←Back to structures

IMGVR_UViG_3300028048_000061-3300028048-Ga0256405_1000034333

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300028048_000061-3300028048-Ga0256405_1000034333 ↗
Kingdom:: archaea

Quality

52.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 181-342

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF10145.15 best	PhageMin_Tail	51.9	1.40e-13	100.0%	52.7%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4f7nB01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.58	33.0	3.65e-01	84.6%	66.2%
2wa5A01	1.10.418.10	Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain	0.55	32.0	3.88e-01	86.4%	89.2%
1dnyA00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.55	25.0	3.30e-01	72.2%	82.9%
3edvA02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.52	23.0	2.30e-01	80.2%	35.0%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4030882	159.1.2.6 ↗	alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail	0.88	80.0	7.21e-01	100.0%	73.3%
3958350	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.54	27.0	3.43e-01	80.9%	83.5%
3251368	3919.1.1.3 ↗	alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMMD8_HN	0.53	28.0	3.23e-01	94.4%	66.7%
3957923	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.52	26.0	3.24e-01	82.1%	77.8%

D2 medium residues 677-761

PDB

Domain cluster: representative

CATH (72)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4iloA00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.97	93.0	6.43e-01	100.0%	37.7%
4l0rB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.97	74.0	8.01e-01	78.8%	97.3%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.95	91.0	7.14e-01	100.0%	76.7%
2pmsC00	6.10.140.920	Special › Helix non-globular › Helix Hairpins ›	0.94	77.0	6.92e-01	96.5%	66.1%
1nt2B02	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.94	67.0	7.59e-01	82.4%	94.0%
3qo8A01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.94	81.0	7.37e-01	89.4%	75.5%
8ipqB01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.93	63.0	4.16e-01	77.6%	20.3%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.93	71.0	7.76e-01	78.8%	94.4%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.93	72.0	5.45e-01	81.2%	38.9%
2b5uA02	1.10.287.620	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins	0.92	78.0	6.11e-01	88.2%	80.7%
2fcwA00	1.20.81.10	Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain	0.92	75.0	6.92e-01	94.1%	68.9%
3a8pA02	6.10.140.680	Special › Helix non-globular › Helix Hairpins ›	0.92	73.0	6.47e-01	82.4%	63.2%
2rkhA02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.91	66.0	6.98e-01	85.9%	82.9%
4dylA02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.91	78.0	7.47e-01	89.4%	90.4%
6r1nA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.90	81.0	7.48e-01	92.9%	77.7%
2qywA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.90	68.0	6.48e-01	77.6%	73.7%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.90	84.0	5.93e-01	100.0%	43.9%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.90	84.0	6.09e-01	100.0%	56.3%
1t72A01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.89	74.0	6.52e-01	88.2%	63.2%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.89	83.0	6.90e-01	100.0%	61.9%
8fbnB01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.89	72.0	5.12e-01	87.1%	32.4%
1ku9A02	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.89	63.0	7.17e-01	72.9%	100.0%
4ijjB00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.88	77.0	6.46e-01	90.6%	59.2%
4lwsA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.87	68.0	6.42e-01	82.4%	81.0%
4e4eA01	1.10.287.990	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain	0.87	67.0	7.31e-01	81.2%	100.0%
3txsC01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.86	68.0	7.25e-01	83.5%	96.0%
6h9xA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.86	69.0	6.46e-01	84.7%	72.5%
2bdeA03	1.20.58.1160	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.85	67.0	7.07e-01	84.7%	90.9%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.85	75.0	7.33e-01	92.9%	90.0%
2wb7A03	1.20.120.870	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain	0.83	60.0	5.08e-01	85.9%	47.1%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.83	76.0	5.48e-01	100.0%	37.1%
4egwA02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.83	64.0	5.71e-01	82.4%	58.8%
1fewA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	76.0	5.94e-01	100.0%	53.8%
2ieqA00	1.20.5.300	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.83	71.0	7.03e-01	90.6%	87.5%
4ioeA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.83	60.0	5.96e-01	95.3%	73.6%
4iggA01	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.83	62.0	6.85e-01	80.0%	100.0%
2d1lA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.82	75.0	5.31e-01	100.0%	36.5%
6tkvA01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.81	61.0	6.78e-01	83.5%	98.5%
2gd5A00	6.10.140.1230	Special › Helix non-globular › Helix Hairpins ›	0.81	67.0	5.59e-01	91.8%	53.5%
2zdiB00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.81	68.0	6.31e-01	91.8%	90.6%
3ibpA01	1.20.58.850	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.80	65.0	7.03e-01	84.7%	100.0%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.80	60.0	5.73e-01	98.8%	67.7%
4gzrB00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.80	61.0	6.37e-01	82.4%	87.0%
1fs0G02	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.79	70.0	6.88e-01	92.9%	91.0%
4i0xG00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.79	57.0	6.24e-01	76.5%	100.0%
2dq0A01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.78	66.0	6.16e-01	97.6%	74.8%
4biuE01	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.77	70.0	6.71e-01	100.0%	100.0%
4w4kA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.77	62.0	6.32e-01	85.9%	90.2%
3ggyA00	1.20.1260.60	Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1	0.77	62.0	4.80e-01	88.2%	40.9%
4b6xA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.76	54.0	5.87e-01	80.0%	92.8%
3r84B00	6.10.280.160	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22	0.75	58.0	5.94e-01	82.4%	86.3%
4dciA00	6.10.140.1110	Special › Helix non-globular › Helix Hairpins ›	0.75	62.0	5.10e-01	95.3%	51.0%
6v9zA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.75	65.0	4.26e-01	92.9%	26.5%
3agtA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.74	51.0	4.37e-01	71.8%	45.1%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.74	57.0	5.91e-01	82.4%	96.2%
1b3qA01	1.10.287.560	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain	0.74	49.0	5.48e-01	70.6%	93.5%
2ke4A00	6.10.140.470	Special › Helix non-globular › Helix Hairpins ›	0.74	58.0	5.60e-01	87.1%	74.5%
1sziA02	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.73	60.0	5.15e-01	90.6%	56.9%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.73	59.0	5.60e-01	89.4%	75.5%
1l8dA00	1.10.287.510	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.72	65.0	6.10e-01	100.0%	82.5%
3rkgA02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.72	56.0	4.56e-01	84.7%	50.0%
1sg2A00	3.30.910.20	Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain	0.71	51.0	4.31e-01	75.3%	58.9%
4h63H01	1.20.58.1710	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	55.0	5.85e-01	83.5%	100.0%
7sgrA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.71	61.0	4.19e-01	97.6%	26.8%
2rdcA00	1.10.287.800	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242	0.70	53.0	4.66e-01	85.9%	52.6%
3zdqA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.70	59.0	3.92e-01	91.8%	24.0%
6ynwH01	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.68	54.0	5.75e-01	89.4%	98.6%
4mrsA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.67	58.0	3.89e-01	97.6%	25.1%
1i6zA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.66	58.0	5.00e-01	97.6%	69.6%
4v1gA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.66	56.0	5.60e-01	92.9%	94.1%
8e9gK01	1.10.287.3510	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.66	46.0	4.50e-01	71.8%	67.0%
3hwcA03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.64	56.0	4.24e-01	98.8%	81.4%

