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IMGVR_UViG_3300027677_000185-3300027677-Ga0209019_10093961

Arc-Vir

IMGVR_UViG_3300027677_000185-3300027677-Ga0209019_10093961

Identity

Kingdom:
archaea

Quality

84.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 476-550
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6cxtB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.65 45.0 3.98e-01 72.0% 78.6%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 47.0 3.91e-01 86.7% 88.5%
3lxzB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 44.0 3.69e-01 82.7% 85.5%
2da3A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.58 34.0 3.95e-01 78.7% 91.5%
1le8A00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.55 33.0 3.71e-01 78.7% 83.0%
1e3oC02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.55 33.0 3.82e-01 81.3% 93.8%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 42.0 3.52e-01 89.3% 75.2%
2jifA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.52 38.0 3.37e-01 80.0% 79.7%
1zq3P00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.51 33.0 3.41e-01 96.0% 70.6%
3osgA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.51 30.0 3.26e-01 80.0% 70.0%
1k78A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 29.0 3.10e-01 80.0% 63.6%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.50 40.0 2.33e-01 86.7% 93.9%
2wh5A00 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.50 34.0 3.29e-01 72.0% 72.2%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3599005 4033.1.1.0 ↗ alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like 0.63 45.0 3.82e-01 74.7% 74.4%
3389359 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.63 36.0 4.28e-01 73.3% 95.3%
3802856 145.1.1.1 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.61 33.0 3.75e-01 78.7% 70.9%
3215782 4033.1.1.1 ↗ alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.61 44.0 3.83e-01 78.7% 76.8%
1828113 4033.1.1.1 ↗ alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.59 42.0 3.59e-01 78.7% 71.5%
3669646 101.1.1.1 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.56 36.0 4.01e-01 86.7% 89.1%
3691453 4033.1.1.1 ↗ alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.56 40.0 3.49e-01 77.3% 77.6%
4510292 3455.1.1.0 ↗ alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.56 38.0 3.85e-01 90.7% 72.0%
5068826 4033.1.1.1 ↗ alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.55 40.0 3.49e-01 78.7% 79.2%
3201922 101.1.3.15 ↗ alpha arrays › HTH › HTH › tetra-helical, LuxR-like › Myb_DNA-binding 0.54 32.0 3.45e-01 88.0% 67.7%
3932119 574.1.1.1 ↗ alpha bundles › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp 0.54 47.0 4.54e-01 97.3% 87.1%
3515076 101.1.1.3 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding 0.54 30.0 2.95e-01 80.0% 47.5%
3185929 101.1.1.3 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding 0.53 33.0 3.30e-01 90.7% 58.7%
3646708 101.1.1.1 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.53 34.0 2.98e-01 89.3% 42.6%
3227458 101.1.1.1 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.52 38.0 4.09e-01 89.3% 96.7%
3214086 226.1.1.1 ↗ a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.51 42.0 3.01e-01 93.3% 85.6%
3205865 101.1.1.67 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_6 0.51 36.0 3.25e-01 100.0% 51.8%
4942666 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.51 38.0 2.95e-01 82.7% 48.1%
3893326 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.50 37.0 2.73e-01 93.3% 29.5%
D2 medium residues 16-99
PDB
Domain cluster: rep: IMGVR_UViG_3300021513_000102-3300021513-Ga0190315_10005481__D86-160
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01022.27 best HTH_5 23.7 4.80e-05 56.0% 91.5%
D3 medium residues 100-228
PDB
Domain cluster: rep: IMGVR_UViG_3300047461_000409-3300047461-Ga0494480_0005191_3837_6272__D76-111_129-153_167-210
D4 medium residues 261-298_362-467
PDB
Domain cluster: representative
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ewvA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 61.0 5.13e-01 91.0% 78.8%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 62.0 5.35e-01 97.2% 88.6%
1q6zA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.67 52.0 4.83e-01 82.6% 85.9%
4ceiB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 50.0 4.62e-01 78.5% 100.0%
4w7sA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 50.0 4.06e-01 78.5% 70.1%
6jdrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 50.0 5.02e-01 81.2% 93.0%
4q6bA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 47.0 4.26e-01 77.8% 99.0%
4gkbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 51.0 4.32e-01 91.7% 93.9%
4h51A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 52.0 4.28e-01 93.8% 69.9%
5c5cA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 50.0 4.81e-01 88.9% 95.1%
3hutA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 45.0 4.07e-01 77.1% 99.0%
4j1qA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 50.0 3.69e-01 91.7% 56.8%
4jc8A01 3.40.50.2060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 1 0.60 42.0 4.33e-01 72.2% 90.4%
3h75A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 47.0 4.27e-01 83.3% 89.4%
6jimB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 51.0 5.17e-01 93.8% 100.0%
2qq6A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.59 48.0 3.94e-01 86.8% 85.4%
3d2lC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 45.0 4.25e-01 81.2% 83.1%
3my7A02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.59 50.0 4.62e-01 93.8% 98.9%
4j3fA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 48.0 4.06e-01 90.3% 92.3%
