.0	6.97e-01	92.4%	93.3%
4017016	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	68.0	7.06e-01	89.8%	97.2%
4608460	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	74.0	7.21e-01	99.4%	98.8%
2996025	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	62.0	6.50e-01	91.7%	90.2%
4217489	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	66.0	7.04e-01	87.9%	100.0%
4225086	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	70.0	6.93e-01	98.7%	89.7%
4016704	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.78	69.0	6.95e-01	91.7%	93.5%
4346913	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.77	69.0	7.00e-01	93.6%	97.4%
6057	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.77	54.0	5.84e-01	78.3%	83.7%
3635424	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.76	68.0	5.90e-01	93.0%	83.1%
3744610	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.76	67.0	6.35e-01	91.7%	82.2%
3781358	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.76	67.0	6.37e-01	93.0%	83.6%
4029391	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.75	63.0	6.32e-01	89.8%	86.1%
3741415	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.75	68.0	6.50e-01	93.6%	84.6%
5062019	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	62.0	6.49e-01	86.0%	100.0%
4562002	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	62.0	6.31e-01	86.6%	96.1%
4308071	222.1.1.17 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N	0.74	70.0	6.97e-01	99.4%	96.9%
3864703	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	63.0	6.00e-01	87.9%	91.1%
3529054	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	61.0	5.84e-01	85.4%	80.0%
71646	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	62.0	6.31e-01	86.6%	97.4%
3551948	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	63.0	6.28e-01	87.9%	96.2%
5012014	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	61.0	5.98e-01	86.0%	87.6%
6054	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	62.0	6.27e-01	86.6%	96.1%
3898226	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.74	62.0	6.00e-01	86.6%	91.8%
3857561	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.74	61.0	5.81e-01	86.0%	79.4%
4017019	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.73	65.0	6.06e-01	93.6%	81.1%
3615703	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.73	60.0	5.86e-01	85.4%	89.4%
3796586	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.73	61.0	5.69e-01	86.0%	76.2%
3710825	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.72	58.0	5.51e-01	84.7%	85.4%
3928775	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.72	60.0	5.67e-01	86.0%	80.0%
3898227	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.72	60.0	5.90e-01	86.0%	88.5%
4026705	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.72	60.0	5.61e-01	86.0%	74.5%
3599546	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.71	59.0	5.84e-01	86.0%	95.8%
4184669	222.1.1.12 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH	0.70	62.0	5.96e-01	92.4%	86.9%
4345385	222.1.1.12 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH	0.70	61.0	5.83e-01	92.4%	86.7%
4016965	222.1.1.12 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH	0.70	60.0	5.68e-01	90.4%	81.6%
3241824	222.1.1.15 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT_3C	0.70	62.0	5.69e-01	92.4%	76.4%
3618440	222.1.1.15 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT_3C	0.70	61.0	5.75e-01	91.7%	79.5%
4451002	222.1.1.12 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH	0.70	60.0	5.74e-01	91.1%	81.1%
3444227	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.69	60.0	5.36e-01	90.4%	81.9%
3249129	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.69	62.0	5.75e-01	94.9%	99.5%
3814550	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.69	62.0	5.57e-01	94.9%	99.0%
3510841	222.1.1.3 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › Acyl_CoA_thio	0.69	61.0	5.84e-01	92.4%	89.7%
3241156	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.69	63.0	5.67e-01	96.8%	94.8%
4526897	222.1.1.12 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH	0.68	60.0	5.65e-01	93.0%	85.9%
3857562	222.1.1.0 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase	0.68	64.0	5.65e-01	99.4%	94.4%
3734793	222.1.1.15 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT_3C	0.64	55.0	5.17e-01	93.0%	86.7%

D4 medium residues 379-431

PDB

Domain cluster: representative

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2efeA01	1.10.246.120	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 ›	0.74	63.0	5.55e-01	98.1%	76.5%
4a3vB01	1.10.8.60	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.69	47.0	4.35e-01	73.6%	54.2%
3nrgA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.68	50.0	3.27e-01	77.4%	47.0%
1tfeA02	1.10.286.20	Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 ›	0.68	49.0	5.19e-01	81.1%	95.6%
7wboA01	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.64	51.0	3.66e-01	96.2%	94.4%
2lqxA00	6.10.250.1700	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.64	41.0	4.42e-01	84.9%	85.4%
2aj6A00	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.62	48.0	3.84e-01	88.7%	39.2%
3ff5A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	43.0	4.36e-01	98.1%	75.9%
4a17U01	1.10.287.310	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.60	52.0	4.61e-01	98.1%	79.2%
4azsA03	1.10.510.10	Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1	0.59	47.0	3.54e-01	90.6%	62.0%
3ismC01	1.25.40.240	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain	0.59	49.0	3.54e-01	92.5%	42.9%
7kpsB01	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.57	48.0	3.28e-01	92.5%	38.0%
3cl3A01	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.57	40.0	3.56e-01	100.0%	47.6%
7s0rB01	1.20.81.20	Mainly Alpha › Up-down Bundle › Receptor-associated Protein ›	0.55	40.0	3.65e-01	83.0%	59.2%
2bduA02	1.10.150.340	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain	0.54	48.0	4.27e-01	98.1%	100.0%
3ivpD01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.54	41.0	3.62e-01	81.1%	66.7%
6n59A01	3.10.20.740	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.53	42.0	3.18e-01	84.9%	73.0%
4is7A02	1.10.150.50	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1	0.52	46.0	4.17e-01	100.0%	86.1%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3505845	101.1.2.407 ↗	alpha arrays › HTH › HTH › winged helix domain › WHD_ORC2	0.85	58.0	4.64e-01	71.7%	38.0%
3316223	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.81	61.0	4.81e-01	81.1%	41.0%
4027192	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.80	59.0	4.78e-01	79.2%	42.0%
4318142	230.3.1.1 ↗	a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS	0.66	52.0	3.93e-01	90.6%	44.3%
3420806	102.1.1.0 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like	0.65	48.0	4.07e-01	79.2%	57.8%
3460419	103.1.1.0 ↗	alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain	0.60	44.0	4.27e-01	79.2%	71.7%
3412555	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.59	48.0	3.75e-01	88.7%	48.2%
3628378	192.15.1.0 ↗	alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains	0.58	40.0	2.80e-01	71.7%	23.0%
4975876	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.57	46.0	2.87e-01	98.1%	51.9%
3184934	101.1.4.0 ↗	alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like	0.55	37.0	3.72e-01	71.7%	78.2%
2814626	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.54	39.0	2.48e-01	79.2%	23.3%
3607140	601.48.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain	0.54	35.0	3.52e-01	77.4%	65.5%
3243936	192.8.1.390 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CDK2AP	0.53	42.0	3.78e-01	92.5%	68.8%
3821041	4958.1.1.1 ↗	a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4	0.52	42.0	2.80e-01	92.5%	50.2%
3219915	2485.1.1.49 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_12	0.52	45.0	3.16e-01	100.0%	97.2%

