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IMGVR_UViG_3300028453_000003-3300028453-Ga0307246_100016626
Arc-VirIMGVR_UViG_3300028453_000003-3300028453-Ga0307246_100016626
Identity
- Kingdom:
- archaea
Quality
87.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 18-177
Domain cluster:
representative
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.75 | 70.0 | 6.26e-01 | 100.0% | 86.8% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.69 | 45.0 | 4.90e-01 | 80.0% | 78.5% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.67 | 62.0 | 5.52e-01 | 100.0% | 84.3% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.67 | 55.0 | 5.85e-01 | 90.6% | 100.0% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 54.0 | 4.44e-01 | 84.4% | 82.3% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 41.0 | 5.01e-01 | 70.0% | 98.0% |
| 5bqnA02 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.66 | 47.0 | 3.58e-01 | 73.1% | 66.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 46.0 | 5.26e-01 | 88.1% | 99.1% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 42.0 | 5.05e-01 | 83.7% | 100.0% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.65 | 41.0 | 4.71e-01 | 83.7% | 88.4% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.64 | 46.0 | 4.57e-01 | 73.8% | 100.0% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 46.0 | 4.98e-01 | 90.6% | 90.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 40.0 | 4.43e-01 | 77.5% | 80.3% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 46.0 | 5.13e-01 | 88.7% | 100.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 44.0 | 5.06e-01 | 71.2% | 98.3% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.63 | 41.0 | 4.29e-01 | 80.6% | 70.7% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.63 | 47.0 | 4.05e-01 | 76.9% | 77.7% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 46.0 | 5.08e-01 | 94.4% | 100.0% |
| 3f1bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 41.0 | 3.96e-01 | 93.1% | 58.5% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 45.0 | 4.61e-01 | 90.6% | 79.5% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 49.0 | 4.13e-01 | 84.4% | 86.8% |
| 1tf5A04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.61 | 46.0 | 4.41e-01 | 77.5% | 100.0% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.61 | 45.0 | 4.38e-01 | 76.9% | 100.0% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 35.0 | 4.20e-01 | 88.7% | 85.0% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 47.0 | 4.26e-01 | 81.9% | 94.4% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 35.0 | 4.23e-01 | 85.0% | 91.3% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 47.0 | 4.47e-01 | 85.0% | 97.3% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 41.0 | 4.55e-01 | 86.3% | 91.5% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 36.0 | 3.83e-01 | 71.2% | 70.5% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.57 | 45.0 | 4.51e-01 | 83.1% | 93.8% |
| 3kbtA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 38.0 | 3.13e-01 | 71.9% | 38.0% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.56 | 41.0 | 4.40e-01 | 90.6% | 89.5% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 39.0 | 3.97e-01 | 81.2% | 71.3% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.56 | 39.0 | 4.27e-01 | 96.9% | 85.7% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 37.0 | 3.73e-01 | 80.6% | 66.5% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 35.0 | 3.68e-01 | 75.6% | 68.5% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 36.0 | 4.17e-01 | 73.1% | 91.5% |
| 6l3tA01 | 1.20.1440.80 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain | 0.55 | 43.0 | 4.00e-01 | 81.9% | 72.4% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.55 | 45.0 | 4.74e-01 | 100.0% | 97.9% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.54 | 44.0 | 3.63e-01 | 88.1% | 100.0% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 40.0 | 4.38e-01 | 89.4% | 94.6% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.54 | 42.0 | 4.48e-01 | 81.9% | 95.0% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 37.0 | 3.66e-01 | 81.9% | 65.7% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.53 | 42.0 | 4.02e-01 | 83.7% | 93.0% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 35.0 | 3.58e-01 | 78.1% | 67.7% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 36.0 | 4.03e-01 | 71.9% | 88.1% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 39.0 | 4.22e-01 | 78.8% | 100.0% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 44.0 | 3.75e-01 | 97.5% | 54.2% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.52 | 41.0 | 3.57e-01 | 83.1% | 85.7% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.51 | 45.0 | 4.08e-01 | 96.9% | 87.6% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 46.0 | 4.22e-01 | 98.8% | 80.4% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.50 | 36.0 | 3.66e-01 | 74.4% | 81.1% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.50 | 40.0 | 3.43e-01 | 83.7% | 85.1% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.50 | 34.0 | 3.97e-01 | 70.6% | 97.3% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 45.0 | 3.74e-01 | 98.1% | 87.4% |
