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IMGVR_UViG_3300028048_000061-3300028048-Ga0256405_1000034376

Arc-Vir

IMGVR_UViG_3300028048_000061-3300028048-Ga0256405_1000034376

Quality

96.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-70
PDB
Domain cluster: representative
CATH (76)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.92 83.0 8.21e-01 100.0% 91.8%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.91 81.0 5.43e-01 100.0% 28.3%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.89 80.0 7.10e-01 100.0% 70.5%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 67.0 7.38e-01 92.9% 98.2%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.87 81.0 7.00e-01 100.0% 77.7%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.87 79.0 6.26e-01 97.1% 57.7%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.87 78.0 7.97e-01 95.7% 100.0%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.86 80.0 5.42e-01 100.0% 39.7%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.86 80.0 6.19e-01 100.0% 49.3%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.86 71.0 6.94e-01 91.4% 80.3%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 76.0 6.76e-01 98.6% 69.8%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.86 80.0 7.12e-01 100.0% 95.8%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.86 71.0 6.88e-01 97.1% 79.5%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.85 79.0 5.66e-01 100.0% 37.6%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.85 72.0 7.51e-01 97.1% 100.0%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.85 79.0 6.14e-01 100.0% 65.5%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 77.0 6.44e-01 100.0% 61.4%
4ciuA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.84 74.0 5.26e-01 98.6% 34.9%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.84 77.0 6.68e-01 100.0% 72.5%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.83 76.0 6.89e-01 100.0% 75.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 76.0 5.59e-01 100.0% 41.0%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.83 72.0 6.67e-01 94.3% 96.6%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 61.0 6.83e-01 97.1% 100.0%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.83 76.0 6.33e-01 100.0% 60.3%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 76.0 7.17e-01 100.0% 91.5%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.83 75.0 6.90e-01 100.0% 89.9%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.82 75.0 5.92e-01 100.0% 51.1%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.82 65.0 5.23e-01 95.7% 45.8%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.82 73.0 6.46e-01 97.1% 100.0%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.82 73.0 7.10e-01 100.0% 94.8%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.81 74.0 5.78e-01 100.0% 49.3%
3ibpA01 1.20.58.850 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 69.0 6.92e-01 91.4% 98.6%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 71.0 7.15e-01 95.7% 95.7%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 72.0 5.52e-01 100.0% 45.2%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.80 73.0 6.45e-01 100.0% 71.4%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.79 71.0 6.20e-01 100.0% 69.8%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 74.0 6.38e-01 100.0% 68.0%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.79 73.0 7.00e-01 100.0% 87.5%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.79 70.0 6.85e-01 98.6% 94.7%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 66.0 5.92e-01 100.0% 67.0%
2bduA02 1.10.150.340 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain 0.78 53.0 5.27e-01 75.7% 67.6%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 65.0 6.65e-01 100.0% 97.1%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.78 69.0 6.27e-01 100.0% 76.6%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.78 69.0 5.99e-01 100.0% 66.4%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.78 69.0 5.45e-01 100.0% 48.9%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.77 70.0 6.14e-01 100.0% 77.5%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.77 68.0 5.10e-01 100.0% 40.0%
3tc1B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.77 70.0 4.50e-01 100.0% 36.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 67.0 6.54e-01 100.0% 98.7%
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 68.0 6.60e-01 97.1% 98.7%
4lwsB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 67.0 6.29e-01 100.0% 85.2%