ECOD (76)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3657123	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.98	82.0	7.80e-01	97.6%	76.8%
4338795	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.97	82.0	6.22e-01	87.1%	47.6%
4028066	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.97	83.0	6.43e-01	97.6%	46.1%
5064482	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.96	92.0	7.11e-01	100.0%	51.5%
3486385	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.96	79.0	7.28e-01	85.9%	69.5%
5024408	3755.3.1.637 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121	0.96	92.0	6.82e-01	100.0%	49.7%
4007316	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.95	89.0	7.03e-01	97.6%	67.1%
3699465	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.95	91.0	7.27e-01	100.0%	66.0%
3934585	3755.3.1.465 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A	0.95	91.0	7.24e-01	100.0%	59.3%
3268736	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.95	91.0	5.38e-01	100.0%	16.8%
5067713	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.95	82.0	7.33e-01	91.8%	69.1%
3503444	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.94	75.0	7.35e-01	82.4%	77.8%
4957994	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.94	90.0	5.80e-01	100.0%	55.3%
3719459	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.94	89.0	6.67e-01	100.0%	62.7%
315449	192.8.1.2 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap	0.94	73.0	7.78e-01	81.2%	90.8%
3448091	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.94	78.0	6.87e-01	87.1%	64.0%
4018440	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.93	86.0	8.18e-01	95.3%	88.4%
3853063	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.93	77.0	6.71e-01	87.1%	60.8%
5025381	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.93	88.0	5.69e-01	100.0%	54.5%
3832457	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.92	88.0	6.11e-01	100.0%	59.6%
3393794	3922.1.1.211 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C	0.92	80.0	6.70e-01	100.0%	57.8%
5002089	2004.1.1.144 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2	0.92	76.0	4.92e-01	85.9%	24.8%
3273862	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.92	82.0	7.83e-01	92.9%	85.3%
4947573	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.92	86.0	5.68e-01	100.0%	35.1%
3745853	603.2.1.1 ↗	alpha bundles › STAT-like › STAT › STAT › STAT_alpha	0.92	87.0	6.50e-01	100.0%	50.3%
3594486	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.92	84.0	7.33e-01	97.6%	68.3%
4809272	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.91	80.0	6.95e-01	100.0%	64.5%
5054469	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.91	79.0	7.27e-01	91.8%	73.3%
4784164	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.91	70.0	7.71e-01	80.0%	97.1%
5079778	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.91	87.0	5.24e-01	100.0%	18.7%
4784166	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.91	70.0	7.64e-01	82.4%	97.1%
4488200	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.90	74.0	6.67e-01	85.9%	66.1%
3781506	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.90	85.0	6.76e-01	100.0%	59.4%
3491418	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.90	73.0	7.76e-01	84.7%	96.0%
4235305	633.7.1.14 ↗	alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like › MG280	0.90	71.0	6.69e-01	82.4%	70.0%
3239791	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.90	82.0	6.22e-01	97.6%	45.6%
3170937	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.90	84.0	5.66e-01	100.0%	38.5%
3902100	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.90	76.0	7.62e-01	89.4%	89.4%
3291561	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.89	70.0	7.48e-01	94.1%	93.3%
3929349	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	83.0	6.07e-01	98.8%	84.9%
3170139	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	81.0	6.41e-01	95.3%	56.1%
4982498	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.89	84.0	4.89e-01	100.0%	22.0%
5059556	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	84.0	6.43e-01	100.0%	60.6%
3556027	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	75.0	7.52e-01	89.4%	89.4%
3494796	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.89	83.0	5.63e-01	100.0%	32.2%
4798159	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.89	70.0	7.38e-01	84.7%	92.1%
3855461	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.88	74.0	7.49e-01	89.4%	89.4%
None	—		0.88	83.0	5.58e-01	100.0%	31.0%
4683070	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.88	83.0	6.84e-01	100.0%	67.9%
3487862	212.1.1.0 ↗	a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like	0.88	78.0	5.47e-01	97.6%	33.3%
4969096	3926.1.1.0 ↗	alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D	0.88	82.0	5.71e-01	100.0%	34.0%
4542972	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.88	83.0	6.03e-01	100.0%	41.5%
3268739	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.87	77.0	7.27e-01	95.3%	79.0%
3029523	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.87	80.0	5.43e-01	98.8%	30.3%
3232850	3684.1.1.48 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BBS2_hp	0.87	78.0	7.49e-01	94.1%	89.5%
3186867	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.87	81.0	6.30e-01	98.8%	77.0%
3271624	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.87	82.0	4.99e-01	98.8%	32.9%
3744077	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.86	80.0	5.56e-01	100.0%	34.1%
3779488	3755.4.1.69 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF28341	0.86	80.0	5.93e-01	100.0%	58.5%
2323907	212.1.1.24 ↗	a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5	0.85	74.0	5.32e-01	97.6%	35.2%
3824276	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.84	68.0	5.11e-01	83.5%	96.1%
4031283	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.84	77.0	6.28e-01	100.0%	66.7%
3388215	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.84	76.0	6.04e-01	98.8%	50.9%
4951266	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.83	77.0	4.84e-01	100.0%	29.5%
3318681	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.83	76.0	5.14e-01	98.8%	29.8%
3877003	632.22.1.95 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF28341	0.83	75.0	5.73e-01	100.0%	45.3%
4951835	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.82	76.0	6.58e-01	100.0%	73.6%
3215082	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.81	74.0	6.29e-01	100.0%	65.9%
3484742	3922.1.1.197 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp	0.80	66.0	6.67e-01	89.4%	89.4%
3595002	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.80	61.0	5.75e-01	81.2%	68.0%
5031890	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.80	71.0	5.12e-01	100.0%	35.1%
4030237	192.7.1.0 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm	0.80	58.0	5.50e-01	80.0%	65.0%
3167298	3711.1.1.0 ↗	alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein	0.78	69.0	6.43e-01	100.0%	78.1%
3239971	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.77	70.0	5.09e-01	100.0%	37.4%
4029165	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.74	69.0	4.30e-01	100.0%	52.9%
4936792	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.73	64.0	5.04e-01	100.0%	45.4%

D3 medium residues 762-845

PDB

Domain cluster: rep: IMGVR_UViG_3300036943_000163-3300036943-Ga0377187_010073_849_1439__D24-110