| 8itfR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 40.0 | 3.38e-01 | 93.1% | 48.9% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.50 | 42.0 | 4.00e-01 | 90.6% | 81.2% |
ECOD (74)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3165030 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.81 | 75.0 | 7.01e-01 | 100.0% | 98.5% |
| 3620725 | 5041.1.1.17 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Periphilin_C | 0.79 | 47.0 | 5.75e-01 | 97.5% | 90.5% |
| 4135589 | 601.19.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein | 0.77 | 72.0 | 5.64e-01 | 100.0% | 82.8% |
| 4026473 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.74 | 62.0 | 6.30e-01 | 88.7% | 93.1% |
| 4026661 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.74 | 54.0 | 4.29e-01 | 74.4% | 75.3% |
| 4026128 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.72 | 60.0 | 6.26e-01 | 88.1% | 100.0% |
| 3953233 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.72 | 67.0 | 5.17e-01 | 100.0% | 57.6% |
| 4508628 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.71 | 66.0 | 5.74e-01 | 100.0% | 73.6% |
| 4977278 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.71 | 56.0 | 4.27e-01 | 80.6% | 65.2% |
| 3885225 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.71 | 65.0 | 6.44e-01 | 98.1% | 98.2% |
| 4575614 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.69 | 64.0 | 5.37e-01 | 100.0% | 69.2% |
| 4188455 | 601.19.1.19 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › ATP-synt_A | 0.69 | 63.0 | 5.62e-01 | 100.0% | 76.2% |
| None | — | 0.68 | 63.0 | 4.21e-01 | 100.0% | 33.7% | |
| 3932046 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.68 | 39.0 | 5.08e-01 | 78.1% | 100.0% |
| 4979116 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.68 | 43.0 | 4.95e-01 | 78.1% | 87.8% |
| 4068279 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.67 | 62.0 | 5.25e-01 | 100.0% | 73.5% |
| 4024699 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.67 | 56.0 | 5.82e-01 | 91.3% | 97.2% |
| 3589614 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.67 | 40.0 | 4.55e-01 | 73.1% | 77.2% |
| 3598318 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.66 | 50.0 | 4.37e-01 | 78.1% | 92.3% |
| 4233725 | 161.1.1.1 ↗ | alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › SecA_SW | 0.66 | 51.0 | 5.09e-01 | 80.6% | 93.9% |
| 4126682 | 192.29.1.116 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Apolipoprotein | 0.65 | 57.0 | 5.32e-01 | 99.4% | 77.0% |
| 3495555 | 5079.1.1.0 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain | 0.64 | 57.0 | 5.25e-01 | 99.4% | 79.5% |
| 4423918 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.63 | 57.0 | 4.90e-01 | 98.1% | 72.4% |
| 4936552 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.63 | 51.0 | 5.31e-01 | 93.8% | 90.7% |
| 4064125 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 48.0 | 3.16e-01 | 78.1% | 28.5% |
| 3937340 | 150.1.1.105 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › ATG2_CAD | 0.62 | 40.0 | 3.88e-01 | 81.9% | 57.2% |
| 3242888 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.62 | 37.0 | 4.04e-01 | 75.0% | 69.6% |
| 3509455 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 55.0 | 5.52e-01 | 98.1% | 98.8% |
| 3807513 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.61 | 34.0 | 3.66e-01 | 70.6% | 61.5% |
| 4999807 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.61 | 42.0 | 3.99e-01 | 94.4% | 58.0% |
| 3581398 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 46.0 | 4.96e-01 | 90.6% | 96.3% |
| 3970386 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 45.0 | 4.83e-01 | 93.8% | 93.3% |
| 5064797 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.59 | 47.0 | 4.23e-01 | 83.1% | 92.3% |
| 3662200 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.59 | 41.0 | 4.21e-01 | 78.8% | 72.3% |
| 3606689 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.59 | 44.0 | 3.73e-01 | 75.6% | 78.4% |
| 3587197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 49.0 | 5.06e-01 | 96.9% | 93.3% |
| 3766742 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 40.0 | 4.58e-01 | 77.5% | 94.8% |
| 3345599 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.59 | 53.0 | 5.10e-01 | 98.1% | 96.1% |
| 3709193 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.58 | 47.0 | 3.91e-01 | 85.6% | 77.1% |
| 3287581 | 601.4.1.54 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF28326 | 0.58 | 44.0 | 4.57e-01 | 93.8% | 86.9% |
| 3978381 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 41.0 | 4.45e-01 | 91.9% | 89.2% |
| 3831792 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.57 | 47.0 | 4.08e-01 | 88.7% | 70.2% |
| 4595958 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.57 | 38.0 | 4.41e-01 | 80.0% | 97.3% |
| 3655293 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.57 | 47.0 | 4.32e-01 | 86.9% | 97.6% |