1ki1B01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.77 69.0 4.92e-01 100.0% 84.9%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 66.0 6.75e-01 97.1% 100.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.76 66.0 5.76e-01 97.1% 64.2%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 66.0 6.65e-01 98.6% 97.2%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.76 53.0 4.34e-01 72.9% 41.1%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 68.0 5.91e-01 98.6% 67.3%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.75 63.0 6.19e-01 100.0% 88.2%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.75 67.0 4.73e-01 100.0% 34.8%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 66.0 5.82e-01 100.0% 70.5%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.74 65.0 4.99e-01 100.0% 43.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 65.0 5.85e-01 100.0% 75.8%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 66.0 5.39e-01 100.0% 74.2%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 65.0 6.36e-01 100.0% 90.9%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.73 61.0 6.03e-01 92.9% 98.6%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 61.0 6.03e-01 97.1% 97.3%
2xgjA04 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.71 66.0 5.23e-01 100.0% 56.1%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 61.0 6.12e-01 100.0% 97.2%
1ykeD00 6.10.280.10 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator complex, subunit Med21 0.67 56.0 4.90e-01 97.1% 60.2%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 57.0 4.96e-01 100.0% 65.5%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.66 47.0 3.36e-01 74.3% 37.7%
3itfA00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 57.0 4.91e-01 100.0% 64.0%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 55.0 5.04e-01 100.0% 75.3%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 55.0 5.45e-01 98.6% 94.6%
2fzlA02 6.10.140.1180 Special › Helix non-globular › Helix Hairpins › 0.62 50.0 5.32e-01 97.1% 98.4%
2x6hA03 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.57 46.0 3.36e-01 88.6% 42.0%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4197529 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.90 85.0 7.13e-01 100.0% 66.4%
1106555 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.90 72.0 7.42e-01 94.3% 89.4%
4572974 3922.1.1.79 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C 0.89 76.0 6.27e-01 100.0% 54.8%
3745112 3755.3.1.298 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING 0.89 83.0 6.77e-01 100.0% 58.3%
3930829 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.89 80.0 7.81e-01 100.0% 89.3%
5036722 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.89 83.0 6.56e-01 100.0% 53.4%
4128407 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.89 84.0 7.01e-01 100.0% 63.6%
4034092 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.88 82.0 8.00e-01 100.0% 97.3%
4031283 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 83.0 6.26e-01 100.0% 74.7%
4024006 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 83.0 5.45e-01 100.0% 28.0%
3906631 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.88 77.0 6.48e-01 98.6% 59.1%
3613659 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 82.0 6.08e-01 100.0% 42.7%
3694558 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.88 82.0 6.05e-01 100.0% 42.4%
3775753 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.88 81.0 4.56e-01 100.0% 11.3%
5002102 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 82.0 5.99e-01 100.0% 98.8%
3573035 109.4.1.3370 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PL48 0.88 82.0 6.42e-01 100.0% 54.1%
5031890 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.88 82.0 5.44e-01 100.0% 28.6%
3204772 192.1.1.31 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › Cep57_MT_bd 0.88 82.0 7.14e-01 100.0% 70.0%
4017817 3922.1.1.229 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Cep57_MT_bd 0.88 82.0 6.34e-01 100.0% 50.0%
4303085 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.87 81.0 6.65e-01 100.0% 58.3%
5075803 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.87 81.0 6.38e-01 100.0% 51.9%
3595707 5086.1.1.118 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp 0.87 81.0 6.47e-01 100.0% 53.8%
3925617 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.87 82.0 7.59e-01 100.0% 82.4%
3849660 11.2.1.25 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PL48 0.87 81.0 6.45e-01 100.0% 53.8%
4477580 5086.1.1.118 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp 0.87 81.0 7.54e-01 100.0% 83.5%
3786359 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.87 82.0 7.10e-01 100.0% 77.0%
3285723 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.87 76.0 5.49e-01 95.7% 37.1%
3477269 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.87 81.0 6.08e-01 100.0% 49.7%
3529707 4.1.1.453 beta barrels › SH3 › SH3 › SH3 › HR1_TOCA 0.87 81.0 7.23e-01 100.0% 73.7%
3738041 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.87 81.0 7.50e-01 100.0% 82.4%