CATH (87)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4dylA02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.96	93.0	8.84e-01	100.0%	92.6%
1fewA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.96	92.0	6.96e-01	100.0%	56.6%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.95	91.0	6.45e-01	100.0%	52.6%
4b6xA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.94	75.0	8.26e-01	83.3%	100.0%
3u0cA00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.94	88.0	6.97e-01	100.0%	54.3%
3tulB00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.94	89.0	7.40e-01	100.0%	65.4%
1fpoC02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.93	68.0	6.61e-01	77.4%	69.2%
1y1uA01	1.20.1050.20	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain	0.93	88.0	6.49e-01	100.0%	59.5%
2oduA02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.93	80.0	7.36e-01	94.0%	72.4%
6gy8A01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.93	89.0	5.67e-01	100.0%	50.0%
1s3qG00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.93	72.0	5.54e-01	81.0%	41.1%
6h9xA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.93	83.0	7.63e-01	98.8%	76.5%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.92	87.0	6.06e-01	98.8%	58.5%
1ku9A02	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.92	67.0	7.70e-01	82.1%	100.0%
3uo2B02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.91	62.0	6.27e-01	75.0%	70.2%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.91	85.0	6.71e-01	100.0%	81.8%
3k29A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.90	85.0	6.65e-01	100.0%	70.2%
1nfvA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.90	71.0	5.46e-01	82.1%	40.8%
2fcwA00	1.20.81.10	Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain	0.89	83.0	7.56e-01	98.8%	78.3%
1nt2B02	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.89	68.0	7.55e-01	79.8%	100.0%
3hiuD00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.89	70.0	5.59e-01	82.1%	75.0%
7sgrA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.89	83.0	5.45e-01	100.0%	28.1%
4i1mB01	1.20.120.1700	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.88	65.0	5.46e-01	78.6%	49.6%
2gd5A00	6.10.140.1230	Special › Helix non-globular › Helix Hairpins ›	0.87	81.0	6.68e-01	100.0%	59.9%
6q45G01	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.87	81.0	6.61e-01	100.0%	65.8%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.87	81.0	6.70e-01	100.0%	65.5%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.86	80.0	5.64e-01	100.0%	45.6%
6v9zA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.86	79.0	5.17e-01	98.8%	25.8%
6r1nA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.86	75.0	6.97e-01	92.9%	82.5%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.86	79.0	7.37e-01	100.0%	88.2%
1sziA02	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.85	72.0	6.00e-01	90.5%	54.7%
4q4hA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.85	78.0	5.16e-01	100.0%	27.4%
3nkzA00	1.20.58.380	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit.	0.85	58.0	5.50e-01	73.8%	60.8%
2wb7A03	1.20.120.870	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain	0.85	62.0	5.19e-01	79.8%	47.1%
3b2eF00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.85	60.0	6.96e-01	78.6%	100.0%
3agtA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.85	58.0	4.86e-01	70.2%	85.7%
4h63H01	1.20.58.1710	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.84	66.0	7.04e-01	82.1%	100.0%
3lssA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.84	74.0	6.71e-01	100.0%	72.3%
4lwsA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.84	77.0	7.28e-01	100.0%	88.0%
6tkvA01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.84	64.0	7.06e-01	95.2%	98.5%
3r6nA02	1.20.58.1060	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	74.0	5.97e-01	96.4%	52.3%
1b3qA01	1.10.287.560	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain	0.83	56.0	6.38e-01	71.4%	93.5%
3nrxA00	1.20.58.1520	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	69.0	5.98e-01	94.0%	60.2%
3okqA00	1.20.58.1540	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain	0.82	75.0	6.55e-01	100.0%	67.2%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.82	69.0	6.48e-01	89.3%	78.8%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.82	74.0	4.98e-01	100.0%	27.5%
6bl6B01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.82	74.0	4.93e-01	98.8%	26.6%
3pltA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.82	76.0	5.49e-01	98.8%	39.3%
4i0xG00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.82	59.0	6.47e-01	75.0%	100.0%
3ggyA00	1.20.1260.60	Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1	0.82	72.0	5.47e-01	95.2%	43.0%
1fs0G02	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.82	74.0	7.27e-01	100.0%	89.9%
1j5wA02	1.20.58.180	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2	0.81	53.0	5.55e-01	83.3%	72.7%
4lwsB00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.81	70.0	6.91e-01	95.2%	90.9%
1x04A00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.81	74.0	5.50e-01	100.0%	45.5%
4iloA00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.81	72.0	5.19e-01	100.0%	37.3%
4ciuA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.80	68.0	5.07e-01	89.3%	39.6%
6tqfA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.80	72.0	4.61e-01	100.0%	21.5%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.80	63.0	6.73e-01	100.0%	100.0%
3zbhA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.80	70.0	6.92e-01	96.4%	93.3%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.80	65.0	5.09e-01	90.5%	42.3%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.79	71.0	6.92e-01	100.0%	90.0%
2xubA05	6.10.140.1450	Special › Helix non-globular › Helix Hairpins ›	0.79	73.0	6.96e-01	100.0%	96.9%
8fbnB01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.79	65.0	4.72e-01	91.7%	33.8%
4ijjB00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.79	66.0	5.69e-01	91.7%	60.8%
1fioA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.78	73.0	5.48e-01	100.0%	51.6%
1m5iA00	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.78	71.0	6.59e-01	100.0%	82.9%
2ke4A00	6.10.140.470	Special › Helix non-globular › Helix Hairpins ›	0.78	72.0	6.81e-01	100.0%	85.7%
4gzrB00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.78	65.0	6.75e-01	100.0%	97.4%
1t72A01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.77	66.0	5.88e-01	94.0%	66.7%
2bdeA03	1.20.58.1160	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.77	61.0	6.32e-01	86.9%	92.2%
4v1gA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.77	60.0	6.06e-01	83.3%	94.1%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.77	64.0	6.62e-01	89.3%	100.0%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.77	68.0	5.09e-01	100.0%	39.4%
7wivA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.76	68.0	4.55e-01	97.6%	26.7%
1l8dA00	1.10.287.510	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.76	70.0	6.53e-01	100.0%	81.6%
5dn6J00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.76	60.0	6.28e-01	84.5%	100.0%
1i6zA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.75	63.0	5.43e-01	95.2%	57.8%
3r84B00	6.10.280.160	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22	0.75	66.0	6.73e-01	95.2%	98.8%
2qe7G01	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.75	67.0	6.39e-01	100.0%	96.9%
4dciA00	6.10.140.1110	Special › Helix non-globular › Helix Hairpins ›	0.75	68.0	5.62e-01	100.0%	60.5%
4ioeA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.75	64.0	6.41e-01	97.6%	95.4%
2ieqA00	1.20.5.300	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.74	67.0	6.65e-01	100.0%	100.0%
2e9xA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.74	64.0	5.53e-01	95.2%	62.5%
4cqiA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.73	66.0	6.11e-01	100.0%	78.5%
4w4kA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.69	60.0	6.06e-01	98.8%	100.0%
6ynwH01	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.67	54.0	5.72e-01	91.7%	100.0%
2x2vA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.67	50.0	5.43e-01	94.0%	100.0%