3vzpC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 48.0 4.09e-01 89.6% 95.5%
1bgvA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 43.0 4.16e-01 78.5% 98.2%
2c20A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 48.0 4.34e-01 91.0% 99.0%
3iacC01 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.57 46.0 3.45e-01 86.8% 90.9%
1ws6A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 44.0 4.23e-01 82.6% 86.5%
7d27A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.57 51.0 4.42e-01 100.0% 96.5%
2fpoC00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 44.0 4.15e-01 82.6% 85.6%
1wueA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.56 46.0 4.03e-01 88.9% 94.1%
2pjdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.10e-01 82.6% 85.9%
3pffA05 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.56 44.0 4.11e-01 82.6% 77.1%
3k4hB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 45.0 4.56e-01 87.5% 88.0%
5gvrA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 3.93e-01 91.0% 75.6%
2q01A01 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 46.0 3.46e-01 92.4% 90.7%
5d84A02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 31.0 3.48e-01 81.9% 71.2%
4xxhA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 44.0 4.47e-01 86.8% 89.1%
5cvcA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 29.0 3.44e-01 82.6% 75.3%
5ej8A02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.55 41.0 4.36e-01 93.8% 92.1%
1v4vA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 44.0 4.31e-01 91.7% 79.6%
7u35A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 34.0 4.11e-01 83.3% 97.8%
6xl1A01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.54 48.0 4.69e-01 95.8% 92.3%
5lqdD01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 41.0 3.57e-01 82.6% 94.6%
3dz1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 47.0 3.80e-01 100.0% 90.0%
5vogA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 38.0 3.63e-01 74.3% 80.7%
1jx6A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 45.0 4.23e-01 93.1% 97.8%
5i7wA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 30.0 3.42e-01 84.7% 71.9%
1qv9A01 3.40.50.10830 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) 0.53 44.0 4.39e-01 91.7% 97.4%
3qldA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.53 43.0 3.72e-01 88.9% 90.0%
2ajtA01 3.40.50.10940 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 41.0 3.87e-01 82.6% 92.6%
4b3fX01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 3.48e-01 93.8% 69.2%
3r64A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 41.0 3.28e-01 94.4% 41.8%
1u04A03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 38.0 3.58e-01 83.3% 61.2%
1g8kA03 3.40.228.10 Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 0.51 41.0 3.50e-01 86.8% 86.2%
4wqmA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.51 38.0 4.01e-01 78.5% 96.2%
3cg4A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 39.0 4.15e-01 81.9% 92.9%
2e11A00 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.51 40.0 3.38e-01 86.1% 89.8%
5tqjA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 39.0 4.21e-01 82.6% 100.0%
1w96C01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 36.0 3.46e-01 72.2% 88.5%
3cvjC00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.50 43.0 3.72e-01 95.8% 85.1%
4mwaA00 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.50 44.0 3.69e-01 97.9% 91.9%
5t3yA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 40.0 4.21e-01 84.0% 96.8%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3966741 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 62.0 4.69e-01 91.0% 57.4%
4135753 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.73 62.0 4.61e-01 91.0% 56.2%
2554619 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.71 61.0 4.50e-01 91.0% 54.6%
5025215 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.70 64.0 4.67e-01 99.3% 55.9%
5012452 2004.1.1.1222 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27713 0.70 59.0 5.43e-01 91.0% 85.1%
4990161 2004.1.1.123 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_RecD 0.70 54.0 4.54e-01 81.2% 68.3%
4989677 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 63.0 5.87e-01 97.2% 88.0%
4248117 2004.1.1.28 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK 0.67 52.0 5.26e-01 80.6% 96.4%
3163557 2004.1.1.123 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_RecD 0.67 52.0 4.77e-01 81.2% 71.4%
4969466 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 51.0 4.90e-01 82.6% 72.7%
1653220 2007.1.2.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_1 0.63 39.0 4.34e-01 73.6% 79.5%
3830193 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.62 43.0 4.51e-01 75.7% 76.3%
4995496 2004.1.1.103 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sua5_C 0.61 40.0 4.60e-01 75.7% 95.0%
3341460 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.60 47.0 4.17e-01 81.9% 66.3%
3259418 2003.6.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.60 51.0 3.69e-01 92.4% 78.3%
3587067 2007.1.4.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › DAGK_cat 0.60 42.0 4.52e-01 89.6% 85.8%
3218897 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.59 42.0 4.30e-01 72.9% 87.1%
3740223 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.58 41.0 4.27e-01 72.2% 93.8%
3685952 2007.1.7.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH 0.56 41.0 4.01e-01 76.4% 90.0%
5028035 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.55 45.0 4.23e-01 89.6% 98.9%