| 4348504 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 45.0 | 4.47e-01 | 84.4% | 84.7% |
| 3685989 | 601.1.2.115 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DUF3433 | 0.56 | 47.0 | 4.63e-01 | 90.6% | 90.3% |
| 5023098 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.56 | 38.0 | 4.27e-01 | 88.7% | 89.6% |
| 3591522 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.56 | 52.0 | 4.56e-01 | 100.0% | 87.8% |
| 3842287 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.55 | 38.0 | 3.93e-01 | 80.0% | 73.3% |
| 4085203 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.55 | 39.0 | 4.26e-01 | 85.0% | 88.5% |
| 3267361 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.55 | 52.0 | 4.72e-01 | 100.0% | 86.3% |
| 3843153 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 34.0 | 3.70e-01 | 74.4% | 72.6% |
| 3194102 | 601.1.1.90 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3433 | 0.55 | 44.0 | 4.62e-01 | 90.6% | 95.2% |
| 3986928 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.55 | 51.0 | 4.72e-01 | 100.0% | 90.0% |
| 3224284 | 603.3.1.0 ↗ | alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein | 0.54 | 42.0 | 4.14e-01 | 81.9% | 99.4% |
| 3659874 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.54 | 44.0 | 4.63e-01 | 93.1% | 93.8% |
| 5073511 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.54 | 45.0 | 4.45e-01 | 89.4% | 86.5% |
| 3831677 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.54 | 49.0 | 4.34e-01 | 100.0% | 95.7% |
| 5055160 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.54 | 42.0 | 4.31e-01 | 86.3% | 85.8% |
| 3932036 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.53 | 48.0 | 3.81e-01 | 96.2% | 87.3% |
| 3919688 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.53 | 42.0 | 3.71e-01 | 83.7% | 80.4% |
| 3306310 | 192.29.1.115 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 | 0.53 | 40.0 | 4.20e-01 | 79.4% | 84.7% |
| 4426034 | 3882.1.1.1 ↗ | alpha bundles › Atg17 › Atg17 › Atg17 › ATG17_like | 0.53 | 48.0 | 3.94e-01 | 98.1% | 85.6% |
| 5028028 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 42.0 | 4.51e-01 | 90.6% | 100.0% |
| 3934550 | 3562.1.1.1 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Orai-1 | 0.53 | 39.0 | 3.71e-01 | 84.4% | 64.2% |
| 5035637 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.52 | 49.0 | 4.69e-01 | 100.0% | 90.6% |
| 3904257 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.52 | 43.0 | 4.26e-01 | 87.5% | 92.4% |
| 3442053 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 47.0 | 4.38e-01 | 98.8% | 92.5% |
| 3248869 | 601.15.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) | 0.52 | 47.0 | 4.47e-01 | 98.8% | 85.3% |
| 3926712 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.52 | 45.0 | 3.67e-01 | 96.2% | 50.5% |
| 3453950 | 3559.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 | 0.51 | 36.0 | 4.12e-01 | 88.1% | 100.0% |
| 4872033 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 42.0 | 3.73e-01 | 96.2% | 62.3% |
| 3932516 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.51 | 43.0 | 3.58e-01 | 95.0% | 50.0% |
| 3797875 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 43.0 | 3.36e-01 | 92.5% | 47.5% |
D2
high
residues 179-239
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2g23K04 | 2.60.40.420 | Mainly Beta › Sandwich › Immunoglobulin-like › Cupredoxins - blue copper proteins | 0.59 | 50.0 | 3.64e-01 | 100.0% | 51.1% |
| 2ygrA03 | 3.30.190.20 | Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribosomal protein L1/L10, rRNA-binding domain | 0.57 | 42.0 | 3.50e-01 | 82.0% | 83.5% |
| 2f1fA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.54 | 40.0 | 3.72e-01 | 80.3% | 100.0% |
| 2mj0A00 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.53 | 35.0 | 3.44e-01 | 77.0% | 63.6% |
| 1e3hA03 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.52 | 40.0 | 2.81e-01 | 85.2% | 59.6% |
| 2cuwA00 | 3.30.1280.10 | Alpha Beta › 2-Layer Sandwich › Mth169; Chain: A , › Phosphoribosylformylglycinamidine synthase subunit PurS | 0.52 | 40.0 | 3.66e-01 | 85.2% | 96.4% |
| 3w81A01 | 2.60.40.1500 | Mainly Beta › Sandwich › Immunoglobulin-like › Glycosyl hydrolase domain; family 39 | 0.51 | 37.0 | 2.82e-01 | 82.0% | 49.1% |
| 2wnyA00 | 3.30.1440.10 | Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 | 0.50 | 40.0 | 3.29e-01 | 98.4% | 92.0% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4032640 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.80 | 61.0 | 3.81e-01 | 82.0% | 17.7% |
| 3964369 | 6108.1.1.8 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Phage_Mu_F | 0.78 | 61.0 | 3.99e-01 | 83.6% | 23.2% |
| 4438218 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.56 | 39.0 | 3.36e-01 | 77.0% | 89.1% |
| 3855544 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.54 | 42.0 | 3.56e-01 | 91.8% | 74.8% |
| 3230186 | 10.4.1.19 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › Glycoprotein | 0.51 | 37.0 | 3.15e-01 | 82.0% | 73.9% |
| 3939823 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.51 | 42.0 | 3.20e-01 | 98.4% | 86.7% |