ECOD (90)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3232850	3684.1.1.48 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BBS2_hp	0.97	93.0	8.89e-01	100.0%	88.4%
4951835	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.97	93.0	7.92e-01	100.0%	67.2%
3484742	3922.1.1.197 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp	0.97	92.0	9.17e-01	98.8%	97.6%
3595707	5086.1.1.118 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp	0.96	92.0	7.74e-01	100.0%	64.6%
3781506	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.96	92.0	7.26e-01	100.0%	54.2%
4345017	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.96	92.0	5.29e-01	100.0%	20.2%
3831567	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.96	92.0	7.01e-01	100.0%	65.9%
3521820	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.96	92.0	6.36e-01	100.0%	36.2%
3710275	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.96	92.0	6.31e-01	100.0%	35.4%
4002750	5086.1.1.118 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp	0.96	92.0	7.67e-01	100.0%	64.6%
3483188	605.2.1.7 ↗	alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › BBS2_hp	0.96	90.0	9.04e-01	98.8%	98.8%
None	—		0.95	91.0	7.60e-01	100.0%	64.6%
3929349	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.95	90.0	6.50e-01	100.0%	41.5%
5025381	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.95	90.0	5.77e-01	100.0%	50.9%
4977923	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.94	90.0	7.01e-01	100.0%	56.9%
3713930	3939.1.1.0 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain	0.94	90.0	5.54e-01	100.0%	21.0%
5079778	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.94	90.0	5.41e-01	100.0%	20.0%
4514051	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.94	88.0	7.71e-01	97.6%	71.3%
5047072	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.94	90.0	6.98e-01	100.0%	52.5%
3611804	5086.1.1.102 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp	0.94	89.0	7.51e-01	100.0%	64.6%
4007316	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.94	89.0	7.03e-01	100.0%	72.3%
4338795	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.94	90.0	6.83e-01	100.0%	49.4%
3269590	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.94	87.0	7.65e-01	97.6%	71.3%
3699465	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.93	89.0	7.08e-01	100.0%	70.0%
5018814	3755.3.1.633 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PspA_IM30	0.93	88.0	6.49e-01	100.0%	43.1%
3626769	192.5.1.14 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA	0.93	87.0	8.48e-01	97.6%	91.1%
3529707	4.1.1.453 ↗	beta barrels › SH3 › SH3 › SH3 › HR1_TOCA	0.93	89.0	8.46e-01	100.0%	88.4%
3594486	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.93	84.0	7.31e-01	95.2%	74.2%
4676629	3755.3.1.290 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPI_helical	0.93	88.0	6.15e-01	100.0%	45.7%
4001188	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.93	87.0	5.33e-01	100.0%	57.2%
3925617	192.5.1.14 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA	0.92	82.0	8.22e-01	92.9%	91.8%
3499411	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.92	88.0	5.19e-01	100.0%	17.2%
3613659	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.92	87.0	6.78e-01	100.0%	51.2%
3535225	3939.1.1.369 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › PF28341	0.92	87.0	6.32e-01	100.0%	41.0%
3567670	192.5.1.14 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA	0.92	86.0	8.36e-01	97.6%	91.1%
3960197	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.92	87.0	6.21e-01	100.0%	58.6%
5024408	3755.3.1.637 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121	0.92	87.0	6.49e-01	100.0%	45.4%
3170139	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.92	87.0	6.87e-01	100.0%	54.2%
None	—		0.92	86.0	6.09e-01	100.0%	37.8%
3256420	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.92	87.0	5.84e-01	100.0%	31.5%
4882756	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.91	86.0	6.96e-01	100.0%	57.1%
3877882	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.91	86.0	5.95e-01	100.0%	34.3%
3213526	192.5.1.14 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA	0.91	85.0	7.74e-01	97.6%	78.1%
4477580	5086.1.1.118 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp	0.91	78.0	7.81e-01	90.5%	90.6%
3877003	632.22.1.95 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF28341	0.91	86.0	6.37e-01	100.0%	44.2%
5032400	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.91	85.0	6.62e-01	100.0%	50.9%
5031890	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.91	85.0	5.90e-01	100.0%	34.3%
4426045	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.90	80.0	6.49e-01	95.2%	54.5%
3239791	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.90	78.0	5.89e-01	100.0%	42.8%
4969096	3926.1.1.0 ↗	alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D	0.90	83.0	5.66e-01	96.4%	57.6%
3628737	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.90	84.0	5.88e-01	100.0%	41.7%
4985494	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.90	85.0	5.11e-01	100.0%	17.7%
4944766	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.89	84.0	6.12e-01	100.0%	41.0%
3186867	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	80.0	6.20e-01	94.0%	76.4%
4974450	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.89	82.0	6.28e-01	100.0%	47.4%
3719459	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	83.0	6.23e-01	100.0%	45.4%
4623646	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.89	84.0	5.18e-01	100.0%	28.9%
4542972	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.89	82.0	6.03e-01	100.0%	44.9%
3908626	3755.3.1.483 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30493	0.88	83.0	5.70e-01	100.0%	55.3%
5002102	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.88	83.0	6.39e-01	100.0%	49.4%
3682641	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.88	81.0	6.24e-01	100.0%	48.0%
3600184	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.88	81.0	6.73e-01	100.0%	60.7%
4947573	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.87	81.0	5.36e-01	100.0%	27.5%
3772767	5086.1.1.87 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING	0.87	81.0	6.98e-01	100.0%	68.0%
3895215	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.87	81.0	5.86e-01	100.0%	39.5%
3553813	3291.1.1.82 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING	0.87	80.0	6.94e-01	100.0%	68.0%
3892960	3291.1.1.86 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PL48	0.87	80.0	6.66e-01	100.0%	60.7%
4028066	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.86	80.0	6.26e-01	100.0%	50.9%
3187178	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.86	80.0	5.97e-01	100.0%	43.1%
5047335	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.86	79.0	6.52e-01	100.0%	57.9%
4386662	3291.1.1.158 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Seryl_tRNA_N	0.86	79.0	7.01e-01	98.8%	73.9%
4030412	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.86	79.0	6.11e-01	100.0%	48.0%
3239667	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.86	79.0	4.57e-01	100.0%	11.9%
3824276	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.85	79.0	6.01e-01	100.0%	46.7%
3268736	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.84	77.0	4.66e-01	100.0%	30.9%
3412574	3291.1.1.82 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING	0.83	77.0	6.54e-01	100.0%	65.4%
3489648	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.83	76.0	6.27e-01	100.0%	60.0%
4862474	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.83	75.0	6.27e-01	100.0%	59.2%
3607135	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.82	76.0	6.38e-01	100.0%	63.0%
3393794	3922.1.1.211 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C	0.81	76.0	6.36e-01	100.0%	77.8%
5054861	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.81	74.0	4.56e-01	100.0%	28.6%
3608116	5086.1.1.177 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9	0.80	72.0	6.00e-01	100.0%	57.9%
3746558	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.79	72.0	5.31e-01	100.0%	43.3%
3949790	150.5.1.1 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100	0.79	71.0	6.73e-01	100.0%	85.0%
3239971	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.79	72.0	5.18e-01	100.0%	46.1%
3630220	3755.3.1.103 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Golgin_A5	0.78	70.0	5.30e-01	98.8%	76.9%
3271624	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.78	69.0	4.36e-01	100.0%	19.3%
3903422	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.77	69.0	6.15e-01	100.0%	72.5%
3607087	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.77	69.0	5.77e-01	100.0%	59.3%
3589720	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.68	57.0	4.86e-01	95.2%	55.9%