3494198 328.7.1.0 a+b two layers › IF3-like › Smr domain › Smr domain 0.87 81.0 5.72e-01 100.0% 36.8%
3626769 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.86 81.0 7.35e-01 100.0% 77.8%
None 0.86 80.0 6.40e-01 100.0% 54.6%
3931719 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.86 80.0 6.29e-01 100.0% 54.1%
3393794 3922.1.1.211 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C 0.86 80.0 6.29e-01 100.0% 52.6%
3628093 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.86 79.0 6.83e-01 100.0% 73.3%
5024408 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.86 80.0 5.72e-01 100.0% 37.8%
5054861 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.86 80.0 4.72e-01 100.0% 16.6%
3217110 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.85 78.0 7.32e-01 100.0% 94.1%
3710275 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.85 79.0 5.28e-01 100.0% 29.2%
4018104 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 79.0 5.04e-01 100.0% 40.3%
5036205 2004.1.1.348 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SbcC_Walker_B 0.85 79.0 4.41e-01 100.0% 43.0%
4542972 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.85 78.0 5.47e-01 100.0% 39.5%
3286277 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.85 77.0 5.54e-01 97.1% 37.8%
3562849 148.1.3.254 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th 0.85 78.0 5.31e-01 100.0% 54.3%
3671241 109.4.1.128 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 0.85 78.0 4.97e-01 100.0% 23.9%
3755586 3291.1.1.118 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF9 0.84 78.0 6.09e-01 100.0% 50.0%
3541873 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.84 79.0 6.11e-01 100.0% 50.0%
4021462 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.84 77.0 4.46e-01 100.0% 37.7%
3915380 192.5.1.25 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PTHB1_hp 0.84 78.0 7.13e-01 100.0% 78.9%
3913300 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.84 78.0 5.93e-01 100.0% 83.3%
3187178 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.83 76.0 5.43e-01 100.0% 35.9%
3928718 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.83 76.0 5.95e-01 100.0% 50.0%
3861615 150.1.1.190 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C 0.83 76.0 6.70e-01 100.0% 77.0%
4943532 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.83 74.0 7.41e-01 95.7% 100.0%
5079565 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.83 76.0 5.58e-01 100.0% 46.3%
3903422 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.83 77.0 6.30e-01 100.0% 70.0%
3611700 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 77.0 4.91e-01 100.0% 24.0%
4015178 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.82 75.0 5.73e-01 100.0% 72.9%
3832457 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 76.0 5.12e-01 100.0% 39.1%
3200160 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.82 74.0 6.35e-01 100.0% 64.5%
3607135 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 75.0 5.94e-01 100.0% 74.1%
3831567 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 75.0 5.52e-01 100.0% 41.8%
3938243 3065.1.1.1 alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › ANIS5_cation-bd 0.81 70.0 4.71e-01 95.7% 26.9%
4623646 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.80 71.0 4.37e-01 100.0% 18.3%
4771589 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.80 73.0 6.45e-01 100.0% 71.4%
3278124 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.79 68.0 5.64e-01 98.6% 55.0%
222991 192.10.1.1 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N 0.79 70.0 6.45e-01 100.0% 77.2%
3564741 3860.1.1.322 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › KELK 0.79 70.0 4.39e-01 100.0% 20.3%
3220596 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 69.0 5.88e-01 100.0% 61.7%
5079778 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.78 69.0 4.18e-01 100.0% 15.6%
5028533 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 69.0 5.60e-01 100.0% 53.1%
3887920 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 67.0 5.20e-01 100.0% 47.7%
3598199 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.76 68.0 4.96e-01 100.0% 47.6%
3268739 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.75 65.0 5.84e-01 98.6% 70.0%
3703582 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.73 64.0 5.34e-01 100.0% 56.0%
3717826 547.1.1.0 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain 0.73 59.0 5.08e-01 85.7% 58.1%
4026047 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.72 59.0 5.49e-01 90.0% 71.8%
3212006 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.72 64.0 5.21e-01 100.0% 91.5%
3394753 192.5.1.12 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PH_19 0.72 59.0 5.94e-01 98.6% 92.9%
