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IMGVR_UViG_3300028570_000845-3300028570-Ga0255341_10128889

Arc-Vir

IMGVR_UViG_3300028570_000845-3300028570-Ga0255341_10128889

Quality

88.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 32-83
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mk7C01 6.10.280.130 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 40.0 3.28e-01 92.3% 33.0%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.65 44.0 3.32e-01 71.2% 68.8%
2m47A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.64 42.0 2.98e-01 100.0% 21.5%
2dqlA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 44.0 3.45e-01 73.1% 71.3%
2fh5A01 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.64 48.0 3.78e-01 84.6% 86.1%
4g6tB00 6.10.20.120 Special › Helix non-globular › Arc Repressor Mutant, subunit A › 0.63 38.0 3.44e-01 92.3% 43.7%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.62 39.0 3.78e-01 100.0% 55.0%
3lltA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.61 46.0 2.89e-01 78.8% 33.9%
3h4rA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.61 42.0 2.83e-01 73.1% 74.4%
3q6aB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.60 38.0 2.85e-01 98.1% 24.6%
3upuA03 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.60 49.0 3.71e-01 92.3% 86.3%
4aghA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.60 43.0 3.81e-01 78.8% 61.3%
1txdA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.59 40.0 3.12e-01 73.1% 81.0%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 43.0 2.92e-01 82.7% 36.0%
6v04A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 40.0 3.03e-01 75.0% 44.1%
2zihC00 1.10.3630.10 Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like 0.57 43.0 2.78e-01 84.6% 63.8%
6scxC01 3.90.79.20 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › 0.56 45.0 3.19e-01 90.4% 66.9%
2xzmG00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.56 41.0 2.83e-01 80.8% 95.8%
3cygA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.55 43.0 3.34e-01 86.5% 87.4%
1h0hB01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 41.0 3.00e-01 82.7% 80.7%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.46e-01 86.5% 84.4%
3jtzA00 3.30.160.390 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain 0.54 41.0 3.61e-01 82.7% 97.4%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 44.0 2.95e-01 94.2% 75.1%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 47.0 3.16e-01 96.2% 63.3%
1z06A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 38.0 2.74e-01 76.9% 57.6%
3nroA00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.53 41.0 2.70e-01 86.5% 54.9%
5hn3A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.52 41.0 2.53e-01 92.3% 94.9%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.51 37.0 3.07e-01 76.9% 79.8%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 39.0 3.33e-01 80.8% 71.8%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3317524 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.81 72.0 4.69e-01 100.0% 23.9%
2764890 4322.1.1.1 a+b complex topology › Flu NP-like › Flu NP-like › Flu NP-like › Flu_NP 0.65 42.0 3.14e-01 98.1% 26.1%
5049862 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 39.0 2.68e-01 92.3% 17.7%
3937747 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 51.0 3.21e-01 92.3% 73.3%
3494392 3937.1.1.2 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.64 47.0 2.84e-01 80.8% 95.1%
3173378 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.62 44.0 2.85e-01 75.0% 38.4%
4931277 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.62 45.0 3.18e-01 76.9% 40.0%
3325708 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.62 42.0 2.61e-01 71.2% 14.3%
3170708 632.1.1.6 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Pho88 0.60 46.0 3.55e-01 94.2% 34.5%
3711985 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.60 47.0 3.09e-01 90.4% 19.6%
1815422 566.1.1.3 alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap 0.59 46.0 3.13e-01 90.4% 73.9%
3988478 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.59 46.0 3.76e-01 86.5% 74.5%
3482756 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 47.0 3.01e-01 90.4% 79.2%
3960676 298.1.1.0 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.58 48.0 2.99e-01 98.1% 87.0%
5048881 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.58 40.0 2.81e-01 73.1% 76.8%
5075144 101.1.9.16 alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.58 44.0 3.98e-01 86.5% 98.7%
3482807 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.58 48.0 3.87e-01 98.1% 83.3%
5023262 327.11.2.82 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF27275 0.57 40.0 3.80e-01 75.0% 100.0%
3326759 284.1.3.1 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 0.57 36.0 3.25e-01 78.8% 44.0%
4029392 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.57 45.0 3.13e-01 88.5% 84.9%
3236563 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.57 42.0 3.17e-01 78.8% 59.2%
3798829 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 40.0 2.66e-01 75.0% 19.6%
3220485 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 44.0 2.77e-01 94.2% 66.7%
3701882 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.56 39.0 3.25e-01 75.0% 41.1%
3636832 222.1.1.4 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT 0.56 42.0 2.89e-01 80.8% 85.1%
4988512 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.55 42.0 2.96e-01 84.6% 52.2%
3367891 109.4.1.1272 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif 0.55 40.0 2.49e-01 78.8% 84.1%
3791945 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.55 46.0 3.06e-01 96.2% 28.0%
4183868 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.55 41.0 3.60e-01 80.8% 64.6%
4564327 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.55 38.0 3.30e-01 75.0% 65.1%
3236725 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.54 40.0 2.55e-01 78.8% 55.4%
4998031 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.54 40.0 2.87e-01 84.6% 54.9%
3949584 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.53 42.0 3.06e-01 86.5% 70.0%
4478414 103.15.1.2 alpha arrays › RuvA-C › Mitoribosomal protein mS23 › Mitoribosomal protein mS23 › MRP-S25 0.53 39.0 2.96e-01 82.7% 51.1%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.52 45.0 2.64e-01 100.0% 14.2%
3921728 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 43.0 3.24e-01 88.5% 56.5%
4931347 5001.1.1.12 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Heliorhodopsin 0.52 46.0 2.89e-01 98.1% 21.1%
3575275 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.52 38.0 4.00e-01 88.5% 100.0%
3586391 3937.1.1.2 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.51 44.0 2.72e-01 96.2% 31.6%
4505972 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 39.0 2.46e-01 88.5% 19.1%
3708776 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.51 42.0 2.62e-01 94.2% 37.5%
5037750 3926.1.1.1 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D 0.50 44.0 2.94e-01 98.1% 42.6%
D2 medium residues 84-163
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1pvgA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.89 83.0 5.65e-01 100.0% 32.4%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3998214 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.88 83.0 5.63e-01 100.0% 32.9%
4945731 225.1.1.38 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DNA_gyraseB 0.88 81.0 5.64e-01 100.0% 33.9%
3789605 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.88 83.0 5.65e-01 100.0% 34.3%
1223478 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.87 80.0 5.33e-01 100.0% 29.3%
1223480 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.87 79.0 5.69e-01 100.0% 37.7%
3317524 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.87 82.0 5.76e-01 100.0% 39.9%
3594649 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.87 79.0 5.44e-01 100.0% 31.8%
4027049 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.86 82.0 5.49e-01 100.0% 31.7%
4617838 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.86 80.0 5.51e-01 100.0% 33.1%
3666034 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.72 60.0 5.35e-01 100.0% 65.5%
3461648 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.72 67.0 4.63e-01 100.0% 33.8%
4927454 386.1.1.418 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-FPG_IleRS 0.59 20.0 2.71e-01 96.2% 46.7%
3758777 246.2.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.53 46.0 2.95e-01 100.0% 31.4%
3514831 389.1.1.9 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › EGF_2 0.51 23.0 2.96e-01 100.0% 77.5%