D4 medium residues 846-922

PDB

Domain cluster: representative

CATH (84)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2r9iA00	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.95	76.0	7.96e-01	88.3%	90.1%
1lrzA03	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.94	73.0	8.08e-01	89.6%	100.0%
3a8pA02	6.10.140.680	Special › Helix non-globular › Helix Hairpins ›	0.94	85.0	7.24e-01	100.0%	64.0%
4l0rB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.93	83.0	8.57e-01	98.7%	98.6%
4lwsA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.93	83.0	7.45e-01	93.5%	89.0%
1cxzB00	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.92	80.0	7.67e-01	94.8%	81.4%
3tklB01	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.91	70.0	7.78e-01	84.4%	98.4%
3mq1A01	1.20.58.970	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.91	79.0	7.35e-01	98.7%	76.1%
2qywA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.91	78.0	7.23e-01	96.1%	73.7%
1skvA00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.90	72.0	7.87e-01	87.0%	100.0%
3u0cA00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.89	81.0	6.29e-01	98.7%	49.0%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.89	82.0	5.77e-01	98.7%	36.2%
1x8zB00	1.20.140.40	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein	0.89	65.0	5.14e-01	100.0%	40.1%
2dw4A03	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.89	72.0	6.49e-01	98.7%	65.3%
7sgrA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.88	82.0	5.26e-01	98.7%	24.8%
6v9zA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.88	82.0	5.21e-01	98.7%	23.4%
1tjlA00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.88	79.0	6.23e-01	94.8%	59.3%
1x4tA01	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.88	64.0	7.23e-01	79.2%	100.0%
3fxdB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.88	63.0	7.21e-01	87.0%	98.3%
2yevC00	6.10.280.110	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.87	67.0	7.39e-01	93.5%	98.4%
2cazC00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.87	67.0	7.23e-01	85.7%	96.9%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.87	79.0	7.11e-01	98.7%	73.5%
2hh7A00	1.20.58.1000	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer	0.86	70.0	6.80e-01	85.7%	78.8%
1rq0A01	6.10.140.160	Special › Helix non-globular › Helix Hairpins ›	0.86	70.0	6.85e-01	88.3%	79.5%
4aifA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.86	59.0	4.64e-01	76.6%	37.5%
2vxxA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.86	72.0	5.37e-01	89.6%	39.5%
1qsdA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.86	78.0	7.02e-01	98.7%	76.5%
8fbnB01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.86	75.0	5.23e-01	93.5%	52.7%
1avoB00	1.20.120.180	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain	0.86	76.0	6.13e-01	98.7%	52.9%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.85	78.0	5.48e-01	98.7%	36.3%
3hr0B01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.85	77.0	7.67e-01	98.7%	97.5%
3zgxA02	6.10.140.1720	Special › Helix non-globular › Helix Hairpins ›	0.85	77.0	7.28e-01	98.7%	86.8%
1zpyA00	6.10.140.1960	Special › Helix non-globular › Helix Hairpins ›	0.84	70.0	6.54e-01	92.2%	73.6%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.84	78.0	7.36e-01	100.0%	95.6%
4adzA00	1.20.58.1000	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer	0.84	69.0	6.51e-01	87.0%	74.4%
2rkhA02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.83	64.0	6.45e-01	98.7%	80.3%
2p7vA00	1.20.120.1370	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4	0.83	74.0	5.80e-01	96.1%	49.0%
3vbbE01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.83	77.0	6.54e-01	100.0%	84.9%
4fzsA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.83	74.0	5.35e-01	98.7%	36.4%
7wivA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.83	75.0	4.90e-01	98.7%	25.1%
1sg2A00	3.30.910.20	Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain	0.82	69.0	5.59e-01	96.1%	49.6%
2q0oC00	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.81	71.0	6.82e-01	94.8%	86.0%
4q4hA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.81	73.0	4.74e-01	98.7%	24.2%
2q12A00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.81	71.0	4.99e-01	98.7%	32.2%
3lnnB03	1.10.287.470	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.81	64.0	6.79e-01	85.7%	100.0%
6gy8A01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.80	72.0	4.65e-01	98.7%	23.2%
4iggA01	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.80	63.0	6.73e-01	97.4%	97.0%
4h63K00	1.10.287.3490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	67.0	6.22e-01	97.4%	72.4%
3uumA00	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.80	70.0	6.00e-01	97.4%	71.3%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	70.0	4.95e-01	98.7%	32.9%
4ceiA03	6.10.250.2380	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.79	62.0	5.43e-01	83.1%	100.0%
1egdA03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.79	68.0	5.49e-01	93.5%	51.1%
1rx0A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.79	71.0	5.56e-01	100.0%	49.0%
2o8pA00	1.20.190.20	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain	0.79	73.0	5.11e-01	100.0%	48.9%
2p4vA01	1.10.287.180	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain	0.78	65.0	6.54e-01	88.3%	90.8%
2uxwA01	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.78	70.0	5.23e-01	100.0%	40.9%
1sj8A02	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.78	61.0	5.19e-01	83.1%	54.9%
4mrsA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.78	70.0	4.49e-01	98.7%	22.2%
3pltA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.78	69.0	4.95e-01	100.0%	35.0%
1uruA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.78	69.0	4.97e-01	97.4%	69.9%
4iloA00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.78	68.0	4.85e-01	100.0%	33.9%
3k29A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.77	68.0	5.35e-01	98.7%	49.1%
3fppA03	6.10.140.1990	Special › Helix non-globular › Helix Hairpins ›	0.77	68.0	6.56e-01	98.7%	87.5%
1vf7A03	1.10.287.470	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.77	57.0	6.28e-01	88.3%	100.0%
4dciA00	6.10.140.1110	Special › Helix non-globular › Helix Hairpins ›	0.77	69.0	5.59e-01	100.0%	61.2%
1h7cA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.77	68.0	6.20e-01	98.7%	75.7%
4l8jA04	1.10.287.470	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.76	55.0	6.13e-01	92.2%	98.3%
3icxA01	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.76	65.0	6.65e-01	98.7%	100.0%
4y9jA01	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.76	65.0	5.26e-01	96.1%	49.7%
3qo8A01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.75	66.0	5.96e-01	98.7%	71.7%
2lw1A00	1.10.287.380	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain	0.75	66.0	6.41e-01	96.1%	88.2%
2ficB00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.75	66.0	4.87e-01	100.0%	37.8%
4h63H01	1.20.58.1710	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.75	62.0	6.45e-01	90.9%	98.6%
4mtxD00	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.75	58.0	5.49e-01	85.7%	72.6%
2pg0A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.74	66.0	5.32e-01	100.0%	51.7%
4akgA11	1.20.920.20	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.74	64.0	4.39e-01	98.7%	27.2%
2gtsA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.74	64.0	6.45e-01	98.7%	97.4%
3vkgB06	1.20.920.20	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.74	65.0	4.58e-01	100.0%	39.6%
3smtA02	3.90.1420.10	Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain	0.73	64.0	4.90e-01	93.5%	60.4%
3lbxB01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.73	61.0	5.55e-01	97.4%	68.2%
4ke2A00	6.10.140.1860	Special › Helix non-globular › Helix Hairpins ›	0.68	58.0	4.37e-01	96.1%	98.5%
2uuiA00	1.20.120.550	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain	0.67	50.0	4.03e-01	80.5%	44.5%
1kf6C00	1.20.1300.10	Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit	0.65	53.0	4.47e-01	90.9%	54.6%
1c17M00	1.20.120.220	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A	0.61	52.0	4.36e-01	98.7%	100.0%