3720226 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.69 57.0 4.64e-01 92.9% 51.9%
3384661 601.1.2.90 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Not3 0.68 59.0 4.89e-01 100.0% 53.8%
5024040 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.66 56.0 3.52e-01 94.3% 18.1%
3773794 6170.1.1.25 alpha bundles › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › PF30874 0.57 47.0 4.56e-01 98.6% 82.4%
D2 high residues 96-186
PDB
Domain cluster: representative
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gxaE01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.72 40.0 4.42e-01 100.0% 68.5%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 39.0 3.70e-01 100.0% 52.3%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.63 40.0 4.51e-01 100.0% 86.6%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 42.0 3.94e-01 100.0% 56.4%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 40.0 3.91e-01 100.0% 63.3%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 39.0 3.76e-01 100.0% 60.4%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.57 39.0 3.01e-01 72.5% 45.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.56 39.0 3.65e-01 100.0% 59.1%
1bf3A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 39.0 2.94e-01 72.5% 36.7%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 41.0 4.66e-01 100.0% 98.6%
2wcjA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.56 42.0 3.63e-01 80.2% 65.2%
1dqeA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.55 42.0 3.64e-01 81.3% 65.7%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 32.0 3.17e-01 100.0% 53.5%
2qcvA01 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.54 43.0 3.10e-01 87.9% 85.7%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 47.0 3.11e-01 100.0% 57.7%
2xzmV01 1.10.60.20 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 0.53 33.0 3.99e-01 73.6% 96.7%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.52 41.0 4.28e-01 100.0% 89.4%
2lyiA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.52 41.0 3.54e-01 86.8% 66.2%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.54e-01 100.0% 58.6%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3959204 102.1.4.2 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › Nop C-terminal domain › Transposase_20 0.79 73.0 6.57e-01 98.9% 79.2%
3547935 3204.1.1.0 extended segments › N-terminal regulatory segment of carnitine palmitoyltransferase 1A › N-terminal regulatory segment of carnitine palmitoyltransferase 1A › N-terminal regulatory segment of carnitine palmitoyltransferase 1A 0.72 56.0 5.28e-01 96.7% 69.1%
3262801 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.66 46.0 4.15e-01 72.5% 54.4%
5010209 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.64 48.0 3.64e-01 79.1% 37.6%
4945610 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.62 41.0 4.00e-01 100.0% 62.0%
5078048 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 38.0 4.14e-01 100.0% 76.0%
3343651 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.61 40.0 3.14e-01 100.0% 33.0%
3812802 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.60 48.0 3.98e-01 83.5% 72.3%
4280209 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.60 45.0 3.38e-01 78.0% 45.1%
1070258 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.59 40.0 4.65e-01 98.9% 100.0%
5054990 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 38.0 3.31e-01 100.0% 43.5%
4994698 4041.1.1.0 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase 0.58 52.0 4.06e-01 100.0% 71.8%
3863075 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 41.0 3.08e-01 74.7% 70.6%
3386988 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.57 51.0 3.82e-01 100.0% 91.1%
3801688 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 39.0 3.70e-01 98.9% 61.0%
4978226 171.1.1.3 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_2 0.57 52.0 4.45e-01 100.0% 95.0%
3697490 3621.1.1.0 alpha arrays › Dipeptidyl-peptidase 2 helical domain › Dipeptidyl-peptidase 2 helical domain › Dipeptidyl-peptidase 2 helical domain 0.56 46.0 3.89e-01 92.3% 55.0%
4467738 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.56 39.0 3.95e-01 100.0% 73.3%
4177339 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 50.0 3.70e-01 100.0% 54.8%
3938862 604.1.1.98 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 0.53 41.0 3.83e-01 100.0% 66.4%
3242447 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 38.0 3.65e-01 100.0% 65.7%
4954644 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.52 39.0 3.57e-01 100.0% 60.0%
None 0.52 47.0 3.67e-01 100.0% 74.2%
4975796 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.51 44.0 4.33e-01 92.3% 92.6%
5030543 159.1.3.0 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › putative NTP pyrophosphohydrolase Exig_1061 0.51 40.0 3.94e-01 100.0% 76.0%