3691484 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 48.0 4.11e-01 94.4% 60.9%
3601038 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 47.0 4.32e-01 93.8% 82.1%
5068949 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.55 47.0 4.02e-01 94.4% 93.2%
3687689 207.1.1.79 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › F-box 0.54 40.0 3.10e-01 78.5% 62.1%
4363528 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 45.0 4.42e-01 92.4% 98.1%
2389059 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.54 43.0 3.69e-01 86.8% 90.8%
4958041 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.53 41.0 3.37e-01 81.2% 91.5%
4998574 2002.1.1.99 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › GHL10 0.53 46.0 3.54e-01 97.9% 88.9%
3728066 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.53 43.0 3.78e-01 86.8% 94.9%
3581387 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.52 39.0 3.78e-01 76.4% 97.5%
3254622 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.52 39.0 3.53e-01 79.9% 97.5%
4169290 2007.2.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.52 37.0 3.56e-01 82.6% 64.2%
3590217 2007.2.5.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese, Rhodanese_C 0.51 37.0 3.27e-01 82.6% 49.3%
4667957 2007.2.5.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase 0.51 37.0 3.69e-01 95.1% 70.3%
4544857 2007.2.5.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese, Rhodanese_C 0.51 37.0 3.30e-01 82.6% 51.7%
4976606 2008.3.1.2 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Eukaryotic RPB5 N-terminal domain › Eukaryotic RPB5 N-terminal domain › Mrr_cat 0.51 35.0 3.78e-01 70.8% 83.3%
4486112 7592.1.1.3 ↗ a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › DUF6293_N 0.51 39.0 4.15e-01 84.7% 94.4%
3332812 207.1.1.133 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_14 0.51 37.0 3.62e-01 77.8% 87.3%
D5 medium residues 299-361
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e9rA02 1.10.8.80 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Magnesium chelatase subunit I, C-Terminal domain 0.68 54.0 4.39e-01 85.7% 93.8%
1n5uA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.66 50.0 4.28e-01 82.5% 88.3%
1mjtB01 3.90.340.10 Alpha Beta › Alpha-Beta Complex › Nitric Oxide Synthase; Chain A, domain 1 › Nitric Oxide Synthase; Chain A, domain 1 0.64 51.0 4.11e-01 88.9% 76.0%
3nufB00 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.62 50.0 4.20e-01 90.5% 66.1%
2o7gA00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.61 41.0 3.75e-01 71.4% 77.3%
4oogC01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.59 48.0 3.52e-01 88.9% 63.6%
3e21A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.58 35.0 4.03e-01 74.6% 97.5%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 32.0 3.25e-01 81.0% 57.4%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.55 43.0 3.95e-01 87.3% 83.7%
2px0A01 1.20.120.1380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar FlhF biosynthesis protein, N domain 0.55 41.0 4.01e-01 82.5% 97.3%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.54 43.0 3.36e-01 90.5% 61.0%
3s95A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 40.0 2.96e-01 85.7% 29.2%
2l2dA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.53 35.0 3.36e-01 71.4% 57.5%
2ekfA01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.53 35.0 3.88e-01 71.4% 93.5%
3a7kB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 41.0 2.81e-01 92.1% 45.7%
1otvA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 42.0 2.89e-01 95.2% 50.0%
5llyA02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.50 42.0 3.13e-01 98.4% 74.1%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3786411 592.1.1.1 ↗ alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.71 60.0 5.09e-01 93.7% 80.6%
4838968 4957.1.1.0 ↗ a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.69 49.0 4.73e-01 77.8% 67.1%
3883598 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.68 52.0 5.08e-01 84.1% 98.6%
3689691 101.1.10.61 ↗ alpha arrays › HTH › HTH › Cyclin-like › Clr5 0.68 55.0 5.03e-01 90.5% 95.3%
3879126 108.1.1.97 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7 0.68 52.0 4.61e-01 82.5% 75.6%
4003844 148.1.3.22 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_5 0.68 49.0 4.05e-01 76.2% 66.4%
3895123 108.1.1.73 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 0.68 51.0 4.60e-01 82.5% 75.6%
3863452 108.1.1.107 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7, EF-hand_8 0.67 51.0 4.56e-01 82.5% 74.4%
3528821 108.1.1.96 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 0.64 49.0 4.35e-01 84.1% 71.6%
4958530 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.63 47.0 4.02e-01 81.0% 84.8%
5076320 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.63 44.0 3.78e-01 73.0% 73.0%
4302906 148.1.3.179 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_BCS1 0.60 42.0 4.32e-01 77.8% 78.3%
3179896 143.1.1.0 ↗ alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain 0.57 38.0 3.89e-01 81.0% 71.7%
3185106 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 43.0 4.07e-01 81.0% 97.3%
3989224 4125.1.1.2 ↗ alpha superhelices › BH3980-like › BH3980-like › BH3980-like › HAAS 0.56 42.0 4.23e-01 84.1% 78.5%
3467958 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.55 39.0 3.87e-01 77.8% 72.9%
4575197 148.1.3.67 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › RNA12 0.55 38.0 3.73e-01 74.6% 78.6%
3711396 148.1.3.179 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_BCS1 0.52 41.0 3.70e-01 85.7% 75.3%
3437969 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 38.0 3.66e-01 90.5% 72.3%