ECOD (82)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3872955	109.4.1.2380 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_10, TPR_12, TPR_MalT	0.94	85.0	4.99e-01	98.7%	14.9%
3935140	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.93	87.0	6.39e-01	98.7%	81.1%
3249317	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.93	87.0	6.59e-01	98.7%	60.6%
3654714	5086.1.1.89 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF21A_4th	0.93	87.0	6.21e-01	98.7%	39.0%
4446057	192.8.1.345 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF30463	0.93	87.0	6.07e-01	98.7%	36.2%
4428739	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.92	86.0	5.71e-01	98.7%	66.0%
3609516	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.92	88.0	6.46e-01	100.0%	45.7%
3073109	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.92	84.0	8.64e-01	96.1%	100.0%
5009131	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.92	80.0	6.01e-01	98.7%	42.4%
3782889	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.92	85.0	5.93e-01	97.4%	53.0%
3729994	3755.3.1.284 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Utp11	0.92	78.0	6.40e-01	98.7%	53.1%
5040665	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.92	86.0	4.96e-01	98.7%	29.5%
3498458	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.92	86.0	6.45e-01	98.7%	46.7%
3714442	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.92	86.0	5.81e-01	100.0%	51.2%
3805780	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.91	86.0	5.91e-01	100.0%	50.0%
3705783	192.5.1.0 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat	0.91	84.0	7.88e-01	96.1%	82.2%
3766572	4177.1.1.112 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › bMERB_dom	0.91	87.0	6.46e-01	100.0%	46.7%
3390311	604.7.1.0 ↗	alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A	0.91	86.0	7.49e-01	100.0%	70.9%
5008718	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.91	85.0	5.05e-01	98.7%	18.0%
3718408	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.91	83.0	7.21e-01	96.1%	67.3%
3605251	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.91	86.0	5.99e-01	100.0%	95.8%
3605626	192.12.1.0 ↗	alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM	0.91	83.0	7.31e-01	96.1%	70.5%
3465330	4177.1.1.11 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632	0.90	84.0	6.26e-01	98.7%	54.1%
3413926	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.90	84.0	5.55e-01	98.7%	29.1%
5026581	1203.1.2.0 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2	0.90	83.0	6.36e-01	98.7%	48.1%
4984240	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.89	84.0	4.85e-01	98.7%	13.5%
3671258	632.22.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats	0.89	82.0	6.76e-01	98.7%	96.9%
3976632	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.89	83.0	6.46e-01	98.7%	51.3%
3657504	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.89	83.0	6.69e-01	98.7%	62.2%
4998877	150.1.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin	0.89	78.0	6.00e-01	93.5%	45.8%
4646268	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.89	76.0	8.01e-01	94.8%	100.0%
3896686	192.8.1.36 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain	0.89	79.0	7.17e-01	94.8%	76.0%
3660998	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.89	83.0	4.99e-01	100.0%	34.8%
3935107	192.7.1.0 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm	0.88	82.0	7.12e-01	98.7%	69.1%
4543996	3600.1.1.1 ↗	alpha bundles › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › YlqD	0.88	82.0	7.22e-01	98.7%	71.4%
3481122	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.88	74.0	6.74e-01	93.5%	69.0%
3609803	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.88	80.0	5.49e-01	98.7%	32.1%
3831005	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.87	80.0	4.95e-01	98.7%	19.5%
4024537	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.87	82.0	5.85e-01	100.0%	40.0%
4061849	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.87	82.0	7.11e-01	100.0%	71.8%
3982421	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.87	75.0	7.64e-01	97.4%	94.7%
3753969	622.4.1.0 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related	0.86	72.0	6.51e-01	88.3%	72.0%
3682989	5086.1.1.96 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF632	0.86	80.0	6.37e-01	100.0%	80.0%
3564754	604.1.1.96 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31	0.86	79.0	6.48e-01	100.0%	57.0%
3402327	3755.3.1.324 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725	0.86	79.0	5.97e-01	98.7%	45.3%
3389783	5030.1.1.0 ↗	extended segments › Photosystem II reaction center protein L, PsbL › Photosystem II reaction center protein L, PsbL › Photosystem II reaction center protein L, PsbL	0.86	76.0	6.82e-01	98.7%	70.5%
5041482	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.86	78.0	7.23e-01	98.7%	88.4%
4665988	192.7.1.0 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm	0.86	75.0	6.65e-01	93.5%	75.2%
3879173	4177.1.1.4 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD	0.85	78.0	5.32e-01	100.0%	31.8%
4581983	5086.1.1.13 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB	0.85	74.0	6.01e-01	94.8%	79.3%
4167714	109.4.1.198 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12	0.85	79.0	5.25e-01	100.0%	41.9%
3855880	622.4.1.19 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › CD20	0.84	76.0	6.74e-01	96.1%	73.3%
None	—		0.84	76.0	5.17e-01	98.7%	29.8%
3991276	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.84	76.0	5.08e-01	98.7%	28.0%
3377936	3922.1.1.173 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493	0.84	76.0	7.34e-01	98.7%	89.4%
3814372	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.83	74.0	6.70e-01	100.0%	80.0%
3447256	603.1.1.17 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE	0.82	75.0	5.18e-01	100.0%	65.3%
3445974	1075.4.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane	0.82	74.0	4.88e-01	100.0%	26.6%
3813837	622.4.1.0 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related	0.82	68.0	6.95e-01	89.6%	92.0%
1097227	3755.1.1.2 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO-like	0.81	73.0	5.67e-01	98.7%	79.6%
3928077	3636.1.1.0 ↗	a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain	0.81	75.0	5.97e-01	100.0%	60.0%
4429259	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.81	71.0	5.73e-01	96.1%	51.7%
4295915	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.81	72.0	6.06e-01	100.0%	97.7%
3186506	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.81	72.0	4.56e-01	100.0%	25.3%
3906467	1008.1.1.106 ↗	alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › CSN5_C	0.80	72.0	6.85e-01	98.7%	86.7%
4541195	3755.3.1.470 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB	0.80	71.0	5.98e-01	98.7%	59.2%
3575793	632.8.1.2 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C	0.80	71.0	6.29e-01	98.7%	69.1%
3989648	1203.1.2.17 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ABC_membrane	0.80	71.0	5.19e-01	98.7%	38.0%
3755476	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.79	70.0	5.36e-01	98.7%	44.0%
3461932	3922.1.1.189 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF630	0.79	72.0	6.68e-01	100.0%	83.2%
5029677	1075.4.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane	0.79	71.0	4.62e-01	100.0%	23.6%
4026286	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.78	71.0	5.84e-01	100.0%	82.2%
4102446	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.78	62.0	4.53e-01	98.7%	32.2%
3387205	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.78	71.0	6.78e-01	100.0%	86.7%
3915506	3922.1.1.274 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DMPK_coil	0.78	68.0	4.76e-01	98.7%	31.4%
3207569	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.76	66.0	4.92e-01	98.7%	39.0%
3613914	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.76	65.0	6.62e-01	98.7%	100.0%
4806319	3755.1.1.2 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO-like	0.76	67.0	6.54e-01	98.7%	92.8%
3245542	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.75	68.0	5.85e-01	100.0%	65.0%
3513582	192.8.1.36 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain	0.75	64.0	5.73e-01	97.4%	67.3%
3615972	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.73	63.0	4.84e-01	98.7%	72.4%
4875585	1075.4.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane	0.72	63.0	4.12e-01	100.0%	63.3%