D5 medium residues 536-629

PDB

Domain cluster: representative

CATH (24)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4impA03	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.84	78.0	5.54e-01	100.0%	39.5%
3qp9D00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.80	74.0	4.65e-01	100.0%	22.1%
4j1qA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.79	73.0	4.65e-01	98.9%	23.5%
4iiuC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.78	68.0	4.94e-01	93.6%	38.3%
1bdbA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.76	67.0	4.76e-01	94.7%	37.8%
5iz4A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.76	66.0	4.79e-01	94.7%	35.6%
3gemD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.76	56.0	4.24e-01	96.8%	34.1%
5bt9D00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.74	65.0	4.76e-01	95.7%	36.9%
3gedA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.72	63.0	4.59e-01	96.8%	36.8%
1dhrA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	62.0	4.57e-01	98.9%	40.7%
3i4fC00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	60.0	4.34e-01	93.6%	37.5%
6ecpB01	3.40.50.10860	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1	0.60	34.0	2.95e-01	80.9%	34.5%
2c2xA02	3.40.50.10860	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1	0.59	33.0	2.88e-01	75.5%	33.1%
1pjcA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.58	44.0	3.59e-01	80.9%	75.6%
7uvpA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	41.0	3.06e-01	79.8%	88.7%
6a8mA01	3.40.350.10	Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain	0.54	40.0	3.31e-01	78.7%	90.1%
5b7yA00	3.20.20.150	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes	0.53	39.0	2.86e-01	77.7%	58.0%
4us5C00	3.20.20.30	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain	0.53	38.0	2.67e-01	76.6%	86.7%
1vz0A01	3.90.1530.30	Alpha Beta › Alpha-Beta Complex › Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain ›	0.53	27.0	3.27e-01	81.9%	74.6%
7lgnB03	3.90.190.20	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain	0.52	40.0	3.57e-01	85.1%	79.0%
2px0A02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	40.0	3.18e-01	85.1%	41.6%
5t3yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	35.0	3.21e-01	77.7%	53.6%
7t85A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	39.0	3.29e-01	84.0%	48.4%
4dqlA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.50	36.0	3.01e-01	74.5%	55.9%

ECOD (26)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3271719	2003.1.5.408 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › KR	0.89	85.0	5.14e-01	100.0%	20.0%
4565941	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.88	83.0	5.67e-01	100.0%	37.2%
3277826	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.87	80.0	5.65e-01	97.9%	35.4%
3284602	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.86	77.0	5.11e-01	94.7%	27.5%
3738260	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.86	72.0	5.23e-01	88.3%	37.4%
3960758	2003.1.1.152 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR, GDP_Man_Dehyd	0.86	81.0	5.66e-01	100.0%	38.5%
None	—		0.82	76.0	5.47e-01	100.0%	40.8%
4581939	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.81	76.0	5.33e-01	100.0%	39.6%
143212	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.81	75.0	5.30e-01	100.0%	39.2%
4419487	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.80	74.0	5.72e-01	100.0%	50.3%
3949961	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.79	75.0	5.29e-01	100.0%	38.8%
3729956	2003.1.1.148 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR	0.79	66.0	4.65e-01	89.4%	32.0%
3934366	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.79	70.0	4.68e-01	94.7%	40.6%
1514718	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.77	68.0	4.96e-01	98.9%	37.5%
3967292	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.76	61.0	4.48e-01	85.1%	37.4%
3729630	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.76	69.0	5.92e-01	98.9%	66.9%
1890683	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.76	66.0	4.83e-01	95.7%	37.8%
5010650	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.74	65.0	4.82e-01	98.9%	39.6%
4023274	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.73	67.0	4.70e-01	100.0%	40.3%
3952427	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.73	65.0	4.61e-01	96.8%	38.1%
3640960	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.70	58.0	4.59e-01	90.4%	50.3%
3558964	2007.1.6.2 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain › THF_DHG_CYH	0.59	33.0	2.90e-01	75.5%	34.0%
3626505	2496.1.1.0 ↗	a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like	0.58	41.0	3.48e-01	74.5%	63.7%
327695	2004.1.1.43 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54	0.51	40.0	3.09e-01	85.1%	37.9%
4369666	2004.1.1.43 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54	0.51	40.0	3.13e-01	85.1%	39.0%
4345012	2004.1.1.43 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54	0.50	39.0	2.93e-01	85.1%	34.2%