D5 medium residues 1133-1223

PDB

Domain cluster: representative

CATH (73)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3dplC03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.84	49.0	5.11e-01	81.3%	63.9%
8ek4A01	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.75	65.0	5.66e-01	100.0%	63.2%
3ukmA01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.74	61.0	4.42e-01	90.1%	39.7%
1qsdA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.74	54.0	5.20e-01	100.0%	67.6%
4okvE00	6.10.140.1890	Special › Helix non-globular › Helix Hairpins ›	0.73	51.0	5.81e-01	93.4%	100.0%
2m6uA00	1.20.81.20	Mainly Alpha › Up-down Bundle › Receptor-associated Protein ›	0.73	46.0	4.88e-01	87.9%	70.7%
3sqiA01	1.10.150.540	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.73	38.0	3.73e-01	92.3%	46.5%
4abmD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.72	54.0	5.83e-01	100.0%	93.5%
2l3lA01	1.20.58.1250	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain	0.72	49.0	4.63e-01	93.4%	59.4%
2f8lA01	1.10.150.470	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.72	50.0	5.25e-01	72.5%	80.2%
2etdA00	1.20.1440.20	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain	0.72	64.0	5.57e-01	100.0%	84.4%
3ousA00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.71	55.0	5.75e-01	81.3%	96.3%
8a1gC01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.71	57.0	4.55e-01	100.0%	43.6%
3vouB00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.71	58.0	5.13e-01	90.1%	63.2%
1s35A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	48.0	4.52e-01	96.7%	58.2%
4iloA00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.70	54.0	3.93e-01	96.7%	31.4%
7cyuA01	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.70	38.0	4.69e-01	70.3%	86.0%
2p5tA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.69	48.0	4.83e-01	100.0%	70.7%
8ctsB01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.69	51.0	5.23e-01	78.0%	88.5%
2co9A00	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.68	39.0	3.75e-01	73.6%	50.0%
1gvnA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.68	47.0	4.80e-01	95.6%	73.6%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.68	49.0	3.73e-01	100.0%	32.4%
1j1jA02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.67	39.0	4.09e-01	81.3%	61.2%
2xheA03	3.90.830.10	Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a	0.67	49.0	4.52e-01	82.4%	58.7%
2hz8A00	1.20.120.660	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain	0.67	43.0	3.97e-01	85.7%	51.3%
1yozA00	1.10.3200.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like	0.67	37.0	3.49e-01	96.7%	43.4%
2d9dA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.66	38.0	3.93e-01	81.3%	57.3%
3terA00	1.10.287.3550	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.66	59.0	5.32e-01	100.0%	72.3%
1m6nA04	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.66	48.0	4.24e-01	97.8%	51.9%
3fblA00	1.20.58.800	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.65	35.0	3.73e-01	98.9%	56.1%
3hr0B01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.65	49.0	5.23e-01	100.0%	93.7%
2o36A01	1.20.1050.40	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1	0.65	43.0	3.83e-01	87.9%	47.7%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.64	46.0	4.03e-01	100.0%	48.9%
3l1nA02	1.20.1280.140	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.64	40.0	4.12e-01	100.0%	65.5%
3axjB02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.64	39.0	4.08e-01	89.0%	65.9%
2ieqA00	1.20.5.300	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.64	52.0	5.32e-01	100.0%	90.9%
1wdzA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.64	59.0	4.30e-01	100.0%	39.4%
3edvB01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.64	50.0	4.34e-01	95.6%	55.9%
2oexA01	1.20.120.560	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain	0.63	57.0	4.81e-01	100.0%	60.8%
4dylA02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.63	53.0	5.28e-01	96.7%	86.2%
1h3lB00	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.63	37.0	3.99e-01	100.0%	66.7%
4oogC01	1.10.1520.10	Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain	0.63	48.0	4.01e-01	97.8%	46.3%
7r97A01	1.10.1520.10	Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain	0.62	45.0	3.82e-01	91.2%	46.6%
3a06B03	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.62	36.0	3.70e-01	76.9%	59.1%
3cazB00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.62	56.0	4.21e-01	100.0%	42.4%
3pe0A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.61	48.0	4.55e-01	98.9%	70.8%
3layF00	1.20.120.1490	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.61	46.0	4.86e-01	97.8%	96.2%
1cnt200	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.61	46.0	4.07e-01	80.2%	67.7%
2v0xA01	1.10.287.3160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.60	56.0	4.49e-01	100.0%	68.5%
2q0oC00	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.60	44.0	4.53e-01	95.6%	82.6%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.60	55.0	4.53e-01	100.0%	89.3%
1cpcA00	1.10.490.20	Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins	0.59	43.0	3.60e-01	76.9%	59.9%
3gi7A00	1.20.1270.180	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.59	46.0	4.48e-01	100.0%	74.8%
1e1dA02	1.20.1270.20	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.59	37.0	3.90e-01	84.6%	69.0%
4hr1A00	1.20.1270.410	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.59	45.0	4.13e-01	94.5%	62.7%
1br2A03	1.20.120.720	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain	0.58	51.0	5.04e-01	94.5%	100.0%
2gtsA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.57	44.0	4.73e-01	98.9%	98.7%
4tvsA00	3.40.50.12190	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.57	42.0	3.15e-01	78.0%	51.3%
1wleA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.55	49.0	4.56e-01	96.7%	77.2%
3o6xA02	1.20.120.1560	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.55	48.0	4.16e-01	100.0%	69.6%
4cqiA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	45.0	4.26e-01	96.7%	76.6%
2dq0A01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.54	48.0	4.52e-01	96.7%	81.3%
3rv0C02	1.10.1520.10	Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain	0.54	43.0	3.67e-01	85.7%	58.3%
4usaA02	1.10.150.120	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain	0.53	38.0	3.48e-01	74.7%	64.7%
3ofnY00	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.53	46.0	4.25e-01	96.7%	74.8%
3ni7A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.53	41.0	3.36e-01	95.6%	44.3%
2k3oA00	1.10.274.60	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain	0.52	37.0	3.33e-01	73.6%	72.9%
2qkwA00	1.20.1270.140	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto	0.52	36.0	3.56e-01	89.0%	66.3%
5ha6B00	1.10.287.210	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.52	41.0	4.32e-01	100.0%	100.0%
1xrsA00	3.20.20.440	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › D-Lysine 5,6-aminomutase alpha subunit	0.51	43.0	2.79e-01	100.0%	70.3%
2hxoA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.51	40.0	3.46e-01	95.6%	54.2%
2qe7G01	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.51	45.0	4.44e-01	98.9%	95.9%
1x46A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.50	40.0	3.38e-01	86.8%	52.0%

ECOD (56)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5057879	5054.1.1.8 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2	0.85	79.0	7.12e-01	100.0%	81.7%
3881583	310.2.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF	0.80	63.0	5.04e-01	100.0%	44.7%
3756047	192.29.1.243 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Fy-3	0.80	66.0	6.69e-01	98.9%	87.8%
3694833	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.80	56.0	4.89e-01	96.7%	50.8%
5056477	5058.1.1.2 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st	0.77	54.0	5.49e-01	100.0%	73.3%
4058767	7015.1.1.0 ↗	alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain	0.77	55.0	4.74e-01	100.0%	48.6%
4291487	1128.1.1.2 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2	0.73	36.0	3.41e-01	100.0%	38.2%
3204262	5051.1.1.15 ↗	alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › K_trans	0.73	65.0	4.50e-01	98.9%	75.4%
3691415	2004.1.1.748 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_23, SbcC_Walker_B	0.73	56.0	3.38e-01	79.1%	24.6%
4300897	5094.1.1.1 ↗	a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH	0.73	62.0	5.43e-01	100.0%	63.1%
3619641	604.1.1.154 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021	0.73	52.0	5.00e-01	89.0%	64.8%
4246296	3826.1.1.72 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Microcin	0.72	39.0	3.75e-01	98.9%	44.8%
5036615	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.72	54.0	5.33e-01	97.8%	75.8%
3258290	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.71	41.0	4.49e-01	92.3%	69.3%
3563871	603.1.1.121 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821	0.71	51.0	4.75e-01	95.6%	60.0%
3216082	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.70	48.0	4.47e-01	90.1%	56.5%
3659915	192.7.1.45 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Na_sulph_symp	0.70	44.0	4.79e-01	87.9%	77.3%
5012657	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.69	47.0	4.68e-01	98.9%	67.4%
3971610	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.69	64.0	4.70e-01	100.0%	42.3%
3715005	604.8.1.0 ↗	alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo	0.69	55.0	4.57e-01	100.0%	49.4%
3506153	190.1.1.1 ↗	alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box	0.68	40.0	4.19e-01	73.6%	63.9%
4965530	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.68	52.0	5.16e-01	98.9%	77.9%
3588971	6026.1.1.0 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain	0.68	44.0	4.85e-01	89.0%	81.3%
3612815	101.35.1.0 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX	0.67	38.0	3.48e-01	100.0%	42.5%
4026470	3871.1.1.1 ↗	alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN	0.67	51.0	4.28e-01	100.0%	48.4%
3990182	3922.1.1.226 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Fy-3	0.67	59.0	5.47e-01	100.0%	76.5%
3528691	601.19.1.20 ↗	alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Fy-3	0.67	61.0	5.44e-01	98.9%	76.8%
3262519	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.67	50.0	3.96e-01	100.0%	38.4%
4025391	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.66	42.0	4.31e-01	96.7%	68.2%
3964578	5094.1.1.1 ↗	a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH	0.65	52.0	4.49e-01	97.8%	55.7%
3973899	5086.1.1.92 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE	0.65	60.0	5.08e-01	100.0%	80.7%
4949396	606.1.1.0 ↗	alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain	0.65	55.0	5.52e-01	96.7%	95.6%
3185821	4044.1.1.0 ↗	alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins	0.64	37.0	4.06e-01	89.0%	69.3%
3733140	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	58.0	4.83e-01	100.0%	60.0%
3642640	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.63	57.0	3.83e-01	100.0%	28.1%
3476331	603.2.1.0 ↗	alpha bundles › STAT-like › STAT › STAT	0.63	50.0	4.55e-01	100.0%	63.2%
5002671	3755.3.1.637 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121	0.62	56.0	4.58e-01	96.7%	80.6%
3697355	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.62	56.0	4.70e-01	100.0%	60.6%
4017235	190.1.1.0 ↗	alpha arrays › HMG-box-like › HMG-box › HMG-box	0.62	38.0	3.42e-01	85.7%	46.7%
4025205	601.19.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein	0.61	56.0	4.70e-01	100.0%	62.0%
3713209	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.61	54.0	5.19e-01	96.7%	82.9%
3598168	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.61	57.0	4.59e-01	100.0%	90.3%
3702347	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.61	55.0	4.38e-01	97.8%	50.9%
3920552	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.60	54.0	4.07e-01	97.8%	98.1%
3305747	192.2.1.18 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING	0.59	53.0	4.63e-01	100.0%	89.3%
3289986	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.59	54.0	4.55e-01	100.0%	80.0%
4342809	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.58	52.0	4.71e-01	100.0%	80.8%
4977416	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.58	52.0	3.79e-01	97.8%	100.0%
4192675	632.15.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN)	0.58	43.0	4.32e-01	78.0%	98.9%
4969098	3926.1.1.0 ↗	alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D	0.58	52.0	4.10e-01	96.7%	59.4%
3795697	101.1.4.0 ↗	alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like	0.57	28.0	3.30e-01	70.3%	66.2%
5024245	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.57	51.0	4.81e-01	100.0%	87.3%
4663129	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.56	50.0	3.50e-01	96.7%	32.2%
4372538	106.1.1.1 ↗	alpha arrays › Globin-like › Globin-like › Globin-like › Globin	0.56	39.0	3.40e-01	71.4%	65.3%
4945751	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.53	46.0	4.39e-01	98.9%	93.6%
3482686	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.52	35.0	3.61e-01	91.2%	70.0%

D6 medium residues 1520-1603

PDB

D7 medium residues 1604-1653

PDB